Vacation rentals in Depew

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Top-rated vacation rentals in Depew

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
The dining area features a modern table set for six, with a soft gray table runner and fresh flowers in a central vase. A stylish chandelier provides overhead lighting, complemented by a mirror on the wall. The kitchen area is visible, showcasing stainless steel appliances.
Home in Buffalo
4.96 out of 5 average rating, 103 reviews

Lovely 3 bed 2 bath &2 living rm ranch home

Your family will be close to everything when you stay at this centrally-located place. 3 bedrooms 1 bathroom ranch home in located quiet and beautiful neighborhood. All of appliances are brand new and renovated kitchen. centrally-located this place you can reach all kinds of restaurants 2-10 minutes drive. Gallaria Mall 2 minutes drive. Many of grocery stores are here. Niagara Falls 30 minutes drive, Highmark Stadium 15 minutes drive Downtown 10 minutes drive so many parks are here 2- 10 min

Top guest favorite
A well-appointed kitchen is presented with white cabinetry and granite countertops. Modern appliances are included, along with a large window that provides natural light. A waste bin is positioned to the side, and textured tiles adorn the floor, enhancing the space's functionality.
Apartment in Cheektowaga
4.95 out of 5 average rating, 244 reviews

Close to Niagara Falls and Airport, Mall nearby

Niagara Falls is only 30minutes away.Very nice neighborhood. 4minutes from Galleria Mall.Plus many more stores nearby.Many places to eat and have some drinks! Sleeps-5 plus we have a clean pack and play for your little one. Has own keypad entrance. Full sleeper sofa in living room. One bedroom has a queen bed and tv. The 2nd bedroom has a twin bed and offers tv and a workspace. Very clean! Kid friendly and pet friendly. Pets can do their business out front. There are dogs that use the back yard.

Top guest favorite
Apartment in Cheektowaga
5 out of 5 average rating, 30 reviews

Convenient cozy two bedroom apartment

Convenient newly furnished 2 bedroom apartment near Buffalo Airport, Centrally located near Buffalo and Niagara Falls. Close to University at Buffalo. Five minutes to Buffalo International Airport. Enjoy this private 2 bedroom apt. steps from a walking park & playground. Enjoy Buffalo cuisine from many local restaurants. Come cheer on the Bills or Sabres or attend one of the many festivals and music events Buffalo has to offer. The Galleria Mall is minutes away as well as supermarkets.

Superhost
A comfortable living area is displayed, featuring a large sectional sofa with decorative cushions and a wooden coffee table. A 50" Smart 4K TV is positioned on a stand, showcasing a scenic landscape. The space is illuminated by natural light from the adjacent kitchen.
Apartment in Depew
4.91 out of 5 average rating, 117 reviews

Fireman's Park View

Book your stay at our homey and welcoming 3 bedroom space, designed for guests to enjoy. We are a short 10 min drive from the Buffalo Airport. There is plenty to do during your stay: downtown Buffalo and Niagara Falls are both a 20 min drive, and our quiet, safe neighborhood is the perfect place to relax for the evening. We suggest taking a walk at Reinstein Woods nature preserve. With a park in the backyard and access to an abundance of restaurants and shops nearby, you will love this space!

Top guest favorite
A comfortable living area features a cozy fireplace set within a brick accent wall, providing a focal point. A large TV is positioned nearby, while a soft leather sofa and a vibrant orange chair offer ample seating. Natural light enters through the windows, enhancing the inviting ambiance.
Apartment in Clarence
4.99 out of 5 average rating, 159 reviews

Meticulous Main St. Ranch 2 Bd Lux Apt. Rear Unit

This well-appointed, recently renovated, 1200 sq. ft. ranch duplex apt. is located on Main St in the heart of charming & historic Clarence, NY. The community is a beautiful, safe, and family friendly suburb of Buffalo, NY. The entire apt. is on one level, with four parking spaces next to the entrance. The beautiful open concept floor plan provides an abundance of natural lighting, creating a comfortable airy feeling, that is perfect for small gatherings, business travelers, and entertaining.

Top guest favorite
Home in Depew
5 out of 5 average rating, 18 reviews

*HOME GYM in Neighborhood home Near Airport*

New Listing with Superhost Co-Host! Relax and unwind in this private and comfortable, home away from home, located in a quiet family-friendly neighborhood. You’ll be close to anything and everything you may need while staying in the Buffalo area! Buffalo Niagara International Airport: 10 min Wegmans: 4 min Village of Williamsville: 10 min Buffalo Niagara Medical Campus: 13 min Downtown Buffalo: 15 min KeyBank Center: 18 min Highmark Stadium: 23 min (Go Bills! 🏈) Niagara Falls: 32 min

Guest favorite
A living area features a wall-mounted television above a rustic wooden table. A small ladder shelf stands to the left, adorned with decorative items. The kitchen area is visible in the background, showcasing wooden cabinets and coffee-making equipment.
Apartment in Depew
4.8 out of 5 average rating, 419 reviews

The Shecave - 2 Bedroom Apt

This is perfect for your staycation or for a cozy pit stop. If you’re looking for a short term, no frills, respite, or workplace area, this is the place for you. This is not intended as a party house. Plenty of take out, pick up, or delivery of food. We PRIDE ourselves on the CLEANLINESS of our spaces. Great for a visit to Niagara Falls. Close to Galleria Mall. Quiet and safe neighborhood. **Please be at least 25 book.** **Photo ID will be required from you after booking.**

Guest favorite
A cozy bedroom features a wooden sleigh bed with a plaid comforter. A decorative lamp sits on a nightstand beside the bed. A trunk labeled 'LOVE' is placed at the foot of the bed, and a window with a checkered valance allows natural light to filter in.
Guest suite in Lancaster
4.96 out of 5 average rating, 195 reviews

"The Suite Spot", Adorable apartment with deck

Kick back and relax in this calm, stylish space. This second floor apartment boasts a newly remodeled bathroom, a full kitchen, a comfortable bedroom perfect for two & a cozy sitting area with chairs that convert into twin beds. It also offers off street parking for one vehicle & a private entrance on the deck. It's a perfect place to relax & enjoy the summer & fall. Along with our cat Taffy who will welcome you (but will not be a bother) we invite you to enjoy our home.

Top guest favorite
The studio features an open layout with a cozy seating area including a gray sofa and matching chairs. A dining table accommodates four, and a spacious bed is present in the corner. Natural light filters through the window treatments, highlighting the neutral color scheme.
Guest suite in Lancaster
4.91 out of 5 average rating, 192 reviews

Work or Play this is your Home Away!

Newly remodeled private studio with private entrance. Lots of parking space. 700sq ft.of living space for you to enjoy! Private balcony overlooking stunning backyard views with a pond. Only 13 min away from Buffalo airport! Shopping centers within a mile. Downtown Buffalo- 20 min. drive Flix Movie Theater- 2 min. drive New Era field- 20 min. drive Niagara Falls- 40min. drive Galleria Mall- 12 min. drive

Guest favorite
A charming cottage is set against a vibrant sunset sky, with soft hues illuminating the surrounding trees. The front entrance is framed by a welcoming porch, leading to a grassy area that gradually slopes away from the building.
Cottage in East Aurora
4.91 out of 5 average rating, 209 reviews

Charming 2 bedroom cottage on the EA golf course

Welcome to Maplelinks. Relax at this quiet and quaint 100 year old 2 bedroom/1 bathroom guest cottage located right on the East Aurora Country Club less than a mile outside of the village. 15 minutes from Bills games. 20 minutes from downtown Buffalo. 20 minutes from skiing. Private off street parking. Self check-in anytime after 3pm. (Sorry. No pets.)

Guest favorite
The living room features a grey sofa and a brown leather couch, complemented by a wooden coffee table with decorative items. A framed artwork is displayed on the wall, and light streams through the windows with wooden trim, enhancing the cozy atmosphere of the space.
Home in Depew
4.92 out of 5 average rating, 36 reviews

Home sweet home away

Welcome to this newly remodeled bright gem in the village of Depew. Perfect for anyone who wishes to be close to most of what Buffalo has to offer! Spacious enough for a family and not too overwhelming for the traveling professional. This house has everything you need to feel like you are at home.

Guest favorite
A duplex apartment is displayed with a light grey exterior and brick accents. A well-maintained lawn features manicured shrubbery on either side of the front entrance. A clear pathway leads to the front door, while two vehicles are visible in the driveway and nearby street.
Home in Cheektowaga
4.87 out of 5 average rating, 87 reviews

Cozy Duplex Near Airport | Niagara Falls |Highmark

Welcome to Our Home! This is a spacious duplex apartment featuring two bedrooms (one with a king bed with a baby crib and the other with two twin beds) and one bathroom, along with a sunroom to relax. Parking: One car on the driveway and FREE street parking.

Popular amenities for Depew vacation rentals

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