Vacation rentals with lake access in Upstate South Carolina

Find and book unique lake access rentals on Airbnb

Top-rated lake access rentals in Upstate South Carolina

Guests agree: these lake access rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Cottage in Lyman

4.99 out of 5 average rating, 233 reviews

Lakeside Retreat

With quiet views on Lyman Lake in South Carolina, this cottage is a great place to rest and relax. Close to Greenville and Spartanburg, SC. You’ll love my place because of the location, the ambiance, and the outdoor space. My place is good for couples, solo adventurers, and business travelers. GSP Airport-7 miles, Peace Center/Downtown Greenville-15 miles, Downtown Spartanburg-15 miles, Clemson Univ-42 miles, Furman Univ-14 miles, Tryon- 14 miles, Charlotte Airport-73 miles Asheville-46 mi

Aug 13 – 20

R2,277 ZAR per night

Guest favorite

Guesthouse in Abbeville

4.97 out of 5 average rating, 286 reviews

Quiet, Peaceful Loft in the Woods

Come relax for a getaway in our elegant guest loft! Located near the end of a quiet road with lots of wide open fields and beautiful tree lines! Our loft features a cute kitchenette, plenty of closet space, TV(YoutubeTV & Roku), an extremely comfortable bed! The loft is kept very clean and neat and will be stocked with all the essentials. Access to a beautiful 33' above ground pool! We are conveniently located about 5 miles from downtown Abbeville, and only a 10 minute drive to Erskine/Due West!

Jun 1 – 8

R1,107 ZAR per night

Guest favorite

Guesthouse in Anderson

5.0 out of 5 average rating, 218 reviews

Game Day Cottage in the Woods

Great location just off of I-85 at Exit 14; less than 8 miles to Clemson University, 7 miles to Green Pond Landing, and 1000 feet to Eighteen Mile Creek Boat Landing. Our cottage is located behind our home with a beautiful wooded setting. You will find a tranquil and secluded space, yet be close enough to our areas best restaurants and entertainment. We are also close enough to the Blue Ridge Mountain for a nice day trip. Please note our rate is $240 per night during Clemson home games.

Oct 1 – 8

R2,187 ZAR per night

Guest favorite

Tiny home in Greer

4.93 out of 5 average rating, 134 reviews

Shalom Tiny with Lake View - Greer, SC

Find Shalom, stay in our tiny home :) Reconnect with nature at this unforgettable escape on Lake Cunningham in Greer, SC. We are conveniently located by: - Historic Downtown Greer SC (drive: 10 min) - 23 minutes to Downtown Greenville - GSP airport (17 min) - Many parks & restaurants (5-15 min) You'll enjoy private access, comfy queen bed, ample living area, bathroom (w/ shower), WIFI & lake access. We have a kitchen ready for your cooking needs and a dedicated work space for remote workers.

Aug 2 – 9

R2,185 ZAR per night

Guest favorite

Home in Iva

4.98 out of 5 average rating, 156 reviews

Moonshine Bay

Your home away from home on South Carolina’s hidden gem, Lake Secession. Private wooded drive opens up to phenomenal lake view with shallow water entrance. Great for water sports, swimming, fishing and relaxation. If swimming isn’t for you, many beautiful reasonably priced golf courses are near by. Only 10 miles from Anderson & 36 miles to Clemson Stadium. Pull your boat to the dock or just enjoy some of our non-motorized lake toys. You’ll love it so much you want to come back year after year!

Mar 5 – 12

R3,003 ZAR per night

Guest favorite

Cottage in Gilbert

4.97 out of 5 average rating, 108 reviews

Peaceful, Lakefront Cottage

Our simple, unique (octagonal) cottage is ready for you to enjoy as you take in the serenity of Lake Murray! Have a meal on the spacious deck, go swimming/fishing from the dock, or just relax and observe the many fish, turtles and birds that live in this quiet cove. Our boat is on one side of the dock, and you’re welcome to use the other side for yours. There is a public boat ramp less than a mile away. Siesta Cove is the next cove over and has a general store and gas pumps for your boat.

Oct 11 – 18

R2,426 ZAR per night

Guest favorite

Guesthouse in Greenwood

4.94 out of 5 average rating, 180 reviews

Private Lakefront Cabin on Lake Greenwood

Get ready to enjoy beautiful lake views from this home! Private lake house right on Lake Greenwood. This recently remodeled guest house has one bedroom with a queen bed, full bath, and a large main room with a huge sectional sofa. Strong WIFI. 50" tv: Roku/Netflix/Hulu equipped. Enjoy 128ft of lakeshore including a fire pit, concrete pier, pergola seating area, beach, swimming area in lake, and putting green. 2 Kayaks available, free to use. 20ft pontoon for rent based on availability.

Jul 14 – 19

R3,175 ZAR per night

Guest favorite

Farm stay in Fountain Inn

4.94 out of 5 average rating, 139 reviews

The Fountain Moon Cabin on Hidden Pasture Farm

Such a unique property, do not miss this special place. We have so much to offer nature and animal lovers. Quiet and peaceful, The Fountain Moon Cabin at Hidden Pasture Unicorn Farm® is a breathtaking getaway to relax and enjoy nature or some good old fashioned gettin' back to center, your center. We are nestled on small pond with dock, canoe and paddle boat, plus fishing. We have trails and a wonderful agritourism visiting area and are the only visiting Unicorn Farm® in the world.

Oct 3 – 10

R2,223 ZAR per night

Guest favorite

Home in Easley

4.9 out of 5 average rating, 276 reviews

“Lake House Paradise” Waterfront Oasis

“Lake Paradise” is exquisitely furnished with 2 bedrooms and 1 and a half baths. Your Master Suite has its own screened in porch with private lake access. Wake up from your master suite to views from your bed of the water. Your en suite Master Bathroom has a large luxury marble shower. You will spend many hours of relaxation and peace in the most desirable location in the southeast. Visit Greenville SC's downtown just 15 minutes away. Clemson football Stadium is 20 miles away.

Dec 20 – 27

R2,744 ZAR per night

Guest favorite

Shipping container in Easley

4.99 out of 5 average rating, 188 reviews

Luxury lakefront container home + private dock

Start your next adventure at The Hive at Addison Farms! Upon arrival, you will be greeted with an incredible, picturesque view of Saluda Lake. This carefully designed romantic retreat is the ultimate getaway to unwind, reconnect, and relax. The Hive is conveniently located less than 20 mins. from Downtown Greenville, making it the perfect destination for a secluded weekend away, yet close enough to explore the wonderful places and activities in Upstate, SC.

Apr 22 – 29

R6,666 ZAR per night

Guest favorite

Farm stay in Easley

4.99 out of 5 average rating, 188 reviews

Dogwood Cottage- farm charm - Greenville & Clemson

A retreat in and of itself! This perfect, peaceful cottage is complete with full kitchen, bath and private porch. This converted llama barn elevates reclaimed woods and metals into a darling spot on our 24 acre farm. Serene and tranquil yet only minutes from downtown Greenville or Clemson activities. Nature galore with walking, fishing and even farm animals to meet. Our farm sits at the foot of the Blue Ridge with many quaint mountain towns to visit.

Jan 13 – 20

R1,945 ZAR per night

Superhost

Treehouse in Walhalla

4.96 out of 5 average rating, 735 reviews

The Majestic Treehouse romantic, luxury retreat

LIVE LIKE KINGS & PLAY LIKE KIDS in this extraordinary, award-winning treehouse. This luxury treehouse was designed by Seth Bolt (from the band NEEDTOBREATHE), who grew up on Bolt Farm. Larry Bolt (Seth's dad), proprietor, Eagle Scout, and licensed custom home builder has been building & remodeling homes for over 40 years in upstate SC. We are 32x Superhosts! Named the Most Popular Airbnb in SC!

Sep 18 – 25

R10,828 ZAR per night