
Pet-friendly vacation rentals in Upstate South Carolina
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Upstate South Carolina
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Upstate South Carolina pet-friendly home rentals
Pet-friendly house rentals

Sunset Point-Best view on Broadway - HOT TUB!

Wilderness - Lake, Dock, Hot Tub, Pet Friendly

Comfy Pelham Rd Gem | 1 Story | Kid & Dog Friendly

Airstream w/ Bathtub, River, & Hot Tub

Perfect 2 bed, remodeled home in quaint Pendleton

Spectacular home 1 mile from Main St Greenville!

Incredible waterfall mtn views| Hot Tub| Dogs Ok

Modern Wooded Retreat
Pet-friendly home rentals with a pool

College View Cottage & Saltwater Pool

Lakeside Family & Dog Retreat Awaits! DWC

Aframe Amazing Views Hot Tub Dog & Family Friendly

Modern Studio on a Private Horse Farm with a Pool

POOL open til Oct 12 HOT TUB Sleeps 11 Gameroom

Summer Swimming, Mountains, Vineyards, Pets Ok

Pet + Family Friendly 4BR Pool House Near Furman

A quiet place in the country
Private, pet-friendly home rentals

Tiny A-Frame Cabin Near Tallulah

Mountain Cabin on Creek at Jocassee Gorge.

The Old Log Cabin

Wahoo Cabin

Romantic Couples Dome W/Hot Tub & Great Views!

Cozy Mountain Cabin with amazing mountain views!

peaceful, cozy retreat | dog friendly | hot tub

Lunori | Loft 4 | Treehouse
Destinations to explore
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- Rentals with a hot tub Upstate South Carolina
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- Pet-friendly rentals South Carolina
- Pet-friendly rentals United States
- Blue Ridge Parkway
- Gorges State Park
- Chimney Rock State Park
- Table Rock State Park
- The North Carolina Arboretum
- Tryon International Equestrian Center
- Lake Lure Beach and Water Park
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Jump Off Rock
- Victoria Valley Vineyards
- Discovery Island
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- City Scape Winery
- Wellborn Winery
- Burntshirt Vineyards
- Overmountain Vineyards
- Russian Chapel Hills Winery
- Saint Paul Mountain Vineyards