
Vacation home rentals in Upstate South Carolina
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Top-rated vacation home rentals in Upstate South Carolina
Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Upstate South Carolina vacation home rentals
Family-friendly vacation home rentals

Large 3BR Asheville Home - Quiet Neighborhood!

Lake House and Dock Upscale and Immaculate

Lakefront Hartwell Home w/NEW Dock + NEW Fire Pit

City Dream 2BR 2BA w/ Patio Walk the Heart of GVL

Mountain Views w/ Hot Tub + Fire Pit – World’s Inn

Sandy Plains Fountain Home | King Bed | 3 MI TIEC

Nantahala River 2BR - Bear Cave Boat Parade

Patriot Point B, an inviting studio apartment
Vacation home rentals with a patio

Cozy Lake Hartwell Home 25 Minutes from Clemson

Studio in the heart of Greenville

Private mountain oasis with stunning views

Clemson/Anderson Lake Hartwell

PILOT COVE 1 BR - Modern Luxury w/ Nature!

Trout Stream Resort Home & Guest Cabin/Pavilion

Unique Lakefront Property Ideal for Multifamily or Large Family Stays

“forget the world” NC mountains
Vacation home rentals with a washer and dryer

Secluded mountain getaway near Blue Ridge Parkway

Lake junaluska resort, easy access and convenient

Walking distance to stadium with 4 parking spots!

Sunset Retreat - Big Deck, Mountain & Lake Views!!

Wright House Retreat

Cozy 3 bedroom home near Downtown Asheville

Stunning Mtn Views in Western NC W/new hot tub

Rocky Ridge Base Camp @ DuPont - Bike from House!
Destinations to explore
- Western North Carolina Vacation rentals
- Nashville Vacation rentals
- Atlanta Vacation rentals
- Myrtle Beach Vacation rentals
- Charleston Vacation rentals
- Gatlinburg Vacation rentals
- Charlotte Vacation rentals
- Hilton Head Island Vacation rentals
- Savannah Vacation rentals
- Pigeon Forge Vacation rentals
- Cape Fear River Vacation rentals
- North Myrtle Beach Vacation rentals
- Rentals with beach access Upstate South Carolina
- Beachfront rentals Upstate South Carolina
- Rentals with a sauna Upstate South Carolina
- Chalet rentals Upstate South Carolina
- Treehouse rentals Upstate South Carolina
- Rentals with a fireplace Upstate South Carolina
- Cottage rentals Upstate South Carolina
- Villa rentals Upstate South Carolina
- Bed and breakfasts Upstate South Carolina
- Rentals with a patio Upstate South Carolina
- Rentals with an accessible height toilet Upstate South Carolina
- Rentals with a fire pit Upstate South Carolina
- Rentals with an EV charger Upstate South Carolina
- Rentals with a hot tub Upstate South Carolina
- Fitness-friendly rentals Upstate South Carolina
- Hotel rentals Upstate South Carolina
- Serviced apartment rentals Upstate South Carolina
- Cabin rentals Upstate South Carolina
- Loft rentals Upstate South Carolina
- Smoking-friendly rentals Upstate South Carolina
- Family-friendly rentals Upstate South Carolina
- Rentals with a kayak Upstate South Carolina
- Rentals with pools Upstate South Carolina
- Resort rentals Upstate South Carolina
- Barn rentals Upstate South Carolina
- Rentals with a washer and dryer Upstate South Carolina
- Apartment rentals Upstate South Carolina
- House rentals Upstate South Carolina
- Rentals with outdoor seating Upstate South Carolina
- Rentals with breakfast Upstate South Carolina
- Pet-friendly rentals Upstate South Carolina
- Condo rentals Upstate South Carolina
- Nature eco lodge rentals Upstate South Carolina
- Tiny house rentals Upstate South Carolina
- Rentals with a home theater Upstate South Carolina
- Farmstay rentals Upstate South Carolina
- Rentals with lake access Upstate South Carolina
- Guesthouse rentals Upstate South Carolina
- Private suite rentals Upstate South Carolina
- Waterfront rentals Upstate South Carolina
- Townhouse rentals Upstate South Carolina
- Vacation home rentals United States
- Blue Ridge Parkway
- Gorges State Park
- Chimney Rock State Park
- Table Rock State Park
- The North Carolina Arboretum
- Tryon International Equestrian Center
- Lake Lure Beach and Water Park
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Jump Off Rock
- Victoria Valley Vineyards
- Discovery Island
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- Saint Paul Mountain Vineyards
- Burntshirt Vineyards
- City Scape Winery
- Overmountain Vineyards
- Russian Chapel Hills Winery
- Wellborn Winery