Lake house vacation rentals in South Carolina

Find and book unique lake houses on Airbnb

Top-rated lake house rentals in South Carolina

Guests agree: these lake houses are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Anderson

4.93 out of 5 average rating, 149 reviews

Broadway Lake Retreat in Anderson, SC

Located on Broadway Lake in Anderson, SC. 300-acre lake great for pontoons, fishing, and having a great time. Features a flat lot with 250 feet of water frontage. Private dock & 2 kayaks for your use. House features panoramic views of the lake. Short boat ride to Pine Lakes Golf Club where you can enjoy a round of golf or dine at J.R. Cash's on Broadway Restaurant & Bar. McFall's Landing event venue is less than a quarter-mile drive from where you can launch your boat or schedule an event.

Jan 20 – 27

R2,631 ZAR per night

Guest favorite

Home in Inman

4.93 out of 5 average rating, 230 reviews

LakingitEz..3BR/2BA amazing sunsets & hot tub

LAKEFRONT, awesome sunsets, amazing neighborhood with loads of charm! 3BR/2BA house on secluded acre plus wooded lot. Relax on large screened in porch with amazing lake views or in the hot tub built in deck. 2 bedrooms on main (king & queen) with hall bath & laundry. The upper loft bedroom has 2 full beds & bathroom overlooking the lake. Pet friendly w/fee fenced in backyard with doggie ramp! Awesome location just minutes to both I-26 and I-85. Easy access to Spartanburg, Greenville, & Greer!

Nov 6 – 13

R5,323 ZAR per night

Guest favorite

Home in Iva

4.98 out of 5 average rating, 156 reviews

Moonshine Bay

Your home away from home on South Carolina’s hidden gem, Lake Secession. Private wooded drive opens up to phenomenal lake view with shallow water entrance. Great for water sports, swimming, fishing and relaxation. If swimming isn’t for you, many beautiful reasonably priced golf courses are near by. Only 10 miles from Anderson & 36 miles to Clemson Stadium. Pull your boat to the dock or just enjoy some of our non-motorized lake toys. You’ll love it so much you want to come back year after year!

Mar 11 – 18

R3,005 ZAR per night

Guest favorite

Home in Westminster

4.94 out of 5 average rating, 256 reviews

Waterfall Views, Lake Hartwell, Highland Architect

Come and enjoy nature with 100+ acres to roam. Paths for long walks. Architect James Fox designed this cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Jan 23 – 30

R8,633 ZAR per night

Guest favorite

Home in Aiken

4.95 out of 5 average rating, 228 reviews

Beside Still Waters Country Cottage

Isolated! Peaceful! Amazing Lakefront Property! Gorgeous, fully equipped and thoroughly sanitized 3B/2B getaway on beautiful lake! Dock for fishing & swimming (*) or just enjoying the beauty of it all! Quiet, peaceful haven convenient to downtown Aiken, Augusta, GA, and not too far from Columbia, SC. Amenities include full kitchen, washer & dryer, grill on back deck! Lovely small wedding venue! Convenient to Aiken area horse / equine facilities! *Lifejackets mandatory & available on site.

Sep 22 – 29

R2,378 ZAR per night

Guest favorite

Home in Chappells

4.95 out of 5 average rating, 145 reviews

Greenwood Lake Front, FirePit, Outside Kitch, Dock

Our place is unlike any other on the lake! The home is fully stocked and includes kayaks, pedal boat and lilly pad for your enjoyment. We have a dock and firepit. You will have no need to go anywhere else while you are here, as Camp Q has so many things to offer. The outside kitchen has 2 grills and a fridge. You’ll love my place because of the outdoors space, and the ambiance. My place is good for couples, solo adventurers, families (with kids), big groups, and furry friends (pets).

Nov 28 – Dec 5

R5,773 ZAR per night

Guest favorite

Home in Lexington

4.97 out of 5 average rating, 127 reviews

Lakefront home on Lake Murray with private dock

Lakefront home on Lake Murray in Lexington, SC on over 1/2 an acre, 166 feet of waterfront with deep water, private dock, and entertainment space- perfect for an unforgettable vacation or weekend. Entire home for rent-4BR, 3 Bath +2 half baths, 2 sofa sleepers, sleeps 12. Breathtaking kitchen & large living space, perfect for the entire family. 2 single person kayaks, outdoor grill, 65 inch and 55 inch TV, washer/dryer, and fast wifi. Master suite with a lavish bathroom and soaking tub.

Oct 28 – Nov 4

R9,227 ZAR per night

Guest favorite

Home in Santee

4.97 out of 5 average rating, 140 reviews

Santee lakefront home, big water right off I-95

Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

Dec 8 – 15

R10,077 ZAR per night

Guest favorite

Home in Inman

4.95 out of 5 average rating, 102 reviews

Maggie's Lake House

Private - Quiet and secluded neighborhood on Lake Bowen with dock & lake access. Enjoy spacious house with private 20x40 in-ground swimming pool, dock for fishing and boating, large decks & charcoal grill make for a great BBQ day! 2 kayaks provided! If you plan to bring your own boat to use from Maggie's dock, contact the Lake Bowen Warden Office to obtain boat sticker. Boat rentals are also available. Starting June 15, 2021-Spartanburg County Occupancy tax is 3% for each night.

Mar 1 – 8

R6,129 ZAR per night

Guest favorite

Home in Easley

4.9 out of 5 average rating, 276 reviews

“Lake House Paradise” Waterfront Oasis

“Lake Paradise” is exquisitely furnished with 2 bedrooms and 1 and a half baths. Your Master Suite has its own screened in porch with private lake access. Wake up from your master suite to views from your bed of the water. Your en suite Master Bathroom has a large luxury marble shower. You will spend many hours of relaxation and peace in the most desirable location in the southeast. Visit Greenville SC's downtown just 15 minutes away. Clemson football Stadium is 20 miles away.

Sep 22 – 29

R2,885 ZAR per night

Guest favorite

Home in Anderson

4.99 out of 5 average rating, 178 reviews

Lake Escape

This is the perfect lake house for your next family vacation, Clemson football game, or just a long weekend at the lake! Enjoy full access to Lake Hartwell with a private dock and swimming area. The house is located just 20 minutes from both Clemson and Anderson and also just 5 minutes from Portman Marina. Kayaks do not come included with the house but can be rented if inquired about ahead of time. Come enjoy some nature, relaxation, and fun at the Lake Escape!

Dec 16 – 23

R2,459 ZAR per night

Guest favorite

Home in Prosperity

4.99 out of 5 average rating, 135 reviews

Anchors Aweigh

You'll enjoy this small cabin located less than 2 miles from Dreher Island State Recreation Area. The views from the living area and kitchen are breath-taking. You can sit on the dock & watch the sun set or take your boat out just a few hundred yards to watch the sun rise. This location is great for swimming & a dock is available so you can bring your boat. There is also great fishing from the dock and on a boat. This will provide an unforgettable vacation!

Aug 4 – 11

R2,770 ZAR per night