We’re sorry, some parts of the Airbnb website don’t work properly without JavaScript enabled.

Airbnb your place

Lake house vacation rentals in Lake Moultrie

Find and book unique lake houses on Airbnb

Top-rated lake house rentals in Lake Moultrie

Guests agree: these lake houses are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Top guest favorite

A spacious living area is highlighted by exposed wooden beams and large windows, allowing natural light to fill the room. A light-colored sectional sofa and a tan couch provide comfortable seating. A wooden coffee table is centered on a textured rug, with modern art displayed on the wall.

Home in North Charleston

4.97 out of 5 average rating, 153 reviews

Serene Nordic Retreat with Charleston Vibes*

Welcome to our beautifully renovated home located right above downtown Charleston in desirable neighborhood of Park Circle. A fully equipped kitchen with all amnesties to cook for friends and family. A kitchen island with 6 seats and a spacious living room with 75” TV is waiting for you. The beds are of the highest quality and the bathrooms are designed luxuriously. A Scandinavian inspired home with games to bond! Enjoy a lively dining and nightlife scene! Walk to the US-largest kids playground

A stylish living area features a modern black sofa accented with patterned cushions. A unique silver sculpture sits on the glass coffee table, reflecting light. Behind the sofa, a set of abstract wall art panels adds visual interest. Natural light filters through the windows.

Home in North Charleston

4.92 out of 5 average rating, 113 reviews

NEAR HISTORIC DOWNTOWN | LAKE ACCESS + BALCONY

This beautiful two-story townhouse is perfect for families or remote workers wanting the comforts of home for a relaxing stay in Charleston. The modern design, hardwood floors, private balcony, and lakeside location make this the perfect location from which to explore historic downtown. Beautiful beaches and the airport are just a short drive away. 5 Min Drive to Tanger Outlet 7 Min Drive to Park Circle 12 Min Drive to Riverfront Park 12 Minute Drive to downtown Experience North Chas With Us!

Top guest favorite

A wooden deck extends over calm waters, surrounded by lush greenery. Sunlight filters through the leaves, creating a serene atmosphere. The lake reflects the blue sky and distant trees, inviting peaceful moments and wildlife observation.

Home in Mount Pleasant

4.96 out of 5 average rating, 100 reviews

Family fun on the lake: MP Gateway. #ST250217

Rental Permit # ST250217 Experience the unparalleled location of this MP home! Situated in an intimate dev with lake views, 4 minutes from Towne Centre (shopping, dining, entertainment). Beach lovers will appreciate the quick 13-minute drive to Sullivan's Island and Isle of Palms . Explore the charm of the Old Village and Pitt Street (7 minutes) or the waterfront buzz of Shem Creek (10 minutes). Downtown Charleston is also easily accessible within 20 minutes, and quick access to Highway 526 .

Home in Eutawville

4.96 out of 5 average rating, 68 reviews

Heated Indoor Pool on Lake Marion with Dock

Lake Marion Lakefront on a private 2.5 wooded lot. Two houses - 4000 sq. ft. of space, plenty of room for 14! Dock to fish off of or bring your fishing boat. Heated indoor pool and Margaritaville-themed bar. Firepit, pool table, games, and dining table for 14 people. Great spot for Family Gatherings or Friends' Getaway. Golf, fishing, fruit picking, and amazing country food restaurants - 25 min drive. 5% Discount Gov. Employees :) Parties over 14 ppl ++ fees apply, details discussed prior.

Top guest favorite

5 out of 5 average rating, 13 reviews

Lakefront Fishing + Grilling | Home Sweet Home!

Escape to our serene Lakehouse Hideaway on Lake Moultrie, the perfect retreat for family vacations, fishing trips, or peaceful getaways. This charming 3-bedroom, 2-bath home features a spacious family room, fully equipped kitchen, kids’ room, queen bedrooms, and a lakefront porch on nearly an acre of private property. Enjoy fishing, relaxing, and exploring Lowcountry dining nearby. Just over an hour from Charleston, this tranquil oasis offers the ideal blend of relaxation and adventure.

The home is a two-story structure with a light exterior and dark shutters. A welcoming blue door is centered at the front. Surrounded by trees, the spacious yard is dotted with palm trees, and a pathway leads to the entrance.

Home in North Charleston

4.91 out of 5 average rating, 195 reviews

Hot Tub Haven! 7 Beds Endless Summer

Welcome to The Endless Summer! Spacious 5-Bedroom Home - Sleeping ideal for groups! -Escape to tranquility in this laid-back and quiet neighborhood just one exit from the airport. The Endless Summer is ideal for both small and large groups of friends or families, offering a perfect blend of comfort and convenience. 12 min to downtown Charleston 8 min to Tanger Outlet Mall and Top Golf 6 min to Coliseum/Performing Arts 29 min to Folly Beach 8 min to the airport Permit Number: 20240150

A spacious deck features four comfortable chairs arranged around a decorative rug, offering a relaxing spot to enjoy views of the lake and surrounding area. Overhead lights enhance the inviting atmosphere, while clear blue skies provide a picturesque backdrop.

Home in North Charleston

4.79 out of 5 average rating, 117 reviews

3 BR - 10 Minutes to Downtown w/ Lakefront Deck

Welcome to our spacious and charming townhouses on Lake Palmetto! We own and operate multiple townhouses in the area, depending on your group size and budget we’ll accommodate accordingly. Please inquire and we will make it happen! These AirBnBs are conveniently located next to Park Circle, Tanger Outlets, and the Charleston International Airport. Each home has large living areas and are perfect for large families or groups of friends! City of North Charleston STR Permit #: 2025-0070

A spacious living area showcases warm wooden walls and high ceilings with exposed beams. Natural light fills the room through large windows, revealing views of the outdoors. A stone fireplace is featured along one wall, while comfortable seating arrangements offer a cozy atmosphere.

Home in Summerton

4.97 out of 5 average rating, 157 reviews

Luxurious Lakefront Log Home W/Pool & hot tub

Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

A scenic view of the lake is presented, featuring a long dock extending into the calm water. Lush greenery and palm trees frame the foreground, while a faint rainbow appears in the backdrop under a partly cloudy sky.

4.97 out of 5 average rating, 157 reviews

Santee lakefront home, big water right off I-95

Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

Top guest favorite

A spacious covered porch offers a view of the lake through large screens. A grassy area extends toward the water, where a private dock can be seen. Pine trees frame the scene, providing a natural backdrop to the tranquil setting.

Home in Moncks Corner

4.81 out of 5 average rating, 146 reviews

Lake Moultrie, Lake front with private dock

Lake front living. Sandy beach and private dock. Children and pets welcome. Enjoy swimming and fishing at your private resort. Local attractions are Old Santee Canal Park, with boardwalk along the Tail Race Canal. Pinopolis Lock, take your boat through the locks and travel to Charleston via intercoastal waterway. Mepkin Abbey, a working monastery and Cypress Gardens with hiking trails and butterfly house are in the area. Or you can simply stay at the cabin to unwind and relax.

Top guest favorite

An aerial view captures the lakeside property surrounded by lush greenery and mature trees. The mobile home sits adjacent to the water, featuring a landscaped yard and access to a private boat launch. Nearby structures and pathways are also visible.

5 out of 5 average rating, 13 reviews

Fish Haven

Looking for a quiet, yet charming lakeside property? Look no further! Come enjoy this three-bedroom home with direct access to the diversion canal and a private boat launch. Great space for fisherman, families or couples. Ample space for your boat and hitch. Enjoy your days fishing, savor your afternoon by having a beverage and grilling out on the back patio. Spend the evenings playing cornhole and relaxing by the fire pit. It is the perfect setting to create wonderful memories!

The exterior of the home is showcased, highlighting a charming façade with a mix of brick and siding. Large windows reflect natural light, and the welcoming porch features seating. A landscaped yard and tall trees provide a serene backdrop, complementing the overall inviting atmosphere.

Home in Summerton

4.83 out of 5 average rating, 110 reviews

Perfect family vacation retreat at Lake Marion, SC

Great family escape! Enjoy our beach, dock and boat ramp as well as our game room and fully stocked kitchen. This is the complete family reunion location! We purchased our lake home, built in 1980, in 2009 and began renovation. We updated the kitchen and baths, plus new carpet, tile, windows, appliances, and a complete update to the exterior with new landscaping. We also replaced the dock and the seawall. It has been a journey and we hope you love our house as much as we do!

Vacation rentals for every style

Get the amount of space that is right for you

Houses

A space thats all yours, with room for everyone

Hotels

Stylish accommodations and amenities

Unique stays

Spaces that are more than just a place to sleep

Popular amenities for Lake Moultrie lake house rentals

Free parking on premises

Air conditioning

Waterfront lakehouse rentals

Top guest favorite

The photo captures a serene lakeside scene, featuring tall trees with greenery and moss. A wooden dock extends over the tranquil water, while a gently sloping grassy area leads to the shore, providing ample space for relaxation and outdoor activities.

Home in Elloree

4.94 out of 5 average rating, 81 reviews

Old Man’s Fishing Hole (Lake Front-Lake Marion)

A sunlit sunroom features large windows overlooking the lake, providing a serene view of the greenery beyond. Comfortable seating with soft cushions is arranged, inviting relaxation. A ceiling fan adds a touch of comfort, enhancing the peaceful atmosphere of the room.

Home in Moncks Corner

4.92 out of 5 average rating, 25 reviews

Lovin’ Lake Life

A wooden dock extends into the calm water, leading to a viewing platform at the end. Green grass borders the shore, and the sky is filled with fluffy white clouds, creating a serene backdrop for the tranquil lake scene.

Home in Manning

4.88 out of 5 average rating, 8 reviews

Cozy 3 bed 2 bath waterfront lake house

The image captures a serene sunset over Lake Marion, with vibrant colors reflected in the water. Tall trees frame the view, and a wooden deck with railing leads towards the dock, inviting peaceful outdoor moments.

Home in Cameron

4.89 out of 5 average rating, 28 reviews

The Cypress House

A bright living room features a plush blue sectional sofa and a sliding glass door that opens to a spacious patio. Natural light enters through large windows adorned with sheer curtains. Two elegant bird paintings enhance the decor of the neutral-toned walls.

Home in North Charleston

4.92 out of 5 average rating, 50 reviews

'Blue Heron' Luxury on the Lake

A single-story house is viewed from the yard, featuring a covered porch and a ramp leading to the entrance. A boat is positioned in the yard, with a spacious lawn and a few trees visible in the background, along with a car parked nearby.

Home in Summerton

4.95 out of 5 average rating, 44 reviews

Cozy 3 bed 2 bath on the waterfront

The exterior of a welcoming home is presented, featuring a gabled roof and a large front porch. Lush greenery, including shrubs and trees, surrounds the property. A smooth pathway leads to the entrance, and vibrant flowers add color to the landscape.

Home in Eutawville

4.89 out of 5 average rating, 18 reviews

Lakeview Leisure-Face to the Sun

A serene view of Lake Marion is depicted, showcasing calm waters reflecting vibrant sunset colors. A private dock extends into the lake, surrounded by tall trees and greenery. The landscape reveals gentle slopes leading down to the water's edge, creating a peaceful lakeside atmosphere.

Home in Manning

4.92 out of 5 average rating, 12 reviews

Lake Marion Beauty w/ 5br/3ba

Pet-friendly lake house rentals

Top guest favorite

Home in Ridgeville

4.91 out of 5 average rating, 34 reviews

Red Dogs River House-Edisto River- *Boat Landing*

Top guest favorite

A wooden deck extends over the Edisto River, equipped with a metal railing and a dock featuring a ladder for easy access to the water. A single pink chair is positioned on the deck, surrounded by lush trees that frame the peaceful river view.

Home in Ridgeville

5 out of 5 average rating, 42 reviews

Riverhouse Retreat on the Edisto River

A tranquil view of Lake Marion is captured, featuring calm waters reflecting the sky and surrounding greenery. In the foreground, a wooden dock post is visible, with the shoreline and tree line defining the horizon. Fluffy clouds dot a bright blue sky.

Home in Summerton

4.88 out of 5 average rating, 48 reviews

Santee/Lizzie's Creek Lakefront

Home in Summerton

4.84 out of 5 average rating, 57 reviews

Lakefront home with boat ramp and game room

The front exterior of the house is presented, featuring light-colored siding and a welcoming blue front door. A small porch is visible with white railings, and large windows allow natural light into the interior. The surrounding yard is grassy with scattered trees and landscaping.

Home in Eutawville

5 out of 5 average rating, 14 reviews

Fisherman’s stay! Lake Getaway!

Top guest favorite

A serene view of Lake Marion is presented, featuring a well-maintained grassy area with four curved adirondack chairs arranged around a fire pit. A private dock extends into the water, providing boat access, under a clear blue sky dotted with soft clouds.

Home in Summerton

5 out of 5 average rating, 24 reviews

The Heron Lake House

Top guest favorite

A wooden dock extends over the calm water, featuring weathered boards and a stable appearance. Nearby, grassy areas lead to a fenced yard, while a house and trailer are visible in the background, nestled amongst trees for a natural setting.

Home in Summerton

5 out of 5 average rating, 38 reviews

A Lake Slice of Heaven

Top guest favorite

A private sandy beach area is highlighted, featuring a wooden dock with a blue umbrella providing shade. Two black chairs are positioned on the sand, overlooking a calm lake with clear blue waters and a bright sky.

Home in Summerton

5 out of 5 average rating, 23 reviews

Almost Heaven on Lake Marion, SC

Private lake house rentals

A spacious living area features a large area rug with intricate patterns, centered by a dark coffee table. Comfortable sofas and a chair with soft cushions are arranged to create a cozy seating area. Natural light fills the room through multiple windows.

Home in Manning

4.81 out of 5 average rating, 57 reviews

Jewel on the Lake

Home in Manning

5 out of 5 average rating, 7 reviews

Eagle Point Poolside Escape

A spacious outdoor area features a large grassy lawn, a swimming pool, and an enclosed porch. A shaded pavilion with seating stands nearby. The home showcases a blend of modern design and natural surroundings, creating an inviting setting for relaxation and outdoor activities.

Home in Summerton

5 out of 5 average rating, 7 reviews

Lake House Retreat

A spacious, grassy yard is bordered by a wooden fence, leading to a serene waterfront with calm waters. Towering trees provide shade, while a clear blue sky features fluffy white clouds. A private boat ramp is visible, along with the distant structure of a shed.

Home in Bonneau

4.63 out of 5 average rating, 160 reviews

Lake House on the Water with Boat Ramp!

A softly lit outdoor deck features a door leading into a cozy indoor space. String lights provide gentle illumination, while potted plants and outdoor furniture create a welcoming environment. The interior space is faintly visible through the glass doors, suggesting a comfortable living area.

Home in North Charleston

4.67 out of 5 average rating, 9 reviews

Lakefront Home near Everything!

Two adirondack chairs, one blue and one green, are positioned on a wooden dock facing a tranquil lake. The setting sun casts warm orange and red hues across the sky, reflecting softly on the water's surface, highlighting the peaceful lakeside atmosphere.

Home in Summerton

5 out of 5 average rating, 6 reviews

Lake Marion Cottage

Home in North Charleston

4.93 out of 5 average rating, 43 reviews

Modern Lakehome/Close to Downtown/Across Coliseum

An outdoor deck space is showcased with multiple seating options, including a wicker chair and a rocking chair. The area is surrounded by trees, offering views of the lake through large openings. A wooden picnic table is visible in the background.

Home in Bonneau

4.93 out of 5 average rating, 68 reviews

Lakefront Retreat w/ Game Room & Private Dock!

Destinations to explore