
House vacation rentals in Matlacha
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Top-rated house rentals in Matlacha
Guests agree: these houses are highly rated for location, cleanliness, and more.

McGregor’s Gem• Heated Pool 3BR/2BA River District
🌴 Welcome to McGregor’s Gem—your ideal Southwest Florida retreat! Dive into relaxation in your private heated pool, spread out across three bedrooms and two baths, and enjoy the perfect blend of peaceful tree-lined neighborhood living just minutes from the charming Downtown Fort Myers River District, world-class beaches, and top local attractions.☀️ Whether you’re traveling with family, friends, or on business, this home offers all the modern comforts you need for a relaxing, stress-free stay

Bring Boat- speakeasy- 3/3 w/dock-Walk2town
It’s all about the WOW! You won’t want to leave this chic unique 3/3 full bath house water. Hidden fun secret SPEAKEASY. Keep it to yourself & then share w/ the rest of the family when the time is right. Tie your boat to your own dock & walk to restaurants& shops. Fully equipped kitchen, washer & dryer WiFi, TVs, games. 1 SMALL dog allowed for additional fee. 2 bikes, board games, donkey kong arcade & Bbq. Small events allowed. For larger family’s and lg dogs a 2nd home is available next door.

LUX Villa w/ Private Salt Water Pool, Lanai, Canal
Are you looking to swim, relax outdoors, fish and take in beautiful sunsets on a wide gulf access canal? If so you will fall in love with this stunning newly constructed custom built home! The 2750 square foot home is bright & airy with two main bedroom on-suites & a separate family wing! The gourmet kitchen, dining room & great room open via large sliders to the lanai & pool w/ views of the canal in much desired SW Cape! Beach inspired villa! Large captains walk & Tiki! Check out our reviews!

Peaceful Retreat: Heated Pool Villa in Cape Coral
Unwind in the tranquil embrace of The Good Life Villa, your idyllic retreat nestled in the heart of Cape Coral's tropical paradise. Indulge in the soothing warmth of the private heated pool, soak up the sun's golden rays on the expansive lanai, and create lasting memories within the fully equipped, kid-friendly home. Explore Cape Coral's vibrant tapestry of white sandy beaches, fresh seafoods and exhilarating boating adventures. Embrace the true meaning of the good life at The Good Life Villa.

Spacious 3/2 50’ Dock-HotTub-Walk 2 restaurants
So much love is put into this home you will see and feel it. Can sleep up to 10. 50’ of dock to Tie up multiple boats. This close to town home is in a quiet neighborhood with Gulf access. You can drink your coffee and mimosas overlooking the tranquil water. Don’t want to cook breakfast? You can walk to town in 10 min or ride one of the bikes to the Perfect Cup or have lunch at another Matlacha restaurant. Your family will enjoy fishing off the dock, corn hole, board games, bbq, and Pac-Man.

Sunset POOL Waterfront Kayak bikes fish from dock
New POOL Gulf access waterfront oasis. Downstairs unit 1 bedroom, 1 full bath with bathtub, washer/dryer, kitchen, BBQ grill. Sleeps 6 comfortably. 1 bedroom with pillow top queen bed, memory foam pull out sofa, futon style bed & pack /play crib. In the heart of Matlacha tucked away yet walking distance to town. Bring your boat, use the boat dock, kayak, canoe, bicycles and fishing rods. Jump in the pool after a hot days! Only 9 walking blocks away to restaurants, shops and boat ramp.

Matlacha Paradise! NEW Waterfront Home-Free Kayak
Matlacha is for LOVERS! Lovers of relaxation, fishing, art, friends, social scenes and enjoying Life in a beautiful location ON THE WATER! Matlacha had damage from Ian. Our new home - none. You can still walk to great restaurants, shops and the fishing bridge. Enjoy the water in Matlacha & the Barrier Islands. Use our 1 person kayak for fun or fishing from our 8'X22' FUN & SUN deck docked in the back canal with picnic table & loungers. Relax, sun, grill and fish.

Matlacha Deep Water Island Oasis
Welcome to historic Matlacha. This home on a deep-water canal is a Fishermans paradise. The bedroom has a queen size bed and living room has pull out couch. There is a full kitchen with all necessities. Come grill on the waterfront screened in porch, or fish right from the deck. Bring your water toys right to the house or enjoy the beautiful sunsets. Walking distance to all Matlacha has to offer.

Family Waterfront Home, Pool & Spa
Escape to Cape Coral! This 4BR, 2BA canal-front home sleeps 8 and offers a heated saltwater pool & spa, spacious outdoor living, and a private dock perfect for fishing or soaking in the Florida sunshine. Inside, enjoy open living areas, a full kitchen, and comfortable bedrooms. Ideal for families and friends looking for relaxation, fun, and unforgettable memories in a sunny waterfront retreat.

The Funky Flamingo
Funky and eclectic home in historic Matlacha, just steps from art galleries, waterfront restaurants, and local shops. Explore Pine Island’s backwaters with our canoe and kayaks—world-famous for redfish, snook, trout, sheepshead, and tarpon. After a day fishing or paddling, unwind on the breezeway while enjoying the peaceful sounds of nature and nesting ospreys.

Golden Eye - amazing sunset view. Kayaks included
** NO CONTACT CHECK-IN** Matlacha, it’s a water sports paradise! World class fishing, boating, kayaking, beautiful sunrises and sunsets! See nature come to life and enjoy the tranquility and peacefulness this area offers. Grab your loved ones and get ready to be recharged! Plan a Spring/Summer Vacation getaway! WEEKLY and MONTHLY specials are available

Modern Oasis pool paradise
Location! Location! The entire place. This is a brand new Condo with gorgeous pool located next to supermarkets, restaurants including famous seafood restaurant, very close to Captiva, Fort Myers and Sanibel beaches Beautiful modern decor quiet secluded amazing!!! Great pool. No pets no service dogs no comfort pets allowed owner is allergic.
Popular amenities for Matlacha house rentals
House rentals with a pool

Coastal Cowgirl - Heated Pool

Island Paradise Awaits You

Florida, Cape Coral, SunShine

Bliss on the Bay-Brandnew Vacation Home Cape Coral

2 Kings, Pool, Gulf Canal, Game Room and Kayaks

Private Home w/ Heated SPA&Pool and Screened Lanai

Boater’s Paradise in Bokeelia!

Villa Sunset Serenade II
Weekly house rentals

The Little Yellow Retreat with boat parking

Peaceful Lakeview Retreat / Screened Porch & Bikes

Best Beach Cottage #2

Tranquility, pool, ocean access, boat lift

Sunset Canal - Waterfront Heated Salt Pool Golf

Cape Escape | Hot Tub | Heated Pool | Game Room

Cape Coral Family Villa with Heated Pool & Spa

Waterfront Oasis with Boat Lift & Hot Tub
Private house rentals

Gorgeous Sanibel Surfside Oceanfront Residence

Sueños Villa

Brandnew Villa - pool & spa at canal south facing

Sea you at the Cape

WF Oasis~Htd Pool~Spa~Pets4Free~BBQ~Big Lanai~Dock

Waterfront Oasis |Heated Pool |Fishing Dock| Lanai

Waterfront • MiniGolf • Game Room • Heated Pool !

3 Bed 2 Bath Luxury Pool Home Salt Water Canal!
Quick stats about house rentals in Matlacha

Total vacation rentals
Explore 40 vacation rentals in Matlacha

Nightly prices starting at
Matlacha vacation rentals start at R686 ZAR per night before taxes and fees

Verified guest reviews
Over 1,180 verified reviews to help you choose

Family-friendly vacation rentals
30 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
40 of Matlacha vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Matlacha rentals

4.9 Average rating
Matlacha stays are highly rated by guests—averaging 4.9 out of 5!
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