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Vacation rentals in Santiago Canyon

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santiago Canyon

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Private room in Mission Viejo
4.96 out of 5 average rating, 113 reviews

Private room with hot tub!

Private suite with its own entrance. Queen size bed, desk, high-speed internet, small fridge, microwave, your own full bathroom, and outdoor patio seating by the pool. Guests are welcome to use the pool during the summer (not-heated) and hot tub year round. We have beach chairs, umbrella, towels, and mini cooler available. We're only 14 miles to Laguna Beach, close to John Wayne Airport (SNA), and 26 miles to Disneyland. Neighborhood park close by. Mission Viejo STR Tax Certificate #P000059

Guest favorite
An open living space is highlighted by a spacious sofa, an inviting coffee table, and natural light streaming through large windows. A modern kitchen with bar seating and a dining table is visible in the background, creating a seamless flow for relaxation and dining.
Guesthouse in Trabuco Canyon
4.99 out of 5 average rating, 74 reviews

Farmhouse - 360° Nature Views in Trabuco Canyon

Escape to tranquility in Trabuco Canyon, CA. This fully-renovated two-bedroom, one-bath retreat offers a full kitchen, large patio with propane grill, fire pit, Adirondack chairs, and a laundry room. Surrounded by nature, it’s located on a working farm with chickens and fruit trees. Walk to the historic Cook's Corner Bar, enjoy breathtaking hiking trails, scenic drives, & beautiful restaurants - even a local winery. Guests have full access to the house and patio. Book your nature retreat today!

Superhost
A cozy living room features a plush, oversized sofa adorned with decorative cushions. A wooden coffee table sits at the center, complemented by an accent chair. Natural light filters through large windows, and decorative shelving displays plants and curated items against a patterned wall.
Home in North Tustin
4.84 out of 5 average rating, 541 reviews

Designer Hilltop House Getaway, VIEWS + Disneyland

High Above the city lights, a perfect place to rest for the night. Wake up to a serene sight, open your eyes to new heights. Near: Disneyland Orange County John Wayne Airport SNA Long Beach Airport LGB Los Angeles Airport LAX Ontario Airport ONT Orange Beaches, Shopping Chapman University U C Irvine The Pond The Ducks Newport Beach Tustin Long Beach Little Saigon Fashion Island Westminster Garden Grove Santa Ana Fullerton Riverside *Designated Driveway Parking only. NO neighborhood parking.

Top guest favorite
The Cottage of Whimsy is framed by lush greenery and towering oak trees. Sunlight filters through the glass windows, illuminating the white exterior and showcasing the unique stone foundation beneath. The inviting environment hints at tranquility and a connection to nature.
Guesthouse in Ontario Ranch
4.98 out of 5 average rating, 129 reviews

Studio Ghibli Cottage of Whimsy in Beautiful Trees

The Cottage of Whimsy is a small and adorable Studio Ghibli-themed studio built in the early 1930s, lovingly renovated in 2021. Whether you're an artist looking for a nourishing creative retreat, a couple looking for a peaceful getaway, or a small family eager for a restorative escape to sunny Southern California, the Cottage of Whimsy is for you! With views of 100-year-old oak trees, the sounds of chickens clucking and horses clopping, and walking distance from 4,500 acres of scenic trails!

Guest favorite
The entrance to a charming villa is framed by tall trees and a clear blue sky. A paved driveway leads to the house, which features a terracotta roof and white walls. Decorative plants and a vintage green tractor add character to the welcoming exterior.
Home in Ontario Ranch
5 out of 5 average rating, 17 reviews

Casa Bella

Casa Bella is a hidden gem nestled in the picturesque foothills of Orange County on the Rancho Las Lomas private estate and event venue. This charming and tranquil Villa is two-bedroom, one-bath house with a full kitchen, large patio with bistro lights, serene fountain area and pergola outdoor dining. This enchanting retreat is surrounded by hiking trails, scenic drives and historic establishments. Guests have exclusive access to the house and patio during their stay. Book your getaway today!

Top guest favorite
A spacious living area is complemented by tall ceilings and ample natural light from large windows. Comfortable seating is arranged on a multi-colored sofa, and a wooden dining table is visible in the background, accompanied by a variety of plants.
Private room in Tustin
4.86 out of 5 average rating, 217 reviews

Healthy & Cheerful home.

Bedroom is 2 steps from front door. 😊 Large home with lots of windows and a happy vibe. You will feel comfortable. Mini Fridge in room. The dog in the photo does not live here, but there is a couple of outside/ inside cats. Very quiet neighborhood. There are 2 Private heated pools to enjoy. You can check in as late as you like. Wonderful park to walk, 1 minute away. We are 1 mile from Old Town Tustin, which is a wonderful are to walk, shop, dine & the greatest French Bakery in California!

Top guest favorite
A modern home is positioned on a hillside, showcasing a large driveway and an expansive patio. The panoramic view of Orange County is visible, with residential areas and green spaces stretching into the distance under a partly cloudy sky.
Home in Santa Ana
4.9 out of 5 average rating, 220 reviews

360° HILLTOP VIEW / Ultra Modern / 15min DISNEY

Enjoy 4000 sq ft of spacious modern architecture, tons of amenities for large groups *KEY FEATURES* + Epic panoramic view of Orange County + Floor-to-ceiling glass walls + Indoor/outdoor living - every glass wall opens fully to the patio + Fully stocked kitchen + Top quality memory foam beds, gel pillows, and sheets + Speedy wifi (100↓, 20↑) + TVs w/ HBO Max, Netflix, Amazon Prime, Disney+, Hulu *LOCATION* + 15 min to Disneyland + 18 min to Knotts + 20 min to the beach + 15 min to Outlets

Superhost
A bright living area features large windows that provide views of lush greenery. A comfortable sofa is centered around a decorative coffee table, accompanied by two small metal chairs. Soft carpeting and tasteful decor create a cozy and welcoming environment.
Guest suite in Santa Ana
4.82 out of 5 average rating, 94 reviews

Adorable 1 bedroom with cozy fireplace and balcony

Unwind in this beautiful and serene and 1 bedroom apartment. Located in North Tustin on a private estate surrounded by mature trees and gorgeous landscaping. Designed with the charm and comfort of a Tuscan villa while still being conveniently located in Orange County. The perfect little retreat complete with everything you'll need for a comfortable stay. Near: *Disneyland *Knotts Berry Farm *5 & 405 fwy *Irvine Spectrum *Long Beach *Newport Beach *Huntington Beach *LAX *Ontario Airport

Top guest favorite
A light-filled studio features a spacious bed adorned with striped bedding and coordinating pillows. A small dining table with two chairs sits nearby, complemented by a textured area rug. A tall white wardrobe provides storage, while natural light filters through the window.
Guest suite in Mission Viejo
4.97 out of 5 average rating, 193 reviews

Centrally located private mission viejo studio

Just 3 minutes from the 5 freeway sits this attached but private studio. Once through your private entrance you will feel at home. Comfortable queen bed, fireplace and fully stocked kitchenette with mini fridge/ freezer if you feel like cooking. There is also a 2 person table/ desk in front of the warm electric fireplace. The ceiling fan keep things cool. Full bathroom with shower and bathtub. Salt Creek beach,Dana Point Harbor and Trestles are just 15-20 minutes away. Great Location!

Top guest favorite
A charming cottage exterior is shown, featuring a welcoming red door framed by two windows. A stone path leads to the entrance, surrounded by a gravel area and lush green grass. Nearby, natural landscaping includes trees and a wooden fence.
Guesthouse in Ontario Ranch
4.97 out of 5 average rating, 131 reviews

Orange County Country Cottage

Get out of the city and come spend a night in this relaxing 1 bedroom cottage in the hills of Orange County's Trabuco Canyon. Our little cabin has a queen bed, couch, small table & chairs for dining, bathroom with shower, small kitchenette with microwave, refrigerator, & Keurig coffee maker. Hike right out of the backyard to miles of trails with beautiful mountain views, wildlife, seasonal creeks or 2 of OC's best kept secrets for dinner Rose Canyon Cantina & Trabuco Oaks Steakhouse.

Top guest favorite
A charming outdoor area features two gray chairs positioned near a stone walkway leading to the entrance. Potted plants add greenery alongside the house, which is surrounded by a white picket fence. The space is bathed in natural sunlight.
Tiny home in Orange
4.93 out of 5 average rating, 502 reviews

Cozy Cottage on Horse Property!

This Cottage is a unique space on a beautiful equestrian property! Space offers a comfy bedroom and spacious bathroom....240 SQ FT!! Minutes from the 5/55/91 freeway and Only 8 miles away from Disneyland and Anaheim Stadiums! Only 20 mins to Newport /Laguna Beach. $40 additional cleaning Fee for one pet due prior to check in.,...2 pets would be considered with additional fee to be determimed by me .... which would be related to length of stay.message me in regards to this matter.

Top guest favorite
Private room in Cowan Heights
4.95 out of 5 average rating, 174 reviews

2 Bed+1Bath+Private Entrance & Close to Disneyland

2-bedroom, 1-bathroom Arbnb nestled in a peaceful residential neighborhood. Step inside your own private entrance to find bright and spacious rooms with luxury 100% cotton linens. The large backyard features a patio where you can sit and relax while sipping on your morning coffee by the pool. The bedrooms are generously sized and the main bedroom has an efficiency that includes a coffee maker, toaster, microwave, water kettle and refrigerator. This Airbnb is your perfect sanctuary.

Popular amenities for Santiago Canyon vacation rentals