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Vacation rentals in Panama City

Find and book unique accommodations on Airbnb

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Popular amenities for Panama City vacation rentals

Stay near Panama City's top sights

Albrook Mall132 locals recommend
Multiplaza Panama147 locals recommend
Causeway Amador67 locals recommend
AltaPlaza Mall38 locals recommend
Atlapa Convention Center15 locals recommend
Sheraton Grand Panama5 locals recommend

Other great vacation rentals in Panama City

Guest favorite

Loft in Panamá

4.88 out of 5 average rating, 82 reviews

Corcho rooms b&b - queen rom with a balcony

Jan 2 – 9

R1,895 ZAR per night
Guest favorite

Apartment in Panamá

4.96 out of 5 average rating, 28 reviews

Stunning Sea View apt at city center

Dec 14 – 21

R1,937 ZAR per night
Guest favorite

Condo in Panamá

4.93 out of 5 average rating, 71 reviews

CASA SAENA "B"- Designer, Casco Viejo Panama

Oct 22 – 29

R2,763 ZAR per night
Guest favorite

Condo in Panamá

5.0 out of 5 average rating, 5 reviews

Nice apartment in Panamá City. Panamá

Feb 24 – Mar 3

R3,127 ZAR per night
Guest favorite

Cottage in Panamá

4.95 out of 5 average rating, 20 reviews

Modern House in Altos de Cerro Azul with 2 rooms

May 5 – 12

R2,302 ZAR per night
Guest favorite

Apartment in Panamá

4.97 out of 5 average rating, 60 reviews

Superb Apartment In The Center Of Panama City

Jun 18 – 25

R1,481 ZAR per night
Guest favorite

Apartment in Panama City

5.0 out of 5 average rating, 15 reviews

BEST VIEW in Old Town, Panama (Casco Viejo)

Jun 28 – Jul 5

R2,061 ZAR per night
Guest favorite

Home in Panamá

5.0 out of 5 average rating, 5 reviews

Unique 4 room house - direct access to the beach

Oct 8 – 15

R9,479 ZAR per night

Quick stats about vacation rentals in Panama City

  • Total rentals

    4.1K properties

  • Rentals with a pool

    2.2K properties have a pool

  • Pet-friendly rentals

    1.3K properties allow pets

  • Family-friendly rentals

    1.4K properties are a good fit for families

  • Total number of reviews

    77K reviews

  • Nightly prices starting at

    R191 ZAR before taxes and fees

Frequently Asked Questions

  • How is the weather in Panama City?

    Panama City has a tropical climate with high temperatures throughout the year, usually ranging from 75°F to 88°F (24°C to 31°C). Rainy season occurs between May and December, while the dry season extends from January to April.

  • What are some of the best things to do in Panama City?

    Popular activities in Panama City include exploring the historic Casco Viejo district, visiting the Panama Canal Museum, and strolling along the Cinta Costera. Birdwatching in the Metropolitan Natural Park and shopping in the Mercado de Mariscos are also often recommended.

  • What is the best time of year to visit Panama City?

    The most frequented time to visit Panama City is between January and April. This period coincides with Panama's dry season, which enables more comfortable exploration of the city's many attractions. During this time, the vibrant and lively Carnival of Panama, typically held in February, draws a sizable crowd.

  • What are the best places to stay in Panama City?

    Casco Viejo, the city's historic district, is a popular area to stay in Panama City due to its colonial architecture and range of dining options. The modern neighborhood of Punta Paitilla is often recommended for its skyscrapers and shopping centers, while Costa del Este appeals to those seeking a quieter, residential ambiance.

  • What are the best places to visit in Panama City?

    Many visitors to Panama City enjoy the historic district of Casco Viejo, the Panama Canal, and the Metropolitan Natural Park. Other frequently suggested places include the Amador Causeway for its stunning views, and the Biomuseo for its distinct architecture and exhibits on biodiversity.

  • What are some hiking trails in Panama City?

    The Metropolitan Natural Park, located within Panama City, has several hiking trails, such as the Mono Titi Road and the Los Momotides trail. Just outside the city, you can explore the trails of the Soberania National Park, including the Pipeline Road, known for its diverse birdlife.

  • What are some family activities to do in Panama City?

    Families in Panama City often enjoy a visit to the Biomuseo, a museum renowned for its exhibits on biodiversity. The Panama Canal, particularly the Miraflores Locks, provides an educational experience. The Metropolitan Natural Park and Summit Botanical Gardens and Zoo are also popular destinations for families.

  • What are some of the best day trip ideas in Panama City?

    A day trip to the Panama Canal, specifically the Miraflores Locks, is frequently suggested. The beautiful Pearl Islands are also accessible for a day trip from the city. Within the city, exploring the historic district of Casco Viejo, or the biodiversity of the Metropolitan Natural Park, make for enjoyable day trips.

  • Are there family-friendly condo rentals in Panama City?

    Panama City has more than 280 family-friendly condo rentals. Amenities on the property may include high chairs, travel cribs, or strollers.

  • How much does it cost to stay in house rentals in Panama City?

    Experience the best of Panama City with our house rentals, starting at about $10 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panama City