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Apartment vacation rentals in La Mesa

Find and book unique apartments on Airbnb

Top-rated apartment rentals in La Mesa

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Top guest favorite
A charming casita exterior features a light-colored facade with green shutters. A tiled staircase leads to the entrance, flanked by vibrant landscaping. A garage door is visible, and a pathway is lined with plants, set against a clear blue sky.
Apartment in Greater North Park
4.96 out of 5 average rating, 161 reviews

Modern Spanish Casita. Sunny & Quiet with Kitchen!

Hello! I'm Steven, your Airbnb Superhost. I am dedicated to making your stay in San Diego comfortable and relaxing while you enjoy the amazing activities this city has to offer. Balboa Park and the Zoo are at your doorstep, along with an outstanding variety of restaurants. The airport, Petco baseball Park, Sea World, and beaches are a 15-min drive away. See “Getting Around” for more info. Whether you're here for work or fun, I am happy to offer suggestions and make the most out of your stay!

Guest favorite
The living area is designed with a comfortable gray sofa and a glass coffee table set upon soft carpeting. A modern blue armchair adds a pop of color. A flat-screen TV is mounted above an elegant fireplace, framed by decorative vases and shelving.
Apartment in Sherman Heights
4.89 out of 5 average rating, 143 reviews

Apartment near Downtown, Balboa, Coronado Island

Well laid out studio apartment with full kitchen, views of downtown and the Coronado bridge, WIFI. Shared patio area has gas grill, fire pit, and picnic table. Free street parking in front of house (I've never had to park more than a block away). Just a few blocks from great coffee shops, groceries, and bars. 1 Mile from Petco Park and Gaslamp in Downtown San Diego. 3 Miles from the San Diego Zoo. 4.5 Miles from the Hotel Del Coronado on Coronado Island (Best Beach in San Diego!)

Superhost
A spacious sleeping area is presented with a king-sized bed topped with white linens and fluffy pillows. A wooden headboard adds a warm contrast, while a nightstand with a lamp is positioned nearby. Large windows allow natural light to fill the room, enhancing the minimalist decor.
Apartment in Gaslamp Quarter
4.84 out of 5 average rating, 1,669 reviews

At Mine | Central Suite in the Gaslamp Quarter

This unit is a meticulously renovated historical hotel suite, designed by the renowned Italian firm Pininfarina, located in Downtown San Diego. Nestled in the vibrant Gaslamp Quarter, you'll find yourself in the midst of nightlife with an array of restaurants and bars in close proximity. The suite provides private and spacious accommodations catering to both vacationers and business travelers. Its features include a comfortable king-sized bed, a smart TV, central AC, and a mini-fridge

Top guest favorite
A modern living area features a deep blue sectional sofa with a red accent pillow. A stylish red chair adds a pop of color. Natural light floods the space through large sliding glass doors, which open to a small outdoor area. A well-equipped kitchen is visible in the background.
Apartment in South Park
4.95 out of 5 average rating, 311 reviews

Apartment54

This amazing apartment is part of a newly constructed, three-story home and includes plenty of closet space, AC, and views of the Coronado bridge. The kitchen is equipped with everything you need, including cooking supplies and a dishwasher. There is a small, semi-private front yard, shared washer/dryer (free), ample street parking, and plenty of other amenities . Close to all metro areas, Apartment54 is the perfect location for Comic-Con, Pride, or any other San Diego convention.

Top guest favorite
A bedroom is equipped with a metal bed frame featuring a floral-patterned quilt. Two bedside lamps cast soft light, and wall art in calming colors adds a touch of design. Sliding glass doors reveal outdoor access to a private patio area with furniture.
Apartment in La Mesa
4.98 out of 5 average rating, 174 reviews

Lovely Hideaway Studio by Village-Private Patio

Enjoy the cool vibe at this unique rustic getaway tucked back on a tree-lined hill 5 minutes above City of La Mesa Village, 20 minutes from downtown San Diego. The studio is on the ground floor of our two-story house. We live on the 2nd floor, and the studio is it's own completely private space. 5 miles to San Diego State University; 16-20 miles to San Diego beaches; 10 miles to Downtown San Diego; 15 miles to Sea World San Diego; and 13 miles to the World Famous San Diego Zoo!

Guest favorite
A lush garden path leads through vibrant greenery, featuring blooming roses and various colorful flowers. Tropical palm trees rise in the background, and the exterior of the house is painted in a soft hue, creating a welcoming atmosphere in the outdoor space.
Apartment in Cherokee Point
4.88 out of 5 average rating, 242 reviews

Private Studio close by North Park

Fiber WIFI, twin bed, TV (Roku & Netflix), microwave, fridge, hotplate, toaster, coffee maker, desk, office chair, armchair, folding table, iron & board. No pets please. Quiet, clean, central location. Free offstreet parking. Walk to University Ave eateries, shops, buses. See Host Guidebook. 1 mi to 30th St/North Park, 10 min drive to Balboa Park, Downtown, Airport. #7, 10 & 215 bus to downtown. Near I-I5, 805, I-8 freeways. Check-in: Lockbox. Cleaned & Disinfected for Your Safety.

Top guest favorite
A spacious studio features a large bed with decorative throws, complemented by a cozy chair and a small dining table. Tall windows allow natural light to illuminate the room, while neutral-colored curtains add warmth. A wardrobe provides additional storage alongside tasteful artwork.
Apartment in Serra Mesa
4.97 out of 5 average rating, 393 reviews

Anna’s modern & private San Diego guest studio!

Welcome to Anna's Getaway! Recently updated, beautifully detailed, clean, modern & spacious studio, private entrance, patio, A/C & heating, Tesla Solar System & free parking! High ceilings! Family friendly: Infant travel crib, high chair, toys & baby items. WiFi, Netflix and cable TV. Fully equipped kitchenette. Shower & bathtub. Washer & dryer. Centrally located in a quiet, safe & peaceful neighborhood, walking distance to playgrounds & parks! Whole house water filtration system!

Guest favorite
Apartment in Kensington
4.91 out of 5 average rating, 265 reviews

Studio with kitchen, city center

Bright and quiet Kensington studio — a peaceful retreat for couples or solo travelers just minutes from all San Diego has to offer. Nestled on a quiet, tree-lined street, this thoughtfully designed studio offers comfort and calm with a touch of local charm. Enjoy a plush bed and well-equipped kitchen — all within walking distance of Kensington’s beloved cafés and neighborhood restaurants. Quick freeway access makes it easy to explore beaches, Balboa Park, and downtown.

Guest favorite
A spacious lounge area features a large, L-shaped gray couch, a contemporary glass coffee table, and a flat-screen TV mounted on the wall. A fireplace with a dark mantel adds warmth, and light enters through the black-framed windows that lead to a private outdoor space.
Apartment in La Mesa
4.93 out of 5 average rating, 355 reviews

A Little Bit of Luxury in La Mesa! Private & Gated

Relax and stretch out on your king size bed or take a short stroll to La Mesa Village to take in the new shops, bars & restaurants. Enjoy your large lounge with smart tv & fireplace and while away the evening on your fully lit deck. The delights of downtown San Diego, beaches, zoo & airport are only a 15-20 minute drive away. Within walking distance to La Mesa Blvd Tolley stop. Apartment & parking for 1 vehicle is private & gated with plenty of on-street parking.

Guest favorite
A serene sunset view is captured with soft hues of purple, pink, and orange streaking the sky. Silhouetted hills create a calming backdrop, while the dimming light gently transitions the scenery into evening.
Apartment in Spring Valley
4.88 out of 5 average rating, 169 reviews

Comfy, Cozy Flat With Pool & Spa!

Our flat has a patio that enjoys great sunsets. We are freeway close to all, easy in and easy out!! You’ll love the place because of the comfy bed, space, patio and access to pool and spa. Also, the yard can be enjoyed for relaxing, eating, bonfires, horseshoes and cornhole. An adjoining space is also an AIRBNB studio suite. Great for traveling friends or as an alternative place to consider for your stay. Look for Foemer man Cave with Pool And Spa.

Guest favorite
An open living space is highlighted by a large sectional sofa and a round coffee table. The neutral-toned decor includes a colorful area rug. A dining table with two chairs is visible, while the kitchen area features a minimalist design with essential appliances.
Apartment in Little Italy
4.91 out of 5 average rating, 203 reviews

State & Fir (Little Italy Loft, Free Parking)

Ultra Minimal, Sunlit Bi-Level Loft In The Heart Of Little Italy—A Bright, Aesthetic Escape For Slow Mornings And Cozy Evenings. Enjoy Exposed Brick, High Ceilings, Beautiful Art, And An Airy Open Floor Plan. Step Outside To Trendy Cafés, Restaurants, Wine Bars, Farmers Markets, And Waterfront Park. Just Minutes To The Convention Center, Concerts, And The Trolley. Includes One Free On-Site Parking Spot And Free Laundry. Live Like A Local.

Guest favorite
A dining area features a large, light-colored table surrounded by six green chairs. A potted plant adds a touch of greenery, while a pendant light hangs above. Natural light enters through a large window adorned with soft curtains, enhancing the space’s openness.
Apartment in Valencia Park
4.94 out of 5 average rating, 158 reviews

Newly Remodeled Modern Apartment

This 2 bedroom, 1 bathroom apartment is located in Valencia Park San Diego, offering a variety of popular attractions. Your family will be close to everything when you stay at this centrally-located place. 4.9 Miles to Downtown San Diego 7.5 Miles to the San Diego International Airport 5.2 Miles to the San Diego Zoo 4.9 Miles to Petco Park 10 Miles to Seaworld

Popular amenities for La Mesa apartment rentals

When is the best time to visit La Mesa?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceR1,818 ZARR1,784 ZARR1,818 ZARR1,835 ZARR1,869 ZARR1,869 ZARR1,954 ZARR1,869 ZARR1,852 ZARR1,937 ZARR1,954 ZARR1,869 ZAR
Avg. temp15°C15°C16°C17°C18°C20°C21°C22°C22°C20°C17°C14°C

Quick stats about apartment rentals in La Mesa

  • Total vacation rentals

    Explore 30 vacation rentals in La Mesa

  • Nightly prices starting at

    La Mesa vacation rentals start at R510 ZAR per night before taxes and fees

  • Verified guest reviews

    Over 1,380 verified reviews to help you choose

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wi-Fi availability

    30 of La Mesa vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across La Mesa rentals

  • 4.7 Average rating

    La Mesa stays receive an average rating of 4.7 out of 5 from guests

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