Vacation rentals in Harrisburg

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Harrisburg

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Apartment in Sioux Falls
4.97 out of 5 average rating, 159 reviews

Cozy Flat - near hospitals & universities

Cozy, clean and chic apartment down a flight of stairs in lower level of triplex near Augustana University, University of Sioux Falls, North American Seminary, Sanford & Avera Hospitals, and Midco Aquatics Center. Centrally located close to downtown & an easy drive to Empire Mall & Great Plains Zoo. Electric fireplace. Access to deck with bistro lighting and fire pit in backyard. Clean and safe neighborhood. Same floor laundry access. WiFi and ChromeCast streaming. On street parking available.

Top guest favorite
The exterior of a charming house is presented, featuring a distinct yellow front door framed by large windows. Lush green landscaping and a welcoming pathway lead to the entrance. A flag is displayed nearby, enhancing the home’s inviting curb appeal.
Home in Sioux Falls
4.98 out of 5 average rating, 129 reviews

The Mustard Door

Our charming 2 bedroom house is the perfect place for your trip to Sioux Falls! The house has an attached garage and tiled walk-in shower. During your stay you can also enjoy a full kitchen and a patio for outdoor fun. Our Airbnb is within walking distance to Sanford Medical Center, both colleges, as well as the Midco Aquatic Center. If night life is your thing, Downtown Sioux Falls and the Denny Sanford Premier Center are both within 3 miles from the front door! The ideal place for any guest!

Top guest favorite
The kitchen features modern appliances, including a stainless steel oven and microwave, set against a backdrop of tiled backsplash. White cabinetry offers ample storage, while a dark countertop highlights kitchen essentials. Natural light filters through nearby windows, creating a bright cooking space.
Home in Sioux Falls
4.99 out of 5 average rating, 232 reviews

Vintage Hospitality | Mid Century Retro Retreat

Get the authentic vintage "retro ranch" experience along with the best modern amenities and proven hospitality at the original Mid Century Retro Retreat in central Sioux Falls. You have the whole house, with a fully-equipped kitchen, laundry, bathroom, 2 private bedrooms and a den with a futon. You're just a few blocks away from Augustana University, Sanford Hospital, University of Sioux Falls, Midco Arena, shopping, and restaurants. Downtown and Avera Hospital is a 5-minute drive away.

Guest favorite
A cozy living room features a large leather sofa adorned with decorative pillows, complemented by a light wooden coffee table. Natural light fills the space through multiple windows, highlighting the textured area rug beneath. Decorative plants add a touch of greenery to the inviting atmosphere.
Guest suite in Sioux Falls
4.96 out of 5 average rating, 735 reviews

Casalona: Cozy Designer-Curated Central Retreat

Charming mid-century guest-suite within a home in the heart of Sioux Falls, steps from Augustana and close to Sanford and downtown. Guests have private access to the front suite of the house, including two bedrooms, a spacious living room, and full bath. With natural light, cozy furnishings, and greenery, the space feels inviting. Styled with modern and vintage pieces, this thoughtfully designed home offers a peaceful, inspiring place to stay for travelers seeking comfort, style, and home.

Top guest favorite
Home in Sioux Falls
4.97 out of 5 average rating, 230 reviews

Secluded getaway, 10 min from SF

Get away from the busyness just outside of Sioux Falls. A full private apt in a new home in a country neighborhood. Parking spot and private walkway to a separate entrance on the lower level walkout. Relax with a split king adjustable bed and warm up with a steam shower for two. Full kitchen, Sitting area w/a futon bed, Carpet free, Polished cement with in-floor heat, Central Air & Ceiling Fans, Wooded backyard. Good Earth State Park 1/2 mile, Dntn Sioux Falls 10 miles, I-90 10miles.

Top guest favorite
Guest suite in Sioux Falls
4.98 out of 5 average rating, 241 reviews

Luxury Suite • Private Yard • Hot Tub • King Bed

Welcome to The Chic Suite — a fully private, luxury guest suite designed for rest, convenience, and quiet comfort. Featuring a plush king bed, rainfall tile shower, secluded fenced yard, and your own hot tub, this space is perfect for business travelers, quick overnight stays, and couples looking for a peaceful retreat in northwest Sioux Falls. Tucked behind the main home garage with its own entrance, walkway, and outdoor space — you’ll have complete privacy during your stay.

Top guest favorite
A private hot tub is showcased, illuminated with soft blue lights. It is surrounded by a wooden privacy fence, ensuring an enclosed atmosphere. The lid is partially opened, reflecting calm water, inviting relaxation in a serene outdoor setting.
Home in Sioux Falls
4.97 out of 5 average rating, 406 reviews

Inspiration Ranch-HOT TUB/lower unit/SUPER CLEAN!!

PLEASE READ!! Welcome to Inspiration Ranch, located in a safe, new neighborhood with quick access to restaurants, shopping, and stores. This private lower unit has its own entrance via the garage stairs. Enjoy full access to the entire space featuring tall ceilings, large windows, and an open, inviting layout. You’ll feel right at home the moment you arrive—perfect for relaxing or exploring the area! Guests are always happy and comfortable here! ✨ PLEASE READ MY REVIEWS!

Top guest favorite
The treehouse features a distinct green metal roof and multiple windows for natural light. Surrounding wooden decks offer various viewing levels, providing a panoramic view of the snowy landscape. The structure is elevated on stilts, surrounded by trees, enhancing the sense of seclusion.
Treehouse in Valley Springs
4.91 out of 5 average rating, 397 reviews

Lookout Loft Treehouse

Welcome to the Lookout Loft Treehouse! Find a retreat in this peaceful hilltop oasis just a short 20 min drive out of Sioux Falls, SD. Sleep in the clouds on your dreamy pillow top mattress, wake up to stunning 360 degree views overlooking the surrounding countryside. Enjoy a cup of coffee on the wraparound deck, a propane fire on the mid-level deck and a dip in the hot tub at ground-level. Space includes a kitchenette, bathroom, and sleeping quarters, with AC and heat.

Top guest favorite
A spacious kitchen features modern appliances and white cabinetry, complemented by a large island with seating for six. Natural light filters through the window blinds, creating a warm ambiance. A cozy seating area is visible in the corner, enhancing the room's inviting layout.
Home in Harrisburg
4.95 out of 5 average rating, 226 reviews

Some Brothers House with SIX private bedrooms!

Every day is special at our spacious country getaway! Host your family, friends, reunion, or retreat! A beautiful place to experience one night or an extended stay! Enjoy the outdoors, or spread out inside! Our rustic, industrialist home boasts of cornfields, fire pit, stars, and minutes to Venues Meadow Barn and Canton Barn, local grocery, and 10 minutes to Sioux Falls or Canton! Be sure to check out the Venue for your special events! airbnb.com/h/estatevenue

Top guest favorite
The exterior of the ranch-style home is illuminated at night, showcasing a spacious driveway leading to a three-stall garage. Bright outdoor lighting highlights the well-maintained landscaping, with shrubs and small plants bordering the entrance.
Home in Sioux Falls
4.97 out of 5 average rating, 423 reviews

3 Bed/2 Bath Southside executive manor

Welcome to your peaceful Southside retreat! This 1,488 sq ft ranch offers comfort and convenience with 2 king bedrooms, 2 baths, and a business suite with twin bed and Wi-Fi. Enjoy a cozy living room with 65” TV, fenced yard, deck, and 2-stall garage. Dogs welcome (max 2; see rules under "Other Details to Note"). Sleeps 5 max — 5th guest +$50/night. Ideal for families, professionals, and travelers seeking quiet relaxation near Sioux Falls attractions.

Guest favorite
Home in Sioux Falls
4.95 out of 5 average rating, 296 reviews

The Cozy Place

Welcome to our Cozy Place, close to everything in Sioux Falls. When you step into this basement apartment style unit, you can’t help but appreciate the fresh and updated look with a warm and inviting feel. This house is built as a triplex therefore is separated into 3 apartments that operate as Airbnb stays. This listing is for the newly remodeled basement unit / apartment, and you will have your privacy and enjoy the comforts it provides.

Superhost
A distinctive A-frame house is set against a clear blue sky. Large glass panels create an open feel, surrounded by well-maintained landscaping featuring lush grasses, ornamental plants, and a mix of trees, offering a peaceful retreat in a natural environment.
Home in Canton
4.83 out of 5 average rating, 223 reviews

Relaxing Riverview Cabin with Scenic Hot Tub

Relaxing Riverview House with stunning view and HOT TUB. Take advantage of our great location and quiet setting nestled in the trees along the Sioux River. Small town services are only 10 minutes away and city shopping and entertainment is less than 20 minutes. You will have access to the Sioux River for canoeing, kayaking, fishing or just hiking by the river. (Please provide your own outdoor recreation equipment)

Popular amenities for Harrisburg vacation rentals