
Family-friendly vacation rentals in Downtown
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Downtown
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Mission Hills - Cozy Canyon Condo
Situated in a cozy, quiet neighborhood with friendly neighbors, this cozy condo has it's own entrance and a beautiful view of a eucalyptus-filled canyon. Watch honey bees and hummingbirds flit through the trees and listen to wind rustling leaves from your private deck. Amenities include: •Queen bed •Private bath with shower •Refrigerator, microwave and basic kitchen supplies (note: not a full kitchen--no kitchen sink or stove) •Wifi (note: no TV) •Private, well-lit entrance down a small stairway (so not ADA accesible) Conveniently located in Mission Hills, one of San Diego’s oldest, safest neighborhoods sandwiched between historic Old Town and hip Hillcrest, you will be within: •Walking distance to UCSD Medical Center, Scripps Mercy Hospital, grocery stores, playground, park, trolley stop and many fabulous restaurants with a wide variety of cuisines and price ranges •A long walk or short bike ride to Balboa Park, San Diego Zoo, Old Town and the waterfront •A short drive or long bike ride to downtown, Petco Park, the beaches, Sea World and the airport •Two miles to all major freeways We would be delighted to welcome you to our fabulous canyon-side condo.

Stylish Little Italy Stay | Free Parking Near Bay
Our Spacious 2 Story, Beautifully Decorated Apt is the Perfect Home Away From Home for Families, Couples, Digital Nomad, or Solo Traveler Looking for a Comfortable & Convenient Place to Stay. Located in One of the Most Vibrant Neighborhoods in SD Little Italy is Known For its Restaurants, Cafes, & Local Shops. So Many Attractions! the Waterfront Park, CRSSD Festival, USS Midway Museum., Balboa Park, Petco Park, The Convention Center, Running/Bike Paths, The County Building. 1 Free Parking Spot

Canyon-view Modern One Bedroom Bankers Hill
Clean, modern design one bedroom ground-floor apartment with huge windows looking onto Maple Canyon and San Diego Bay. Ocean breezes fill the space. Building brand new in 2022 with fantastic location for walking to Balboa Park or local restaurants and cafes. Custom designed furniture throughout with whimsical artistic touches. In-unit laundry, A/C, dog friendly too! Great location in Bankers Hill with close proximity to Downtown, Little Italy, Airport, Hillcrest, and more. Welcome to San Diego!

Bright& Clean, Heart of Downtown Studio - Sleeps 4
This bright and modern studio apartment is the essential San Diego home base. The location is RARE and is within walking distance to the hottest neighborhoods in the Downtown area, the Zoo, Balboa Park and is also only a 10 minute drive from the beach. Bright, airy and stocked with all of the essentials, this space is perfect for small groups or work trippers looking to explore Downtown SD by staying in the heart of it. If you're looking to stay in a truly unique Downtown gem, look no further.

Spacious Historic Suite, 6 Blocks to Downtown!
Bright, spacious suite in historic home, blocks from downtown and across the street from urban-hip Golden Hill with it's eclectic eateries and coffee houses. Five minute drive or scooter ride to San Diego's historic neighborhoods of North & South Park, Balboa Park, Coronado Beach and the Zoo. Large studio includes Queen bed, Queen sofa sleeper and large attached outdoor patio, private entrance and ample street parking. Great for couples, friends and families of 2-4 people and for longer stays.

Trendy Studio, Natural Light - Heart of Downtown
Large studio with comfortable queen sized Murphy Bed, a love seat, private entrance and private bath. Located in Cortez Hill - walk to the nicest neighborhoods in downtown like Little Italy, Gaslamp, East Village, and the Embarcadero. There is no full kitchen, but there is a small refrigerator, small microwave, and a pot for heating water. This is an ideal space for solo travelers, couples, events at the Convention Center, Padres Games, great eateries, and the best of Downtown San Diego.

Stylish and Very EASY Walk to Gaslamp/Convention!
Welcome to San Diego's vibrant Gaslamp Quarter and PetCo Park neighborhoods! IDEALLY located, this unique home is STEPS to Convention Ctr, PetCo Park, & all of San Diego's best restaurants, shopping, & bars! FAST internet & easy access/self entry! 2 blocks from Petco .6mi from Convention Ctr Perfect for solo adventurers, couples, business travelers, & small groups (4 max). Parking recommendation: space.aceparking dot com (7th and Market within 3 blocks and cheap!) or Street parking.

Sunny Stylish & Central - Luxe Little Italy Studio
Located right in the heart of vibrant Little Italy is this sparkling Downtown studio filled with light, airy boho vibes and all the amenities you could need for a cozy stay. Whip up meals in the fully-equipped kitchen, snooze in the luxe king bed, soak up the sun on the lounge or sip your coffee at the chic café-style dining table. Ready to explore? Little Italy's buzzing restaurants, bakeries, and cafes are just steps away or take a quick 10-15 min drive to San Diego's top sights.

At Mine | Central Suite in the Gaslamp Quarter
This unit is a meticulously renovated historical hotel suite, designed by the renowned Italian firm Pininfarina, located in Downtown San Diego. Nestled in the vibrant Gaslamp Quarter, you'll find yourself in the midst of nightlife with an array of restaurants and bars in close proximity. The suite provides private and spacious accommodations catering to both vacationers and business travelers. Its features include a comfortable king-sized bed, a smart TV, central AC, and a mini-fridge

Downtown Cottage Minutes to Gaslamp & Petco Park
Welcome to your urban cottage just steps away from downtown San Diego! The Queen Anne Cottage combines brand-new renovations with historic charm. The Cottage has a private entrance so you can easily come and go and is located in quiet, family-oriented neighborhood in the Sherman Heights historic district just a few blocks from downtown San Diego. It is minutes away from the Convention Center, Petco Park, the Gaslamp District, the Coronado bridge, Balboa Park, and the San Diego Zoo.

Waterfront Loft | 1BR | Little Italy | Downtown
The local neighborhood is highly walk-able and perched along the San Diego Bay in Little Italy. Little Italy is the most vibrant neighborhood in downtown San Diego with a main street that abounds with restaurants, boutiques, craft beer, and wine bars all at your doorstep. This is a very urban location which brings a lot of urban noise. The unit sits adjacent the train and trolley line in the urban core. No parking provided, Ideal for guests without a car.

Modern Boho Loft in Heart of Gaslamp
Come stay in this modern bohemian loft located in the heart of Downtown San Diego. This loft is perfect for a couples vacation, friends night out, or traveling business people. The loft is surrounded by various restaurants, bars, nightclubs, coffee shops, and stores. Within walking distance to the Convention Center, Petco Park, and Seaport Village. Short drive from San Diego International Airport, SeaWorld, Zoo, Little Italy and Balboa Park.
Popular amenities for Downtown family-friendly rentals
Family-friendly home rentals with a hot tub

Santorini-Inspired Cottage w/ Hot Tub + Views

Colorful North Park Home | AC, BBQ, Private Office

Mountain View Retreat in Gated Estate (Hot Tub)

Urban Retreat

The Palms Villa Amazing Amenities Perfect Location

Dragonfly Cottage - In the Heart of San Diego

Bohemian Paradise Mid-City San Diego with SPA

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub
Family- and pet-friendly home rentals

Insta-worthy! 1 night/many nights, no min required

Modern bungalow w/beautiful kitchen

#1 LOCATION - Rare Luxury Home in Downtown

Golden Hill House, Gorgeous Skyline, Private Patio

Sunlit Studio Hideaway | Walk to Gaslamp & More

Romantic Private Garden Studio Near Downtown

San Diego at your doorstep

NEW Stylish❤️ of Downtown Little Italy w Parking/AC
Family-friendly home rentals with a pool

On park. 1 bed apt.has air & small kitchen+w&d

The BEST NEST Clean, peaceful, private, affordable

Private 1 BR Paradise retreat

Private Poolside Cabana

Comfortable & convenient accommodation @ San Diego

The Tiny Helix

Designer Luxury Rental With Pool

Birdsong Suite | Family-friendly getaway
Quick stats about vacation rentals that are family-friendly in Downtown
Total vacation rentals
Explore 750 vacation rentals in Downtown
Nightly prices starting at
Downtown vacation rentals start at R697 ZAR per night before taxes and fees
Verified guest reviews
Over 29,690 verified reviews to help you choose
Pet-friendly vacation rentals
Find 280 rentals that welcome pets
Vacation rentals with a pool
220 properties feature pools
Rentals with dedicated workspaces
520 properties have a dedicated workspace
Wi-Fi availability
740 of Downtown vacation rentals include wi-fi access
Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Downtown rentals
4.7 Average rating
Downtown stays receive an average rating of 4.7 out of 5 from guests
Destinations to explore
- Rentals with a beach view Downtown San Diego
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- Apartment rentals Downtown San Diego
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- Rentals with outdoor seating Downtown San Diego
- Rentals with beach access Downtown San Diego
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- Rentals with a fireplace Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Rentals with a fire pit Downtown San Diego
- Boutique hotel rentals Downtown San Diego
- Hotel rentals Downtown San Diego
- Family-friendly rentals San Diego
- Family-friendly rentals San Diego County
- Family-friendly rentals California
- Family-friendly rentals United States
- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Tijuana Beach
- Pacific Beach
- SeaWorld San Diego
- LEGOLAND California
- University of California San Diego
- Coronado Beach
- San Diego Zoo Safari Park
- Balboa Park
- La Misión Beach
- Oceanside Harbor
- Coronado Shores Beach
- Liberty Station
- Sesame Place San Diego
- Moonlight Beach
- Belmont Park
- Black's Beach
- Law Street Beach
- Torrey Pines Golf Course
- Santa Monica Beach
- Mission Beach
- USS Midway Museum