Skip to content
Sign up
Log in
Vacation rentals in Panama City

Vacation rentals in Panama City

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Panama City

Guests agree: these stays are highly rated for location, cleanliness, and more.

  • Apartamento Completo+Traslado Aeropuerto(Opcional)
    SUPERHOSTEntire apartment · 3 guests · 1 bed · 1 bath
    Apartamento Completo+Traslado Aeropuerto(Opcional)

    En español: Todos las personas son bienvenidas a este hermoso y cómodo apartamento. Te sentirás muy a gusto. Es un apartamento confortable, muy bien iluminado y limpio. Personalmente los atenderé desde el aeropuerto hasta el apartamento (adicional). In English: All people are welcome to this beautiful and comfortable apartment. You will feel very comfortable. It is a comfortable apartment, very well lit and clean. Personally I will assist you from the airport to the apartment (additional).

    What guests are saying:

    “In mid-March 2020, when the corona crisis was also in full swing in Panama and people were afraid of Europeans due to a possible risk of infection, Estefanía rented her apartment to us. She made it possible for us to check in very early, was always available for us via SMS / Whatsa ... and was incredibly understanding. The apartment was ideal for this situation in which we only went out for shopping. With air conditioning, a ceiling and a standing fan, a fully equipped kitchen and Netflix, it was good to endure the days. It was a great help that we were able to use the airport shuttle they offered at the end. I would like to thank you for your trust and your help, Estefanía! Muchas gracias para todo !!!”

  • Casa Amador: Your Home in Panama
    SUPERHOSTEntire apartment · 6 guests · 2 beds · 2 baths
    Casa Amador: Your Home in Panama

    Quiet living, green space and amazing views of the skyline and the Panama Canal plus a pool + gym. Restaurants are walking distance, downtown is also close. We're 5 minutes to historic Casco Viejo for nightlife, 10 minutes to Albrook for the best shopping, and 30 mins to the international airport. There are 2 balconies, an open kitchen, and both bedrooms have their own bathroom. Laundry is onsite + fast internet. Uber works in the area, but we recommend to rent a car or hire a driver.

    What guests are saying:

    “The views from the apartment are spectacular and unrivaled. You will not be disappointed. At the bottom of the hill is the Amador Causeway with plenty of places for food and entertainment. In fact, it is THE SPOT for locals on the weekend. It’s a great alternative if you don’t want to be downtown. (And to get downtown is $5-7 ride on Uber). It’s practical for families: there’s a bath for each room (although we didn’t bother to use one of the showers because it seemed difficult) and a nice pool and lounge area that we had all to ourselves on our “rest” day between excursions. The (FREE!) laundry came in handy when it was time to pack and return home. I wouldn’t hesitate to stay again.”

  • LUXURY STUDIO in Casco Viejo, Ocean & City View #3
    SUPERHOSTEntire apartment · 4 guests · 2 beds · 1 bath
    LUXURY STUDIO in Casco Viejo, Ocean & City View #3

    5 star hotel like suite, without a 5 star price tag. Located in the historic neighborhood of Casco Viejo, this is the most popular area in Panama City! This spacious Luxury Suite has 1 queen size bed, a fold down sofa bed, & a couch that can sleep between 1-4 people. This is a premium location matched with a premium apartment. Furniture & appliances are brand new!VERY NOISY til 4am on Thurs,Fri,Sat,Sund & Mon night with Nightclub next door.Make sure you're ok with this before booking

    What guests are saying:

    “We had a great stay. Shanti was such a great host, very responsive with great tips. Considering the situation in the middle of a pandemic we spent a lot more time inside than we anticipated and we really appreciated having such a comfortable place to stay. The balcony and view was very nice and the apartment was clean and stylish. Even managed to exercise inside our room when the shutdowns were happening. Would definitely recommend staying here, great position to be able to work to many interesting sites and very safe area. Check out the great food and coffee nearby! Excellent recommendation of lo que hay it was our favourite place to eat! Thanks for everything, hope to visit Panama again!”

Vacation rentals for every style

Get the amount of space that is right for you.

  • Homes
  • Hotels
  • Unique stays

Popular amenities for Panama City vacation rentals

  • Kitchen
  • Wifi
  • Pool
  • Free parking on premises
  • Air conditioning

Other great vacation rentals in Panama City

Private cottage in the heart of the city
SUPERHOSTEntire guesthouse
Private cottage in the heart of the city
Price:R1,462 ZAR / night
Cozy Cottage in Cerro Azul
Entire cottage
Cozy Cottage in Cerro Azul
Price:R3,440 ZAR / night
Amazing apartment with terrace and jacuzzi P5
Entire condominium
Amazing apartment with terrace and jacuzzi P5
Price:R1,703 ZAR / night
Full Bedroom + rooftop in Casco Viejo, oceanfront
SUPERHOSTPrivate room
Full Bedroom + rooftop in Casco Viejo, oceanfront
Price:R1,290 ZAR / night
Charming apt in Panama Old Quarter
Entire apartment
Charming apt in Panama Old Quarter
Price:R1,032 ZAR / night
Hermosa Habitación Vista
Private room
Hermosa Habitación Vista
Price:R430 ZAR / night
Expectacular vista y comodidad
SUPERHOSTEntire apartment
Expectacular vista y comodidad
Price:R1,462 ZAR / night
Comfortable Private Room w/ Panama city view
SUPERHOSTPrivate room
Comfortable Private Room w/ Panama city view
Price:R464 ZAR / night
Beautiful and Cozy Apartment in Casco Viejo
SUPERHOSTEntire apartment
Beautiful and Cozy Apartment in Casco Viejo
Price:R2,236 ZAR / night
CasaDíaz: Private room in Ancon Hill (Cerro Ancón)
SUPERHOSTPrivate room
CasaDíaz: Private room in Ancon Hill (Cerro Ancón)
Price:R602 ZAR / night
Casco Viejo Fabulous Old Tower 360° View Penthouse
SUPERHOSTEntire apartment
Casco Viejo Fabulous Old Tower 360° View Penthouse
Price:R5,589 ZAR / night
Villa la Vista extraordinary Panoramic View & Pool
SUPERHOSTEntire villa
Villa la Vista extraordinary Panoramic View & Pool
Price:R3,422 ZAR / night
Show all