Vacation rentals in Seneca

4.94 out of 5 average rating, 229 reviews

A gravel area bordered by smooth stones features lounge chairs and a fire pit. A deck is accessible from the brown barn structure in the background, partially surrounded by greenery and trees, providing a serene outdoor space.

Tiny home in Pickens

Lazy Bear Retreat by the Creek

The perfect romantic getaway! Come soak in our hot tub while listening to the water flowing. Lights surround our tiny house to create the mood. Lounge during the day in the sun. Want to stay in and eat? Enjoy our grill and table outside or cook inside. Want to eat out? Aunt Sue's and Pumpkintown General store are both so close. Both have delicious homemade meals! Victoria Valley Vineyards is perfect for wine tasting. We provide a year long state park pass. Tablerock state park minutes from you.

5 out of 5 average rating, 63 reviews

Two white lounge chairs are positioned on a sandy beach area beside a calm lake. Soft waves lap at the shore, with lush greenery framing the water. A partly cloudy sky reflects sunlight, enhancing the serene outdoor setting.

Townhouse in Salem

Lake & Mountain Resort Escape-Pools, Golf, Boat

Escape to this stunning dog-friendly 3BR, 3BA home in the prestigious Keowee Key Resort—your perfect haven for up to 8 guests! Surrounded by lush forests, this luxurious retreat offers spacious living areas, resort amenities, and endless opportunities for fun. Tee off on the golf course, boat the lake, dive into pools, or challenge the group to ping-pong and board games in the cozy basement. End your day by the deck fireplace under the stars. Adventure, relaxation, and cherished memories await!

4.92 out of 5 average rating, 210 reviews

Cottage in Highlands

RiverBunk, Highlands Vintage Treasure

RiverBunk fronts Culasaga River in the historic Mirror Lake area on Hicks Road. 1 mi from downtown, shopping, restaurants, art, spa, wine garden and outdoor activities. Truly a one of a kind cottage that will bring you back and wow you with coziness and romantic memories. Perfect for the couple who wants to escape but tip out to one of the many eateries or waterfalls in the area. Hiking, zip-line, seasonal snow tubing and local galleries will keep you entertained. Amazing New Dock and Dingy

4.98 out of 5 average rating, 157 reviews

The entrance of a charming cottage features a wooden ramp leading to a door framed by a small covered porch. A hanging flower basket adds a touch of greenery, while the cottage's rustic exterior is complemented by decorative shutters and a metal roof.

Cottage in Highlands

Comfy Creek Side Cottage In Town; Perfect For Two

This tastefully decorated small cottage is conveniently located just three blocks to downtown Highlands. Just a 10-12 minute walk to the shops and restaurants on Main Street. Also within walking distance is The Botanical Gardens, Sunset Rock, and Kelsey-Hutchinson Park. There are several trails directly accessible from the doorsteps of this creek side sweet spot. All new furnishings including queen sized Sealy Posturepedic Cushion Firm mattress, all cotton linen, and outdoor furniture on deck.

4.82 out of 5 average rating, 163 reviews

A mountain cottage is nestled among greenery, showcasing a balcony that offers expansive views of the surrounding landscape. The exterior features a blend of wood and modern design elements, complemented by a driveway leading to a garage.

Cottage in Dillard

Highlands Mountaintop Escape

A mountaintop escape near Highlands, NC with spectacular views from 4000’ right off the back covered deck. Our cozy cottage has 2 bedrooms, newly remodeled bathroom and kitchen, hardwoods, outdoor patio with fire table and grill. No better place to relax, escape and enjoy the mountains and view. Plenty to do - local hikes, fishing, and a mountain coaster and tubing year round at Highlands Outpost just a few minutes down the road. Highlands is only 10 miles away for a mountain city adventure.

5 out of 5 average rating, 40 reviews

The entrance features a welcoming porch supported by wooden beams, leading to a pair of stylish wooden doors. Natural stone accents the steps, set against a backdrop of trees, highlighting a blend of modern and rustic architectural elements.

Home in Highlands

Glen Falls Luxury Cabin

This new mountain retreat near a magnificent waterfall in the gorgeous mountain town of Highlands, North Carolina! This spacious Airbnb offers modern comfort in a serene setting with an easy 6-minute drive to all Main Street offers. With beautiful surroundings, cozy bedrooms, a warm fireplace, and an expansive eat-in kitchen, you're bound to have a memorable stay. Explore the trails, relax on the deck, and embrace the beauty of the mountains. We'd love to host you for a rejuvenating getaway!

4.86 out of 5 average rating, 202 reviews

A spacious back deck features lounge chairs positioned for relaxation, with a blue umbrella providing shade. Large glass doors lead into the home, surrounded by large windows that enhance natural light. The surrounding trees add greenery and tranquility to the space.

Home in Anderson

Lake Living with Amazing Views of Lake Hartwell

Stunning lake views in highly popular The Shoals in Portman Marina located on Lake Hartwell. Bring your pets with you, we are pet-friendly, and they'll love running around the fenced in backyard. Very large back deck overlooking the lake while you have morning coffee, grill or just relax! We also are located in a very nice, quiet neighborhood in cul de sac. Short drive to Clemson University for games or student/family events. Also, short drive to downtown Anderson and Anderson University.

4.92 out of 5 average rating, 62 reviews

Home in Mountain Rest

Lake Cabin Mt Rest SC Waterfalls & Great Hikes

Looking for that perfect, get-away-retreat, on a private mountain lake? Here it is! This , is exactly what you need. With all the new mountain biking trails, hiking trails, waterfalls, white water rafting and some of the best fly-fishing in the southeast, and the lake itself, this is the outdoor enthusiast dream. The 1500 sq ft home was built in 2006 and has been well cared for. Not suitable for non - swimming children. Kayak and Canoe available, bring your fishing poles.

4.98 out of 5 average rating, 53 reviews

A modern kitchen and dining area features a wooden dining table with white chairs, a stainless steel stove, and a refrigerator. Natural wood accents on the ceiling complement the bright cabinetry. A window provides outdoor views, enhancing the open feel of the space.

Cabin in Clayton

Modern, comfortable, family retreat

You will be close to everything when you stay at this centrally-located, modern retreat. It’s cozy, classy, & perfectly located in a private mtn neighborhood, only one mile away from downtown Clayton's popular restaurants and shopping. From here, you'll be able to enjoy the calm and beauty of the North Georgia mountains, or venture out to Lake Burton, Tallulah Gorge, endless hiking trails, nearby wineries, distilleries & breweries, whitewater rafting, tubing and much more.

4.99 out of 5 average rating, 112 reviews

A green exterior wall of the house is shown, accompanied by a stainless steel gas grill positioned on a spacious wooden deck. Unique shadow play created by tree foliage is visible, adding depth to the scene. A serene lake is seen in the background.

Home in Highlands

Closest to Highlands Main St. And Old Edwards Inn

The closest AirBnB to Main Street in Highlands N.C. The house is on Harris Lake and Main Street is 2 blocks away. This Three Bedroom/two bath house is located a short walk to Sunset Rock and the Highlands Botanical Gardens. Enjoy relaxing in front of a gas fireplace, with numerous comforts of home like, a fully equipped kitchen huge wrap around deck with lake views. All new large screen TV's and updated kitchen and bathrooms. Dog-friendly.

4.97 out of 5 average rating, 172 reviews

A calm lake reflects the surrounding trees and sky, creating a serene atmosphere. On the right, a cabin is visible, partially obscured by greenery. A small dock extends into the water, highlighting the peaceful nature of the location.

Cabin in Highlands

Highlands, NC Authentic Log Cabin w/ Canoe + Dock

Less than 5 minute drive to downtown Highlands + a short canoe ride to On the Verandah restaurant with water access to Lake Sequoyah...Quiet mountain location with beautiful wooded views down to Big Creek. Enjoy the back deck, dock + canoe, and fully stocked kitchen. Completely redecorated with new bedding, towels and art. High chair, bumbo seat and porta crib. Photos and trip ideas at @whittlebearscabin on IG.

4.92 out of 5 average rating, 48 reviews

The spacious living area features high ceilings and exposed wooden beams. Two leather chairs are positioned around a rustic coffee table, with views of the outdoors visible through large windows. A stone fireplace adds a cozy element to the room, complementing the inviting atmosphere.

Home in Clayton

Room at the Top- Pet Friendly Mountain Cabin!

Mountainside cabin with Breathtaking views from every room! Nestled on the side of Screamer Mountain, minutes from town. This property comfortably sleeps 8 and is perfect for families, groups, & couples: incredible game room, fenced yard, and pet area. YouTube TV with Sports Package included. Minutes to downtown Clayton & a short drive to Highlands, Tallulah Gorge, Helen, & Lake Burton.

Vacation rentals for every style

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Popular amenities for Seneca vacation rentals

Self check-in

Gym

BBQ grill

Laptop-friendly workspace

Wifi

Stay near Seneca's top sights

Paesano's Italian Restaurant29 locals recommend

Solé Grill and Sushi Bar27 locals recommend

South Cove County Park19 locals recommend

The Tiki Hut Lakeside Grill12 locals recommend

Keowee Brewing Company31 locals recommend

Lake Keowee Marina16 locals recommend

Other great vacation rentals in Seneca

4.97 out of 5 average rating, 78 reviews

Cabin in Highlands

Beautiful Highlands Cabin: Fun Game Room, Hot Tub

4.85 out of 5 average rating, 20 reviews

A spacious outdoor deck is equipped with a glass-top dining table and blue chairs, surrounded by lush greenery. A vibrant blue umbrella provides shade. In the background, a serene lake is visible, with trees lining the shore and a gentle slope leading to the water.

Home in Fair Play

Bobber Bungalow *level lot*fire pit*kayak*canoe

4.79 out of 5 average rating, 34 reviews

A panoramic view showcases a serene lake surrounded by lush mountains under a colorful sunset. The still water reflects shades of purple and orange, complemented by an expansive sky filled with clouds.

Home in Easley

Jess & Bailey's Easley Escape

4.97 out of 5 average rating, 91 reviews

A wooden dock extends over the calm waters of Lake Hartwell, featuring a platform at the end for boat access. Trees frame the view, providing a natural setting. The sky above is overcast, contributing to a serene atmosphere.

Cabin in Fair Play

Her Redhead Cabin on Lake Hartwell w/ Private Dock

4.83 out of 5 average rating, 24 reviews

An expansive outdoor deck is shown, featuring a comfortable outdoor couch and a gas grill. Scenic views of lush greenery and a tranquil body of water are visible in the background, with rolling hills and a clear blue sky enhancing the serene atmosphere.

Home in Dillard

Big House with Big Mtn Views, Golf & Pool Access

4.89 out of 5 average rating, 91 reviews

A serene cabin is nestled among lush trees, featuring a welcoming porch illuminated by soft lighting. A gentle stream flows over smooth stones in the foreground, surrounded by vibrant greenery, creating a peaceful atmosphere for outdoor relaxation.

Home in Cashiers

10min DWTN Cashiers! 5mn to SilverRun Waterfall

4.95 out of 5 average rating, 83 reviews

Farm stay in Clayton

Mountain house perfect for nature lovers!