House vacation rentals in Seneca
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Top-rated house rentals in Seneca
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Seneca house rentals
House rentals with a pool
Home in West Union
4.95 out of 5 average rating, 137 reviewsSunsets and Siestas -Lake Keowee home near Clemson
Mar 8 – 15
Home in Greenville
5.0 out of 5 average rating, 106 reviewsPalmetto Escape - Pool- Firepit- 6.6 mi DTWN GVL
Nov 17 – 24
Home in Greenville
4.88 out of 5 average rating, 116 reviewsSaluda Splash Home
Oct 11 – 18
Home in Westminster
5.0 out of 5 average rating, 19 reviewsThe Hilltop Hideaway at Lake Hartwell
Sep 4 – 11
Home in Westminster
4.99 out of 5 average rating, 75 reviewsDream Weaver Lakefront• jacuzzi• dog friendly home
Dec 27 – Jan 3
Home in Salem
5.0 out of 5 average rating, 9 reviewsNewly Updated | Lake Keowee | Pool | Amenities
Dec 8 – 15
Home in Seneca
5.0 out of 5 average rating, 11 reviewsKeowee Lakeside with pool for 16
Sep 22 – 29
Home in Walhalla
4.94 out of 5 average rating, 31 reviewsJana Retreat Pool 3 BR/2 Bath
Feb 16 – 23
Weekly house rentals
Home in Central
4.97 out of 5 average rating, 128 reviewsClemson Carriage House | Private Guest House
Jul 4 – 11
Home in Seneca
4.85 out of 5 average rating, 174 reviewsCozy Lake House 5 miles from Clemson w Dock
Jun 23 – 30
Home in Seneca
4.97 out of 5 average rating, 120 reviewsLake Hartwell house w/ dock 2 miles from Clemson.
Mar 24 – 31
Home in Clayton
4.96 out of 5 average rating, 330 reviewsThe Extra House
Jun 26 – Jul 3
Home in Pendleton
4.99 out of 5 average rating, 130 reviews3 BR/2BA Cottage in Pendleton - 9 Miles to Clemson
Jun 24 – Jul 1
Home in Seneca
4.92 out of 5 average rating, 37 reviewsSouth Cove Bungalow Lake Keowee
Aug 3 – 10
Home in Westminster
4.94 out of 5 average rating, 16 reviewsMountain Road Cottage
Jul 24 – 31
Home in Seneca
5.0 out of 5 average rating, 46 reviewsModern & Cozy Cottage-12 min. from Clemson Uni.
Aug 4 – 11
Private house rentals
Home in Walhalla
4.91 out of 5 average rating, 43 reviewsThe Yellow Quilt in Walhalla
Jul 31 – Aug 7
Home in Seneca
5.0 out of 5 average rating, 19 reviewsCozy 3/2 Modern Home in Seneca and Clemson Area
Aug 26 – Sep 2
Home in Seneca
5.0 out of 5 average rating, 55 reviewsLake Hartwell Dock, Lakefront, Kayaks, Clemson 4BR
Dec 5 – 12
Home in Tamassee
5.0 out of 5 average rating, 24 reviewsWhitewater Lake Front Cottage
Feb 20 – 27
Home in Anderson
5.0 out of 5 average rating, 65 reviewsLakefront dock *Hot tub* Anderson Clemson King bed
Sep 29 – Oct 6
Home in Seneca
5.0 out of 5 average rating, 3 reviewsLakefront Mid-Century Dream Home / 3 mi to Clemson
Sep 11 – 18
Home in Clemson
5.0 out of 5 average rating, 19 reviewsVaulted Ceilings & Accent Windows--1 mile from CU
May 16 – 23
Home in Seneca
4.96 out of 5 average rating, 70 reviewsPerfect Lake Hartwell Getaway! Gorgeous Views!
Mar 2 – 9
Quick stats about house rentals in Seneca
Total rentals
30 properties
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
30 properties are a good fit for families
Total number of reviews
1.3K reviews
Nightly prices starting at
R740 ZAR before taxes and fees
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