Lake house vacation rentals in Santee

Find and book unique lake houses on Airbnb

Top-rated lake house rentals in Santee

Guests agree: these lake houses are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Spring Valley

4.88 out of 5 average rating, 41 reviews

SD Lux Oasis: Theatre, Spa, 14Beds, AC, Sleeps 20+

SEND US MESSAGE FOR SPECIAL OFFER! Highlights: ⭐️14 beds/6bed/3.5bath ⭐️ Pickleball Court & Golf Course: Play a fun match on your private, stylish court! ⭐️Theater Room: Cozy up for a movie night w/ premium sound and luxurious seating. ⭐️Classy Get-Ready Station: Perfect for preparing for events, complete with ample lighting and mirrors. ⭐️Sparkling Pool & Spa: Relax and unwind in the sun or under the stars. We have one ring camera outside the front door & you’ll be 18 min away from to downtown!

Top guest favorite

Home in Oceanside

4.96 out of 5 average rating, 95 reviews

Close to Legoland & Beaches with Pool/Spa & Views!

Spectacular views of Calavera Lake Preserve w/miles of scenic hiking trails directly out the back gate. Take a swim (heating optional) in lagoon-style pool, or spa in the private, resort-like backyard featuring fire pits, BBQ & cozy gathering areas. Conveniently located mins from Legoland, Frontwave Arena, Beaches, Eateries, Breweries, Wineries, Oceanside Pier & Harbor. Only 30(+) mins to World Famous San Diego Zoo, Balboa Park, Wild Animal Safari Park, SeaWorld, Old Town & Downtown San Diego.

Top guest favorite

Home in Mission Beach

4.99 out of 5 average rating, 181 reviews

Steps To Beach! Family Friendly-Remote Office-Fire

House with Full-Size Car Garage, AC, private gas camping-style Fire in the Yard, 2 Patios, 2 Indoor Gas Fireplaces, Grill, & Laundry. 3 Bedrooms, 2 are primary with bathrooms, one with fireplace & kitchenette. Fully equipped Kitchen with outdoor Grill, just off the Dining area. Office Space plus fast 3 hub WiFi-6 coverage everywhere. 50 steps from the Beach or the Bay. Short ocean walk to PB with tons of restaurants & boutiques. Yelp lists 86 restaurants with 4-star+ reviews within easy walk.

Top guest favorite

Home in Talmadge

4.97 out of 5 average rating, 94 reviews

Cozy+Spacious+Family-Friendly~by all attractions!

Enjoy the comfort of our newly renovated, spacious 3-bedroom (4bed)/2-bath getaway, which features a large private yard, hot tub, and fully equipped kitchen, bathrooms, and laundry room! Unbeatable location with easy freeway access and minutes away from bars, restaurants, shops, and the vibrant SDSU campus. SD airport and downtown attractions are only 15-20 minutes away. Perfect for a large family, big group of friends, or cozy home base while exploring everything San Diego has to offer!

Superhost

Home in La Mesa

4.9 out of 5 average rating, 73 reviews

Casita DolceVita

Casita DOLCEVITA is a totally independent, lovely, and cozy apartment, with direct and exclusive access and use to the patio, hot tube, and garden. The unit is located on the 1st floor of a hillside house that has another independent unit on the 2nd floor, not included in the booking. The property is just 15 min from San Diego and the beaches, located in a beautiful characteristic little town, La Mesa Village and surrounded by a garden full of flowers and birds like hummingbirds and parrots.

Top guest favorite

Home in Lakeside

5 out of 5 average rating, 26 reviews

The Birdhouse SD: King Beds, Pool, Spa & Firepit!

Welcome to The Birdhouse SD, a pet-friendly historic cottage tucked in the scenic foothills of San Diego! This charming retreat offers everything you desire in a vacation getaway: luxurious velvet and leather interiors, a private pool and spa, a shaded palapa, chef’s kitchen, game room, and outdoor fire pit! Lounge poolside with the calming sounds of the waterfall. Nestled next to the beautiful Lindo Park, enjoy walking trails, fishing, and a skatepark. Perfect for relaxing and recharging!

Guest favorite

Home in Scripps Miramar Ranch

4.97 out of 5 average rating, 115 reviews

Luxurious Home w/Hot Tub & Pool + Water Slide

This freshly painted (2025) tropical oasis is located in the Waterford Scripps Ranch community. The house has a large & inviting pool, a terrific slide for kids, a hot tub & a builtin BBQ. It's a perfect place for a family to relax & enjoy all that San Diego has to offer. It's a couple of miles from the lake w/ beautiful views, jogging, biking, canoeing, and more. It's centrally located in San Diego, <30 minutes from most things including downtown, the beaches, the Wild Animal Park & more.

Superhost

Home in Ramona

4.83 out of 5 average rating, 183 reviews

ENJOY A REAL FARM EXPERIENCE!

EXPERIENCE FARM LIFE! RESTORED OLD 3-BEDROOM 2-BATH FARMHOUSE ON 20 ACRES OF COWS, GOATS, CHICKENS, DUCKS! FEED THEM IF YOU LIKE. COLLECT EGGS FROM THE COOP AND PREPARE THEM IN THE OLD KITCHEN, RING THE TRIANGLE BELL AND DINE IN THE PASTURE! Stocked for breakfast, and since our farm is near town, a short drive for more groceries. Wi-fi. Netflix. Stay for a night or stay a month! Ramona offers antiquing, 3 excellent golf courses, 30 wineries, hiking, horseback riding, birdwatching.

Superhost

Home in San Diego

4.78 out of 5 average rating, 139 reviews

Dream Home Away From Home - Huge Common Area!

Bring the whole family to this spacious 1904 square foot home with TWO king sized bed suites and three full bathrooms! Located centrally in San Diego, this is a perfect place to stay for those seeking an experience close to the beach and mountains and anywhere in San Diego you'd like to visit. The house is a short drive away from the zoo, Sea World, Animal Park, beaches, parks, downtown, trails, Balboa park, the Midway museum, Coronado, Torrey Pines, La Jolla Cove, and much more!

Guest favorite

Home in Lakeside

5 out of 5 average rating, 22 reviews

San Diego Lake home 4 Bd/Bath/Pool/Putting/Hot tub

This spacious four bedroom home is outfitted in beautiful modern decor. Also, a heated pool, hot tub, putting green and backyard with grill will provide a great space for your family vacation. 20 miles from Downtown San Diego! 20 miles from Balboa Park and the Zoo! 24 miles from the San Diego Airport! 26 miles from Mission Beach/Pacific Beach! 30 miles to the Mexico border crossing! 10 minute drive to Barona Casino! 6 minute drive to Lake Jennings! Book with us today! 🏡🏡

Guest favorite

Home in Scripps Miramar Ranch

4.91 out of 5 average rating, 74 reviews

20% OFF- Newly updated guesthome for families

Newly updated peaceful and convenient guesthome in Scripps Ranch. With a private dining room, a fully equipped private kitchen, two cozy bedrooms with desks, and a private bathroom. With central AC and 500Mbp WIFI. 1 minute's driving to a plaza with a supermarket, bank, Starbucks, and restaurants. 5 minutes’ drive to Lake Miramar. Perfect location for exploring UCSD, LaJolla Shores, San Diego Zoo, Sea World, Legoland, Balboa Park, and many other attractions in San Diego.

Guest favorite

Home in Poway

4.97 out of 5 average rating, 34 reviews

Ridgeview Oasis | Free Parking, Laundry, Grill

Welcome to Ridgeview Oasis! This tranquil haven offers a serene escape with a private trail leading to Lake Poway, perfect for nature enthusiasts. Embrace the tranquility of this safe area, conveniently located within 30 minutes of San Diego’s vibrant tourist spots. Indulge in a fully renovated space with brand-new amenities, ensuring comfort and luxury. Experience a harmonious blend of relaxation, nature, and accessibility at Ridgeview Oasis.