Family-friendly vacation rentals in Santee

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Santee

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in San Diego

4.97 out of 5 average rating, 506 reviews

Central & Serene Secret Garden Guesthouse

My cozy & stylish Garden Guesthouse features colorful decor that gives a fun, relaxed vibe. Relax in style inside or outside in my peaceful garden w a cup of coffee, or glass of wine. I love to say a hi to my guests yet your privacy is #1. Reach me via Airbnb app if I can help! Kensington is a central, 1920’s historic neighborhood w shops & great local eateries. Close to downtown, Gaslamp, Zoo, airport, beaches, Balboa Park. Bus stop, & trolley nearby. Reserved off street parking space too!

Oct 16 – 23

R2,794 ZAR per night

Guest favorite

Guesthouse in La Mesa

4.92 out of 5 average rating, 205 reviews

Fig Tree Bungalow

Enjoy your stay in San Diego in this newly renovated guesthouse. Centrally located about a mile from Hwy 8, Hwy 125, and the Grossmont Trolley Station & Transit Center. Only a 15-20 minute drive to downtown, the airport, the beaches, and most of San Diego's other popular tourist attractions. This cozy, two-story, detached unit is located behind my home, and has its own private entrance and partitioned yard for your enjoyment. There's plenty of street parking directly in front of the house.

Jun 22 – 29

R2,421 ZAR per night

Guest favorite

Guesthouse in La Mesa

4.93 out of 5 average rating, 136 reviews

Granny Flat with Bedroom/Bathroom/Kitchen

My place is family friendly, close to comic con, , restaurants and dining, , the beach, , family-friendly activities , public transportation (trolley). You’ll love my place because of the peace and quiet. It's very quiet and private. PLEASE DO NOT BOOK IF YOU ARE PLANNING ON PARTYING. THIS IS NOT APPROPRIATE FOR MORE THAN 2 PEOPLE. There is a private entrance that you may use once you meet us.. We like to meet all our guests first and then you may come and go as needed. NO SMOKING NO PETS

Mar 17 – 24

R2,112 ZAR per night

Guest favorite

Guesthouse in San Diego

4.97 out of 5 average rating, 292 reviews

Private Guest House with a View

A charming, detached guest house located centrally in San Diego, Ca. Guest house is located on a hill with views of the canyon. Get full access to your own kitchen with coffee & tea amenities. Wifi access. Smart TV access to Netflix, Prime Video, Disney+, Hulu, etc.. Comfortable queen bed with a full size sofa pullout bed that can accommodate up to 4 guests. Clean and spacious backyard that you can relax and unwind in. 80’ leveled driveway 12’ wide is big enough to accommodate any RV.

Aug 6 – 13

R2,910 ZAR per night

Guest favorite

Yurt in El Cajon

4.98 out of 5 average rating, 302 reviews

Glamping @ Eden East

Are you looking for the perfect most cozy space to chill with your favorite person or just for some time alone? Cozy Yome with private deck and spacious pool area. Not just a place to stay, but a peaceful retreat. Seasonal creek when it's raining & hot tub, hot shower and flush toilet in plant filled outdoor bathroom. Cozy warm fluffy sheets as well as space heater inside. By reserving, we are assuming you've read entire ad and agree to rules. We are located outside of the city of El Cajon.

Nov 29 – Dec 6

R2,260 ZAR per night

Superhost

Guest suite in La Mesa

4.94 out of 5 average rating, 162 reviews

Hacienda de Las Campanas

Stay in classic, historic California Hacienda style! A complete, self-contained apartment--your casita--within our beautiful, historic Monterey Spanish Revival hacienda home, situated on a half acre. The apartment has a separate, private entrance and includes a sunlit living/dining room opening on to a large swimming pool; a small kitchenette; and a private bedroom and bathroom down your own hallway. The suite is tastefully furnished consistently with the historic Spanish architecture.

Feb 25 – Mar 4

R3,456 ZAR per night

Guest favorite

Apartment in San Diego

4.98 out of 5 average rating, 401 reviews

Lovely spacious upstairs studio with private entry

You’ll love our place as its spacious, quiet, private, comfortable in a residential neighborhood. The king-size bed is extremely comfortable and we have big relaxing patio chairs on our large balcony overlooking a beautiful landscaped garden. We are centrally located to most all of San Diego's attractions and close to freeways. The famous Gaslamp, Zoo, downtown and beaches are all within 13 to 20 minute drive. The kitchen is stocked with goodies, coffee and an assortment of teas.

Mar 14 – 21

R1,920 ZAR per night

Guest favorite

Guesthouse in El Cajon

4.98 out of 5 average rating, 190 reviews

Fletcher Hills - modern 1 BR.Easy, no step access.

** 48 hours between check-ins. Thorough cleaning and sanitizing.. Four night minimum stay. Dogs ONLY are welcomed on a case by case basis. They must be house trained and are not permitted on any furniture. If you instant book, you must contact me about your pet within 24 hours. Smoking is permitted in the outside areas - patio, gazebo, yard. Easy freeway access helps any commute to downtown and area attractions. Having your own vehicle is the best way to get around..

Apr 24 – May 1

R2,259 ZAR per night

Guest favorite

Cottage in La Mesa

4.97 out of 5 average rating, 277 reviews

La Mesa House On a Hill With Mountain Views!

SUNRISE PERCH - A standalone guest house, perfect spot for your San Diego stay! Enjoy inspiring sunrise views from the deck or relax indoors with super fast WiFi and a 43" TV. Enjoy a full kitchen! The king bed is super comfy and the bathroom is stocked. The space is only for those looking for quiet. No partying/loud socializing. Families welcome! Located 20 min from downtown San Diego and 25 min from the nearest beach (Ocean Beach).

Aug 19 – 26

R3,039 ZAR per night

Guest favorite

Guest suite in La Mesa

4.9 out of 5 average rating, 172 reviews

Charming Suite in Historic Home

Stay in your own apartment on the second level of our 1907 Landmark Historic home in the Village of La Mesa. Escape to the backyard retreat with a private swimming pool and spa, barbecue grill, and outside dining. Walk to shops and restaurants, and ride the trolley to downtown San Diego or Tijuana. There is convenient free parking on the street and easy drive to mountain, desert, and ocean adventures and major tourist attractions.

Oct 8 – 15

R2,609 ZAR per night

Guest favorite

Guesthouse in San Diego

4.94 out of 5 average rating, 333 reviews

The BEST NEST Clean, peaceful, private, affordable

This lovely private & separate unit is comfortable, clean and convenient. Your completely private suite is accessible via your own entrance. Minutes from major attractions, away from the hustle and bustle. Newly remodeled living room and FULL kitchen. Located in a nice neighborhood just off major freeways. Sip your morning coffee, relax and enjoy the gorgeous San Diego weather in the quaint, outdoor garden.

Feb 20 – 27

R2,131 ZAR per night

Guest favorite

Guest suite in San Diego

4.97 out of 5 average rating, 299 reviews

Comfy, cozy updated Guest Home (patio, views, a/c)

Retreat to our peaceful guest home, only a short 20-minute drive from lively beaches. Relax in comfortable spaces filled with sunlight, perfect for enjoying your morning coffee or evening wine as you watch the sunset. After exploring the nearby shores and indulging in endless adventures, come back to unwind on the secluded patio or gaze at the stars while sipping cocktails.

Oct 5 – 12

R2,167 ZAR per night