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Family-friendly vacation rentals in Depew

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Depew

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite

The front entrance of the property features a welcoming porch with decorative railings and vibrant flower beds. A large American flag and other banners hang from the porch, while colorful flowers provide a lively accent. The pathway is well-maintained, leading to the main door.

Guest suite in Buffalo

4.99 out of 5 average rating, 941 reviews

Sleep Under The Stars

Through hard work and dedication, my listing has been ranked in the TOP 5%🏆of all Airbnb listings worldwide. The space I offer is an ENTIRE 2nd floor "MINI SUITE". The living quarters include a PRIVATE BATHROOM, BEDROOM, DEN & CAFE'. The space is ALL YOURS to enjoy & the extras are plentiful. Coffee, water, fresh fruit, yogurt, & snacks/candy are available. My goal & Mission Statement is to provide a nice comfortable landing spot, & offer helpful advice & valuable insight to my cherished guests

A cozy sleeping area features a spacious bed with a light-colored coverlet. Decorative pillows are arranged at the head of the bed, complemented by bedside tables and lamps. Natural light filters through sheer white curtains, enhancing the calming ambiance of the room.

Guesthouse in Cheektowaga

4.78 out of 5 average rating, 134 reviews

Warm & Cozy private Guesthouse/ Entire place.

Hi there! This is Aklima and Farhad, and we’re thrilled to have you stay at our guest house. It’s connected to our house, but both have their own private entrances. Just a friendly reminder, you might spot our kids playing in the backyard, so please be mindful of that. We love living here and meeting new people, which is why we started Airbnb. We’re committed to providing the best hospitality at an affordable price. This place is surrounded by nature and in a peaceful area! Enjoy your stay!

A living area is displayed, featuring a dark sofa alongside a patterned armchair. A decorative area rug covers the wooden floor. The background shows a kitchen space with bar seating and modern appliances, contributing to a welcoming atmosphere.

Apartment in Cheektowaga

4.94 out of 5 average rating, 224 reviews

Close to Niagara Falls and Airport, Mall nearby

Niagara Falls is only 30minutes away.Very nice neighborhood. 4minutes from Galleria Mall.Plus many more stores nearby.Many places to eat and have some drinks! Sleeps-5 plus we have a clean pack and play for your little one. Has own keypad entrance. Full sleeper sofa in living room. One bedroom has a queen bed and tv. The 2nd bedroom has a twin bed and offers tv and a workspace. Very clean! Kid friendly and pet friendly. Pets can do their business out front. There are dogs that use the back yard.

An aerial view of a round above-ground pool, featuring vibrant floating pool toys in bright colors. Adjacent to the pool, a composite deck is visible with stylish outdoor furniture arranged for relaxation, set against a backdrop of green grass.

Apartment in Depew

4.9 out of 5 average rating, 289 reviews

Modern Oasis Pool & Hot Tub near Buf/Falls/Stadium

This spacious 3 bedroom 2nd floor apartment is updated with you in mind. The entire space has everything you could want during your stay. This is the perfect spot in the Buffalo area - close to the airport 10-15min, 15min to downtown, 18min to Bills Stadium, 40min to Niagara Falls & minutes from many shopping options including the famous Galleria Mall & Niagara Outlets. Both short term & long term stays are welcome. The space easily accommodates individuals, couples, families, & groups.

Top guest favorite

A cozy bedroom features a wooden sleigh bed with a plaid comforter. A decorative lamp sits on a nightstand beside the bed. A trunk labeled 'LOVE' is placed at the foot of the bed, and a window with a checkered valance allows natural light to filter in.

Guest suite in Lancaster

4.98 out of 5 average rating, 172 reviews

"The Suite Spot", Adorable apartment with deck

Kick back and relax in this calm, stylish space. This second floor apartment boasts a newly remodeled bathroom, a full kitchen, a comfortable bedroom perfect for two & a cozy sitting area with chairs that convert into twin beds. It also offers off street parking for one vehicle & a private entrance on the deck. It's a perfect place to relax & enjoy the summer & fall. Along with our dog Toby & our cat Taffy who will welcome you (but will not be a bother) we invite you to enjoy our home.

A living area features a wall-mounted television above a rustic wooden table. A small ladder shelf stands to the left, adorned with decorative items. The kitchen area is visible in the background, showcasing wooden cabinets and coffee-making equipment.

Apartment in Depew

4.8 out of 5 average rating, 400 reviews

The Shecave - 2 Bedroom Apt

This is perfect for your staycation or for a cozy pit stop. If you’re looking for a short term, no frills, respite, or workplace area, this is the place for you. This is not intended as a party house. Plenty of take out, pick up, or delivery of food. We PRIDE ourselves on the CLEANLINESS of our spaces. Great for a visit to Niagara Falls. Close to Galleria Mall. Quiet and safe neighborhood. **Please be at least 25 book.** **Photo ID will be required from you after booking.**

Top guest favorite

The living area features a navy blue carpet with a sofa and coffee table situated in front. A fully equipped kitchen is seen in the background, equipped with dark wooden cabinets and modern appliances. Light fixtures enhance the well-lit atmosphere.

Apartment in Buffalo

4.96 out of 5 average rating, 343 reviews

Cozy Apartment in LarkinVille (Unit 2)

If this listing is not available please check out my other listings This 1st floor apartment features an open concept kitchen & living room with stove, refrigerator & microwave. A queen sleeper sofa & 54" smart TV are in the living room. The bedroom has a queen bed & dresser. The space features a In unit washer & dryer soaker jacuzzi tub and A/C mini split to help cool down the space. This is a mix use property with periment tenants as well as other guest. Noise is typically low

Top guest favorite

A comfortably arranged living area features two light gray sofas adorned with decorative pillows, set around a round black coffee table. Natural light enters through the large windows, illuminating a woven area rug on the hardwood floor, while lamps provide soft ambient lighting.

Guest suite in Williamsville

4.95 out of 5 average rating, 299 reviews

**Village Home In Buffalo- BEST LOCATION!**

Welcome “home” and discover why Buffalo is called the ‘City of Good Neighbors’! Whether it’s for a day, week, or even longer, feel comfortable and cozy, in this 1 bedroom apartment. Being less than 2 miles from the Buffalo Niagara Int’l airport, a quick Uber ride will bring you to Williamsville and offer you a true Buffalo experience. Enjoy the small town vibe of the village, and allow Williamsville to be your gateway to adventure! (Downtown Buffalo- 9mi, Niagara Falls- 17mi. )

A small table surrounded by four colorful chairs is positioned near a window, which is adorned with light curtains. Books are displayed on wall-mounted shelves nearby, and an air conditioning unit is visible. A bedside lamp adds soft illumination to the space.

Home in Buffalo

4.93 out of 5 average rating, 118 reviews

Cozy Home for Relaxing Getaways

Nestled in a peaceful neighborhood, our beautiful 1115 square feet ranch house offers a charming design. As you step inside, you are greeted by a spacious living area adorned with tasteful décor and plush furnishings. The kitchen is a chef's dream, our home offers kids toys and books. Book your stay at our beautiful home and experience a truly unforgettable getaway. We look forward to hosting you and making your stay a memorable one. Welcome to your home away from home.

A spacious kitchen features warm wooden cabinetry and modern stainless steel appliances. Natural light floods through windows, illuminating the open layout that connects to a cozy living area. A decorative light fixture hangs from the vaulted ceiling, enhancing the inviting design.

Home in Buffalo

4.95 out of 5 average rating, 133 reviews

KING BED! Brand New! Fabulous & Fresh Farmhouse!

Top to bottom BRAND NEW home! Custom interior design & a relaxing, SPARKLING space! KING primary en-suite w/ walk in closet! 1st floor laundry, kitchen w/ every cooking amenity possible- coffee/tea bar, filtered water & ice on fridge, FREE parking & WIFI, private yard; deck w/ gas grill & fire pit, family friendly-high chair & pack n play available! Minutes from TONS of malls & yummy restaurants. Close to airport & train station. Dead End Street!

Top guest favorite

The studio features an open layout with a cozy seating area including a gray sofa and matching chairs. A dining table accommodates four, and a spacious bed is present in the corner. Natural light filters through the window treatments, highlighting the neutral color scheme.

Guest suite in Lancaster

4.91 out of 5 average rating, 180 reviews

Work or Play this is your Home Away!

Newly remodeled private studio with private entrance. Lots of parking space. 700sq ft.of living space for you to enjoy! Private balcony overlooking stunning backyard views with a pond. Only 13 min away from Buffalo airport! Shopping centers within a mile. Downtown Buffalo- 20 min. drive Flix Movie Theater- 2 min. drive New Era field- 20 min. drive Niagara Falls- 40min. drive Galleria Mall- 12 min. drive

A charming exterior view showcases a white picket fence surrounding a well-kept yard. A lush green lawn is framed by flower beds, and a gazebo is visible in the background, complemented by mature trees providing shade.

Apartment in Williamsville

4.94 out of 5 average rating, 142 reviews

Cozy Williamsville apartment at Madison Place

Cozy 1 bedroom 2nd floor apartment Eat in kitchen with countertop height seating 2 Queen size beds (bed & fold out couch) Brand new built in dishwasher & microwave oven All cookware, silverware & kitchen appliances Fully furnished with all linens, towels and starter supply of soaps, shampoos. Ample closet space and storage Whole house water filter Laundry located in basement Off street parking for 2 cars

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Popular amenities for Depew family-friendly rentals

Free parking on premises

Air conditioning

Family-friendly home rentals with a hot tub

A spacious living area features a comfortable sofa and a wooden coffee table, complemented by a flat-screen TV mounted on the wall. Natural light filters through the skylight and window, illuminating the modern decor that includes a stylish bed and tasteful accents.

Loft in Fort Erie

4.98 out of 5 average rating, 138 reviews

Mins. to Crystal Beach | Loft| Hot Tub| Spa Bath!

A cozy fire pit is surrounded by four colorful adirondack chairs, set in a pebbled area. Soft outdoor lights hang in the background, illuminating the space while creating a warm ambiance during the evening.

Home in Buffalo

4.85 out of 5 average rating, 184 reviews

Near |UB |Duff’s| Niagara Falls| Fire Pit & HotTub

The spacious bedroom features a large, upholstered bed with crisp linens. Two bedside lamps provide soft lighting, and wood accents are present in the dressers and seating. Plush rugs cover the hardwood floor, while neatly arranged towels are displayed on a wooden bench.

Castle in Elmwood Village

4.9 out of 5 average rating, 227 reviews

King Luxury Fireplace Loft HotTub Gym Bball Crt EV

A dining area features a large, ornate dining table surrounded by eight intricately designed chairs. A vibrant area rug is placed beneath the table, and a pendant light illuminates the space. Bar stools are positioned at a counter in the background, enhancing the open layout.

Home in Buffalo

4.81 out of 5 average rating, 208 reviews

Downtown Home W HOT TUB Private Deck & HiddenRoom

A cozy bedroom features a spacious bed with neutral bedding and decorative pillows. Light natural tones are enhanced by soft curtains and wall art. A small chair and nightstand are included, with a tray displayed on the bed, adding a touch of warmth to the inviting space.

Home in North Tonawanda

4.9 out of 5 average rating, 154 reviews

Hot tub relaxing space 20 min from Niagara Falls

An outdoor hot tub is nestled beneath a wooden pergola, featuring jets and seating. In the background, a swimming pool is visible, surrounded by greenery and blue skies, evoking a relaxing atmosphere.

Cottage in Niagara-on-the-Lake

4.89 out of 5 average rating, 296 reviews

Modern Farmhouse XL Hot Tub NOTL 15Mins- Falls

Cottage in Fort Erie

4.96 out of 5 average rating, 117 reviews

Fall Retreat| HotTub| Lake Views| Fire Pit

An aerial view of a spacious backyard features a private pool surrounded by a deck area. A covered seating area is visible along with play equipment for children. Lush green grass and trees frame the property, enhancing the outdoor space's appeal.

Bungalow in Chippawa

4.9 out of 5 average rating, 115 reviews

Niagara Luxury villa-hottub, pool, water view

Family- and pet-friendly home rentals

A welcome sign to Eden, New York, highlights the town's name and nickname, 'The Garden Spot of New York State.' Established in 1812, the sign notes a population of 8076. The green and white structure is surrounded by a grassy area and trees in the background.

Apartment in Eden

4.89 out of 5 average rating, 119 reviews

The Lofts of Eden

A cozy living area features a gray sofa adorned with decorative pillows and a plush armchair. Soft natural light filters through sheer curtains, illuminating the space. An accent table with a lamp is positioned next to the armchair, adding functionality to the inviting room.

Apartment in Buffalo

4.83 out of 5 average rating, 293 reviews

lovely apt on Niagara River min to downtown,falls

Top guest favorite

A green, textured sectional sofa is arranged in a cozy corner with soft cushions in shades of yellow and orange. A floor lamp stands nearby, illuminating the space. Large windows with decorative glass filters natural light, and a framed artwork adds a touch of color to the wall.

Apartment in Buffalo

4.96 out of 5 average rating, 178 reviews

Inviting King & Queen-parking-laundry-pets

An open living room features a modern farmhouse-inspired fireplace wall with a wall-mounted TV above it. Cozy seating arrangements include a gray couch and armchair with yellow and gray accents, while a wooden coffee table occupies the center of the space.

Home in Kenmore

4.96 out of 5 average rating, 111 reviews

Modern Kenmore Getaway | Renovated Home in Buffalo

A modern living area features a dark accent wall and a stylish fireplace, with a flat-screen TV mounted above. A cozy armchair and a wooden side table are positioned on a textured area rug, while a round coffee table sits at the center of the space.

Apartment in Elmwood Village

4.85 out of 5 average rating, 155 reviews

Five Points Apartment Lower Unit

Top guest favorite

The spacious guest suite features a queen bed with a red coverlet, a love seat with red accents, and a wooden coffee table. Two windows allow natural light to fill the room, while a circular area rug adds texture to the hardwood floor.

Guest suite in North Buffalo

4.87 out of 5 average rating, 284 reviews

Parkside Suite in Desired Urban Neighborhood

Top guest favorite

The living area is furnished with a stylish chair and a small table, offering a cozy corner. A mounted flat-screen TV is above a decorative non-working fireplace, accompanied by a flower vase. Built-in shelves display pottery and knick-knacks, complemented by a view into the dining area.

Apartment in North Buffalo

4.97 out of 5 average rating, 242 reviews

Charming Upper in Lively Entertainment District

A modern kitchen features a central island with bar seating for three. Stainless steel appliances, including a microwave and dishwasher, complement the granite countertops. Exposed brick adds character, while a wooden dining table is positioned against the wall, enhancing the space's functionality.

Apartment in Buffalo

4.9 out of 5 average rating, 147 reviews

3BR Family + Pet-Friendly • Driveway + Backyard

Family-friendly home rentals with a pool

Villa in Niagara Falls

4.73 out of 5 average rating, 361 reviews

C&J Cozy 2BR/a 3rd BR is available at an up charge

Top guest favorite

The shared backyard features a rectangular pool bordered by lounge chairs and a grassy area. A covered patio is visible alongside, providing a space for seating. The setting is surrounded by trees, creating a tranquil atmosphere for relaxation.

Apartment in Niagara Falls

4.9 out of 5 average rating, 138 reviews

Niagara Falls Retreat: Walk to the Wonders

A spacious living area features a plush brown couch and a cozy white lounge chair next to a modern black coffee table. A well-lit dining area with seating for eight is visible, along with a bright kitchen and stylish decor elements.

Home in Niagara Falls

4.91 out of 5 average rating, 120 reviews

Luxury Family Oasis W/ GameRoom/King Bed/Hot Tub

A private swimming pool is surrounded by well-maintained gardens and mature trees. Lounge chairs are positioned nearby for relaxation. The pool features steps leading into the water, while a covered seating area is partially visible, inviting outdoor enjoyment.

Guest suite in Niagara Falls

4.87 out of 5 average rating, 139 reviews

Comfy suite with private pool(4-6)

An inviting kitchen is showcased with wooden cabinetry and stainless steel appliances. A spacious island with seating for four provides a central gathering spot. Natural light filters in through the large window, highlighting the elegant countertops and stone backsplash.

Home in Cheektowaga

5 out of 5 average rating, 3 reviews

Cute and Spacious George Urban Home!

Top guest favorite

A fenced-in area showcases a private heated pool surrounded by lush greenery and blooming flowers. Lounge chairs are positioned nearby on the patio, providing a space for relaxation. The pool features clear water and is well-maintained, inviting guests for a refreshing swim.

4.91 out of 5 average rating, 117 reviews

Carols Country Inn ☆☆☆☆☆

An aerial view highlights the expansive grounds of Vine Ridge Resort, showcasing the nearby river and surrounding greenery. The property features two swimming pools, spacious areas for parking, and nearby vineyards, all set against a backdrop of trees and open landscapes.

Cottage in Niagara-on-the-Lake

4.74 out of 5 average rating, 131 reviews

Niagara on the Lake Cottage Vine Ridge Resort

Top guest favorite

An inviting inground pool is surrounded by a spacious patio, featuring lounge chairs for relaxation. The water is crystal clear, reflecting the bright blue sky above. A cozy retreat is visible in the background, nestled among greenery that enhances the tranquil setting.

Place to stay in Elma

4.97 out of 5 average rating, 31 reviews

Labor of Love Artist's Retreat

Destinations to explore