
Guesthouse vacation rentals in Panama City
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Top-rated guesthouse rentals in Panama City
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama City guesthouse rentals
Family-friendly guest house rentals

Quiet Room 3/ guesthouse Panamá

Cabin inside a beautiful property.

Comfort & Privacy room 8/Panamá

Private Ensuite Room

Cozy room7/ GuesthousePanamá

Casa Relic - Room #2 Mixed Dormitory

Private Room in Smart Hostel

Spectacular room for 4 people, two beds
Guest house rentals with a patio

A house on the river in Cerro Azul, Panama

Private Room 5/guesthouse Panamá

Accommodation near Tocumen Airport

the refuge

Family Room 6/Guesthouse Panamá

Private Room 1, Bella Vista/Panamá

Triple Room in Smart Hostel

Private suite
Guest house rentals with a washer and dryer

take a break in a quiet place

My home

WHERE YOYI

Cozy apartment with a hot tub

Private cabin and CasaMomote river, Loma Limón.

Room, nature, sauna and eveything, near the sea.

Rent a furnished room in San Antonio

Gamboa Toucan Apartment casa # 126
Quick stats about guesthouse rentals in Panama City
Total rentals
70 properties
Nightly prices starting at
R173 ZAR before taxes and fees
Total number of reviews
1.4K reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
20 properties allow pets
Rentals with a pool
10 properties have a pool
Destinations to explore
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- Villa rentals Panama City
- Rentals with a hot tub Panama City
- Hotel rentals Panama City
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- Guesthouse rentals Panama
- Things to do Panama City
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- Things to do Panamá Province
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- Nature and outdoors Panamá Province
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- Art and culture Panamá Province
- Things to do Panama
- Food and drink Panama
- Nature and outdoors Panama
- Tours Panama
- Sports activities Panama
- Art and culture Panama
- Sightseeing Panama