Vacation rentals in La Mesa

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Top-rated vacation rentals in La Mesa

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Las Cruces
4.91 out of 5 average rating, 118 reviews

Apache’s Retreat w/ HOT TUB & Pool table

Our kid and pet friendly retreat welcomes you to this unique in-the-city barn-dominium, where ranch-style views meet modern comfort. Overlooking our beautiful livestock some friendly sheep, this home offers a peaceful country vibe just minutes from everything you need. We’re located just minutes from Red Hawk and Sonoma Ranch Golf Courses, and at the first exit to White Sands National Park — where we’ve got sleds ready for you to enjoy the dunes! Update: 2 baby goats just born, feed is availabl

Top guest favorite
An inviting outdoor space features a sparkling heated pool surrounded by comfortable lounge chairs. Palm trees and landscaping enhance the private backyard atmosphere. The home is visible in the background, illuminated as twilight sets in, creating a tranquil setting for relaxation.
Home in Las Cruces
4.89 out of 5 average rating, 140 reviews

Sunsets In Sonoma W/Heated Pool! Pet Friendly

Experience luxury living in one of Las Cruces’s most upscale and desirable neighborhoods. Seconds away from Sonoma Ranch golf course and Country Club. You’ll enjoy magical sunsets while swimming in our year round heated pool. Large, completely enclosed back yard for privacy and pets. Complete with games and ping pong table.A stand alone Casita is available for an additional fee, including separate climate control TV and a queen sized sofa sleeper (there is no bathroom in casita).Vacation awaits!

Top guest favorite
An aerial view of a Pueblo Style home is presented, showcasing a serene pool surrounded by a spacious outdoor area. The home is set against a backdrop of rolling hills and a cloudy sky. Desert vegetation is seen throughout the landscape, enhancing the natural beauty.
Home in Las Cruces
4.97 out of 5 average rating, 179 reviews

Desert Oasis with Pool

Pueblo Style home on 1+ Acre with Pool! This charming 4BR/2BA Pueblo Style home features stunning details throughout. Gorgeous saltillo tile in the living areas with beautiful wood beam accents, and a kiva-style fireplace for cozy winter nights. The primary suite offers direct access to the covered patio for summer dips in the pool and evening Sunsets. The 4th bedroom is huge and could be used as a second living area. The pool is not heated but will be open and cleaned all year. Sorry no pets.

Guest favorite
A warm-colored exterior of a one-story home is highlighted by evening sunlight. Lush green trees and desert plants are arranged around the entrance, while a gravel driveway leads up to the front door. A subtle rainbow can be seen in the sky, adding a serene touch.
Home in Las Cruces
4.84 out of 5 average rating, 193 reviews

The Alamo on Ocotillo

Enjoy this secluded desert oasis at the Alamo on Ocotillo. This fabulous spacious home is nestled in a quiet neighborhood conveniently located less than 2 miles from the university. Relax in the seasonal pool, enjoy time with family and friends in the various cozy outdoor spaces and take in some shopping in old Mesilla. Numerous travelers love to explore the Dripping Springs trails with an invigorating day hike. You'll find this home to be the peaceful "get away" you are looking for.

Top guest favorite
A vibrant yellow casita is framed by a rocky landscape and native vegetation. Large windows and a covered porch are visible, inviting natural light. The casita's exterior showcases a blend of rustic charm and modern design, set against a clear blue sky.
Guesthouse in Las Cruces
4.98 out of 5 average rating, 246 reviews

Casita De Cuervo

Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Top guest favorite
The exterior of the guesthouse features a welcoming entrance with a turquoise door framed by two wooden columns. A small seating area with two chairs is positioned on the porch, accompanied by potted plants and a tiled floor. The sky above displays a gentle blend of blue and white hues.
Guesthouse in Mesilla
4.97 out of 5 average rating, 410 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Top guest favorite
A geodesic dome structure features a light-colored exterior with a distinctive multi-faceted roof. A welcoming entrance is flanked by potted plants and a simple pathway, leading to a door adorned with seasonal decorations. Surrounding desert landscaping adds to the setting's natural beauty.
Dome in Chaparral
4.98 out of 5 average rating, 364 reviews

Desert Dome Retreat: Near El Paso & Las Cruces

Escape to the Desert Dome: Your Peaceful High-Desert Retreat Unplug at this unique dome getaway in quiet Chaparral, NM! Perfect for stargazing and relaxation, yet minutes from city amenities. Outdoor Gateway: Easy access to local hiking/biking, plus day trips to many National/State Parks. Pet-Friendly: Includes a private, fully fenced back area for your pets to play safely (please keep pets leashed outside the fenced area). Book your serene New Mexico escape today!

Top guest favorite
A bright interior features a queen bed adorned with geometric patterned bedding. Adjacent to the bed, two armchairs offer comfortable seating. A small loft area with a twin bed is visible overhead. A mirror and lamps provide additional lighting in the room.
Tiny home in La Mesa
4.98 out of 5 average rating, 243 reviews

Little House with Private Patio and Hot Tub

Our guesthouse is located on historic Highway 28, also known as the Don Juan de Onate Trail, which connects El Paso and Las Cruces. It is one of the area's most scenic routes. You can find breweries, multiple wineries, and the famous Chopes restaurant and bar along the route. The highlight of the 10-mile drive from our little house in San Miguel to historic Mesilla takes you through unique canopies of pecan trees, in the largest pecan-producing county in the nation.

Top guest favorite
A charming path leads to the entrance of the guest house, framed by blooming flowers and greenery. Decorative plants line the walkway, while a rustic wooden chair sits invitingly on the porch. The structure features adobe-style architecture under a clear blue sky.
Guesthouse in Las Cruces
4.94 out of 5 average rating, 144 reviews

1 bed cute casita near NMSU, pet friendly

Amazing details throughout this small but mighty space. You have all you need for a quick trip or a longer stay. 1 bedroom with a queen, full-sized kitchen, living room, and dining space as well as a fully fenced, pet-friendly yard. Be immersed in local culture with Talavera tile and Saltillo floors as well as vigas and rough-hewn ceilings and accent walls. The guest house is close to the main house but completely separate and private. Off-street, private parking.

Superhost
A bright and airy living space features a blend of modern and vintage elements. A dining table is elegantly set with vibrant decor, while yellow accent chairs provide a pop of color. A cozy blue sofa is positioned nearby, alongside a window adorned with cheerful curtains.
Home in Mesilla Park
4.93 out of 5 average rating, 389 reviews

One bedroom casita in Mesilla Park with hot tub

This unique place has an ambiance all its own. Located a few minute drive from historic old Mesilla and walking distance to a local coffee shop, Mexican restaurant, and a pizza restaurant. Mesilla plaza, and bars are only a few minutes drive away. The building has stainless steel new appliances and dual refrigerated air mini splits, one in the living room, and one in the bedroom. Please note there is a train that occasionally travels near the neighborhood.

Superhost
A spacious living area features a large gray sectional sofa with decorative cushions. A wooden coffee table sits in front, while light fixtures illuminate the room. The kitchen area is visible in the background, showcasing white cabinets and a decorative tile backsplash.
Home in Las Cruces
4.87 out of 5 average rating, 313 reviews

4 Bedroom Contemporary Model home

This fully-furnished modern home is perfect for weekend getaways or longterm stays. With 4 bedrooms and plenty of space The Dove Escape offers the comfort of home with a luxury feel. This stylish modern space is perfect for families, groups, or anyone seeking a retreat at the end of long day in Las Cruces or a break from the road. The Dove escape is minutes from NMSU and the University Corridor with all it has to offer.

Top guest favorite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guesthouse in Mesilla
4.99 out of 5 average rating, 273 reviews

Casita de Colibrí | Hot Tub • Walk to Old Mesilla

Escape to Casa de Colibrí, a private Southwest-inspired casita just a short walk from the historic Old Mesilla Plaza, restaurants, cafés, shops, and local attractions. Relax in your private hot tub, unwind on the peaceful patio, and enjoy a comfortable stay with fast Wi-Fi, a cozy bed, and thoughtful amenities. Whether you’re here to explore Las Cruces or simply relax, Casa de Colibrí is the perfect home away from home.

Popular amenities for La Mesa vacation rentals