
Guesthouse vacation rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Resort-living in private Studio @ Villa Paradiso
* Private, bright guesthouse immersed in a peaceful oasis of lush landscaping. The guesthouse is right in front of our swimming pool. * Fully remodeled: Kitchen, TV, Wifi, Nespresso & more. * Central location: 10 mins from Old Town Scottsdale, ASU, Sky Harbor Airport, Spring Training & more. Check out my profile for two Luxury B&B suite listings in the main house. Private bedroom & bath, full access to living areas + breakfast. Ask about photoshoots or events across the various property areas.

Entire Private Guest House with King Master
•Location, Location, Location! Extremely safe/social neighborhood just minutes from Oldtown! 5- minute drive by car and 10 minutes by E-scooters! •Bordered by lush greenery, your private backyard/covered patio is a perfect place to enjoy the outdoors •Recently built in 2022 with luxury, comfort, and entertainment in mind ~ you'll love the vibe of your private small backyard and small yet spacious 520sqft space. This guest house has its own private, yet beautiful entrance TPT 21476951 AZ 2026023

Luxury Modern Executive Retreat
Northeast Mesa location close to Tonto National Forest, the Salt River and Saguaro lake. 5 minutes from Boeing, Nammo Talley or MD Helicopter. 25 minutes from downtown Phoenix or Scottsdale. Nestled at the base of the Goldfield mountains. Contemporary open floor plan with modern design. Private entrance and single parking spot in front of the main house. Fast WiFi. Roku and cable TV. Beautiful, quiet neighborhood close to city amenities as well as biking and hiking trails. TPT# 21558238

Private Cozy Cottage in Gilbert. Close to it all!
Recently updated- the Cozy Cottage is perfect for your AZ stay and has everything needed to make your trip as comfortable as possible. Ideal for couples and young families. Safe for solo travelers. The neighborhood is upscale and a great location. Walk to the Gilbert Riparian a nature lovers paradise just 1/4 mile away. Shopping, restaurants, nightlife are 10 minutes away. 20 mins to Phx, Scottsdale or desert hiking. We are here to answer any questions or help with any issues 24/7.

Private, Convenient Studio Apartment
Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.

Saddle Lane Casita, North Central Phoenix, AZ
This hidden gem is centrally located on N Mountain in N Central Phoenix. 20 min to downtown Phx, 20 min to W. Valley, Scottsdale, Tempe, and Phoenix Int'l Airport. Our Casita features 1 room with a king bed, 1 bathroom, and a patio that faces west to enjoy Arizona's beautiful sunsets. We have a very steep driveway, and a full flight of stairs to the casita. If you have trouble walking or have knee and/or breathing problems, this is not the place for you.

Casita/ Heated Pool, Hot Tub, Amazing Amenities
Private Casita with an amazing steam room and upscale shower. Heated large pool and hot tub along with three covered outbuildings: full outdoor kitchen with BBQ, full stove, MW, Hot Water Sink and large bar area; living room and dining room with wood burning fireplace. A full set of dishes, pots and pans are in this area for your use. Lots of private sitting areas or just hang out in the orchard and pick citrus fruit from the 40 plus trees.

Cozy, Private Mid-Century Casita
Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite shows on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. Please, no children or animals.

Uptown Studio Great Neighborhood and Outdoor Space
Experience the charm of Uptown Phoenix in this peaceful garden studio, nestled in the historic district. This spacious retreat features a resort-style outdoor space, a cozy fire pit, and a sheltered dining area for relaxing evenings. Inside, unwind in a charming king-sized bed and a sparkling bathroom. Explore Uptown Phoenix, just minutes away, with vibrant restaurants, local shops, and exciting nightlife.

Mesa Casita with King Bed
Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.

The White Barn @ Freedom Farms
Kick off your boots and relax in this calm, stylish, private guest house on Freedom Farms! Explore the natural swimming pond on the property, venture out to the Sonoran desert for a nature hike, tube down the salt river or mountain bike in Usery! You'll find our location close to the city but not in the city.

La Cabra Casita: Poolside Oasis on an Urban Farm
Enjoy an experience unlike any other at our mini ranch in the heart of Chandler. After a day of sunshine in the beautiful Sonoran desert, retreat to your private La Cabra Casita. Relax by the pool, grill up some dinner, feed the goats and alpacas, and in the morning enjoy some fresh duck and chicken eggs.
Popular amenities for Mesa guesthouse rentals
Family-friendly guest house rentals

Best Little Guesthouse in Melrose !

Private Guest Studio in the Country

Private Casita Near Downtown Phoenix

Cottage

The Oasis Hideout

Townhouse Affordable Luxury Retreat & Pool

Private studio! Central to popular locations.

Coronado Private Casita (Private House)
Guest house rentals with a patio

Sunshine Studio! Phx/Scottsdale border!

Ruby's Hideaway, a historic red brick studio.

Private yard - Short walk to Mill - Historic House

Charming & spacious Casita! Like home only better!

Spacious Midtown guesthouse with full privacy

Zen Modern Casita w/ Private Pool + King Bed

Your favorite PHX guesthouse!

Lux DTPHX 1-Bed Casita w/Private Patio and Laundry
Guest house rentals with a washer and dryer

Adorable Willo Cottage in Historic Central Phoenix

Studio B industrial design

Al's Guesthouse at Peoria

Downtown Studio - Woodland Historic District

Enchanting Ahwatukee Secret Casita

Stunning Spanish Modern Guest House with Pool

Cozy Guest Home away from Home

Quiet 2BR Guesthouse on Acre -Gym/Newly built
When is the best time to visit Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | R1,748 ZAR | R1,973 ZAR | R2,060 ZAR | R1,662 ZAR | R1,523 ZAR | R1,437 ZAR | R1,437 ZAR | R1,333 ZAR | R1,420 ZAR | R1,627 ZAR | R1,679 ZAR | R1,645 ZAR |
| Avg. temp | 14°C | 16°C | 19°C | 23°C | 28°C | 33°C | 35°C | 35°C | 32°C | 25°C | 18°C | 13°C |
Quick stats about guesthouse rentals in Mesa

Total vacation rentals
Explore 150 vacation rentals in Mesa

Nightly prices starting at
Mesa vacation rentals start at R519 ZAR per night before taxes and fees

Verified guest reviews
Over 12,060 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
40 properties feature pools

Rentals with dedicated workspaces
70 properties have a dedicated workspace

Wi-Fi availability
150 of Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesa rentals

4.9 Average rating
Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Mesa's top spots, include Sloan Park, Golfland Sunsplash, and Hohokam Stadium
Destinations to explore
- Southern California Vacation rentals
- Las Vegas Vacation rentals
- Phoenix Vacation rentals
- Salt River Vacation rentals
- Palm Springs Vacation rentals
- Scottsdale Vacation rentals
- Henderson Vacation rentals
- Las Vegas Strip Vacation rentals
- Big Bear Lake Vacation rentals
- Joshua Tree Vacation rentals
- Sedona Vacation rentals
- Tucson Vacation rentals
- Rentals with a kayak Mesa
- Rentals with lake access Mesa
- Rentals with pools Mesa
- Rentals with a washer and dryer Mesa
- Rentals with an EV charger Mesa
- Rentals with an accessible height toilet Mesa
- Smoking-friendly rentals Mesa
- Cottage rentals Mesa
- Villa rentals Mesa
- Rentals with a fire pit Mesa
- Resort rentals Mesa
- Townhouse rentals Mesa
- Pet-friendly rentals Mesa
- Family-friendly rentals Mesa
- Hotel rentals Mesa
- Rentals with a sauna Mesa
- Tiny house rentals Mesa
- Fitness-friendly rentals Mesa
- Rentals with a home theater Mesa
- Rentals with a fireplace Mesa
- House rentals Mesa
- Serviced apartment rentals Mesa
- Rentals with outdoor seating Mesa
- Rentals with breakfast Mesa
- Waterfront rentals Mesa
- Rentals with a hot tub Mesa
- Rentals with a patio Mesa
- Condo rentals Mesa
- Private suite rentals Mesa
- Apartment rentals Mesa
- Guesthouse rentals Maricopa County
- Guesthouse rentals Arizona
- Guesthouse rentals United States
- Lake Pleasant Regional Park
- Chase Field
- Phoenix Convention Center
- Grand Canyon University Championship Golf Course
- TPC Scottsdale - Champions Course
- Salt River Fields at Talking Stick
- Arizona Grand Golf Course
- The Westin Kierland Golf Club
- Salt River Tubing
- Grayhawk Golf Club
- WestWorld of Scottsdale
- Tempe Beach Park
- Sloan Park
- Peoria Sports Complex
- Hurricane Harbor Phoenix
- Dobson Ranch Golf Course
- Lost Dutchman State Park
- Ocotillo Golf Club
- We-Ko-Pa Golf Club
- Red Mountain Ranch Country Club
- Seville Golf & Country Club
- Trilogy Golf Club at Power Ranch
- Oasis Water Park
- Gainey Ranch Golf Club
- Things to do Mesa
- Things to do Maricopa County
- Sports activities Maricopa County
- Art and culture Maricopa County
- Nature and outdoors Maricopa County
- Food and drink Maricopa County
- Wellness Maricopa County
- Things to do Arizona
- Entertainment Arizona
- Sports activities Arizona
- Art and culture Arizona
- Sightseeing Arizona
- Food and drink Arizona
- Tours Arizona
- Wellness Arizona
- Nature and outdoors Arizona
- Things to do United States
- Sports activities United States
- Tours United States
- Food and drink United States
- Entertainment United States
- Wellness United States
- Nature and outdoors United States
- Art and culture United States
- Sightseeing United States

