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Boutique hotel vacation rentals in Florida Panhandle

Find and book unique boutique hotel rentals on Airbnb

Top-rated boutique hotel rentals in Florida Panhandle

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

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Hotel room in Panama City Beach

4.94 out of 5 average rating, 16 reviews

Beachfront HONEYMooN pool,kitchen,door check-in!

DOOR CHECK IN -PRIVATE ROOM NOT SHARED-DOOR CHECKIN 3PM OR LATER,LATE CHECK OUT BY 12 NOON.GREAT RATES OCEAN FRONT CONDO/HOTEL type ROOM.STEPS FROM THE OCEAN. MILLLON DOLLAR VIEWS IN A GREAT LOCATION. Perfectly Cozy Beach Front Condo with pool : 14401 Front Beach Rd, Panama City Beach,Florida. (2ND FLOOR #213) FREE PARKING.BEAUTIFUL VIEWS ON THE LOOKOUT ROOFTOP AND BALCONIES.NEAR RESTAURANTS AND ATTRACTIONS.Washateria on site. Swimmg pool. LATE CHECK IN 3PM UNTIL MIDNIGHT OR LATER BY REQUEST!!

The living area features a dark leather sofa and a rustic wooden coffee table, complemented by a flat-screen television mounted on the wall. Light streams in through large windows, accentuating the natural wood flooring and inviting ambiance of the space.

Hotel room in Apalachicola

4.95 out of 5 average rating, 197 reviews

The Sea Glass Suite at The Riverwood Suites

At Riverwood Suites it isn’t just a room, it’s an experience. The rustic exterior may surprise you but when you walk into your suite you are instantly captivated by the chic upcycled decor. The modern amenities make you feel right at home. You enjoy wine on the veranda or enjoy a cup of coffee in the back garden. (Keurig coffee maker, coffee, tea, creamer, and sugar are also provided) Everything you need is provided: toiletries, linens, kitchenware, even a full size refrigerator with ice maker.

A spacious suite features rustic wooden flooring and natural light from multiple windows. Modern amenities include a full-size refrigerator, microwave, and kitchenette. A cozy seating area is arranged around a traditional side table, while a comfortable bed invites relaxation against a stylish backdrop.

Hotel room in Apalachicola

4.93 out of 5 average rating, 163 reviews

The Moonlight Suite at The Riverwood Suites

At Riverwood Suites it isn’t just a room, it’s an experience. The rustic exterior may surprise you but when you walk into your suite you are instantly captivated by the chic upcycled decor. The modern amenities make you feel right at home. You enjoy wine on the veranda or enjoy a cup of coffee in the back garden. (Keurig coffee maker, coffee, tea, creamer, and sugar are also provided) Everything you need is provided: toiletries, linens, kitchenware, even a full size refrigerator with ice maker.

Top guest favorite

A living area features a dark leather sofa and a pale blue armchair positioned near a rustic coffee table. A flat-screen television is mounted on the wall. Natural light fills the space through large windows, complemented by a stylish lamp and decorative artwork.

Hotel room in Apalachicola

4.97 out of 5 average rating, 115 reviews

The Pearl Suite at The Riverwood Suites

At Riverwood Suites it isn’t just a room, it’s an experience. The rustic exterior may surprise you but when you walk into your suite you are instantly captivated by the chic upcycled decor. The modern amenities make you feel right at home. You enjoy wine on the veranda or enjoy a cup of coffee in the back garden. (Keurig coffee maker, coffee, tea, creamer, and sugar are also provided) Everything you need is provided: toiletries, linens, kitchenware, even a full size refrigerator with ice maker.

A spacious room features a four-poster bed with crisp white linens. Tropical-patterned wallpaper adds a vibrant touch, complemented by large windows covered with leafy curtains. A desk with a gold lamp and a side table with lamps complete the bright, inviting space.

Hotel room in Pensacola

4.83 out of 5 average rating, 75 reviews

Santiago room at Lily Hall- A Boutique Hotel

For an evening or for a while, we welcome you to Lily Hall. Although our building has a rich history, each of our fifteen rooms comes equipped with modern comforts. We don’t have a concierge on site, but we’re always here to make your stay seamless. The Santiago rooms are appointed with a king-size bed, coffee service, 50inch TCL Roku TV, complimentary WiFi, premium bath amenities, spa-like walk-in shower, hair dryer, steamer, and iHome. The Santiago rooms are best for the short trip traveler.

The beachfront property is positioned close to the sandy shore, with vibrant blue ocean waters visible in the background. Umbrellas and sunbathers can be seen on the beach, while the building features a mix of architectural styles, showcasing a coral pink exterior.

Hotel room in Saint George Island

4.84 out of 5 average rating, 243 reviews

Island Suites - Room 4 - 2 Queen Beds

The Island Suites is located on St. George Island on the beach front within walking distance to the majority of restaurants and shops. Each room has a private balcony overlooking the Gulf of Mexico, 1 king or 2 queen beds, refrigerator, microwave, in-room coffee, guest room amenities, cable and internet. There are 2 handicap accessible rooms with 2 queen beds or 1 king. When making your reservation please note there are 8 different rooms so if one is not available scroll through the others.

A cozy bedroom features a California King bed dressed with floral bedding, complemented by two bedside lamps with turquoise bases. A decorative wooden headboard and a vibrant floral artwork enhance the rustic charm. A vintage trunk serves as an accent piece at the foot of the bed.

Hotel room in Apalachicola

4.93 out of 5 average rating, 161 reviews

The Coral Suite at Riverwood Suites

At Riverwood Suites it isn’t just a room, it’s an experience. Picture it: You drive up, the rustic exterior may take you by surprise. As you walk into your suite you notice the full size refrigerator and the California King bed. Before you hit the hay, you grab a glass from the kitchenette and head to the veranda, while looking out over downtown. Morning is pleasant with the Keurig coffee maker. You relax in the back garden while you wait for your spa services from Simply Bella Aesthetics.

A light and airy room features a spacious bed with crisp white bedding. Two bedside lamps are positioned on minimalist nightstands. A small dining table is set for two near a set of glass doors leading to outdoor light, while framed artwork adorns the walls.

Hotel room in Pensacola

Luxury Waterfront Boutique Hotel

Settle into one of our Balcony rooms with extra space and enjoy its exclusive amenities. These rooms have custom appointments ranging from a small dining area, built-in wardrobe, original art, handmade pieces by local potters, ensuite bathrooms featuring a walk-in showers and private toilets, a balcony with seating and king-sized beds beautified in white Peacock Alley bedding. Enjoy the sunrise with a Nespresso or glass of Prosecco while looking out over Pensacola Bay.

The covered deck features a solid roof supported by wooden beams. White railings enclose the space, while two chairs and a small table create a cozy seating area. Natural light filters through the large window, enhancing the inviting outdoor ambiance.

Hotel room in Fort Walton Beach

4.89 out of 5 average rating, 234 reviews

The Guest Room & Back Deck

The Guest Room is a spacious 12X15 foot room. In addition, it has a huge 10X8 foot bathroom, a walk-in closet, and a 10X20 foot covered deck all for your private use. You have your own private entrance to your room, and the room is locked off from the rest of the house. There is a 4.7 cu. ft. refrigerator, a microwave, two hotplates, a coffee maker, a toaster, and a gas grill with a side burner. There is a spacious backyard that is more like a forest than a yard.

A historic yellow home with white trim stands prominently among lush green trees. The front yard features well-maintained grass and palm trees, while a sign is visible near the entrance. The clear blue sky adds to the inviting appearance of the property.

Hotel room in Apalachicola

5 out of 5 average rating, 4 reviews

Coombs House Inn & Suites -SNEDD

You won’t want to leave this charming, one-of-a-kind place that is just a short walk to downtown Apalachicola. Feel free to leave your car behind and walk the beautiful historic downtown or feel free to rent one of our beach cruiser bikes and go explore everything from the finest seafood to some of the best breweries. Don't get back too late as ghosts are known to roam the hallways of this historic inn at night. This Suite has two Double beds.

A beachfront property is shown from an aerial view, featuring a pink structure with balconies facing the sandy beach and turquoise waters. Beach umbrellas and sunbathers are visible along the shore, highlighting the outdoor recreational area.

Hotel room in Saint George Island

4.76 out of 5 average rating, 248 reviews

Island Suites - Room 6 - 1 King Bed

The Island Suites is located on St. George Island on the beach front within walking distance to the majority of restaurants and shops. Each room has a private balcony overlooking the Gulf of Mexico, 1 king or 2 queen beds, refrigerator, microwave, in-room coffee, guest room amenities, cable and internet. When making your reservation please note there are 8 different rooms so if one is not available scroll through the others.

A beachfront property is shown with a light-colored structure nestled among sandy dunes. The clear blue Gulf waters and sky create a serene backdrop. Beachgoers and umbrellas dot the shore, indicating a relaxed coastal environment.

Hotel room in Saint George Island

4.83 out of 5 average rating, 296 reviews

Island Suites - Room 8 - 1 King Bed

The Island Suites is located on St. George Island on the beach front within walking distance to the majority of restaurants and shops. Each room has a private balcony overlooking the Gulf of Mexico, 1 king or 2 queen beds, refrigerator, microwave, in-room coffee, guest room amenities, cable and internet. When making your reservation please note there are 8 different rooms so if one is not available scroll through the others.

Vacation rentals for every style

Get the amount of space that is right for you

Houses

A space thats all yours, with room for everyone

Cottages

Quaint homes, peaceful surroundings

Apartments

Convenient locations with everyday essentials

Popular amenities for Florida Panhandle boutique hotel rentals

Free parking on premises

Air conditioning

Family-friendly boutique hotels rentals

The spacious sleeping area features a floating King bed with white bedding and decorative pillows. A contemporary light fixture hangs above. A seating area is visible in the background, along with a mini-kitchen. Natural light floods in from the sliding glass doors leading to the courtyard.

Hotel room in Fairhope

4.92 out of 5 average rating, 145 reviews

Cool, cozy, contemporary and romantic! Location!

A cozy bedroom features a California King bed dressed with floral bedding, complemented by two bedside lamps with turquoise bases. A decorative wooden headboard and a vibrant floral artwork enhance the rustic charm. A vintage trunk serves as an accent piece at the foot of the bed.

Hotel room in Apalachicola

4.93 out of 5 average rating, 161 reviews

The Coral Suite at Riverwood Suites

The living area features a dark leather sofa and a rustic wooden coffee table, complemented by a flat-screen television mounted on the wall. Light streams in through large windows, accentuating the natural wood flooring and inviting ambiance of the space.

Hotel room in Apalachicola

4.95 out of 5 average rating, 197 reviews

The Sea Glass Suite at The Riverwood Suites

A beachfront property is shown from an aerial view, featuring a pink structure with balconies facing the sandy beach and turquoise waters. Beach umbrellas and sunbathers are visible along the shore, highlighting the outdoor recreational area.

Hotel room in Saint George Island

4.76 out of 5 average rating, 248 reviews

Island Suites - Room 6 - 1 King Bed

A spacious suite features rustic wooden flooring and natural light from multiple windows. Modern amenities include a full-size refrigerator, microwave, and kitchenette. A cozy seating area is arranged around a traditional side table, while a comfortable bed invites relaxation against a stylish backdrop.

Hotel room in Apalachicola

4.93 out of 5 average rating, 163 reviews

The Moonlight Suite at The Riverwood Suites

The covered deck features a solid roof supported by wooden beams. White railings enclose the space, while two chairs and a small table create a cozy seating area. Natural light filters through the large window, enhancing the inviting outdoor ambiance.

Hotel room in Fort Walton Beach

4.89 out of 5 average rating, 234 reviews

The Guest Room & Back Deck

Top guest favorite

A living area features a dark leather sofa and a pale blue armchair positioned near a rustic coffee table. A flat-screen television is mounted on the wall. Natural light fills the space through large windows, complemented by a stylish lamp and decorative artwork.

Hotel room in Apalachicola

4.97 out of 5 average rating, 115 reviews

The Pearl Suite at The Riverwood Suites

A beachfront property is shown with a light-colored structure nestled among sandy dunes. The clear blue Gulf waters and sky create a serene backdrop. Beachgoers and umbrellas dot the shore, indicating a relaxed coastal environment.

Hotel room in Saint George Island

4.83 out of 5 average rating, 296 reviews

Island Suites - Room 8 - 1 King Bed

Boutique hotels rentals with a patio

A historic two-story building features a yellow exterior with white trim, surrounded by well-maintained lawns and mature palm trees. A sign indicating the property name is prominently visible in the front garden, contributing to the welcoming atmosphere of the location.

Hotel room in Apalachicola

4.65 out of 5 average rating, 23 reviews

Coombs House Inn & Suites - NK

A historic yellow-painted inn is presented with white trim, surrounded by lush green lawns and palm trees. The property features multiple windows and a welcoming front porch, inviting guests to enjoy the outdoors. A sign indicating the inn's name is visible near the entrance.

Hotel room in Apalachicola

4.17 out of 5 average rating, 6 reviews

Coombs House Inn & Suites - NDD

A charming historic inn is presented, featuring a yellow exterior with white trim. Surrounded by lush green lawns and palm trees, the property offers a welcoming facade. A sign identifying the inn is positioned in front, along with a shaded seating area under a canopy.

Hotel room in Apalachicola

4.56 out of 5 average rating, 61 reviews

Coombs House Inn & Suites - NQ

A charming yellow house with white trim is surrounded by lush green lawns and palm trees. The front porch features a small seating area, and a sign indicates the property's name. A paved pathway leads up to the entrance, enhancing accessibility.

Hotel room in Apalachicola

4 out of 5 average rating, 5 reviews

Coombs House Inn & Suites- SNDD

A historic two-story home is shown, featuring yellow siding and white trim. Lush green lawns surround the property, with palm trees providing shade. A sign in front indicates the name of the inn. The clear blue sky adds to the inviting appearance of the residence.

Hotel room in Apalachicola

Coombs House Inn & Suites - SNQ

A stately yellow house with white trim is surrounded by lush greenery and palm trees. A sign reading 'Coucou' stands at the edge of a neatly maintained lawn. The building features multiple windows and a covered patio, showcasing classic architectural details.

Hotel room in Apalachicola

4 out of 5 average rating, 3 reviews

Coombs House Inn & Suites - NHQ

A charming yellow historic inn is surrounded by lush greenery and palm trees. The building showcases multiple windows and a welcoming front porch, with a sign positioned in the front yard. A walkway leads up to the entrance along a neatly maintained lawn.

Hotel room in Apalachicola

4.5 out of 5 average rating, 6 reviews

Coombs House Inn & Suites - SNK

Other boutique hotel vacation rentals

A cozy bedroom features a California King bed dressed with floral bedding, complemented by two bedside lamps with turquoise bases. A decorative wooden headboard and a vibrant floral artwork enhance the rustic charm. A vintage trunk serves as an accent piece at the foot of the bed.

Hotel room in Apalachicola

4.93 out of 5 average rating, 161 reviews

The Coral Suite at Riverwood Suites

The living area features a dark leather sofa and a rustic wooden coffee table, complemented by a flat-screen television mounted on the wall. Light streams in through large windows, accentuating the natural wood flooring and inviting ambiance of the space.

Hotel room in Apalachicola

4.95 out of 5 average rating, 197 reviews

The Sea Glass Suite at The Riverwood Suites

A beachfront property is shown from an aerial view, featuring a pink structure with balconies facing the sandy beach and turquoise waters. Beach umbrellas and sunbathers are visible along the shore, highlighting the outdoor recreational area.

Hotel room in Saint George Island

4.76 out of 5 average rating, 248 reviews

Island Suites - Room 6 - 1 King Bed

A spacious suite features rustic wooden flooring and natural light from multiple windows. Modern amenities include a full-size refrigerator, microwave, and kitchenette. A cozy seating area is arranged around a traditional side table, while a comfortable bed invites relaxation against a stylish backdrop.

Hotel room in Apalachicola

4.93 out of 5 average rating, 163 reviews

The Moonlight Suite at The Riverwood Suites

The covered deck features a solid roof supported by wooden beams. White railings enclose the space, while two chairs and a small table create a cozy seating area. Natural light filters through the large window, enhancing the inviting outdoor ambiance.

Hotel room in Fort Walton Beach

4.89 out of 5 average rating, 234 reviews

The Guest Room & Back Deck

Top guest favorite

A living area features a dark leather sofa and a pale blue armchair positioned near a rustic coffee table. A flat-screen television is mounted on the wall. Natural light fills the space through large windows, complemented by a stylish lamp and decorative artwork.

Hotel room in Apalachicola

4.97 out of 5 average rating, 115 reviews

The Pearl Suite at The Riverwood Suites

A view of the beachfront property showcases a vibrant pink building with a metal roof. The soft sand beach is visible, dotted with umbrellas and beachgoers enjoying the tranquil Gulf waters. Captivating blue skies provide a serene backdrop.

Hotel room in Saint George Island

4.81 out of 5 average rating, 233 reviews

Island Suites - Room 5 - 1 King Bed

A beachfront property is shown with a light-colored structure nestled among sandy dunes. The clear blue Gulf waters and sky create a serene backdrop. Beachgoers and umbrellas dot the shore, indicating a relaxed coastal environment.

Hotel room in Saint George Island

4.83 out of 5 average rating, 296 reviews

Island Suites - Room 8 - 1 King Bed

Destinations to explore