Apartment vacation rentals in Panama City

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Top-rated apartment rentals in Panama City

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Top guest favorite

A modern living space features an open kitchen with wooden cabinetry and a dining area. A curved gray sofa is complemented by yellow pillows, positioned next to a round coffee table. Natural light streams through blinds, illuminating the minimalist decor.

Apartment in Panamá

5 out of 5 average rating, 79 reviews

New apartment on 50th Street

Enjoy a stylish experience at this centrally-located place. Direct access to bus lines and the Metro. Close to tourist sites and steps away from a variety of restaurants, grocery store, nightlife, casinos and blocks from the coastal strip, Iglesia del Carmen, and Parque Urraca. The old town is just minutes away by Uber. Close to shopping area. Soho Mall, Multi Plaza Mall, and Albrook Mall. Relaxing swimming pool for adults and children. Bar and restaurant, co-working, gym. You'll have a great time.

Top guest favorite

A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.

Apartment in Punta Paitilla

5 out of 5 average rating, 32 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Superhost

A cozy living area features a comfortable blue sofa against an original brick wall, complemented by a round mirror. A small kitchen area with white cabinetry and modern appliances is visible. A decorative coffee table and elegant chairs complete the inviting space.

Apartment in Panamá

4.81 out of 5 average rating, 146 reviews

The Penthouse Annex

Inspired by Panama's rich history with France and located in one of the oldest watch towers in Panama, this chic apartment combines original features of this historically important building with the elegance and style of Europe. Perfectly situated to indulge in the restaurants, cafes, museums and boutique stores of Casco Viejo, and equipped with everything you expect from a home-from-home base, the annex is the perfect combination of comfort and style for couples and small groups of friends.

Top guest favorite

A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.

Apartment in Panamá

4.98 out of 5 average rating, 142 reviews

Escape to the Heart of Casco with a Private Balcony

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Top guest favorite

An expansive infinity pool reflects the skyline of Panama City and the nearby bay. Lounge chairs are arranged neatly along the poolside, allowing for relaxation while enjoying the panoramic views of the surrounding area.

Apartment in Panama City

4.98 out of 5 average rating, 46 reviews

Impressive with ocean and Panama city views

Experience a unique, modern apartment with its own style, where every sunrise and sunset becomes a show. Enjoy breathtaking views of Panama City, the bay, and the Old Town from the comfort of your accommodation. Location Unbeatable Located just 5 minutes from the charming Old Town and the famous seafood market, and 10 minutes from the banking area. In addition, you will have a metro station and several bus stops just a few steps from the building

Guest favorite

An inviting pool area features a serene swimming pool surrounded by lounge chairs. The contemporary building's façade is illuminated, showcasing expansive glass windows and greenery, creating a welcoming ambiance for relaxation and leisure.

Apartment in Panamá

5 out of 5 average rating, 12 reviews

Stylish Casco Antiguo Apt • Pool & Parking

Stay in a stylish modern apartment just steps from Panama City’s historic Casco Viejo and the scenic Cinta Costera Recently decorated with a contemporary design, it’s perfect for relaxing or working remotely with fast WiFi. Guests enjoy access to a rooftop with panoramic views and pool, a coworking space, and private parking. Surrounded by top restaurants, bars, shops, and major attractions, it’s the ideal base to discover the magic of Panama.

Top guest favorite

A welcoming living area features modern furnishings and vibrant artwork. A round wooden coffee table is accompanied by a cozy sofa and armchairs. Natural light pours in from large glass doors leading to a balcony, while a plant adds a touch of greenery.

Apartment in Panamá

4.95 out of 5 average rating, 116 reviews

Luxury apartment in Panama, ocean view

Located in San Francisco, one of Panama's exclusive areas par excellence, where gastronomy, history, modernity, and entertainment magically combine. Wonderful location near must-see destinations, gym, swimming pool, co-working, pet spa, and terrace. Parking is charged. Modern and functional, this apartment features a queen-size bed, fully-equipped kitchen, Wi-Fi, TV, a spectacular balcony with ocean views, laundry center, and sofa bed.

Top guest favorite

An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.

Apartment in Panamá

4.97 out of 5 average rating, 113 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Top guest favorite

A cozy living area features a light-colored sofa facing a wall-mounted television. A round table is set in front, and woven placemats add texture. Large windows showcase city views and provide natural light, while a bedroom is visible in the background, showcasing a spacious bed.

Apartment in Panamá

4.98 out of 5 average rating, 107 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favorite

A private terrace features a jacuzzi surrounded by lush greenery against an exposed stone wall. Wooden decking creates a warm ambiance, complemented by two lounge chairs designed for relaxation, offering an inviting outdoor space for guests.

Apartment in Panama City

4.9 out of 5 average rating, 148 reviews

Jacuzzi in colonial ruins in beautiful apartment

Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Top guest favorite

A spacious terrace features modern lounge chairs facing an infinity pool that blends with the ocean horizon. Clear blue skies and serene water create a tranquil setting. The surrounding palm trees add a touch of greenery to the area, enhancing the overall views.

Apartment in Panamá

4.99 out of 5 average rating, 103 reviews

Sky Lounge/ APT 1 BR-vista al Mar/Pool bar & GYM

Moderno apartamento de lujo en la Cinta Costera, ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño privado, cocina y electrodomésticos. Diseño elegante con seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Ubicación privilegiada cerca de supermercados y excelente oferta gastronómica en Ciudad de Panamá. PANAMA

Guest favorite

The studio apartment features a historic stone wall contrasted by modern furnishings, including a queen-size bed and sofa-bed. A dining table and working desk are present, with warm wood flooring enhancing the spacious feel. Natural light enters through large windows, illuminating the inviting space.

Apartment in Panamá

4.93 out of 5 average rating, 350 reviews

Mola Studio | By Paradox

PRIVATE APARTMENT IN PANAMA CITY, CLOSE TO CASCO VIEJO. If you're looking to get submerged into real Panama and live among the real locals. This is the right place to be. For More Info or visual content, follow us on IG as Paradox Experience and visit our Virtual Showcase with the link in our IG BIO. More than a regular stay, we are an experience.