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Guesthouse vacation rentals in Panama

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Panama guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
Guesthouse in Nueva Gorgona
4.99 out of 5 average rating, 72 reviews

Beautiful Casita-Paradise in Panama, Nueva Gorgona

DavidRating, 5 stars3 months ago
Linda and her husband Russ were wonderful hosts. Linda was great communicating prior to my arrival, and very accommodating when my travel plans resulted in an earlier than expected arrival. Russ even gave me a ride to pick up a rental car at an airport 37km away. Beautiful Casita describes the facility perfectly. The casita itself and the grounds were beautiful, comfortable, and peaceful. If you're planning a trip to the Nueva Gorgona/Coronado area, I highly recommend Beautiful Casita. I will book with them again for sure.
Guesthouse in Bocas del Toro Province
5 out of 5 average rating, 4 reviews

Las Palmas Casita at Bluff Beach Retreat

MarcRating, 5 stars27 months ago
We really enjoyed our vacation, and we can definitely renommend Bluff Beach Retreat. Karen and Steve were very helpful and took good care of us. The nature and the beautiful sorroundings were amazing. A boat trip with Luis, arranged by Karen, is something you shouldn’t miss out - a fantastic guy:)
Guesthouse in Boquete
5 out of 5 average rating, 10 reviews

Vista a Baru

ElliotRating, 5 stars5 months ago
What a magical place! Lily and bob were warm, welcoming, and helpful hosts. We had a couple hiccups along the way and they were extremely responsive in helping us. Their property and the surrounds could not be any more beautiful. We hope to be back soon.
Guesthouse in Coloncito
4.95 out of 5 average rating, 19 reviews

Beautiful Casita-Paradise in Panama, Nueva Gorgona

Dustin And GingerRating, 5 stars20 months ago
Love this place! Comfortable and close to everything. Russ and Linda are great to work with. We will be back!
Guesthouse in Jaramillo Arriba
4.92 out of 5 average rating, 38 reviews

Casita Caramelo

DavidRating, 5 stars16 months ago
A quiet apartment surrounded by a beautiful garden. The home was very clean, and we felt at home right away. Our host Pam was very welcoming to us. I cook and whatever I reached for, Pam had provided. No scratch teflon, a good set of knives and a sharpener, plenty of dishes and glassware, the list goes on. She was particularly considerate to our privacy (for example, by calling us when she’d have to be behind the house to refill a gas canister) but was always responsive when we’d reach out. And she’s a lovely friendly person too.
Guesthouse in Panamá
4.4 out of 5 average rating, 5 reviews

Mochila & Art Family House

Alba RosemarieRating, 5 stars77 months ago
Las personas súper atentas, nos dieron muchas recomendaciones para los traslados, y lugares para visitar, los desayunos muy ricos, recomendado.
Guest favorite
Guesthouse in Alto Boquete
4.84 out of 5 average rating, 73 reviews

Alojamiento Sinsonte

HelenaRating, 5 stars1 month ago
We had a lovely time and highly recommend staying here. We were traveling with our 4-month-old baby and Yadira and her husband were so helpful as well as generous about flexible checkin and check out times, which made such a difference. The apartment felt cozy and tidy, and had all the amenities one could need.
Guesthouse in Panamá

Mochila & Art Family House

Guest house rentals with a patio

Guesthouse in Playa Coronado
4.8 out of 5 average rating, 5 reviews

• Coronado Guesthouse Zuramaya •

AnhaRating, 5 stars2 months ago
This is a wonderful little garden casita just steps from the beach! Its location made for great morning walks. It’s tucked away on a side street but walking distance to a few really good restaurants. Janette was a wonderful host; so kind and helpful. I will definitely be back!
Guesthouse in Torio
4.83 out of 5 average rating, 6 reviews

Cozy cabin w/ Queen Bed & ensuite 10 mn from Beach

SereneRating, 5 stars16 months ago
Los Pinos is nestled among pine trees and palm trees as well as many others. Everything is well shaded for a comfortable experience. My cabina was clean, the bed was comfortable. This is a real bed and breakfast, I was treated to eggs cooked to order, served with “hojaldre” a puff pastry, an authentic specialty. The host Mike is personable and a wealth of information about the area
Guesthouse in Bocas del Toro
4.8 out of 5 average rating, 30 reviews

Studio with Pool Near Beaches in Bocas del Toro

MonyRating, 5 stars2 months ago
me gustó la tranquilidad no estaba en el centro pero si relativamente cerca lo que me pareció 👌 muy lindo el lugar coincidía con las fotos. sinceramente muy satisfecha con todo y Carolina siempre estuvo atenta.
Top guest favorite
Guesthouse in Pedasi
5 out of 5 average rating, 31 reviews

A Remote Paradise in nature - Ocean View

DennisRating, 5 stars3 months ago
Dennis was an EXCELLENT host !! From the moment we arrived, his purpose was for us to have a memorable experience ! We are seasoned traveler's, The price included wonderful breakfast every morning. he gave us all the information we requested, in a timely manner. When we come back, we will stay with him. Thank you Dennis and Juan. Our fair well dinner was FABULOUS !! We both highly recommend staying here. until we see you again our friend ! Daisy and Dennis Bush
Guesthouse in Torio
4.58 out of 5 average rating, 26 reviews

Olé #2 | Close the beach, restaurants, activities

MikeRating, 5 stars3 months ago
Thank you John, Anita and Team Olé! We had a fantastic time visiting Torio. The cabaña was clean, modern, with A/C and a beautiful semi-outdoor bathroom. The location is central to Torio town, with several restaurants and beach in walking distance. The cabaña is located next to the Olé TexMex restaurant and the food is incredible (we recommend the birria tacos). A special thanks to the team for the excellent customer service and recommendations. John and Anita were even kind enough to drive my partner and I to a local spot to visit the waterfalls that was harder to reach on foot. We 100% recommend visiting this gem of a town for anyone wanting to explore a different part of Veraguas, and Olé is a great place to stay! Thank you again!
Guest favorite
Guesthouse in Bocas del Toro
5 out of 5 average rating, 9 reviews

Toucan Bay Lodging & Holistic Services

TessaRating, 5 stars4 months ago
Our stay at Jen and Chris’s Airbnb was pure magic. From the moment we arrived, we were surrounded by breathtaking views and the kind of tranquility that only comes with being right on the water. The casita was thoughtfully designed, with a well-equipped kitchen that made cooking easy and enjoyable. Waking up to the sound of the waves and sipping coffee while watching birds flit through the trees was an absolute dream. The water access here is incredible; calm, clear, and perfect for swimming. We spent so much time in and out of the water, just soaking in the beauty of the place. The kids ran wild together from sunrise to sunset, fully immersed in nature, and we loved seeing them so free and happy. One of the highlights of our trip was the massage I received from Jen. I can confidently say it was one of the best massages of my life. It was intuitive and deeply relaxing. It was exactly what I didn’t even know I needed.
Superhost
Guesthouse in Rio Sereno
5 out of 5 average rating, 3 reviews

The Farmer’s Shack - Pure Nature

AmadorRating, 5 stars16 months ago
El espacio que rodea el alojamiento era tan hermoso y la propiedad en sí era muy acogedora. Todo el lugar perfecto para ir en pareja. La Sra Edisa y Silvia fueron muy comunicativas en todo momento. Las instrucciones fueron claras. El cuarto es ideal para un momento íntimo y desconectarse. Por ahora no hay internet para teletrabajar, por lo que puede desconectarse para relajarse. Es un excelente lugar para compartir en pareja. Me hubiera gustado quedarme a vivir jeje. Descansamos profundamente. El patio es amplio y cómoda. Todo muy limpio. Me gustaba salir a la terraza a ver el paisaje. Solamente estar en la casa te da paz. El terreno también es amplio pero empinado. Ambiente agradable. Fresco de día, frío en la noche. Silvia y Edisa siempre nos ayudaron y respondían de forma rápida. Recomendamos llegar de día para encontrar bien la ubicación. De noche puede ser confuso, pero pudimos llegar sin problemas con un auto 4x4. Es muy intenso el camino para un carro sedan.
Top guest favorite
Guesthouse in Alto Boquete
4.88 out of 5 average rating, 24 reviews

Bungalow Villa Castillo, Boquete.

AstridRating, 5 stars2 months ago
Excelente espacio, muy calmado y lindo. Los perros son la mejor parte.

Guest house rentals with a washer and dryer

Guest favorite
Guesthouse in Panamá
4.85 out of 5 average rating, 33 reviews

Casa de huésped privada en Ancón

MichaelRating, 5 stars6 days ago
Clean, quiet, friendly and a convenient location. My kinda place!
Top guest favorite
Guesthouse in Boquete District
4.96 out of 5 average rating, 23 reviews

Casa Tropical Boquete, Duplex#1 2R /2BR

VickieRating, 5 stars1 week ago
The setting at Casa Tropical is very beautiful. The location is great ... easy drive to town. Jhayat and Abdul were great hosts and very responsive to all requests.
Superhost
Guesthouse in Playa Venao

Modern Casita just a short walk to the beach

LuisRating, 5 stars16 months ago
La persona que nos atendio fue Esteban, increible su atencion y con muy buena comunicacion, la casa estaba excelente y muy bien posicionada
Superhost
Guesthouse in La Chorrera
5 out of 5 average rating, 3 reviews

Rincón encantado en La Chorrera

AjotaRating, 5 stars5 months ago
Casita acogedora tipo apartamento estudio dentro de una propiedad principal. La sala comedor tiene pisos de baldosas de terracota con muebles cómodos y funcionales. Sus áreas están iluminadas por luz natural y decoradas con plantas. Se encuentra en una zona muy tranquila, fuera del centro.
Superhost
Guesthouse in Panamá
New place to stay

The Black Studio near airport & city

HansRating, 5 stars3 weeks ago
Todo muy bien. Excelente lugar. Anfitriona increíble. 100 % recomendado
Guest favorite
Guesthouse in Los Naranjos
4.71 out of 5 average rating, 70 reviews

Cabañas de Alicia 1

VeroniqueRating, 5 stars3 months ago
Clean and nice place, fits described bedrooms. Ezequiel was very friendly and helpful. Well placed, a bit further from Boquete but still close and close to the Lost falls that was a great hike. Washington machine was not in the unit but easy to wash clothes asking Ezequiel. Beds were comfortable.
Guest favorite
Guesthouse in David
5 out of 5 average rating, 8 reviews

Acogedor, tranquilo y excelente ubicación!

BlaneRating, 5 stars13 months ago
Staying here was an outstanding experience in more ways than one. This is a good location for exploring other parts of Panama. Look up "Villa del Carmen, David, Panama" on Google Maps to get an idea. Tranquil is a good way to describe the area also. Apt. Isn't big, but is plenty good for 1 or 2 people. Kitchen & sitting areas are outside, with everything you need. If it gets too hot in the afternoon, just take a little siesta inside & you'll be fine. Very relaxing! Lina was an excellent host, & I had the pleasure of spending time with her. The apt. itself is behind the home of a nice, sweet, kind, helpful, generous woman named Amarilis. Get to know her! Amarilis turned a good experience into a great one! We had many good conversations (using Google Translate), she was patient with my lousy Spanish & I enjoyed her company very much. She & Lina helped make my decision to move to Panama an easy one, & I look forward to seeing them both again. Wish I could write more! I highly recommend!
Top guest favorite
Guesthouse in San José
4.96 out of 5 average rating, 28 reviews

Guesthouse in Punta Barco Resort

BirgitRating, 5 stars1 month ago
Ein ganz herzliches Dankeschön für die mega Gastfreundschaft! Wir haben uns super wohl gefühlt und planen bereits einen weiteren Besuch :-) Mit eurer Hilfe und Tipps war es ein toller Urlaub. Die Familie samt Hunde sind einfach alle so liebenswert! Der Pool ist groß und sauber, die Terrasse grenzt fast an 'Dschungel' mit Geiern im Baum, Papageien und Besuch vom großen Leguan gab es auch, nur Faultier Dieter ließ sich nicht blicken. Das Meer mit Privatzugang war soooo warm, ein Traum! Auch der große Pool dort ist auch sauber und gepflegt. 100% Weiterempfehlung ♥

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