Vacation rentals in Cambridge

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Cambridge

Guests agree: these stays are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1
Top guest favorite
Home in Prophetstown
4.99 out of 5 average rating, 142 reviews

Spacious & Serene home in Prophetstown

Located a comfortable walk from the rock river & local Prophetstown shops. This unique home welcomes beautiful afternoon views, professionally designed rooms, and every day helpful amenities. Situated on the center of 3 lots, this house features a very spacious yard with lots of room for privacy. All while having instant direct access to Spring Hill rd. Which leads directly to the Quad Cities Metropolitan area.This home offers a versatile blend of comfort & function with every visit to the area

Top guest favorite
A hot tub is set on a deck overlooking the Mississippi River. The water bubbles gently, reflecting the serene landscape with trees lining the shore in the distance. The horizon features a slight view of buildings, enhancing the natural setting.
Home in Pleasant Valley
5 out of 5 average rating, 169 reviews

Mississippi River House

Now is a great time to stay in this completely furnished two-bedroom house directly overlooking the Mississippi River. The hot tub is amazing during the day and under the stars this time of year. Eagle watching in the winter is always entertaining while relaxing in the hot tub. This 1+ acre property is tucked away on a private dead end street, yet close to many great restaurants and shopping. If you're looking for a romantic getaway this house has everything you need for a wonderful time!

Guest favorite
A tranquil view of the Rock River is presented, featuring a wooden dock extending into the water. Lush trees line the shore, and the sky displays soft blue hues with wispy clouds. The calm water reflects the natural surroundings, creating a serene atmosphere.
Cabin in Moline
4.94 out of 5 average rating, 231 reviews

Riverfront Firepit, Kayaks, Huge Deck

Firepit ready for relaxing nights by the river. Kayaks included for warm days Wake up to sweeping Rock River views, sip coffee on the wrap-around deck, paddle out in the kayaks, and end your evening by the firepit as the sky glows at sunset. This eclectic riverfront bungalow blends vibrant décor with cozy comfort and seamless indoor-outdoor living. Perfect for girls’ weekends, fishing trips, romantic escapes, or peaceful fall getaways — just steps from the water and minutes to shops and dining

Top guest favorite
Home in Geneseo
4.99 out of 5 average rating, 104 reviews

Groovy 60s Themed House

Enjoy this completely remodeled home that’s a step back in time. Filled with 60s decor, style and flare with modern amenities and the comfort of home. Step into the lower level to shoot some pool or relax with tunes on the record player. A spacious deck overlooks a wooded area for a relaxing quiet night. The Airbnb house is owned by C&S Antique Mall - which is open daily for your shopping fix. Just minutes from historic downtown and close to restaurants and shopping, the location is perfect.

Top guest favorite
The living area features a spiral staircase leading to the upper level, a gas fireplace set within a stone wall, and large French doors allowing bright natural light. A cozy seating arrangement includes a patterned chair next to a side table, with a decorative area rug adorning the floor.
Cottage in Le Claire
4.97 out of 5 average rating, 534 reviews

Mississippi Overlook Cottage. Dogs welcome.

Settle into a fully renovated 1910 cottage perched on a steep hill above Buffalo Bill Cody’s original homestead. Enjoy a charming park right behind you and stunning river views in front. The cottage comfortably accommodates up to six guests. - The cottage is located on a steep hill. - You will hear trains, as LeClaire is a river and train town. 🚂🌊 - This is a wooded property, so expect sticks, leaves, and bugs. 🌿🐞 - There are many steps. 03/24/26. Cody Rd is under construction.

Top guest favorite
A spacious living area features large windows that allow for natural light, showcasing scenic views of the outdoors. Modern furniture, including a sectional sofa and accent chairs, is arranged around a central coffee table. A spiral staircase is visible, leading to an upper level.
Cabin in Princeton
4.96 out of 5 average rating, 156 reviews

Private & Modern. Near river and wildlife refuge!

Experience the outdoors in comfort from this modern cabin, situated next to the 2200 acre Princeton Wildlife Management Area, and the nearby Mississippi River. It is ranked as the most “Wish Listed” Iowa listing of 2025 on Airbnb. Are you into hiking, biking, fishing, hunting, boating, or other water, winter, and summer sports? This cabin can support it all! Sit back and relax on the large deck while enjoying a coffee & the local wildlife, flora, & fauna of the Mississippi Valley Region.

Top guest favorite
The entrance features a welcoming porch with a ceiling fan and decorative lights. A white picket fence includes a painted flower sign, while steps lead to a green door framed by large windows. Rocking chairs are placed on the porch, inviting relaxation.
Cottage in Le Claire
4.97 out of 5 average rating, 240 reviews

Grasshoppers Guest House Too, cozy, cute, cottage!

This cozy cottage is 1000 sq. feet of charm. You are in the heart of downtown, historical Le Claire. Your home away has everything you will need for your stay. The porch overlooks downtown, nestled in with views of the Mississippi River. Shops, dining, brewery & distillery all to enjoy. visitleclaire.com has monthly activities & festivities. Birthplace of Buffalo Bill Cody & home to Mike Wolfe on American Pickers. You may even see him unloading treasures at his shop Antique Archaeology!

Guest favorite
A wooden deck extends over the serene water, showcasing a calm river reflecting the greenery on the opposite bank. Potted plants sit on the edge of the deck, surrounded by an inviting natural landscape.
Cottage in Rock Island
4.87 out of 5 average rating, 234 reviews

Rock River Escape

Enjoy your coffee, a nice bbq dinner, glass of wine, a good book, or just enjoy the sweeping views out of this cute bungalow. With 180 ft of unobstructed river views and river access, bring your fishing poles and get ready to relax and enjoy watching the water slowly drift by at this centrally located bungalow in a quiet residential neighborhood. Firepit with firewood provided. No parties allowed so please do not inquire about them.

Top guest favorite
A serene outdoor space is captured, featuring a swing hanging from a tree and a landscaped area with flowers. Adjacent to the water, seating options are visible on a deck, offering a relaxed view of the river, complemented by greenery and a stone pathway.
Cottage in Port Byron
5 out of 5 average rating, 147 reviews

River Current's Cottage

River Current's Cottage is a hidden gem tucked on the banks of the Mighty Mississippi River. This cozy cottage has magnificent views of the river, no matter what time of year you chose to stay the views & cottage will offer you endless relaxation and enjoyment. With wonderful options for dining just minutes away in Port Byron or driving a few more minutes to LeClaire, IA you can truly make this a relaxing getaway.

Guest favorite
Bungalow in Bettendorf
4.87 out of 5 average rating, 225 reviews

River Retreat

Welcome to our River Retreat. This house is situated at the end of a quiet dead end road right on the Mighty Mississippi River. Fully furnished with Wifi, washer/dryer and everything you need for a quiet and relaxing get away. Enjoy the river views from the deck and 3 season porch or relax in living room with a movie. Extra furnishings include a fire pit and charcoal grill. Book your stay today!!!

Top guest favorite
A decorative wreath is displayed on a door, featuring a sign that reads 'Kewanee House.' The wreath is adorned with greenery, small flowers, a miniature door, and cotton bolls, creating a charming and inviting entryway.
Home in Kewanee
4.98 out of 5 average rating, 192 reviews

Little House in Kewanee

Lovely Farmhouse Style 2 bedroom home located across from park. Newly decorated with fully equipped country style kitchen. The master bedroom has adjustable queen size bed while second bedroom has 2 twin beds. The house is great for a family, two couples or a girls weekend to Historic Bishop Hill or destinations Psycho Silo, Goods Furniture or Horse shoes at Blackhawk College East.

Top guest favorite
A cozy living area features a gray sectional sofa with decorative pillows. A flat-screen smart TV sits on a shelf illuminated in purple tones, displaying various streaming options. Natural light enters through the window, while a door leads outside, enhancing the welcoming atmosphere.
Home in Moline
4.92 out of 5 average rating, 201 reviews

The Little Gem

Kick back and relax in this calm, stylish space. We have 1 bedroom with a queen bed, smart TVs and USB charging lamps. Feel free to prepare a meal in our stocked kitchen or prepare yourself a cup of coffee. This location is right off the Avenue of the Cities and is near grocery stores, restaurants and gas stations.

Popular amenities for Cambridge vacation rentals

  1. Airbnb
  2. United States
  3. Illinois
  4. Henry County
  5. Cambridge