Vacation rentals in Irene

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Top-rated vacation rentals in Irene

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A garden area features a decorative trellis adorned with soft lights, providing a warm glow in the evening. Lanterns are placed along the pathway, contributing to a serene atmosphere. The well-maintained grass and greenery create a welcoming outdoor space.
Home in Sioux Falls
4.96 out of 5 average rating, 28 reviews

Relaxing Retreat with Cozy Patio

Welcome to your perfect Sioux Falls getaway! This spacious home offers 2 fully equipped kitchen, ideal for family meals or entertaining. Relax in the stylish theater room for movie nights or cozy up by the fireplace upstairs. Outside, enjoy the patio with fireplace, outdoor grill, and plenty of space for gatherings. Perfect for family get-togethers or friends' hangouts, whether for work or fun. Enjoy all the comforts and amenities for a memorable stay. Book now and experience Sioux Falls! Enjoy

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Top guest favorite
A modern riverside retreat is surrounded by landscaping featuring natural stones and wooden pathways. The exterior showcases large windows and a sleek design, while a spacious patio extends out, encouraging outdoor enjoyment and relaxation in the peaceful setting.
Home in Larchwood
5.0 out of 5 average rating, 89 reviews

A River House Near Sioux Falls

Get out of the city, to this riverside retreat. Enjoy the oversized patio/firepit watching the sunset, listening to the Big Sioux River right below your feet. Relax inside by the fireplace of this recent luxury remodel, 3 king bedrooms, 3 bathrooms,on 1 level is rare to find, gorgeous kitchen and oversized island to host those closest to you. Nestle in upstairs the loft and enjoy the views of this river valley. Never to far from all amenities the big city has to offer, but perfect to unplug

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Guest favorite
The entrance features a light blue door adorned with a decorative wreath. A nearby window allows natural light, while a small potted plant and flowers brighten the entrance. Two black chairs are positioned on the steps, enhancing the welcoming appearance.
Cottage in Viborg
4.95 out of 5 average rating, 111 reviews

Parkview Cottage ~ Charming Tiny Home ~ Queen Bed!

Step into the comfort of this charming Parkview Cottage nestled in the very heart of Viborg, SD. It promises a relaxing retreat allowing you to walk to the booming Main St., with excellent Danish restaurants, shops, and attractions. Once you are done sightseeing, retreat to the lovely 1915 renovated home whose cozy design will satisfy your every need. ✔ Comfy Queen Bed + Sleeper Sofa ✔ Open Studio Living ✔ Full Kitchen ✔ Patio ✔ Smart TV ✔ High-Speed Wi-Fi ✔ Free Parking See

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Top guest favorite
The split-level home is set against a backdrop of greenery, featuring a stone chimney and an American flag. An attached garage is visible alongside the well-maintained gravel driveway. Nearby, a large barn adds to the rural landscape, creating a calm and serene environment.
Home in Wakonda
4.98 out of 5 average rating, 218 reviews

Quiet split level farm home w/ garage parking

Welcome to the Gregoire Farm. Our home is a recently remodeled split level located on our family farm. It has 3 bedrooms and two baths as well a sofa bed. Park your car in our two car garage. Great place for a larger group to have plenty of room. A little ways off the beaten path but worth a little extra drive. 15 min drive to Vermillion, 20 min drive to Yankton and 35 minutes to Sioux Falls. If you are looking for a quiet place to yourself please consider us. Non-smoking, pet free home.

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Top guest favorite
Cabin in Yankton
4.98 out of 5 average rating, 53 reviews

Secluded Ridgeway Hideout | Cozy, Porch, Fireplace

The Hideout on Ridgeway, a peaceful escape tucked away in nature yet close to everything you came for. 5 minutes to Gavin’s Boat Ramp on Lewis & Clark Lake, this spacious retreat is perfect for lake days, family gatherings and weekends with friends. Sip your coffee on the screened-in porch, cozy up by the fireplace, or settle in for movie night on the 75” TV in the loft. The home is fully stocked—linens, coffee, and cooking essentials are all provided—so you can arrive, unpack, and relax.

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Top guest favorite
A lower level entertainment room features a gray sofa adorned with a red blanket and a decorative pillow showcasing the initials 'USD.' A ping pong table and a foosball table are visible, with a university flag displayed on the wall.
Home in Vermillion
4.99 out of 5 average rating, 128 reviews

Townhouse in Vermillion close to USD

Relax with all your family & friends as you enjoy the wonderful town of Vermillion during your stay in this comfortable and spacious duplex. Conveniently located close to USD's campus, restaurants, and shopping. Walk down and enjoy a USD event. Or take the family to the park. Closely located to Prentis Park where you can cool off at pool, play on the playground or basketball courts and enjoy the beautiful picnicking areas. This home is sure to accommodate for a fun stay during your visit.

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Superhost
Cabin in Yankton
5.0 out of 5 average rating, 3 reviews

Lakeview Cabin at DJ's Resort

Private cabin with a huge patio overlooking the gorgeous Lewis & Clark Lake. This space offers a private and cozy getaway for up to 10 guests, just minutes away from all that the Lewis & Clark state recreational area has to offer. Fully furnished and stocked with everything you need to kick back & relax (linens, dish and silverware, appliances, & more). The patio has a grill, propane fire place, and furniture for outdoor lounging. Ask about our lakeside fun rentals!

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Top guest favorite
The exterior of a ranch-style home is showcased, featuring a well-maintained lawn with green grass and decorative landscaping. A wide driveway leads to a two-stall garage with multiple windows. The house is framed by trees and shrubbery, offering a welcoming presence.
Home in Sioux Falls
4.97 out of 5 average rating, 444 reviews

3 Bed/2 Bath Southside executive manor

Welcome to your peaceful Southside retreat! This 1,488 sq ft ranch offers comfort and convenience with 2 king bedrooms, 2 baths, and a business suite with twin bed and Wi-Fi. Enjoy a cozy living room with 65” TV, fenced yard, deck, and 2-stall garage. Dogs welcome (max 2; see rules under "Other Details to Note"). Sleeps 5 max — 5th guest +$50/night. Ideal for families, professionals, and travelers seeking quiet relaxation near Sioux Falls attractions.

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Top guest favorite
Barn in Hartington
4.97 out of 5 average rating, 39 reviews

Cozy Red Barn Cabin with Silo, Scenic Views

Enjoy a peaceful retreat in this cozy red barn with a silo, Featuring two upstairs bedrooms, a half bathroom on the main floor, and a full bathroom upstairs.Relax on the screened-in porch, warm up by the fire pit, and explore nearby trails and the stocked with fish Willow Pond.Inside, you’ll find plenty of charming antique touches paired with modern amenities, creating a unique and welcoming space.Perfect for a quiet getaway with comfort and scenic views!

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Guest favorite
A serene landscape at dusk features a calm body of water reflecting the colorful sky. Silhouettes of trees are visible along the shoreline, with a distant silo standing against the horizon.
Farm stay in Lesterville
4.92 out of 5 average rating, 36 reviews

Farm house by Lesterville

This is a 4 bedroom farm house on a working cattle farm started by my husbands grandfather in rural Yankton county. The land includes lakes where hunting could be arranged and there are many local CRP acres in the area as well. Located on a paved road 1.25 miles from Lesterville, SD. Local area: 25 miles from Yankton, SD, 20 miles to Lewis and Clark Lake, 50 miles to Pickstown, SD. Enjoy the piece and quiet after a long day on the lake or hunting.

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Top guest favorite
An outdoor gathering space showcases a propane fire pit surrounded by several white Adirondack chairs. A hot tub sits nearby, illuminated by hanging string lights, creating a cozy atmosphere. Decorative signs add character to the rustic red wooden structure in the background.
Cabin in Yankton
4.98 out of 5 average rating, 90 reviews

Eclectic Cozy Cabin w/ GameRoom, HotTub & FirePit

Escape to Cedar Ridge, a unique 3,200 sq. ft. cabin in Yankton's wooded hills. Perfect for groups, this 5-bedroom retreat blends luxury with nostalgic vintage vibes and is designed for guests who appreciate originality and crave a truly unique experience. Enjoy the 10-person hot tub, a full game room with a bar and a spacious deck with a smoker and gas grill. It's an unforgettable getaway for rest and play, just minutes from Lewis & Clark Lake.

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Top guest favorite
Home in Beresford
4.95 out of 5 average rating, 20 reviews

The Acreage: Country Stay for 12, 30 min to USD

SoDak Stays is proud to present The Acreage! • Restored 1919 farmhouse on 10 acres near Beresford, SD • Peaceful country escape • 30 mins to Vermillion, 35 mins to Sioux Falls • Sleeps 12 — perfect for families • Pet-friendly • Bunk beds, high chair & booster seat • Cozy outdoor seating + propane grill • Surrounded by cornfields & classic barns for a true farm feel Book your stay at The Acreage today!

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