Vacation rentals in Pine Island

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Top-rated vacation rentals in Pine Island

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A garden-level apartment is accessed via a gravel driveway that leads to a charming home. Lush greenery surrounds the path, and the structure features a mix of siding colors, with large windows framed by blue shutters, creating an inviting exterior appearance.
Apartment in Rochester
4.93 out of 5 average rating, 210 reviews

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

Top guest favorite
A welcoming living room features a plush brown sofa adorned with decorative pillows, complemented by a wooden coffee table. Natural light pours through the large window, illuminating the space. A potted plant and two stylish lamps add character to the cozy environment.
Home in Rochester
5 out of 5 average rating, 73 reviews

New! MN Comforts The Heart 4Bd/2Bth, 12min to Mayo

Welcome to MN Comforts The Heart! Are you here for work or leisure, or want to feel comforted after a Mayo appts? 12 min to Mayo Clinic, Wifi, work-station, ROKU/Smart TVs, and a fireplace in the family room. We offer a 2nd home feel. Near stores. Split-level, chill, and quiet, thoughtfully designed to cater to your needs, ensuring a comfortable, enjoyable stay. A blend of traditional & modern styling in a tranquil home, with fun opportunities for family & friends. Partially fenced backyard.

Guest favorite
A dining area features a long wooden table surrounded by black chairs. Natural light enters through multiple windows, illuminating a light-colored wall with artwork. A cozy nook with built-in seating and a vase of yellow flowers adds charm to the space.
Home in Zumbrota
5 out of 5 average rating, 6 reviews

4BR Modern Home, Hot Tub, Fire Table & Family Room

Discover your perfect family/group retreat: *beautifully remodeled farmhouse *nestled directly across from the Zumbrota Golf Course *sleeps 9 guests 4 queen bedrooms | single bed in family room *relax in the cozy living room *family room on the 3rd floor *hottub, expansive deck, and enclosed screened in porch *30 min to Rochester(Mayo Clinic, Apache Mall, and more) *Approx 1 hour to the Twin Cities (Minneapolis & St. Paul), offering major attractions, sporting events, and cultural experiences.

Top guest favorite
A serene view of a well-maintained lawn leading to a calm lake, framed by trees. A stone-edged garden bed with varied foliage is visible in the foreground. The water glistens under sunlight, and a dock is seen in the distance, enhancing the peaceful lakeside setting.
Home in Zumbro Falls
4.97 out of 5 average rating, 32 reviews

Zumbro Lake Home

Relax with the whole family, plan an ice fishing trip with your buddies, or enjoy the lake between clinic appointments. Large lawn with 160ft lake front perfect for swimming, kayaking, fishing, or just relaxing by the water. Full kitchen, laundry, 2 full bathrooms, 2 bedrooms, 2 queen beds and twin bunkbeds in the main house. A second, separate building referred to as the "Bunkhouse" features 3 double beds upstairs and a 2 double beds in the lower level. Within 20 minutes of the Mayo Clinic.

Superhost
A spacious living room is showcased, featuring a large dark sectional sofa with a light throw blanket. A television unit stands against one wall, while a small table with decor is positioned beside a chair. Soft lighting creates a cozy ambiance.
Apartment in Byron
4.75 out of 5 average rating, 12 reviews

Calm & Comfort | 12 Min to Mayo

- Enjoy a peaceful and private lower-level apartment 12 MINUTES TO MAYO -A spacious living room & bedroom, convenience station, plus a full bathroom with a relaxing shower -This stylish place has ample storage and Private entrance. Please note: your host lives on the upper level, but your space is completely private and secure, with host available if you need anything. - Whether you’re here for medical visits or a getaway, this home provides the perfect balance of comfort and convenience.

Top guest favorite
A spacious bedroom features original hardwood floors and a large window allowing natural light. A comfortable bed with a plaid duvet is positioned alongside a wooden dresser. A rocking chair sits in the corner, adding a cozy touch to the room.
Home in Kasson
4.96 out of 5 average rating, 130 reviews

Home Sweet Minnesota

A few days or a few weeks away from home? Let us provide a comfortable and cozy get away in this turn of the century, two story home. Located in a quiet neighborhood with off-street parking, this property boasts large rooms, original hardwood floors and woodwork, a full kitchen, and laundry. The large, fenced in backyard, complete with playground and sandbox, makes this a child friendly space. The front porch and back patio provide outdoor room to grill, picnic, or just relax in a lawn chair.

Top guest favorite
A cozy seating area features a gray sofa and two armchairs with decorative cushions. A round coffee table sits in the center, accompanied by a plush area rug. A large TV displays a calming nature scene, while soft natural light filters through sheer curtains.
Home in Rochester
4.93 out of 5 average rating, 273 reviews

Home Calls the Heart- 10min to Mayo

1/2 block from HWY 52, serene and peaceful split level home. 10 min to Mayo Clinic & St. Mary's Hospital. Fully furnished, convenient and ideal for families and professionals for the home away from home feel. Luxury Sheets & Posturepedic beds. Reasonable Mall of America drive. Fully equipped with various kitchen appliances and utensils. Minutes to parks, groceries, Walmart, Target etc. Wifi, Roku Smart TV & cable. Phone call away if you have any issues while staying at our charming home.

Top guest favorite
A welcoming book titled 'Welcome to Oasis' is displayed prominently, featuring a lotus flower design and neatly placed beside a decorative white vase. Greenery is visible in the background, adding a touch of nature to the inviting setting.
Home in Rochester
4.94 out of 5 average rating, 122 reviews

Oasis - Comfort & Serenity (Full house near Mayo)

*Discount for extended stays* Seeking a peaceful respite near Mayo Clinic in Rochester, MN? Look no further than "Oasis"–your ultimate home away from home. We offer 5 beds, 2 baths, & can accommodate up to 8 guests. Recharge in the workout & yoga meditation room, stay connected in the office area, & explore Rochester's attractions. Your dedicated host Peggy, a Mayo employee, will ensure a seamless/enjoyable stay. Book now & experience the perfect blend of comfort & serenity at Oasis.

Top guest favorite
A cozy living room space features a beige couch adorned with decorative pillows and a low coffee table. The white brick wall serves as a backdrop for a fireplace, which is framed by a wooden mantle decorated with artwork and a wreath. Natural light enters through a window.
Apartment in Rochester
4.97 out of 5 average rating, 258 reviews

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

Top guest favorite
A modern home features a light-colored exterior with stone accents. The front entrance is marked by a wide staircase leading to double doors. Lush green grass surrounds the driveway, which leads to a two-car garage. A tree stands nearby, enhancing the outdoor space.
Home in Rochester
4.92 out of 5 average rating, 127 reviews

St. Augustine’s Family Home ❤️ GARAGE!!

Wonderful clean, newer home located in the fast growing NW Rochester. The home is the perfect set up for large families. 2 bedrooms and 2 bath located upstairs on main level, 2 bedroom and bath located downstairs. An air mattress is optional for additional sleeping. The home is well equipped, comfortable, and clean. Smart Tv and fast WiFi!!! 2 car garage and snow service included!! Restaurants, playgrounds, salons, bars, breweries, movie theatre, and shopping minutes away!!

Top guest favorite
The spacious living area features a contemporary sofa adorned with colorful cushions. A mid-century coffee table is centered on a soft rug, while a modern chair and decorative artwork complement the space. Natural light pours in through sliding glass doors, enhancing the inviting atmosphere.
Guesthouse in Rochester
4.97 out of 5 average rating, 249 reviews

Hygge House | A Cozy Guesthouse

The Hygge (pronounced hyoo·guh) House is a tiny taste of Scandinavia in Southeastern Minnesota. What is Hygge? In short, it's a Scandinavian way of living that focuses on hunkering down and creating a safe, comforting and warm place to while away. My husband and I hand built the Hygge House with your comfort in mind. We love being cozy and having space to spend together so when the opportunity arose to renovate our studio, we wanted to share it!

Guest favorite
Apartment in Rochester
5 out of 5 average rating, 6 reviews

Viola Suite #1 | 1 bed, 1.5 Bath, Pets Welcome

Spacious, pet-friendly home less than 3 miles from Mayo Clinic downtown campus! Features a king bed with attached workspace, 1.5 baths, cozy living room with smart TV, dining area, and full kitchen. Easy access with only 2 steps to enter and no steps inside. Enjoy the large shared yard, coin laundry, and free off-street parking. Quiet, economical, and accessible — perfect for medical visits, work trips, or a comfortable stay.

Popular amenities for Pine Island vacation rentals

  1. Airbnb
  2. United States
  3. Minnesota
  4. Goodhue County
  5. Pine Island