Villa vacation rentals in James Island
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Top-rated villa rentals in James Island
Guests agree: these villas are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for James Island villa rentals
Private villa rentals
Villa in Kiawah Island
4.97 out of 5 average rating, 86 reviewsLagoon view villa with office, easy walk to beach!
Oct 9 – 16
Villa in Kiawah Island
4.93 out of 5 average rating, 96 reviewsClean & Comfortable! Steps to the beach!
May 15 – 22
Villa in Seabrook Island
4.83 out of 5 average rating, 59 reviewsPrivate island villa with luxury resort amenities!
Oct 15 – 22
Villa in Seabrook Island
4.97 out of 5 average rating, 59 reviewsBeautiful and Spacious 2 Bedroom Courtside Villa!
Jan 3 – 10
Villa in Seabrook Island
4.9 out of 5 average rating, 31 reviewsUpscale Villa, Amenity Included! Dog Friendly
Nov 8 – 15
Villa in Folly Beach
4.84 out of 5 average rating, 61 reviews83 Waters Edge - Comfy Cool - Pool
Aug 18 – 25
Villa in Seabrook Island
4.85 out of 5 average rating, 33 reviewsSeabrook Golf View Villa: Pickleball, Pool & Bike
Oct 9 – 16
Villa in Seabrook Island
4.92 out of 5 average rating, 52 reviewsNewly Remodeled Villa, 5 Minute Walk to Beach
Feb 26 – Mar 5
Luxury villa rentals
Villa in Kiawah Island
5.0 out of 5 average rating, 26 reviewsOcean Front! Beach is steps away. Clean and Crisp!
Oct 5 – 12
Villa in Isle of Palms
4.96 out of 5 average rating, 52 reviewsLuxury Isle of Palms Home Steps to Beach with Pool
Feb 28 – Mar 7
Villa in Seabrook Island
4.9 out of 5 average rating, 10 reviewsLuxury Seabrook Isl Beach Condo
Nov 23 – 30
Villa in Isle of Palms
5.0 out of 5 average rating, 11 reviewsCarolina Saltaire | New Decor | Beach 40 Yards
Mar 22 – 29
Villa in Seabrook Island
Seaside Therapy - An iTrip Vacations Home
Aug 25 – Sep 1
Villa in Kiawah Island
5.0 out of 5 average rating, 15 reviewsOceanfront Windswept Villa
Aug 23 – 30
Villa in Sullivan's Island
4.57 out of 5 average rating, 21 reviewsHaven by AvantStay | Luxury Beachfront Retreat
Nov 17 – 24
Villa in Kiawah Island
5.0 out of 5 average rating, 18 reviewsLuxury Penthouse 2 BR 3 Bath Villa with Ocean View
Dec 27 – Jan 3
Villa rentals with a pool
Villa in Seabrook Island
4.61 out of 5 average rating, 28 reviewsSpacious 1BR | Balcony | Pool |
Dec 8 – 15
Villa in Folly Beach
4.5 out of 5 average rating, 34 reviews3BR 2nd-Floor | Pool | Dock | Elevator
Dec 3 – 10
Villa in Seabrook Island
5.0 out of 5 average rating, 5 reviewsStunning Water Views Renovated Modern Oasis
Feb 15 – 22
Villa in Seabrook Island
4.96 out of 5 average rating, 23 reviewsUpscale, Private,Breathtaking Views
Feb 20 – 27
Villa in Johns Island
4.73 out of 5 average rating, 26 reviewsDog friendly villa on 8th hole of golf course
Sep 5 – 12
Villa in Isle Of Palms
4.78 out of 5 average rating, 36 reviews7C Seagrove - Sweetgrass
Nov 26 – Dec 3
Villa in Johns Island
Tranquil 1BR in High Hammock Villas
Dec 28 – Jan 4
Villa in Seabrook Island
New place to stayA+ Coastal Escape - Club Access
Nov 22 – 29
Destinations to explore
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- Rentals with a patio James Island
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