Vacation rentals in Lee County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Lee County

Guests agree: these stays are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
Superhost
The spacious living area features a combination of plush leather seating and a cozy plaid sofa. Light streams through the window treatments, illuminating the well-equipped kitchen with wood cabinetry. Hardwood flooring adds warmth, enhancing the inviting atmosphere of the shared space.
Camper/RV in Fort Myers
4.8 out of 5 average rating, 112 reviews

Very private, clean, spacious in perfect location.

Extra large 40 feet long high ceiling RV with 4 slide outs. Great location 9 miles from Fort Myers Beach & 7 miles South of Downtown. 5 grocery stores within 1 mile Walk to Suncoast Arena, Barbara B Mann theater, restaurants & FSW College Private entrance 6ft fenced Patio Beach essentials King bed Walk in shower Sofa bed in living room Large fridge 2 Smart 4K TV Full kitchen, coffee maker. Washer & dryer Dual AC, weber grill 2 Parking spots 50 amp EV outlet & charger. 12 miles to SWFL Airport

Top guest favorite
The private pool is surrounded by a screened enclosure, featuring a clear blue surface reflecting sunlight. Steps lead into the pool, and lounging chairs are placed nearby. The landscaped yard is visible beyond the pool area, providing a serene atmosphere for relaxation.
Home in Cape Coral
5 out of 5 average rating, 44 reviews

5 Star Experience, Heated Pool close to Everything

Your perfect Oasis Getaway near the serene Caloosahatchee River in beautiful Cape Coral awaits your stay. Conveniently situated, our home offers easy access to local attractions. Nestled in a secure and safe community, you can relax and unwind with peace of mind. Whether you're looking to unwind by the pool, explore the beauty of Cape Coral, or enjoy fun-filled activities with loved ones, this home has it all. Book your stay today and create unforgettable memories in this charming Florida haven!

Top guest favorite
The outdoor area showcases a large pool surrounded by stone patio flooring. Comfortable lounge chairs are positioned beside the pool. Lush greenery and palm trees frame the space, contributing to a private and tranquil setting.
Home in Fort Myers
4.94 out of 5 average rating, 154 reviews

Paradise on Estero Bay

Welcome to Mullock Creek a Boater's dream! Southwest views boasting breathtaking sunsets overlooking gulf access canal from your spacious backyard, just minutes away from shopping and dining at Coconut Point, and Gulf Coast Town Center. This stunning Key West Style home has been beautifully maintained and updated offering a lovely front entrance, fully equipped kitchen, spacious Living Room, dining room, Wi-Fi, private driveway with access to the open garage, fully furnished and private pool.

Top guest favorite
A bright and spacious living area features a cozy seating arrangement with neutral-colored sofas and decorative pillows. A dining table with white chairs sits nearby, complementing a woven pendant light above. Large windows provide natural light and views of the surrounding landscape.
Condo in Sanibel
5 out of 5 average rating, 18 reviews

Sunny Sanibel - Gorgeous Loggerhead Walkout Unit

Loggerhead Cay 351 is a fantastic ground floor walk out condo residence in the sought after Loggerhead Cay development of Sanibel`s East End. "Sunny Sanibel" features two spacious bedrooms and bathrooms, a fully equipped kitchen, direct Gulf views, and a walk out patio, this residence is both beautiful and functional! With resort grade amenities including tennis, pickleball, Olympic sized heated swimming pool, shuffleboard, and community grills, guests will surely return year after year!

Guest favorite
The image shows a private pool area with a heated saltwater pool, surrounded by a screened enclosure. The serene lake view is visible in the background, complemented by palm trees. Comfortable loungers frame the pool, creating an inviting outdoor space.
Home in Cape Coral
4.89 out of 5 average rating, 44 reviews

Vacation in Cape Coral in direct sea situation.

Villa Pleasure - enjoy cosy days in the beautiful villa, with a fantastic view directly on the Honeymoon Lake. The south facing Villa Pleasure offers comfortable accommodation for a maximum of 8 guests in 4 bedrooms in northwest Cape Coral. The Villa is brightly decorated and decorated with attention to detail. Outside there is a heated pool (with salt water technology) with plenty of privacy and a barbecue grill and sun loungers that invite you to sunbathe. Children up to 6 years free.

Top guest favorite
A large heated pool is showcased within a spacious screened lanai. Comfortable lounge chairs are positioned beside the water, and a serene backyard is visible beyond the pool area, featuring lush greenery and flowering plants.
Home in Bonita Springs
4.96 out of 5 average rating, 149 reviews

Renovated Pool Home in Historic Bonita Springs

Welcome to our just renovated single family pool home in the heart of historic Bonita Springs. Less than 5 miles to the beaches. You can walk to coffee shops, parks, restaurants and all sorts of markets, etc. The living area extends outside in the huge screened lanai where we have a new outdoor sectional sofa. The pool is large and heated. A very upgraded kitchen with new soft close cabinets, quartzite counter tops & brand new appliances. It's a comfortable open concept design.

Top guest favorite
A two-story canal front home is surrounded by lush greenery and palm trees. A boat dock is visible with a boat ready for use. The clear water reflects the sky and nearby structures, conveying easy access to the canal and Gulf.
Home in Bokeelia
5 out of 5 average rating, 15 reviews

2/2 Home in Bokeelia, Boat Lift Included!

This two level 2 bedroom, 2 bathroom canal front home is exactly what's needed for an excellent vacation on beautiful Pine Island! This property has beautiful tropical décor to get you settled into the island lifestyle. You can relax and enjoy the views and wildlife on the back patio or grill the day's catch. This canal has incredible Gulf access and you will be out to the intra-coastal in minutes for some of the best fishing in not just the country, but the world. Bring your boat!

Top guest favorite
The kitchen is designed with modern finishes, featuring an island with seating and a dining table with white chairs. Natural light filters through the window blinds, illuminating the room. Stainless steel appliances and cabinetry are visible, enhancing the functional layout.
Home in Fort Myers
5 out of 5 average rating, 28 reviews

2BR Retreat by Sanibel & Fort Myers Beaches

Experience comfort and convenience in this spacious 2BR home, just minutes from Sanibel Island and local beaches. Ideal for any traveler, the home offers a king bedroom, queen bedroom, and a pull-out couch. Enjoy modern amenities like fast Wi-Fi, smart TVs, washer and dryer, and a private entrance. Relax with outdoor seating, ample parking, and easy access to local dining, attractions, and the marina. Your perfect coastal getaway awaits!

Top guest favorite
A serene pool area overlooks the Caloosahatchee River, with the sun rising on the horizon. Lush palm trees provide shade while the calm water reflects the light. The pool's clear water invites relaxation, and a dock is visible in the background, enhancing the tranquil ambiance.
Home in Cape Coral
4.98 out of 5 average rating, 64 reviews

Beautiful River Front House with Pool and Hot Tub

Enjoy life on the water with this stunning river front house overlooking the Caloosahatchee River! This luxurious home features an outdoor oasis with Adirondack chairs, an outdoor kitchen and pool/hot tub area perfect for entertaining. Lush palm trees provide shade as you relax in seclusion. Inside, open floor plans connect you to the tranquil river views. Make every day a peaceful getaway in this one-of-a-kind waterfront paradise.

Guest favorite
A comfortable living area features a beige sofa with decorative cushions and a ceiling fan above. A round dining table made of wood is accompanied by stylish chairs. Natural light filters through two partially covered windows, creating a warm space highlighted by a woven pendant light.
Home in Fort Myers
4.94 out of 5 average rating, 66 reviews

Best Beach Cottage

If you want to stay in Fort Myers, this designer-furnished beach cottage-style home is where you want to stay. Centrally located off of the beautiful McGregor Blvd, which is perfect for biking, between downtown Fort Myers and Fort Myers Beach. It is also a short drive from Sanibel Island and other desirable beaches. 25 minutes away from The airport this house includes all appliances including a washer, dryer, and outdoor grill.

Guest favorite
A screened lanai surrounds the inviting heatable pool, which features steps leading into the water. A folded turquoise towel lies on a black wicker chair, accompanied by a pair of sunglasses. In the background, serene lake views and a cloudy sky can be seen.
Home in Cape Coral
4.93 out of 5 average rating, 73 reviews

Lakefront Villa with large dock, heated pool

Ruby’s Lake Retreat - our beach-themed vacation home located right on Thunderbird Lake in the sought after 8 Lakes neighborhood invites you to spend a dream vacation in Southwest Florida. Enjoy unique lake views from nearly every room and the outdoor area, the open floor plan of the house, the large bedrooms and living area and the screened in, spacious lanai with a heatable pool.

Top guest favorite
A light-filled living area showcases large windows with flowing curtains. A comfortable couch is adorned with yellow pillows, and a lamp provides additional lighting. A bar counter with stools separates the living space from the kitchen, enhancing the open concept design.
Home in Fort Myers
4.88 out of 5 average rating, 245 reviews

The Beachy Retreat

This is the ultimate getaway for our guests. Our cozy newly renovated retreat is in the perfect location that is close to the beach, near all the best restaurants, and has all the amenities you will need for a breezy family vacation. Just a short 10 min drive to all the best beaches (Sanibel Island and Ft. Myers Beach), shopping locations, and more!

Popular amenities for Lee County vacation rentals

Destinations to explore

  1. Airbnb
  2. United States
  3. Florida
  4. Lee County