Hotel vacation rentals in Panama

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Top-rated hotel rentals in Panama

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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Superhost

The private patio area features a wooden deck with seating for four, consisting of stylish wicker chairs and a small table. Lush green plants frame the space, creating an inviting outdoor retreat surrounded by natural landscaping.

Hotel room in Panamá

4.86 out of 5 average rating, 7 reviews

Avani Eco Hotel ~ Romantic Nature Getaway ~ Patio!

Step into the comfort of this beautiful queen suite in the high-end, eco-friendly Avani Boutique Hotel, offering easy access to sandy beaches and the many stunning amenities and activities of Contadora Island. Spend the day exploring this breathtaking island and then retreat to the attractive suite whose stylish design and scenic surroundings will mesmerize you. ✔ Comfy Queen Bed ✔ Spa-Like Bathroom ✔ Private Patio ✔ Wi-Fi ✔ Hotel Amenities (Breakfast, Transport, Activities) Learn more below!

Superhost

The restaurant terrace features wooden tables and chairs arranged around a central vase of tropical flowers. A scenic view of the water and surrounding greenery is visible through the open space, where natural light enhances the welcoming environment.

Hotel room in Palo Seco

5 out of 5 average rating, 3 reviews

Waterfront | Fish restaurant | Room #4

Notre hotel Ocekepala vous accueille au coeur du village de pêcheurs de Palo Seco (entre Mariato et Torio). Situé en front de mer, les plages sauvages vous attendent pour de belles aventures. Le soir, rendez vous au bout du ponton pour admirer le soleil se coucher sur l'île de Cebaco. Venez ensuite déguster de délicieux produits de la mer (poisson entier, langoustes, burger poisson et notre spécialité la paella) cuisinés par notre équipe. Nous avons hâte de vous accueillir! Karine & Brice.

Superhost

A serene garden setting features lush greenery, colorful flowers, and a natural water fountain flowing over stones. Seating areas with small tables and chairs complement the peaceful atmosphere, while vibrant plant life surrounds the tranquil scene.

Hotel room in Boquete

4.73 out of 5 average rating, 15 reviews

La Residencia - Family Room

Just a 10 minute walk to downtown Boquete this modern & contemporary furnished room for max 4 people is located on the second floor in an extraordinary tastfully furnished mansion. The beautiful terrace with a natural waterfountain is surrounded by gorgeous green areas inside a birdparadise. Stylish room (2 Queen-Size/Orthopedic mattress) with private bathroom & walkin closet. Huge lobby with different sitting areas. Big shared kitchen, dining area, free parking, fast Wifi, cable TV, Netflix.

Guest favorite

The outdoor porch is illuminated by warm lighting, featuring comfortable wooden seating and a hammock. Lush greenery surrounds the area, enhancing the natural ambiance. A lantern stands nearby, adding subtle charm to the inviting outdoor space.

Hotel room in Cambutal

4.8 out of 5 average rating, 20 reviews

Cedro Espino Cabana, Ocean view, Steps From Beach

No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Guest favorite

A tranquil swimming pool is set amidst lush greenery, with various trees surrounding the area. Lounge chairs are positioned on the pool deck, offering a peaceful spot to relax. Nearby, a gazebo can be seen, providing shaded seating options.

Hotel room in PA

4.91 out of 5 average rating, 34 reviews

Villa Coco King Room

Villa Coco is a beautiful boutique hotel in Santa Catalina, only footsteps away of the world known surf break “La Punta” and Unesco world heritage Coiba island. The carefully designed cabañas, provide a space of tranquility and a sense of timelessness. Unwind in the hammocks and canvas chairs on your private terrace, dwell on reading your favorite book or sip on a cool drink from the bar. Our Restaurant “Ai Mamita” offers different kinds of meat, fresh seafood and other tasty delights.

Superhost

A small table and chair set are positioned on a balcony, with a vase of flowers at the center. In the background, a panoramic ocean view is framed by lush greenery and colorful umbrellas near the pool area.

Private room in Taboga Island

4.9 out of 5 average rating, 61 reviews

Eco Lodge Garden Room 5 Oceanview Plunge Pool

Experience Cerrito Tropical Eco Lodge. Relax. Enjoy our refreshing plunge pool. Natural hillside location, interpretive garden. Jaw dropping oceanview from pool/deck (pool chairs, UV umbrellas). Walk to the beach. Comfortable ground floor room with bathroom, airconditioning, free Wifi and local TV. Exterior oceanview /gardenview balcony. Birdwatchers can spot up to 124 species recorded on Taboga. Artisanal pizza made onsite. Local taxes 10%. No pets in the Garden Rooms.

Guest favorite

A spacious room features a comfortable bed with soft white linens, complemented by a minimalistic design. Large windows allow natural light to fill the space, while a sleek wooden ceiling adds warmth. A small table with two chairs and a vase of flowers is positioned beside the bed.

Hotel room in Boquete

4.91 out of 5 average rating, 11 reviews

Deluxe King

We offer 5 Deluxe Double Queen rooms with two Queen beds and 4 Deluxe King rooms with one King bed. All include A/C, daily cleaning, mini-fridge, safe, and private bathroom — ideal for a comfortable and convenient stay in Boquete. Contamos con 5 habitaciones Deluxe Double Queen con dos camas Queen y 4 Deluxe King con una cama King. Todas incluyen A/C, limpieza diaria, mini nevera, caja fuerte y baño privado — ideales para una estadía cómoda y práctica en Boquete.

Top guest favorite

The three-story, contemporary building features multiple balconies and outdoor spaces, surrounded by lush greenery. Light wood accents and large windows highlight the design, while the metal roof complements the natural setting. Pathways lead to various entry points, enhancing accessibility to this serene retreat.

Hotel room in Bastimentos Island

5 out of 5 average rating, 16 reviews

Agradecer: Surf lover's dream

Agradecer, or to give thanks, is our three person ocean view apartment, flanked by flowers, and located directly below the Yoga Shala. Equipped with a Caribbean Queen and Twin memory foam mattresses, this is a great space for a family or group of friends. Enjoy a yoga class, hike in the jungle or relax on the porch. Breakfast is vegetarian, organic, served over the water, & INCLUDED free in your stay! Only 5 min by boat to world class surf!

Guest favorite

Hotel room in Playa Coronado

4.86 out of 5 average rating, 37 reviews

My spot - Panama

Indulge in charm at this adorable suite, boasting a picturesque pool view. Steps away from Panama's premier golf course and just 750m from the beach, it's an ideal retreat for nature lovers. Enjoy resort luxuries like four restaurants, a bar, golf, gym, beach club, tennis, and kids club. Whether relaxing or exploring, this sanctuary offers pampering and adventure in equal measure.

Superhost

Large green doors open to a charming balcony, revealing a view of a red-tiled roof and a small table with two chairs. A soft sofa is positioned nearby, complementing the inviting atmosphere of the space.

Hotel room in Panamá

4.83 out of 5 average rating, 87 reviews

Corcho rooms #2 - king room with balconies

Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant an serviced guest rooms upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the building around are restored and the neighborhood is safe.

Superhost

A sandy area is framed by lush greenery and palm trees, leading to the beach. Strings of lights are suspended gently above, and a cozy beach house with blue siding is visible on the right. The horizon features the calm ocean under a clear sky.

Private room in Bocas del Toro Province

5 out of 5 average rating, 7 reviews

MAR ONDA, the Eco-elegance Resort in Bluff Beach

Only a few steps to the beach, this resort was custom built to be in harmony with it's natural surroundings. Powered by the sun and watered by the rain, Mar onda is self-sufficient while still providing all the comforts of home. Enjoy fresh locally grown food and the comfort and craftsmanship of the accommodations.

Superhost

Private room in Bocas del Toro

5 out of 5 average rating, 14 reviews

The Firefly B&B oceanfront,pool Adults only Rm #1

This listing is for Room 1 in our b&b. Room 1 has a private oceanfront deck, private bathroom with hot water shower, four poster bed with net, industrial ceiling fan, queen size memory foam mattress, in room safe and seating area. Room 1 is located next to the yoga space and restaurant.