Vacation rentals in Santee

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Top-rated vacation rentals in Santee

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Guest favorite
Condo in Santee
4.96 out of 5 average rating, 95 reviews

Lovely Condo w/pool, balcony, and lakeside view!

Relax on the balcony overlooking the pool and lake Marion or go down and relax at the pool, or launch your boat at the boat ramp for the day and go fishing or cruising. There is also a myriad of golf courses near by. For dinner with a great view head over to the other side of the lake to the Lake House bar and grill for adult beverages on the lake with great food. For upscale dining Clark’s restaurant is a good choice. Bike,hike,or cook out over at Santee state park which is only 10 minutes away

Top guest favorite
The rustic cabin features weathered wooden siding and a metal roof partially covered by overhanging branches. A front porch with railings leads to a small entry door, surrounded by grass and shrubs. The serene natural setting complements the cabin's quaint charm.
Cabin in Rowesville
4.95 out of 5 average rating, 206 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Top guest favorite
A serene view from a screened porch is shown, featuring two wooden rockers facing the tranquil lake. Green grass and trees surround a private dock visible in the distance, creating a peaceful outdoor setting.
Cottage in Manning
4.97 out of 5 average rating, 133 reviews

Archie's Lake Daze Cottage No pets

Soak up the beautiful lake views from a rocker on the porch or the 2-person hammock between the pine trees. This cozy cottage has 3 BR and 2 Baths and a stocked kitchen to make you feel right at home. Enjoy fishing from your private dock or take a spin in the paddle boat or kayaks provided. After a long day on the lake, you can enjoy a game of pool, classic arcade games, darts, or board games. WiFi is provided as well as 3 smart TVs. There is plenty of parking for your vehicles and water toys.

Guest favorite
A charming log home is set on a grassy lot, surrounded by trees. The façade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.
Cabin in Vance
4.9 out of 5 average rating, 242 reviews

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Guest favorite
Cabin in Saint Matthews
4.78 out of 5 average rating, 188 reviews

A relaxing cabin on private pond. Old Bells Secret

Escape to our secluded cabin on 90 acres in St. Matthews, SC! This early 2000s style cabin features 2 cozy bedrooms, 1 bathroom, and a lovely porch. The large pond is perfect for swimming, fishing, or playing. It’s an endless adventure. The house can sleep up to 6 with the pull out couch. Accessible via a private road, it's perfect for weekend getaways with the family or housing for workers. Experience relaxation and adventure in nature at this wonderful cabin. Book now for a memorable stay!

Top guest favorite
A spacious covered deck provides views of the lake through large trees, featuring two striped chaise loungers and a dining table with four chairs. The wooden flooring enhances the outdoor space, inviting relaxation and enjoyment of the serene surroundings.
Guest suite in Eutawville
4.81 out of 5 average rating, 103 reviews

Relaxing Comfortable Waterfront Family Dock Suite

Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

Guest favorite
A scenic view of the lake is presented, featuring a long dock extending into the calm water. Lush greenery and palm trees frame the foreground, while a faint rainbow appears in the backdrop under a partly cloudy sky.
Home in Santee
4.96 out of 5 average rating, 173 reviews

Stylish Lakefront Group Getaway Sleeps 8

Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

Top guest favorite
Cottage in Sumter
4.97 out of 5 average rating, 513 reviews

Restful Lakeside Cottage -Dogs allowed

This pond-side cottage is a peaceful place to relax & unwind. Sit in the sunroom and enjoy watching the birds & the water or enjoy the front porch rockers where you can listen to the birds & frogs. We are 12 min. from downtown Sumter & 20 min from Shaw AFB. Local points of interest are Swan Lake Iris Gardens & Poinsett State Park. It is only 2 hrs to Myrtle Beach and Charleston, SC & 3 hrs to the mtns. While it is conveniently located, this cottage offers a quiet place to relax.

Guest favorite
An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.
Home in Santee
4.96 out of 5 average rating, 179 reviews

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Top guest favorite
A spacious deck overlooks a serene cove, featuring a dining table surrounded by six chairs. Lounge seating is positioned nearby, inviting relaxation. Lush trees frame the area, with views of water and nearby boats visible, creating a calm retreat.
Home in Summerton
4.99 out of 5 average rating, 128 reviews

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Superhost
An outdoor balcony features a dining table surrounded by four mesh chairs. A ceiling fan is visible above, and the view includes a serene lake framed by trees under a clear blue sky.
Apartment in Santee
4.85 out of 5 average rating, 34 reviews

Relaxation is the plan

Come and relax in this peaceful retreat. A beautiful view of the lake and the sunset from the comfort of the living area or outside on the spacious balcony, a stunning lakefront property offering breathtaking views. This meticulously maintained 2-bedroom, 2-bathroom condo is centrally located off I-95, providing both privacy and convenience. The serene lake views and well-kept interiors create a peaceful retreat for relaxation.

Superhost
A spacious living area features a sectional sofa, a coffee table, and an area rug. The dark accent wall is adorned with framed art. A smart TV is mounted above a modern fireplace. A dining table for four is visible in the background, leading to the kitchen.
Condo in Santee
4.91 out of 5 average rating, 46 reviews

Sunsets on Lake Marion: 2BD Lakefront Luxury Bliss

Introducing your lakeside sanctuary at Lake Marion! This carefully renovated 2 BR, 2 BA condo boasts sweeping lake vistas, fresh LVP flooring, modern lighting, and charming accent walls. Delight in lakeside grilling or venture out for aquatic fun with direct lake access. An hour away from Charleston and Columbia, surrounded by shopping, dining, and golf options, this retreat offers the best of relaxation and adventure.

Popular amenities for Santee vacation rentals

When is the best time to visit Santee?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceR3,853 ZARR3,985 ZARR4,200 ZARR4,184 ZARR4,118 ZARR4,564 ZARR3,870 ZARR4,581 ZARR4,730 ZARR4,796 ZARR4,564 ZARR4,697 ZAR
Avg. temp10°C12°C15°C19°C23°C26°C28°C27°C25°C20°C15°C11°C

Frequently Asked Questions

  • What are the best places to stay in Santee?

    Staying near Lake Marion, in local neighborhoods, or close to community parks is frequently suggested for convenient access to outdoor activities. Waterfront rentals or homes with nature views are popular among groups and families seeking a peaceful retreat.

  • What are the best things to do in Santee with kids?

    Kids can enjoy fishing from piers, playgrounds in area parks, and learning about local wildlife at visitor centers. Boat rentals, gentle trails, and open fields create space for exploration and outdoor play.

  • What are some of the best things to do in Santee?

    Spend time exploring Santee State Park, go fishing or boating on Lake Marion, or enjoy birdwatching in nature reserves. Local golf courses and small-town restaurants add activity options for all interests.

  • How is the weather in Santee?

    Santee has mild winters around 39–60°F (4–16°C) and humid, warm summers near 74–91°F (23–33°C), with the wettest months in midsummer. Spring and fall bring comfortable temperatures and are popular seasons for outdoor activities.

  • When is the best time to visit Santee?

    Late spring and early fall are often recommended for milder weather, with temperatures typically from 63–84°F (17–29°C) in May and 58–78°F (14–26°C) in October. These seasons bring blooming plants and less humidity, making outdoor activities inviting.

  • What are the best places to visit in Santee?

    Santee State Park, Lake Marion, and area wildlife refuges are often recommended for visitors interested in nature and recreation. Local craft shops and smaller museums add cultural depth to your visit.

  • What are some hiking trails in Santee?

    Explore gentle trails in local parks or the Santee State Park, which has routes through pine forests and along the lake’s edge. Boardwalks and shorter nature paths make it welcoming for hikers of various experience levels.

  • What are some family activities we can do in Santee?

    Families can experience fishing and boating on local lakes, play at community parks, or visit nearby wildlife centers for interactive learning. Picnicking areas and gentle trails are frequently suggested for outdoor fun together.

  • What are some of the best day trip ideas from Santee?

    Around Santee, you can explore wildlife refuges, historic small towns, or scenic lakes for boating and fishing. Regional gardens and nature reserves are often recommended for those looking to enjoy local flora and tranquil settings.

  • Are there any pet friendly accommodations available in Santee?

    Santee has a variety of pet-friendly places to stay, especially in areas near lakes and parks. Many local accommodations welcome pets, making it easier for visitors traveling with companion animals.

  • What are some local tips for visiting Santee?

    Locals often encourage exploring nature early in the day to avoid peak heat, and sampling regional seafood or barbecue from family-run spots. Keeping a refillable water bottle handy is practical for outings in the warmer months.

  • What is Santee known for?

    Santee is known for its scenic lakes, freshwater fishing, and outdoor recreation. The area has golf courses, birdwatching sites, and is recognized as a welcoming base for exploring natural and cultural attractions throughout the region.

  • What are the best hidden gems to explore in Santee?

    Santee has serene natural spots like quiet lakeshores, birdwatching areas, and smaller local parks that invite gentle exploration. Discover less-trafficked trails, unique local eateries, or art spaces often appreciated by those seeking a laid-back atmosphere.

  • What are the best foods to try in Santee?

    Regional favorites often include fried catfish, slow-cooked barbecue, and seasonal Southern vegetables. Locally made desserts and sweet tea provide a taste of the area's culinary traditions.

  • What should I bring for a trip to Santee?

    Pack lightweight clothing for warm days, a light jacket for cooler evenings, and comfortable footwear for walks. Bringing sunscreen, bug protection, and a hat is frequently suggested, especially for outdoor exploration or water activities.

  • What is the nightlife in Santee like?

    Nightlife in Santee is mellow, with social settings like local restaurants, bars, and casual gathering spots centered around food and conversation. Some venues host live music or special events on weekends, creating a friendly atmosphere.

  • What are the most popular events or festivals in Santee?

    Santee hosts community festivals during early fall and spring, often centered around local food, live music, and outdoor recreation. Fishing tournaments on Lake Marion are a highlight for those interested in angling competitions.

  • Are there family friendly vacation rentals in Santee?

    Santee has many family-friendly vacation rentals, especially properties around lakes or in quiet neighborhoods. Look for homes with spacious living areas, kitchens, and access to outdoor spaces for relaxed group stays.

Quick stats about vacation rentals in Santee

  • Total vacation rentals

    Explore 30 vacation rentals in Santee

  • Nightly prices starting at

    Santee vacation rentals start at R1,654 ZAR per night before taxes and fees

  • Verified guest reviews

    Over 230 verified reviews to help you choose

  • Family-friendly vacation rentals

    20 properties offer extra space & kid-friendly amenities

  • Vacation rentals with a pool

    20 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    30 of Santee vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Self check-in, Gym, and BBQ grill across Santee rentals

  • 4.7 Average rating

    Santee stays receive an average rating of 4.7 out of 5 from guests