House vacation rentals in James Island

Find and book unique houses on Airbnb

Top-rated house rentals in James Island

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Charleston

4.98 out of 5 average rating, 113 reviews

Waterfront Privacy, heated infinity pool, location

Be prepared for a truly eye-opening, out-of-this-world experience! Booking this home will change the way you view your next vacation - literally! This is a one-of-a-kind Lowcountry home. Every detail in this home has been laid out just for you to arrive and immediately go into relaxation mode. There are amenities included for the adventurous outdoor-lover and for the unrivaled nightlife seeker Charleston boasts. And, this home is centrally located to Folly Beach and downtown Charleston-$20 Uber.

Sep 12 – 19

R19,257 ZAR per night

Guest favorite

Home in Charleston

4.95 out of 5 average rating, 145 reviews

Historic Kitchen House - South of Broad (Charming)

The Rutledge Kitchen House is located at the southernmost tip of the peninsula in the historic "South of Broad" neighborhood and is surrounded by many antebellum mansions. Walk to the Battery, Rainbow Row, King Street, the Calhoun Mansion, the Heyward Washington House, shops, museums, and restaurants. Stroll to White Point Garden to see the sunset over the harbor. We are one of the few short term rentals in the historic district licensed by the City of Charleston License # OP2018-00159

Aug 29 – Sep 5

R12,912 ZAR per night

Guest favorite

Home in Charleston

4.89 out of 5 average rating, 269 reviews

The Island Hideaway

This little gem is an edition we built as a duplex. The Hideaway is very basic, totally private, and super clean. It's perfect for a quick getaway and you can't beat the price and location! We're right in between historic downtown Charleston and the eclectic Folly Beach. We designed the Hideaway to be the a rustic little haven that anyone can call their own. The little Hideaway is not the Hilton, but we have all the basics to give you a safe, quiet and cozy resting place for your vacation.

Dec 19 – 26

R2,153 ZAR per night

Guest favorite

Home in Charleston

4.99 out of 5 average rating, 338 reviews

Peaceful Haven -5 miles to Folly Beach or Downtown

Welcome to Peaceful Haven! We live in Oregon, but visit often to spend time with our grandchildren. You will find our house fully-stocked-we have stayed in many Airbnbs, and want to make sure you have what's needed, without being burdened with our belongings. LOCATION: Our home is located right between Charleston and Folly Beach - 12 minutes/5 miles to each. ISSUES? Our son & daughter-in-law live right around the corner, and care for the home. CITADEL: 2+ Bridges EV Charger on site.

Nov 12 – 19

R4,175 ZAR per night

Guest favorite

Home in Johns Island

4.88 out of 5 average rating, 397 reviews

Charleston, SC-2 BR Guest Suite w/ Separate Entry

**One of the few Airbnb’s with a legal permit in Charleston, SC. Just 15 minutes from downtown Charleston, SC. Free legal parking on site! 1 bedroom guest suite plus an additional bedroom. Own private and separate entrance. Comfortably hosts four. Folly Beach a short drive from this safe neighborhood & 2 miles from legendary Angel Oak. Guest access to swimming pool. Complimentary coffee/coffee maker, cable TV, water bottles & juice, refrigerator. Rental License # BL012621-10-2018

Apr 7 – 14

R2,188 ZAR per night

Guest favorite

Home in Charleston

4.91 out of 5 average rating, 133 reviews

Make Yourself at Home

Brick ranch, conveniently located between Downtown Charleston and Folly Beach, 5 minutes to King Street, 20 minutes to Mt. Pleasant and 30 minutes to airport. Full house with 3 bedrooms, 2 bathrooms, open kitchen, dining room and large living room with big screen tv. A screened porch, fenced in backyard, washer & dryer , on site parking for 4 vehicles. Walking distance to 2 playgrounds, tennis court, wildlife sanctuary, state park and a great view of Fort Sumpter and the city.

Jan 1 – 8

R3,169 ZAR per night

Superhost

Home in Charleston

4.99 out of 5 average rating, 141 reviews

Chic Southern Stay

Located in one of Charleston’s most desirable locations of James Island, this adorable home is the perfect blend of modern elegance and cozy comfort. It is only a 10 minute drive to Downtown Charleston and a 12 minute drive to Folly Beach. Whether you are attending one of the city’s amazing festivals, seeking to explore Charleston’s rich history, or planning a fun beach weekend trip, it is truly a great location for all that Charleston has to offer.

Jul 11 – 18

R3,804 ZAR per night

Guest favorite

Home in Folly Beach

4.97 out of 5 average rating, 172 reviews

The Folly Haven

Welcome to your vacation get away on “The Edge of America” Folly Beach. The Beach Haven is the perfect place for couples, friends and family to kick off their shoes, shed the stress of daily life and melt into the relaxed bohemian beach vibe that is unique to Folly Beach. Just a five minute walk to dip your feet in the sand or stroll two blocks to Center Street and enjoy the shopping, eclectic dining and vibrant night life with live music.

Jan 13 – 20

R2,758 ZAR per night

Guest favorite

Home in Charleston

4.92 out of 5 average rating, 332 reviews

Welcome to Anchors Aweigh! Home Away From Home

We invite you to relax and enjoy our spacious guesthouse conveniently located just off Folly Rd on James Island in a safe and quiet neighborhood. Remodeled in 2020. 6 miles to Folly Beach and 5 miles to historical downtown Charleston. Within walking distance to many restaurants and stores. Our home provides the comfort of home away from home. Very clean and well stocked. Private entrance and designated parking for two vehicles.

Aug 19 – 26

R3,868 ZAR per night

Superhost

Home in Charleston

4.82 out of 5 average rating, 373 reviews

Cozy and Comfy Between Downtown and Folly Beach

Perfectly situated between Folly Beach and Downtown Charleston our newly renovated home is the best location for those wanting to explore Charleston and enjoy the beach. The home is one unit in a 2-unit duplex. There is 1 Bedroom with a queen bed, a queen-size pull-out bed in the living room and 1 bathroom. There is a small kitchenette in the living area. Enjoy a small patio. There is room for 2 cars in the private driveway.

Jul 10 – 17

R2,848 ZAR per night

Guest favorite

Home in Folly Beach

4.83 out of 5 average rating, 133 reviews

Luxury Beach Front Pet Friendly

Located minutes from the Morris Island Light House, indulge in the epitome of seaside luxury at our beachfront vacation home, where every detail has been thoughtfully curated to ensure a perfect retreat. Located directly on Folly Beach's pristine shores, this 2023 to the studs renovated cottage seamlessly blends opulence with comfort, offering a harmonious escape for you, your loved ones, and even your four-legged friends.

Aug 26 – Sep 2

R15,975 ZAR per night

Guest favorite

Home in Charleston

4.93 out of 5 average rating, 259 reviews

Stylish & Stunning Home Close to City & Beach

This is an incredible home that has just been renovated and updated throughout. Enjoy the openness of the great room perfect for getting together with family and friends. The private back deck is shaded by oak trees and a great place to enjoy your morning coffee. Very comfortable accommodations centrally located with all Charleston has to offer from Beaches to historic landmarks & nightlife.

Feb 8 – 15

R5,841 ZAR per night