House vacation rentals in Mission Bay, San Diego

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Top-rated house rentals in Mission Bay, San Diego

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Guest favorite

Home in Mission Beach

4.99 out of 5 average rating, 136 reviews

Cozy California Beach Shack-Steps to Beach/Bay

This updated Mission Beach unit with great location close to beach and bay was designed to entertain and comfort the most discerning beach vacationer. This 2 bedroom / 2 bathroom unit offers all of todays modern amenities with 4K Smart TVs in every room, mini split heat/AC, Sonos Sound Bar in main room,washer/dryer, high end kitchen appliances and fastest fiber WIFI all while providing comfort and style with decorator furnishing throughout that will make you fall in love with vacationing again.

Guest favorite

Home in Mission Beach

4.96 out of 5 average rating, 209 reviews

South Mission Beach Ocean view luxury 3 bd 3 bth

Nicest place in South Mission Beach!!! Ocean view 3 bedroom 3 bath 2 car tandem garage new construction unit with air conditioning in the heart of South Mission Beach. Owner built for himself with no expense spared. 20 foot wall to ceiling glass panels that opens up completely to outside deck. 600sq ft penthouse deck with built in grill fridge outdoor dining table and sectional couch. All rooms have private dual shower bathrooms with Jacuzzi tub in master. May cost a little more but worth it.

Guest favorite

Home in Mission Beach

4.87 out of 5 average rating, 109 reviews

Ocean Front Home Sleeps 10+ Dream Beach Vacation

This large 1900 square foot three-bedroom non-smoking condo is an Ocean Front Penthouse. Has a private ground floor ocean front patio that can be used too. 10 people can sleep comfortably, all the bedrooms have cable TV's and fans. Your vacation home also features free wireless internet service. We have beach cruiser bikes, boogie boards, beach chairs, beach toys, beach umbrellas, surf boards, long boards, and razor scooters for your fun day at the beach! 2 private garage spaces for parking

Guest favorite

Home in Mission Beach

4.99 out of 5 average rating, 155 reviews

Steps To Beach! Family Friendly-Remote Office-Fire

House with Full-Size Car Garage, AC, private gas camping-style Fire in the Yard, 2 Patios, 2 Indoor Gas Fireplaces, Grill, & Laundry. 3 Bedrooms, 2 are primary with bathrooms, one with fireplace & kitchenette. Fully equipped Kitchen with outdoor Grill, just off the Dining area. Office Space plus fast 3 hub WiFi-6 coverage everywhere. 50 steps from the Beach or the Bay. Short ocean walk to PB with tons of restaurants & boutiques. Yelp lists 86 restaurants with 4-star+ reviews within easy walk.

Guest favorite

Home in Mission Beach

5.0 out of 5 average rating, 110 reviews

Beautiful Beach Home, Steps to the Ocean & Bay, AC

Beautiful beach home steps to ocean & bay. Up to 11 guests. King, queen & twin beds on the 3rd floor, queen bed on the 1st & 2nd floor, and queen sleeper in the family room. Bathroom on all levels. 2 car garage, washer/dryer, BBQ & patio, balconies, AC/heating, TV package. Restaurants, shops & grocery stores nearby. Minutes drive to Sea World, Zoo, downtown & Balboa Park. Note: We only accept Sat-Sat, 7 nights booking from 06/21/25-08/09/25. Sat-Sat booking for summer months every year.

Guest favorite

Home in Pacific Beach

5.0 out of 5 average rating, 193 reviews

Spacious 3 Bed w/ Rooftop Hot Tub & Scenic Views

This modern beach house is the perfect home for your San Diego getaway. You can't beat this location. You're minutes from Mission Bay and Garnet Ave, the heart of Pacific Beach which offers a variety of restaurants, nightlife and shops. This home has a spacious floorplan and sleeps 6 comfortably. You will feel right at home with the modern décor and high end appliances. Enjoy the scenic views in the hot tub on your private rooftop deck. This home is a little slice of San Diego heaven.

Guest favorite

Home in Ocean Beach

4.89 out of 5 average rating, 369 reviews

Ocean Beach Close to all

*We are Covid-19 aware! We have taken extra precautions--sanitizing all surfaces possible, including remote controls, door handles, light switches, etc... after each visit! And we open all the windows to aerate before the next guests! One bedroom granny flat, separate entrance with off street parking for midsize car or smaller. Three blocks to the beach. Located at the edge of downtown OB close to all restaurants and night life. Centrally located to all main San Diego attractions.

Guest favorite

Home in Mission Beach

4.98 out of 5 average rating, 167 reviews

Heaven's a Little Closer in a Cottage By the Sea!

60 Yards to the Beach!!!!!! Classic Mission Beach Cottage home, enjoy steps to the boardwalk & sand! Our ideal location allows for walking to several restaurants, cafes, bars, surf shops, markets, sports rentals, Crystal Pier, Santa Clara sports complex, Belmont Park & other amenities. Sea World, is just a stone's throw away! 2 night minimum stay. Nest doorbell camera system active on exterior property. No Pets, No Parties or gatherings of any size (see other details to note)

Guest favorite

Home in Pacific Beach

4.98 out of 5 average rating, 131 reviews

2300+ Sq Ft Brand New Home with Amazing Views!

Relax, Recharge, & Enjoy Panoramic Sunset Bay & Ocean Views In This Luxury Home! This beautiful brand new 4 bedroom private home featuring over 2300 sq ft boasts luxurious styling & finishes, designer tile and granite, wood flooring, pro-grade appliances, central air, indoor surround sound and outdoor music system all activated by simple voice command. Walking distance to everything from the boardwalk, bay, parks, ocean, restaurants, boat & jet ski rentals & tons night life.

Guest favorite

Home in Point Loma Peninsula

4.91 out of 5 average rating, 123 reviews

Point Loma Comfort w/ King Bed & Central Location

Our Point Loma studio offers extreme comfort and all the amenities you will need for a weekend getaway or extended vacation. You will sleep well on a king size Beautyrest Plush mattress with 800 thread count 100% cotton sheets. The kitchen is fully equipped and stocked with everything you need for a quick or gourmet meal. Enjoy DirectTV and access to your own WiFi network for work or entertainment. There is a private entrance and enclosed patio area.

Guest favorite

Home in Ocean Beach

4.97 out of 5 average rating, 395 reviews

Stunning Ocean View. Beach House. Garage/AC/Heat

Amazing ocean view and easy beach access -- while being in your own private spot with a birds-eye view of beach activity. My home (built in 2008 and well-maintained) is detached and gated-- away from crowds or shared spaces--giving you the opportunity to be safe and relaxed while taking in a stunning ocean view. My ideal guests are early-to-bed and early-to-rise to align with my neighbors in this less touristy beach area of San Diego.

Guest favorite

Home in Pacific Beach

4.92 out of 5 average rating, 132 reviews

Cozy PB Studio with Bikes, A/C and Self Check In

Charming & adorable studio, only 4 blocks from beach and bay! Within walking distance to best shops, restaurants, beach or bay. Fully furnished and equipped with everything you need for a short or extended stay in Pacific Beach! Close proximity to all San Diego attractions! 7 minutes to Sea World, 30 minutes to Lego Land, 15 minutes to the Zoo! Only 15 minutes from airport/downtown! Use our beach bikes to bike around PB for free!