House vacation rentals in Panama City
Find and book unique houses on Airbnb
Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama City house rentals
House rentals with a pool
Home in Provincia de Panamá Oeste
Luxurious beach front home in Veracruz
Home in Panama City
Cheerful Casa Duplex with swimming pool.
Home in Panamá
Fairway Estates, Santa María
Home in Panamá
Majestic Villa in Las Montañas
Home in Panamá
Beautiful house in Brisas del Golf
Home in Vacamonte
Cozy beach house close to town!
Home in Vacamonte
Adorable and cozy 3 bedroom house in Playa Dorada
Home in Panamá
Your cottage, Mountain Menus, awaits.
Weekly house rentals
Home in Obarrio
Apartment in Obarrio
Home in Panamá
Cozy 3BR Home in Ancon Hill's Lush Oasis
Home in Panamá
Cozy Cabin in Los Altos de Cerro Azul
Home in Panamá
Amazing mountain house
Home in Balboa
Spacious & cozy 4 bedroom home.
Home in Panama City
Casa Arad 2 rooms 10 min from the airport
Home in Panamá
Cozy House in Panama - 10 minutes from the Airport
Home in Panamá
entire home!
Private house rentals
Home in Gamboa
House in Renovated Gamboa, next to Panama Canal
Home in Panama City
LovelyviewPty House 15 minutes away from the airport.
Home in Panamá
Modern spacious house with a/c mins to the airport
Home in Panamá
Red House Altos de Cerro Azul
Home in Panama City
Blue Escape
Home in Balboa
Natural charm in the urban heart:Ancón, Balboa
Home in Panamá
house close to airport and shopping center
Home in Panamá
Modern 3bedroom house conveniently located
Quick stats about house rentals in Panama City
Total rentals
420 properties
Rentals with a pool
90 properties have a pool
Pet-friendly rentals
130 properties allow pets
Family-friendly rentals
160 properties are a good fit for families
Total number of reviews
4.5K reviews
Nightly prices starting at
R187 ZAR before taxes and fees
Destinations to explore
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- Rentals with an accessible height bed Panama City
- Villa rentals Panama City
- Hostel rentals Panama City
- Rentals with pools Panama City
- Smoking-friendly rentals Panama City
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- Rentals with a fireplace Panama City
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- Rentals with a home theater Panama City
- Hotel rentals Panama City
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- Monthly Rentals Panama City
- Rentals with breakfast Panama City
- Rentals with a fire pit Panama City
- Pet-friendly rentals Panama City
- Rentals with a sauna Panama City
- Rentals with an EV charger Panama City
- Rentals with a washer and dryer Panama City
- Bed and breakfasts Panama City
- Ski-in/ski-out rentals Panama City
- Rentals with beach access Panama City
- Kid-friendly rentals Panama City
- Rentals with a hot tub Panama City
- Rentals with outdoor seating Panama City
- Waterfront rentals Panama City
- Rentals with a patio Panama City
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