Guesthouse vacation rentals in El Cajon

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in El Cajon

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Guesthouse in La Mesa

4.97 out of 5 average rating, 117 reviews

San Diego Newly Built Private Guesthouse (Sleep 5)

Newly built one-bedroom private guesthouse with view of Cowles Mountain and separate street entrance. Living room has queen futon and side chair that folds out into small cot-sized bed. A 50" smart TV with YouTube TV. Free high-speed Wi-Fi. Kitchen with new refrigerator, stove, oven, microwave, dishwasher, toaster, and Keurig coffee machine. Bedroom has queen bed and 40" smart TV. Bathroom has large shower and electronic bidet. New washer/dryer. Allow small pets up to 35 lbs. for $20 fee.

Oct 13 – 20

R2,848 ZAR per night

Guest favorite

Guesthouse in La Mesa

4.97 out of 5 average rating, 130 reviews

Da Hui Hut-Beachy home/La Mesa’s best view and spa

Da Hui Hut is a very private oasis uniquely situated at the top of San Diego county's magnificent Mt. Helix. At roughly 1,300 feet above sea level, Mt. Helix is the crown jewel of natural landmarks in the area. The landscape provides bountiful views, and the large deck is positioned perfectly to see it all. It feels like you're on top of the city! Inside, guests will encounter Californian and Hawaiian inspired decor as they collide with wooden walls to compose a symphony of color and good vibes.

Jun 6 – 13

R3,028 ZAR per night

Guest favorite

Guesthouse in El Cajon

4.99 out of 5 average rating, 152 reviews

Modern mountain guest house. Incredible views

Neighboring San Diego, quaint country living with incredible views minutes from everything, breathtaking sunsets, 20 mins to beach, close by hiking trails, and only 3 minutes hop on the freeway. Full Kitchen, Laundry, and Living area and with beautiful furnishings, a perfect home away from home. Whether traveling for work or play we have had guests stay for a conference in San Diego or just to visit friends and hit the beach a few days, we look forward to you loving our home as much as we do.

Nov 12 – 19

R3,337 ZAR per night

Guest favorite

Guesthouse in San Diego

4.91 out of 5 average rating, 114 reviews

Charming Granny Flat Near SDSU & Transit Center

This is a charming studio in San Diego, located .5 m from the trolley, SDSU, Alvarado Hospital, and 17 min from Downtown. It is clean, cozy and is a true home away from home. Also, .3 mi to Ralph's (groceries) and 1 mi from Trader Joe's, Eureka Burger, Poke and TheBrokenYolk. Separate entrance, shared back yard,&grill. Hi-speed internet, Netflix,LiveTV+HBO. It has Queen bed, and a sofa with a pull-out bed, kitchen (stove, oven, and microwave) and washer/dryer (EV220 plug available upon request)

Jun 4 – 11

R2,469 ZAR per night

Guest favorite

Guesthouse in La Mesa

4.92 out of 5 average rating, 205 reviews

Fig Tree Bungalow

Enjoy your stay in San Diego in this newly renovated guesthouse. Centrally located about a mile from Hwy 8, Hwy 125, and the Grossmont Trolley Station & Transit Center. Only a 15-20 minute drive to downtown, the airport, the beaches, and most of San Diego's other popular tourist attractions. This cozy, two-story, detached unit is located behind my home, and has its own private entrance and partitioned yard for your enjoyment. There's plenty of street parking directly in front of the house.

Jun 15 – 22

R2,344 ZAR per night

Guest favorite

Guesthouse in El Cajon

4.96 out of 5 average rating, 131 reviews

Mt Helix Studio Loft with Mountain Views

Mountain Views: Freshly renovated, quiet and spacious studio loft in private neighborhood. Close to coffee shops, grocery stores, and quick access to major highways. 500 sqft open concept. Laundry, Fast Internet, Cable TV and streaming services. Additionally, if you like oranges and avocados we grow them on the property (Seasonal of course). We also have a chicken coop and fresh eggs on request. Security Deposit Hold and Signed Short-term Rental Agreement Required as we live on the property.

Sep 25 – Oct 2

R2,845 ZAR per night

Guest favorite

Guesthouse in La Mesa

4.99 out of 5 average rating, 166 reviews

SDCannaBnB #1 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our casita is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our casita has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our casita is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Jul 10 – 17

R2,648 ZAR per night

Guest favorite

Guesthouse in El Cajon

4.98 out of 5 average rating, 190 reviews

Fletcher Hills - modern 1 BR.Easy, no step access.

** 48 hours between check-ins. Thorough cleaning and sanitizing.. Four night minimum stay. Dogs ONLY are welcomed on a case by case basis. They must be house trained and are not permitted on any furniture. If you instant book, you must contact me about your pet within 24 hours. Smoking is permitted in the outside areas - patio, gazebo, yard. Easy freeway access helps any commute to downtown and area attractions. Having your own vehicle is the best way to get around..

Sep 23 – 30

R2,210 ZAR per night

Guest favorite

Guesthouse in El Cajon

4.93 out of 5 average rating, 165 reviews

San Diego Bohemian Poolside Lounge @ Eden East

Retreat to a private 1 bedroom poolside apartment. Not just a place to stay, but a retreat to recharge mind, body & spirit and forget everything currently happening on the "outside". Perfect escape for locals and tourists alike...ideal for spending some time with friends and loved ones soaking up the chill vibes of our little hidden gem in the East County of San Diego. Strong WIFI. Shared pool. By reserving, we assume you've read entire ad and agree to all house rules.

Nov 23 – 30

R3,117 ZAR per night

Guest favorite

Guesthouse in La Mesa

4.99 out of 5 average rating, 132 reviews

Stunning Guest House 15 min. from Zoo, Downtown

Stunning guest house that's 15 minutes to San Diego Zoo + downtown San Diego and 18 minutes to a beach. Unique private property with mid-century and one-of-a kind furniture in a comfortable living space. Enjoy IPAs on your private deck or coffee in bright Fiesta cups, watch TV while leaning back in the handcrafted Nicaraguan rocker or the 1950s Danish slipper chair. The cottage also has a comfy queen-sized bed. Like eclectic? This place exudes it.

Sep 20 – 27

R2,990 ZAR per night

Guest favorite

Guesthouse in La Mesa

4.9 out of 5 average rating, 142 reviews

La Cabana

Perfect getaway for the wandering individual, couple, or young family. This rustic casita is surrounded by beautiful mountain and ocean views! Enjoy swimming in the pool, stargazing, lounging, or casual day trips around San Diego (All the amenities are shared with the main house) . The casita has one queen bed and a sofa bed, small kitchenette. Plenty of parking in driveway. Please read entire listing for details.

Dec 29 – Jan 5

R2,992 ZAR per night

Guest favorite

Guesthouse in Chula Vista

4.95 out of 5 average rating, 475 reviews

Private Casita in Great Eastlake Neighborhood

This room is a "casita" (seperate living space) away from the house. It has a private entrance with a cypher lock on the door. The room has new carpet, new tile, and queen size bed. The Eastlake neighborhood is very safe and very quiet. We are located about 20 mins from the beach, downtown San Diego, and San Diego international airport. This location is only 2 miles from the Otay Ranch Mall.

Sep 5 – 12

R1,807 ZAR per night