Lake house vacation rentals in Santee

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Top-rated lake house rentals in Santee

Guests agree: these lake houses are highly rated for location, cleanliness, and more.

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Superhost

Home in Spring Valley

4.82 out of 5 average rating, 49 reviews

SD Lux Oasis: Theatre, Spa, 14Beds, AC, Sleeps 20+

SEND US MESSAGE FOR SPECIAL OFFER! Highlights: ⭐️14 beds/6bed/3.5bath ⭐️ Pickleball Court & Golf Course: Play a fun match on your private, stylish court! ⭐️Theater Room: Cozy up for a movie night w/ premium sound and luxurious seating. ⭐️Classy Get-Ready Station: Perfect for preparing for events, complete with ample lighting and mirrors. ⭐️Sparkling Pool & Spa: Relax and unwind in the sun or under the stars. We have one ring camera outside the front door & you’ll be 18 min away from to downtown!

Top guest favorite

Home in Mission Beach

4.99 out of 5 average rating, 191 reviews

Steps To Beach! Family Friendly-Remote Office-Fire

House with Full-Size Car Garage, AC, private gas camping-style Fire in the Yard, 2 Patios, 2 Indoor Gas Fireplaces, Grill, & Laundry. 3 Bedrooms, 2 are primary with bathrooms, one with fireplace & kitchenette. Fully equipped Kitchen with outdoor Grill, just off the Dining area. Office Space plus fast 3 hub WiFi-6 coverage everywhere. 50 steps from the Beach or the Bay. Short ocean walk to PB with tons of restaurants & boutiques. Yelp lists 86 restaurants with 4-star+ reviews within easy walk.

Top guest favorite

Home in Talmadge

4.97 out of 5 average rating, 101 reviews

Cozy+Spacious+Family-Friendly~by all attractions!

Enjoy the comfort of our newly renovated, spacious 3-bedroom (4bed)/2-bath getaway, which features a large private yard, hot tub, and fully equipped kitchen, bathrooms, and laundry room! Unbeatable location with easy freeway access and minutes away from bars, restaurants, shops, and the vibrant SDSU campus. SD airport and downtown attractions are only 15-20 minutes away. Perfect for a large family, big group of friends, or cozy home base while exploring everything San Diego has to offer!

Superhost

Home in La Mesa

4.91 out of 5 average rating, 74 reviews

Casita DolceVita

Casita DOLCEVITA is a totally independent, lovely, and cozy apartment, with direct and exclusive access and use to the patio, hot tube, and garden. The unit is located on the 1st floor of a hillside house that has another independent unit on the 2nd floor, not included in the booking. The property is just 15 min from San Diego and the beaches, located in a beautiful characteristic little town, La Mesa Village and surrounded by a garden full of flowers and birds like hummingbirds and parrots.

Superhost

Home in Pacific Beach

5 out of 5 average rating, 3 reviews

One block to Bay | Firepit, AC & Putting Green

Welcome to your coastal escape—just one block from the calm shores of Mission Bay and a short stroll to the waves of Mission Beach! This fully renovated, thoughtfully designed 4-bedroom, 3-bathroom home features a private putting green, firepit, BBQ, A/C, and free parking—perfect for families, friend groups, and travelers seeking a luxurious yet laid-back San Diego getaway. Whether you're here to unwind, explore, or entertain, this sunny retreat places you right in the heart of it all.

Superhost

Home in Ramona

4.83 out of 5 average rating, 184 reviews

ENJOY A REAL FARM EXPERIENCE!

EXPERIENCE FARM LIFE! RESTORED OLD 3-BEDROOM 2-BATH FARMHOUSE ON 20 ACRES OF COWS, GOATS, CHICKENS, DUCKS! FEED THEM IF YOU LIKE. COLLECT EGGS FROM THE COOP AND PREPARE THEM IN THE OLD KITCHEN, RING THE TRIANGLE BELL AND DINE IN THE PASTURE! Stocked for breakfast, and since our farm is near town, a short drive for more groceries. Wi-fi. Netflix. Stay for a night or stay a month! Ramona offers antiquing, 3 excellent golf courses, 30 wineries, hiking, horseback riding, birdwatching.

Top guest favorite

Home in Escondido

5 out of 5 average rating, 42 reviews

Lake Sanctuary by Trails - AC & EV

Come experience fresh air, serenity and outdoors right next to Lake Hodges in beautiful San Diego! This home on half acre of horse property is steps away from Lake Hodges trails for walking, jogging, biking, fishing, boating and horseback riding. Impeccably maintained horse shelter is perfect for anyone ready to saddle up and walk miles of horse trails. Hike or bike the many surrounding trails. Birdwatcher’s dream destination. 20 min. to Highland Valley vineyards and the Safari Park.

Guest favorite

Home in Lakeside

5 out of 5 average rating, 23 reviews

San Diego Lake home 4 Bd/Bath/Pool/Putting/Hot tub

This spacious four bedroom home is outfitted in beautiful modern decor. Also, a heated pool, hot tub, putting green and backyard with grill will provide a great space for your family vacation. 20 miles from Downtown San Diego! 20 miles from Balboa Park and the Zoo! 24 miles from the San Diego Airport! 26 miles from Mission Beach/Pacific Beach! 30 miles to the Mexico border crossing! 10 minute drive to Barona Casino! 6 minute drive to Lake Jennings! Book with us today! 🏡🏡

Superhost

Home in Rancho Bernardo

4.96 out of 5 average rating, 24 reviews

Luxurious Lakeview Retreat at Lake Hodges, RB

Make sure to set your stay to 31 nights or more to save big on ST Tax being removed from your pricing Welcome to your dream home, where luxury meets nature. Newly remodeled and beautifully appointed Lakeview Retreat sleeps 12 with five bedrooms and three baths. The house is ideal for couples, families and large groups. This stunning residence boasts breathtaking panoramic views of the Rancho Bernardo Natural Preserve and Lake Hodges, creating a serene and picturesque backdrop.

Guest favorite

Home in San Diego

4.91 out of 5 average rating, 82 reviews

20% OFF- Newly updated guesthome for families

Newly updated peaceful and convenient guesthome in Scripps Ranch. With a private dining room, a fully equipped private kitchen, two cozy bedrooms with desks, and a private bathroom. With central AC and 500Mbp WIFI. 1 minute's driving to a plaza with a supermarket, bank, Starbucks, and restaurants. 5 minutes’ drive to Lake Miramar. Perfect location for exploring UCSD, LaJolla Shores, San Diego Zoo, Sea World, Legoland, Balboa Park, and many other attractions in San Diego.

Superhost

Home in La Costa

Family Ranch near ocean, rivers, and forests. Pool

Enjoy panoramic views & coastal breezes from this beautiful Elfin Forest custom ranch home on 2.5 acres with Pool and Spa. The property is surrounded by hundreds of acres of open space, for hiking, running and riding. Live the private & secluded country lifestyle, only minutes from beaches, shopping, restaurants, golf, Legoland, the San Diego Wild Animal Park and Zoo etc. The best beaches in S. California are within 10 miles and include La Costa, Leucadia and Encinitas.

Guest favorite

Home in San Marcos

4.9 out of 5 average rating, 93 reviews

Lake House 1475 San Diego on the lake

Gorgeous San Diego lake resort, driving distance to the Ocean, 1.5 hours from Disneyland, 40 minutes from Sea World, 20 minutes from Wild Animal Park, 15 minutes from Legoland, 45 minutes from San Diego Zoo If you have a family this a great place to stay If you are a retired couple, this is a great place to stay If you are getting married and looking for an amazing place to have a wedding Lake San Marcos is a gorgeous venue and our house is very close to the resort