Vacation rentals in Orangeburg County

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Top-rated vacation rentals in Orangeburg County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
The bedroom features a spacious bed dressed in white linens with red accents. A desk with dual monitors is positioned next to the bed. A dresser and a soft area rug add warmth, while natural light filters in through a window with light drapes.
Home in Orangeburg
4.95 out of 5 average rating, 38 reviews

Theo's Place

Kick back and relax in this calm, stylish space. I'm happy to offer my 1st home as a host, providing all the amenities I've wanted as a guest in my years of successful stays on the AirBnB platform as a guest (laptop not included). My guest will find various comforts and additions to make their stay as comfortable as can be. I welcome your feedback. My home is available as a 1 Bedroom with a large Den, Living & Dining rooms, 2 Bathrooms, full Kitchen and Laundry room. All new appliances as well.

Guest favorite
The rustic cabin features weathered wooden siding and a metal roof partially covered by overhanging branches. A front porch with railings leads to a small entry door, surrounded by grass and shrubs. The serene natural setting complements the cabin's quaint charm.
Cabin in Rowesville
4.95 out of 5 average rating, 176 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Top guest favorite
A single-story brick ranch home is set in a green, well-maintained yard. A large palm tree is situated near the entry, with a few steps leading up to the front door. The front porch features two rocking chairs, enhancing the welcoming appearance of the home.
Home in Orangeburg
5 out of 5 average rating, 64 reviews

Trendy, cozy and casual

Total Renovation of 1235 square feet brick ranch with 1 car garage, screened in back porch and large fenced back yard. 2 baths, updated fully equipped kitchen, dishwasher, new floors, curtains & linens. Roku TV, wireless internet. Washer and Dryer Pet Notes: Pets have to be approved in advance of stay and pet fees will be charged per pet. Pets are welcome but there is a pet fee based on number of dogs and breed. Some breed are restricted by insurance company. Contact me before booking please.

Guest favorite
A charming log home is set on a grassy lot, surrounded by trees. The façade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.
Cabin in Vance
4.89 out of 5 average rating, 201 reviews

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Top guest favorite
A spacious living area features a large blue sectional sofa adorned with patterned cushions. A light wooden coffee table sits on a soft area rug, complemented by a small potted plant. Natural light filters through the windows, creating a bright and welcoming environment.
Home in Orangeburg
5 out of 5 average rating, 132 reviews

The Grand Marshall

Bring the whole family to this renovated 3 BR, 2 bath home +1 BONUS ROOM, which serves as a theatre/game room with 2 queen sleeper sofas. Your family will enjoy: Coffee/beverage/snack bar Central location: Approximately 5 minutes to SC State and Claflin University, OC Tech College, Edisto Gardens, MUSC Health Orangeburg, shopping, dining, and more. Designated office space 1 king bed, 2 queen beds, plus 2 queen sleeper sofas 5 Roku Smart TV’s Smart lock for easy access High speed WiFi

Guest favorite
An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.
Home in Santee
4.97 out of 5 average rating, 143 reviews

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Superhost
An outdoor seating area features two high chairs and a small table, positioned on a concrete patio. The serene pond is visible beyond a wooden railing, surrounded by lush greenery, inviting a tranquil atmosphere for relaxation.
Tiny home in Orangeburg
4.76 out of 5 average rating, 21 reviews

Tiny Pond House

Reconnect with nature at this unforgettable escape. The best part of our pond cabin is the view! The outdoor space can be utilized to take in fresh air and escape the busyness of life and far outweighs the tiny square footage. Escape, relax and enjoy your home away from home. Our home is meant for one to two people to have a cozy, minimalistic experience but comes with all the amenities. All are welcome to use of the pond , so feel free to bring your fishing rods & tackle.

Guest favorite
The exterior of the home features a modern architectural design with large windows and a spacious deck. An inviting infinity pool is illuminated, reflecting the colorful sunset. A comfortable outdoor seating area surrounds a fire pit, creating a serene lakeside atmosphere.
Home in Summerton
4.92 out of 5 average rating, 119 reviews

Ultimate Lake Marion Dream Home W/Pool & Swim Spa

Welcome to The White House—a stunning lakefront retreat on Lake Marion. This luxurious home features 4 spacious bedrooms, 3.5 baths, a chef’s kitchen, private dock, gas grill, and HDTVs throughout. Relax in the infinity pool or unwind in the swim spa as you take in the tranquil views. The master suite is a true sanctuary, offering unmatched comfort and elegance. Hosted by Lake Marion Luxury Vacations, this home is your gateway to peace, luxury, and unforgettable memories.

Top guest favorite
An A-frame structure is pictured, elevated on a brick foundation. Sturdy wooden stairs lead to the entrance, flanked by a deck with railings. The surrounding area is filled with tall trees, and a car is parked underneath the apartment, offering a rustic country setting.
Apartment in Orangeburg
4.99 out of 5 average rating, 131 reviews

Elevated Country Apartment

Discover the charm of country-living in our cozy 1-bedroom elevated apartment, just a short drive from Orangeburg, Bamberg, and Neeses. Wake up to the sound of roosters crowing and enjoy your morning coffee with views of our picturesque homestead, or enjoy a glass of wine while watching the sun set below the majestic pines. Perfect for those seeking tranquility without sacrificing convenience, our apartment offers a fully-equipped kitchen and laundry.

A spacious living area showcases an exposed brick wall, enhancing the room's character. Mid-century modern furniture includes a sleek sofa, two stylish chairs, and a round coffee table atop a textured rug. Natural light fills the space through large windows with blinds, creating a warm atmosphere.
Apartment in Elloree
5 out of 5 average rating, 6 reviews

Spacious stylish 1 bedroom loft

Spacious one bedroom loft features a captivating blend of exposed brick, soaring ceilings and tastefully curated contemporary art amidst a collection of comfortable mid century modern furniture. Just a few steps from the stores and restaurants on Cleveland Street, a short walk away from tennis courts in Joe Millers Park and only 10 minutes by car from Santee State Park, Lake Marion, and three golf courses.

Top guest favorite
A spacious bed is dressed with a light patterned duvet and decorative pillows. A black nightstand is positioned beside the bed, topped with a textured lamp and a small potted plant. The backdrop features green wainscoting, adding a calming touch to the room.
Apartment in Barnwell
4.99 out of 5 average rating, 115 reviews

Ellzey Place

Ellzey Place is a peaceful spot where you can relax and unwind. Enjoy having a cup of coffee on the deck facing a spacious private back yard. There are lots of azaleas that bloom in season and pines swaying in the breeze. It is a charming apartment attached to the owner's house but has a private deck and entrance. It has been newly remodeled and delightfully decorated.

Superhost
A quaint cottage is nestled among trees, showcasing a wooden façade and a sloped roof. A hammock rests on the side, inviting relaxation. Rocking chairs are placed on the porch, while a white door leads into the interior. Natural light filters through the greenery.
Tiny home in Blackville
4.89 out of 5 average rating, 151 reviews

Spanish Moss (Carolina Cottage)

Enjoy the sounds of nature when you stay in this unique place. Wildlife, Magnolia’s, trees, Spanish Moss draped 200 year old Oak trees, Pecan Orchard Views. Private gated drive to cottage. The Bungalow at Magnolia is located on the same property which does not allow pets 120 feet distance wooded unable to see cottages from each other. 420 friendly property.

Popular amenities for Orangeburg County vacation rentals