House vacation rentals in La Mesa

The property features a spacious backyard with a heated pool surrounded by lounge chairs. Palm trees line the perimeter, and soft lighting illuminates the outdoor area during sunset. The two-story house overlooks the pool, creating an inviting atmosphere for relaxation and gatherings.

4.95 out of 5 average rating, 213 reviews

XTRA 10% OFF until Nov: Pool, outdoor fire pits, c

Find your family's dream spot in San Diego! Our cozy house sits on a quiet hill, offering privacy and amazing sunset views. Dive into our pool year-round (heating at an additional cost), roast marshmallows by the fire, and cook up fun meals together. With 3 bedrooms and 2 bathrooms, it’s perfect for families, accommodating up to 9 guests. Plus, we're close to all the best attractions. Want a vacation you'll always remember? Send us a message to make it happen! 🌅🏠 We have 3 comfy beds that can

The interior of the studio showcases a spacious layout, featuring a king size bed adorned with yellow and white pillows. A dark gray sofa complements the decor, facing a coffee table with a plant. Large glass doors provide a view of the garden and outdoor seating.

4.9 out of 5 average rating, 269 reviews

Hidden King Suite with Garden, Parking - 4 Guest

Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

4.93 out of 5 average rating, 122 reviews

A living room features a luxury hanging chair suspended from the ceiling. Natural light filters through sheer curtains, illuminating a cozy seating area with a plush sofa and wooden coffee table. A 50” television is mounted above an elegant fireplace, enhancing the room's comfort.

Home in City Heights

Designer Luxury Rental With Pool

Welcome to Wander Haven, a luxury central rental. With it’s on trend design, custom built stock tank pool, array of amenities and thoughtful touches throughout, you won’t ever want to leave. But when do you do decide to venture out and explore all that beautiful San Diego has to offer, you will find the central location gets you to anywhere you want to be in minutes. You’re 15 minutes or less from beaches, downtown, balboa park, sea world, the zoo and hundreds of amazing bars and restaurants.

4.99 out of 5 average rating, 385 reviews

The interior space features a cozy living area with a soft gray sofa, warm wood accents, and natural light flowing in through large windows. A staircase leads to the upper level, where the tree-themed wall art adds character. A dining table is positioned near the double French doors.

Home in Golden Hill

Golden Hill Tree House

The Golden Hill Tree House is an urban oasis hiding in the branches of two mature trees in the heart of San Diego. While you enjoy elevated privacy you can also treat yourself to a soaker tub with double shower heads or settle down in a cozy reading nook to enjoy a good book! You'll also be walking distance to some amazing restaurants and super close to the best of San Diego, including downtown, the beach and the zoo! It's a perfect place to recharge after a long day of business or pleasure!

A spacious living area features a large leather sectional sofa positioned around a circular wooden coffee table. A wall-mounted TV is visible above a decorative fireplace, while natural light streams through a large window adorned with sheer curtains. A dining area is seen in the background.

4.87 out of 5 average rating, 101 reviews

Sunny & Spacious 3BR Retreat w/ Parking & A/C

Centrally located in La Mesa is this newly refurbished home ideal for business or pleasure with all of life’s little luxuries waiting for you to enjoy. The home features open concept living with a gourmet kitchen, a chic dining space, 3 beautiful bedrooms, 2 modern bathrooms and an expansive yard with an outdoor lounge. Walk 10 mins to Grossman Center with a Target, restaurants, cafes, a cinema & Walmart or drive to the heart of San Diego and all its attractions just 20 mins from your door.

4.98 out of 5 average rating, 329 reviews

An outdoor patio area features a round table with four chairs, all adorned with colorful cushions. A large red umbrella provides shade, and a decorative rug adds vibrancy to the stone surface. Surrounding greenery and blooming plants create a serene environment.

Home in Rolando

Travel Writer's Pad

Hello, Bonjour, Hola, Ciao, Ni Hao! For the past two decades my career as a travel journalist has taken me around the globe. I’ve stayed at thousands of accommodations, where I learned personal touches create a comfortable home away from home. Certain places I visited offered extra special amenities, such as Green tea at a Japanese Ryokan & chardonnay infused bath salts at a Mexican posada. These kinds of touches are in the home. I welcome you, but no parties or events at the house. Thanks!

The spacious living area features a comfortable sofa, a dining table with chairs, and a full kitchen with modern appliances. A front-loading washer and dryer are visible, along with a wall-mounted air conditioning unit. Neutral tones are complemented by natural lighting.

4.96 out of 5 average rating, 549 reviews

Clean 1BR/1BA Guest House Peaceful Private Casita

Discover the perfect home away from home in San Diego! Our cozy and tranquil guest house is located just a short drive from the city's top attractions, including the San Diego Zoo and beautiful beaches. Relax and unwind in the comfortable living room and enjoy all the amenities you need for a peaceful stay. With a comfortable queen-sized bed, full kitchen, and fresh towels, you'll have everything you need to feel at home. Book your stay with us today and experience the best of San Diego!

A view into a modern living space reveals a sleek kitchen with bar seating and a spacious dining area. Natural light floods the room through large glass doors, showcasing lush greenery outside. A cozy area is completed with a colorful rug beneath and a inviting seating arrangement.

4.93 out of 5 average rating, 226 reviews

Cottage in the Garden! New! Modern!

COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

A welcoming living area features a spacious beige sectional sofa adorned with patterned throw pillows. Natural light filters through a large window, complemented by soft, flowing curtains. A dark ottoman with decorative details adds a contrasting element to the cozy space.

4.98 out of 5 average rating, 110 reviews

Zen Retreat: 3-Bedroom Oasis near La Mesa Village

Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.

A colorful studio space features turquoise walls and a ceiling fan. A comfortable sofa with decorative pillows is paired with a coffee table. A bed with a floral-patterned comforter sits against a window, while a TV and white refrigerator complete the modern setup.

4.98 out of 5 average rating, 284 reviews

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

4.93 out of 5 average rating, 142 reviews

A comfortable living area features a large sectional sofa with decorative pillows. Natural light streams in through two windows, adorned with dark curtains. A rustic brick fireplace and a low wooden coffee table with magazines add character to the space, enhancing its welcoming ambiance.

Home in Rolando

(Relist!) Relax at a Stunning 1931 Historic Tudor!

Come & enjoy our 1931 historic tudor home! Beautifully rebuilt within the last 2 years. This house has a huge front lawn and space to roam. Enjoy the serenity this large property has to offer. Three peaceful patios to enjoy your morning coffee. The kitchen has an 48-inch 1950’s oven for the chef in the family. Bay windows, arched entryways and original light fixtures make this such a charming place to stay. Centrally located to enjoy everything San Diego & La Mesa has to offer.

4.91 out of 5 average rating, 115 reviews

Home in Kensington

Stylish 1Br Retreat: Parking AC Close 2 Everything

HIGHLIGHTS -Close to SD's main attractions -Stylish and comfy interior w/great lighting -Quaint, walkable neighborhood -Fully renovated kitchen w/new appliances -A/C -Washer/Dryer -Courtyard Patio -1 large, reserved parking spot Enjoy top tier restaurants, cafes and shops along vibrant Adams Ave or explore San Diego’s major attractions less than 15 min away. Downtown for Gaslamp; Balboa Park for museums and Zoo; SDSU for events and games; Mission Beach for fun in the sun.

Popular amenities for La Mesa house rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

Home in University Heights

The outdoor space features a solar-heated pool with soft lighting, alongside a hot tub glowing in green. A dining area with a table and chairs is shaded by a red umbrella. Warm string lights enhance a cozy atmosphere in the evening.

5 out of 5 average rating, 138 reviews

3BR Urban Oasis - Pool and Hot Tub | San Diego

A view of the inviting swimming pool surrounded by a spacious patio. Natural rock elements and vibrant landscaping enhance the outdoor area. The multi-level deck is visible, offering seating options and picturesque canyon surroundings under a clear blue sky.

4.89 out of 5 average rating, 187 reviews

The Queen House

4.95 out of 5 average rating, 115 reviews

A modern living room features a light wooden floor and white walls, complemented by a pink accent wall. A flat-screen TV is mounted above a stylish cabinet, with two potted plants on top. A comfortable seating area includes a rattan chair and a coffee table.

Home in Chula Vista

Casa Bahia Beautiful San Diego Home with Pool

A spacious outdoor area features a clear blue pool surrounded by palm trees. Lounge chairs are positioned nearby, and a shaded table with chairs offers a spot for relaxation. The backyard showcases a privacy fence and ample sunlight.

4.84 out of 5 average rating, 220 reviews

Sunny SD l Pool l BBQ l Pool Loungers l Sleeps 10

Home in University Heights

A tranquil pool area is surrounded by lush landscaping, featuring palm trees and various plants. Two lounge chairs with an umbrella are positioned beside the pool, reflecting a serene evening sky with hues of pink and purple.

4.97 out of 5 average rating, 145 reviews

University Heights Oasis Getaway

4.82 out of 5 average rating, 126 reviews

The outdoor area showcases a clear pool surrounded by a spacious patio. Lounge chairs, a poolside table, and an umbrella are positioned for relaxation. The backdrop features low landscaping with cacti and a glimpse of the house, enhancing the tranquil setting.

Home in Lake Murray

Mid-Century Modern and Contemporary House

A scenic hillside is displayed, featuring a variety of homes nestled among lush greenery. The landscape showcases a blend of residential architecture within a mountainous region, with expansive views of the surrounding area under a clear blue sky.

4.93 out of 5 average rating, 123 reviews

Updated TownHome, Great Location, Fantastic Views

4.96 out of 5 average rating, 176 reviews

A dining space features a round table with four white chairs, complemented by a potted plant. Large glass doors slide open to reveal expansive views of the backyard, pool, and surrounding hills, with soft evening light illuminating the scene.

Home in Spring Valley

Upscale Resort House /Views, Saltwater Pool/Spa !

Weekly house rentals

5 out of 5 average rating, 11 reviews

Airbnb Luxe: The Perfect Blend of Access & Escape

5 out of 5 average rating, 21 reviews

The exterior view of the home displays a warm-toned facade with a welcoming front door. A pathway of pavers leads to the entrance, bordered by mulch. Grass is maintained around the patio area, which features a compact seating arrangement with a small table and chairs.

Home in El Cajon

Cozy 1BR Home with Lovely Front Yard

The living room is furnished with a comfortable loveseat and a coffee table, complemented by a white TV stand supporting a large smart TV. Decorative plants and slender white branches enhance the ambiance, while soft lighting is provided by a standing lamp. Framed artwork adorns the walls.

4.98 out of 5 average rating, 51 reviews

Discover La Mesa: Your Perfect Cozy Base

Superhost

5 out of 5 average rating, 4 reviews

Helix Haven

Superhost

A modern kitchen features sleek black cabinetry and stainless steel appliances. A spacious countertop provides ample prep area, while stylish open shelving displays decorative items. Soft natural light filters in through a window, highlighting a patterned rug on the floor.

4.69 out of 5 average rating, 16 reviews

Modern, Private, & Stylish Home

A modern living space is highlighted with a comfortable gray sofa adorned with vibrant cushions. A textured golden coffee table is positioned in front of the sofa, topped with a game and a decorative bowl. Natural light floods the area, drawing attention to the art on the walls.

4.95 out of 5 average rating, 20 reviews

Chic Casita•Hot tub•BBQ•Patio•4 min SDSU•CentralSD

The front entrance of the house features a covered porch with a wooden deck. Two outdoor chairs are situated on the left side, alongside vibrant plants and flowers. The door is flanked by modern light fixtures, and a large window provides a view of the surrounding greenery.

4.95 out of 5 average rating, 60 reviews

Entire house, fenced yard, and driveway

A modern living room features a sleek black sofa set arranged around a low coffee table. A large television mounted above a black stone fireplace provides entertainment. Natural light streams through expansive windows, highlighting views of the surrounding landscape.

5 out of 5 average rating, 18 reviews

Luxury Hilltop Getaway • Scenic Views

Private house rentals

4.83 out of 5 average rating, 42 reviews

The image showcases a well-maintained house surrounded by a lush green lawn, featuring various palm trees. A fountain is situated in the foreground amidst landscaped gardens, enhancing the serene ambiance of the outdoor space.

Home in Lakeside

A Perfect Pet Friendly Getaway.

4.96 out of 5 average rating, 26 reviews

A breathtaking sunset view showcases vibrant orange and pink hues filling the sky above rolling hills. The scene includes an outdoor deck area with a dining table and chairs, framed by expansive glass doors, inviting the beauty of nature indoors.

Home in Spring Valley

Serenity in San Diego

4.96 out of 5 average rating, 56 reviews

A serene pool area is framed by vibrant green foliage and terracotta walls, with lounge chairs positioned nearby. Majestic mountains rise in the background under a clear blue sky. A shaded picnic table is visible, inviting relaxation in a tranquil outdoor setting.

Home in Jamul

Jamul Hacienda | Couples Retreat | Pool & Views!

5 out of 5 average rating, 24 reviews

Home in Cherokee Point

Garden Retreat in North Park.

5 out of 5 average rating, 13 reviews

A sunlit bedroom features a spacious queen bed adorned with decorative bedding and a light throw. A minimalist bench sits at the foot of the bed, while a desk and lamp occupy a corner. Windows provide natural light, illuminating the soft-toned walls.

Home in El Cajon

Cozy quiet getaway, great mattress (1-br)

5 out of 5 average rating, 62 reviews

A modern kitchen features green cabinetry and a spacious island with seating. Stainless steel appliances and a window above the sink provide natural light. Open shelving displays kitchen essentials, while a door leads to the outside, enhancing accessibility.

Home in San Diego

San Diego's Finest Retreat

5 out of 5 average rating, 93 reviews

A spacious studio features a purple sofa and a queen bed, both adorned with soft blankets and decorative pillows. Vibrant area rugs cover the wooden floor. Natural light floods the room through glass doors, leading to a private patio surrounded by greenery.

Home in San Diego

XLarge Artist's Retreat w/private patio/parking

A spacious living room features a large sectional sofa with orange accent pillows, complemented by a round coffee table. An island with bar stool seating is visible, along with modern kitchen appliances. Natural light enters through the nearby window, highlighting the warm wood tones of the decor.