Guesthouse vacation rentals in Panama

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Top-rated guesthouse rentals in Panama

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Los Naranjos

4.92 out of 5 average rating, 225 reviews

Sunshine Cottage at Finca Katrina

Sunshine Cottage is a little cottage in the back garden of Finca Katrina. It is set on a hill with views of Palo Alto and Jaramillo with a coffee plantation in the foreground. There is a full (double) bed, room to hang your clothes and to store your belongings. You have a small fridge, toaster oven, sink, coffee maker, and cupboard space for food, but no stove top. If you are looking for more bedrooms, there are additional units on Finca Katrina that compliment Sunshine Cottage. Send us a note!

Guest favorite

Guesthouse in Panamá

4.76 out of 5 average rating, 240 reviews

Garden Cottage in city center

Cozy Private Cottage in Panama City Enjoy a comfortable stay in this charming garden cottage located in a central area of Panama City. With a private entrance, garden, and outdoor barbecue area, you'll have everything you need for a perfect getaway. The property features WiFi, smart TV, air conditioning, a double bed, and a sofa bed in the living room, as well as a fully equipped kitchen and bathroom. It also includes a washer and dryer for your convenience Perfect for an unforgettable escape

Top guest favorite

Guesthouse in El Valle de Antón

5 out of 5 average rating, 28 reviews

The Retreat in El Valle - Garden House

Welcome to your serene retreat in El Valle, Panama! Nestled amid lush nature, our two-bedroom casitas offer a peaceful escape with breathtaking views, exotic wildlife, and flora. Each casita features a queen bed, choice of king or twin beds in the second room, a small fridge, coffee station, Wi-Fi, and large terrace. Enjoy the shared pool, meditation and healing sessions by appointment, and explore world-class hiking nearby. Just a short walk to restaurants and El Valle’s famous artisan market!

Top guest favorite

Guesthouse in Gamboa

4.95 out of 5 average rating, 73 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Top guest favorite

Guesthouse in Torio

4.91 out of 5 average rating, 136 reviews

Torio guesthouse with panoramic view

Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.

Top guest favorite

Guesthouse in David

5 out of 5 average rating, 64 reviews

Pool House with Shared Pool Access

Pool House is a fully private space on a shared gated property. NOTE: We, the owners of the property, live in the Main House full time. If you have questions/need recommendations, we are available! Shared spaces on property: Pool, front yard, back walk way Local suburb, with bus and taxi access into town and plenty of parking if you choose to drive. 45 minutes from Boquete, 1 hour from Boca Chica and 2 hours and 1 hour boat ride to Bocas Del Toro, this location is a day-tripper's dream!

Guest favorite

Guesthouse in La Ermita de San Carlos

4.97 out of 5 average rating, 124 reviews

Rural+comfy: AC, WiFi, hot water, pool, private

The Sky Cabin is part of 5 cabins “A Piece of Paradise” With registration in the Panamanian Tourism Authority Bureau. ✸ Ideal for a couple or a single person ✸ Outdoor dining area and kitchen ✸ Spacious terrace with a hammock ✸ Very quiet neighborhood ✸ Private and public transportation available, just ask and we will help you ✸ 7-10 minutes, by car, from Playa La Ermita and 10 minutes from Playa El Palmar (great spot for surfing) ✸ Breakfast for an additional $7.00, for each guest.

Guest favorite

Guesthouse in Bocas del Toro

4.91 out of 5 average rating, 56 reviews

The Boat House in Big Bight

Come relax in this peaceful over the water ECO bungalow on Isla Colon, on a coral reef 15 minutes away from town BY BOAT ONLY.. See lots of stars in the sky, tons of sea life & stunning sunsets from your balcony! Enjoy Starfish Beach, just a 5 minute boat ride away. Red Frog Beach, Playa Bluff, Zapatillas, & much more while you're here in Bocas Del Toro! (Kitchen is provided with basic cooking essentials & bathroom with basic personal items).

Top guest favorite

Guesthouse in El Valle de Antón

4.99 out of 5 average rating, 94 reviews

Spacious Casita with Bamboo View

Walk to the artisan mercado, restaurants and Cerro Cara Iguana trailhead. High ceilings, new fridge, washer and dryer. Private hammock patio for an afternoon nap. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. Living room has a small smart TV for your USB or media accounts. Internet and a small workspace available. * Non smoking property, inside and out

Guest favorite

Guesthouse in Mariato

4.96 out of 5 average rating, 81 reviews

Beachfront/Private Full floor Studio in Guesthouse

1km beautiful sandy beach. STARLINK internet. Peace & Quiet. 4 wheel drive car is not required. Soft rhythmic sound of the waves. Every week; new birds, turtles nesting, dolphins, whales or monkeys. See the stars without light pollution. Ocean is perfect for swimming and sometimes body-boarding. Swim in our pool anytime you like. If you surf, we have walking or driving access to famous surfing beach, Morrillo.

Guest favorite

Guesthouse in Panama City

4.9 out of 5 average rating, 210 reviews

#1 Personal Studio 9 km International Airport

Independent Mini Studio, It has A/C, with its bathroom. Located near Tocumen International Airport, 10 to 13 minutes by car. The Studio is close to 2 Shopping Centers, Metromall and Los Pueblos. The residential area is safe for walking, organized and clean streets. We have the Cerro Viento Metro station outside in Metromall. Space to prepare light meals.

Superhost

Guesthouse in Panama City

4.84 out of 5 average rating, 74 reviews

A small apartment-style annex

The place is close to Tocumen airport (15 minutes), has WiFi, cable service, Netflix and has shops and supermarkets around it, very close to nature, it is a quiet and cozy place. You can also take a taxi or Uber to get to the Panama Metro (10 minutes). We have round-trip transportation service to Tocumen Airport, for an additional cost.