
Family-friendly vacation rentals in La Mesa
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in La Mesa
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Private 1 BR Paradise retreat
Private, yet central. It is your exclusive paradise retreat to enjoy from your spacious 1 bedroom guest house located on the lower level of our home. Hang out in the expansive and private backyard with pool, different sitting areas and covered BBQ room. Or maybe a workout in the gym. Centrally located in the Village of La mesa. Just a 1/4 mile jaunt into the quaint village with its numerous assortments of dining options, stores and trolley station. Freeway close to beaches, downtown and airport

NEW construction - Studio near the Village
New studio - Attached Dwelling Unit (ADU) with a private entrance. Walking distance to the Village of La Mesa which has several restaurants, shops and a Vons. Very close to SDSU and quick access to multiple freeways that take you to beaches, mountains, SD Zoo, the nightlife in downtown SD (8, 94, 125). Access to shared laundry room, 2 parking spaces and its own outdoor area. AC & heat. WiFi. Netflix, Hulu with live TV, Apple TV, Disney +, Prime Video and HBO Max. Crib and high chair upon request

Townhouse - Private Yard, La Mesa Village
Enjoy a stylish experience at this centrally-located studio. Walking distance to La Mesa Village, where you can enjoy restaurants, coffee shops, boutiques, & more. With all the things you need in a kitchen to whip up any meal, and a patio to enjoy the San Diego sun. Hop on the trolley to get to anywhere. Bringing more friends or family along with you? We also have another listing, Casa de Pueblo at the same property. 20 min drive to the Beach or Downtown 15 min drive to Balboa Park or Old Town

Spacious 1 Bdrm Unit: king bed, fireplace, parking
Come relax in this bright & spacious 1 bedroom detached unit with private entrance. This room has a king bed, fireplace, full bathroom, table & chairs, mini fridge/freezer, microwave, closet ,dresser, Tv and beautiful mountain views. La Jolla Beaches, downtown San Diego, the Zoo, and Sea World are 25 minutes away. Santee Lakes is just a short drive away where you can enjoy fishing, paddle boating, splash park, biking and picnic area. Mission Gorge Trails is also located just 5 minutes away.

Stunning Guest House 15 min. from Zoo, Downtown
Stunning guest house that's 15 minutes to San Diego Zoo + downtown San Diego. The cottage is decorated with mid-century and one-of-a kind furniture in a comfy living space overlooking a gorgeous garden. Enjoy the the garden on your private deck, watch TV while relaxing in the handcrafted Nicaraguan rocker or 1950s Danish slipper chair. The cottage also has a comfy queen-sized bed and a full kitchen that's stocked with what you'd need. Oh, and all guests arrive to a homemade loaf of bread.

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub
Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

* The Love Suite Artist's Retreat-SDSU-Best Locale
*Come soak up in the artsy feel of this newly renovated large guest suite with private entrance, ideally located in the middle of town close to SDSU. Roll out of bed and Enjoy a cup of coffee in a stylish tranquil patio, then explore ALL of the city’s top attractions a short drive away. This beautiful space is clean, crisp and fully decorated with great style uniquely themed with original art, curated by one of SD’s most established artists. * Enjoy*

Tranquil Poolside Studio
Quiet Poolside Studio Suite! Perfect for visiting family in La Mesa or enjoying everything San Diego has to offer! Please note: this is not a party house. Private side entrance to a relaxing poolside studio. Very quiet with TV, and full kitchen. Comfortable queen size bed and sofa that can sleep one more person comfortably. We are 20 min to the beach, or relax and enjoy the pool! Close to SDSU and easy freeway access to anywhere in San Diego.

Sunny and Affordable Studio W/private outdoor yard
This a great home base to explore San Diego ! It’s a small studio ideal for a one person or couple to get some rest after enjoying San Diego all day. 1 mile to Northpark restaurants/bars/breweries 10-15 mins to Gaslamp,Old town, Seaworld Ocean beach. Full kitchen , coffee corner , gas stove and comfy full size bed. Private entrance from alley. STEET PARKING ONLY - will be very hard to find at night. Used to be a garage decades ago

La Mesa House On a Hill With Mountain Views!
SUNRISE PERCH - A standalone guest house, perfect spot for your San Diego stay! Enjoy inspiring sunrise views from the deck or relax indoors with super fast WiFi and a 43" TV. Enjoy a full kitchen! The king bed is super comfy and the bathroom is stocked. The space is only for those looking for quiet. No partying/loud socializing. Families welcome! Located 20 min from downtown San Diego and 25 min from the nearest beach (Ocean Beach).

Enchanting Barn – La Mesa, San Diego
DESCRIPTION: Relax in this cozy converted barn with a private entrance and secure keyless entry. Sleep comfortably on a California King foam bed and enjoy a TV, Blu-ray player, and desk space. The barn includes a private bathroom with a walk-in shower, plus fresh towels and linens provided. *I have a pet Nigerian Dwarf Goat who would love to meet you!

La Mesa Suite
Mi mesa es su mesa, a beautiful newly built home in sunny La Mesa. Easy access to centrally located shopping center, SDSU and up and coming downtown La Mesa. Short drive down the 8 freeway to the mission beach and downtown SD. Includes everything you need in your home away from home while also providing comfort, security and privacy.
Popular amenities for La Mesa family-friendly rentals
Family-friendly home rentals with a hot tub

Views! Outdoor Cinema•SoakTub +Zoo add-on

Mountain View Retreat in Gated Estate (Hot Tub)

Da Hui Hut - La Mesa’s best view and spa

Former ManCave with Pool & Spa!

Urban Retreat

The Outside Inn at The Tipsy Goat Ranch

Views•Sauna•SoakTub•Firepit+Zoo add-on

Zen Airstream Experience
Family- and pet-friendly home rentals

Insta-worthy! 1 night/many nights, no min required

Green Escape

Winter Wonderland at Bettie Blue!

Lemon Drop Cozy Studio

Fletcher Hills - modern 1 BR.Easy, no step access.

Private cozy cottage

Casita Frida - Relaxing Studio Close to Everything

Kensington Classic/Historic Tudor - Fully Licensed
Family-friendly home rentals with a pool

Lovely Guesthouse in garden setting

Peaceful Valley Ocean View - Restful and Relaxing

Bright Contemporary 5-Bedroom Oasis, Pool and Yard

On park. 1 bed apt.has air & small kitchen+w&d

The BEST NEST Clean, peaceful, private, affordable

Private Poolside Cabana

Bright and spacious home with views, pool & spa.

Comfortable & convenient accommodation @ San Diego
When is the best time to visit La Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | R3,370 ZAR | R3,386 ZAR | R3,487 ZAR | R3,672 ZAR | R3,772 ZAR | R4,191 ZAR | R4,661 ZAR | R4,242 ZAR | R3,655 ZAR | R3,454 ZAR | R3,537 ZAR | R3,588 ZAR |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Quick stats about vacation rentals that are family-friendly in La Mesa

Total vacation rentals
Explore 250 vacation rentals in La Mesa

Nightly prices starting at
La Mesa vacation rentals start at R503 ZAR per night before taxes and fees

Verified guest reviews
Over 12,020 verified reviews to help you choose

Pet-friendly vacation rentals
Find 110 rentals that welcome pets

Vacation rentals with a pool
80 properties feature pools

Rentals with dedicated workspaces
180 properties have a dedicated workspace

Wi-Fi availability
250 of La Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across La Mesa rentals

4.8 Average rating
La Mesa stays are highly rated by guests—averaging 4.8 out of 5!
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