
Vacation rentals in Seneca
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Quick stats about vacation rentals in Seneca

Total vacation rentals
Explore 70 vacation rentals in Seneca

Nightly prices starting at
Seneca vacation rentals start at R 821 ZAR per night before taxes and fees

Verified guest reviews
Over 2,520 verified reviews to help you choose

Family-friendly vacation rentals
50 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
70 of Seneca vacation rentals include wi-fi access

Popular amenities for guests
Guests love Gym, BBQ grill, and Laptop-friendly workspace across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated vacation rentals in Seneca
Guests agree: these stays are highly rated for location, cleanliness, and more.

Lake Keowee Waterfront Cottage - Private Retreat
Lake-front retreat w/ unbelievable sunsets, swimming & kayaking, tucked in between the Cliffs & the Reserve, 30 miles west of Greenville. Private park-like setting for a couples getaway. Updated one-bedroom small cottage w/ living room, kitchen, bath, laundry, AC/heat. The entire property is included w/ your cottage rental; 1.1 acres, 800 ft of lake shoreline, a dock, a pier, a sunset deck, a social pavilion, waterfront hot-tub. It is a private lake experience; nothing really compares - unique!

Hartwell Hideway
Escape to this cozy 1-bedroom, 1-bath apartment perched above a private garage on Lake Hartwell. It's just 15 minutes from Clemson University and quaint downtown Seneca. With a full kitchen, cozy living space, on-site parking, keyless entry, and owners nearby, you’ll have everything you need for a relaxing visit. ✔ New build 2024 ✔ Boat access 5 minutes away ✔ Hiking & waterfalls nearby Whether you're here for a Clemson game, a lake adventure, or a quiet getaway, this is the perfect home base.

Treehouse at Keowee Hollow
Welcome to the treehouse at Keowee Hollow!!! A CHARMING space nestled in a hollow - with a view of Lake Keowee - perfect for a ROMANTIC getaway or a peaceful retreat. This COZY, brand new, 1 bedroom, 1 bath treehouse offers rest and relaxation. Perfect location. We are minutes from Seneca, 10 miles from Clemson, under an hour to downtown Greenville, Highlands or Cashiers. The outdoor seating area is a perfect place to unwind at the end of a busy day, also features a fire pit & outdoor grill.

Destination Keowee
A rustic industrial style Lake Keowee lakefront escape that places you right on a panoramic point in a private cove. Welcome the outdoors in with the 6ft kitchen hinge bar window to the upper deck or enjoy the 6-seat hot tub on lower deck. Deep water dock tie off space is available. Guests enjoy the use of 2 standup paddle boards, and lakeside fire pit (guest provide firewood). Great cove sunsets! 15 minutes to Clemson and 1 min Lighthouse Restaurant. Please read all details prior to booking!

Farm Geodome Near Lake Jocassee, Hot Tub, Zip Line
Glamping: where luxury meets the outdoors. This geodesic structure offers a rare opportunity to experience the outdoors without the elements. Complete with kitchen, AC & heat, dual control heated mattress pad, fully functioning bathroom, and sunrise views over the pasture. Whether you are looking to relax and enjoy feeding the farm animals, have an adventure riding the zip line, or indulge in a romantic evening sipping wine in the hot tub under the stars, you will leave with lasting memories.

Clemson Mom Apartment
Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

The Romantic Greystone Cottage
Follow the enchanting stone path to a private getaway where romance and connection await. Enjoy the ambiance of the starlit sky while cuddled up on the hammock or around the fire. Cozy up on the king-size bed and relish every moment of your stay. Indulge in a bottle of wine and relax by soaking in the luxurious claw-foot tub. Wake up to the tranquil sounds of the forest, savoring the morning with coffee on the porch. Escape the everyday and embrace what matters most at The Greystone Cottage.

Cottage in the Country w/ Hot Tub/12mi to Clemson
Relax and unwind at our custom built cottage that provides a peaceful space perfect for 2. This cozy retreat is nestled in the woods in a country setting and offers a deck and hot tub to enjoy the beauty of nature. A dedicated work space is also provided if you're here for work or looking for a place for solitude. It's located only 5 miles from Seneca, 12 miles from Clemson, and 40 miles from Greenville and is a short drive as well to beautiful lakes, waterfalls, and hiking trails.

Lovely 2-bedroom apartment in welcoming Seneca
Seneca is waiting for you at this 2-bedroom minimalist apartment, 15 minutes away from Clemson University. Inside, guests find two queen beds and two bathrooms, each thoughtfully designed for comfort. The space stays comfortable year-round with air conditioning and heating. Whether you're winding down after a day of exploring or starting fresh in the morning, the tranquil invites relaxation. Our place is equipped for both long and short stays, making your holiday one to remember.

Holliday's Inn Tiny Tree-house
Tiny Treehouse is a ‘container’ house set in a private wooded locale at the foothills of the mountains. Find yourself hiking at Oconee State park or Caesar's Head mountain along with a multitude of waterfalls within our county. 5 minutes from downtown historic Walhalla, 10 minutes to city of Seneca, and 20 minutes from Clemson University where tailgaters unite before the big football game! Explore the artistic venues and cultural scenes of Greenville just an hour away!

Oak Hill Getaway
Right between Seneca and Clemson you will find our getaway. It's 5 mins from Historic Ram Cat Alley with shopping, restaurants, and breweries with Jazz on the Alley music every Thursday night (April - Oct.) It's only 10 minutes from Clemson University. Surrounded by 3 different lakes Jocassee, Keowee, and Hartwell with just a short drive away. You can ride 30 mins up to the mountains where you can hike trails and see waterfalls the foothills have to offer.

The Cottage
Relax, recharge, and enjoy the quiet. Unwind on the front porch as the sun sets and nature comes alive with the peaceful sounds of evening. Spend time by the pond and cast a line for a simple, relaxing escape (fishing poles not provided). Private and serene, yet just 5 minutes to Walmart and Oconee Memorial Hospital—and only 13 miles to Clemson. The perfect blend of tranquility and convenience. Minimum age to book is 25 years of age.
Popular amenities for Seneca vacation rentals
Stay near Seneca's top sights
Other great vacation rentals in Seneca

Lake Retreat

Hearth & Pine Cottage | Cozy Nature Escape

Lakeside | 3-Bedroom | 1-Mile from Clemson

The Landing Spot

Valhalla: Cliff-Edge Suite · Forest Views · Tub

South Cove Cottage ~ Lake Keowee

Peaceful Lake Keowee Waterfront Home ~Near Clemson

StellaVista Romantic Treehouse - Waterfall Feature
When is the best time to visit Seneca?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | R 2,445 ZAR | R 2,954 ZAR | R 2,741 ZAR | R 2,527 ZAR | R 3,282 ZAR | R 2,724 ZAR | R 3,053 ZAR | R 3,840 ZAR | R 3,693 ZAR | R 3,184 ZAR | R 3,693 ZAR | R 2,938 ZAR |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 21°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
Frequently Asked Questions
What are the best places to stay in Seneca?
Travelers often stay near Lake Keowee for access to water activities, Historic Downtown for local shops and restaurants, or in the countryside for a quieter experience. Many homes and apartments in these areas welcome visitors looking for both relaxation and recreation.
What are the best things to do in Seneca with kids?
Families can explore local parks, visit playgrounds, or enjoy time by Lake Keowee for swimming and picnics. Educational centers, walking trails, and family-friendly events around town are also frequently suggested.
What are some of the best things to do in Seneca?
Explore Historic Downtown’s boutiques and cafes, relax at Lake Keowee, or visit nearby state parks for hiking and outdoor recreation. Community festivals and farmers markets also add a local touch throughout the year.
How is the weather in Seneca?
Seneca has mild winters around 33–53°F (1–12°C) and warm, humid summers that reach 90°F (32°C). Rain is spread throughout the year, so it is helpful to bring layers and a rain jacket for outdoor plans.
When is the best time to visit Seneca?
Late spring and early autumn are often recommended for comfortable temperatures and colorful scenery. Summer is popular for lake activities, while spring brings local events and blooming landscapes.
What are the best places to visit in Seneca?
Explore Lake Keowee’s shores, browse Historic Downtown’s local shops, or head to South Cove County Park for picnic spots and waterfront access. Cultural centers and museums around town are also frequently suggested.
What are some hiking trails in Seneca?
You will find walking and hiking paths in South Cove County Park and around Lake Keowee. For more variety, nearby state parks are known for scenic trails suitable for most experience levels.
What are some family activities we can do in Seneca?
Families can picnic at local parks, swim or paddle on Lake Keowee, and explore interactive exhibits in community centers. Seasonal festivals and farmers markets often host games, music, and family-friendly vendors.
What are some of the best day trip ideas from Seneca?
Visitors frequently explore nearby state parks for hiking and waterfalls, check out upstate art towns, or tour local vineyards and orchards. Lakes, historic sites, and mountain views are also within easy reach for a full day’s adventure.
Are there any pet friendly accommodations available in Seneca?
Many places in and around Seneca welcome pets, especially those near Lake Keowee or set in rural surroundings. It is helpful to check individual listings for rules on pets and any special amenities, such as fenced yards or easy trail access.
What are some local tips for visiting Seneca?
Try the weekly farmers market for local produce and crafts, and enjoy the lake early or late in the day for quieter moments. Locals appreciate layered clothing due to changing weather and recommend checking for community events during your stay.
What is Seneca known for?
Seneca has a lively lakeside community centered around Lake Keowee, a revitalized Historic Downtown, and access to outdoor recreation in the foothills of the Blue Ridge Mountains. Community events and historic sites reflect the area’s local traditions.
What are the best hidden gems to explore in Seneca?
Many visitors enjoy lesser-known parks, local art galleries, and specialty shops tucked away in Historic Downtown. Quiet coves along Lake Keowee and nearby heritage museums also draw those seeking unique local experiences.
What are the best foods to try in Seneca?
Seneca has locally rooted Southern cuisine, with dishes like barbecue, fried catfish, and homemade pies often recommended. Seasonal farmers markets around the area feature regional produce and handmade treats during parts of the year.
What should I bring for a trip to Seneca?
Pack layers for changing temperatures, a rain jacket for unexpected showers, and comfortable shoes for outdoor activities. A swimsuit, sun protection, and reusable water bottle are helpful for time by the lakeshore or on trails.
What is the nightlife in Seneca like?
Seneca’s nightlife features casual bars, local pubs, and live music venues around Historic Downtown. Events and open-air concerts bring residents and visitors together during warmer months.
What are the most popular events or festivals in Seneca?
Seneca hosts seasonal festivals, including downtown music events, local fairs, and outdoor concerts, especially in the warmer months. Community celebrations around Memorial Day and late spring are frequently highlighted by locals.
Are there family friendly vacation rentals in Seneca?
Seneca has a range of family-friendly rentals, including lakefront homes and properties in quiet residential neighborhoods. Many include amenities such as full kitchens, multiple bedrooms, and outdoor spaces for children to play.
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- Clemson University
- Black Rock Mountain State Park
- Gorges State Park
- Table Rock State Park
- Tallulah Gorge State Park
- Helen Tubing & Waterpark
- Bell Mountain
- Devils Fork State Park
- DuPont State Forest
- Bon Secours Wellness Arena
- Unicoi State Park and Lodge
- Ski Sapphire Valley
- Fred W Symmes Chapel
- Chattooga Belle Farm
- Jump Off Rock
- Looking Glass Falls
- Dillard House Restaurant
- Fluor Field at the West End
- Anna Ruby Falls
- Peace Center
- Jones Gap State Park
- Falls Park On The Reedy
- Dry Falls
- Carl Sandburg Home National Historic Site





