Guesthouse vacation rentals in Tucson

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Tucson

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

A spacious sleeping area features a plush bed with decorative pillows, complemented by large floor-to-ceiling sliding glass doors that open to a lush backyard. A black-bottom pool is visible just outside, surrounded by manicured greenery, creating a serene oasis.

Guesthouse in Blenman-Elm

4.97 out of 5 average rating, 401 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in an infrared or hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies—lounge in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top guest favorite

A spacious studio features a queen-sized bed adorned with a soft coverlet. A curved red lounge chair complements the warm adobe walls and wooden ceiling beams. Natural light filters through large windows, illuminating the cozy corner with a beehive fireplace, enhancing the tranquil atmosphere.

Guesthouse in Peter Howell

4.96 out of 5 average rating, 860 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (1-19-2024) "59 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the Eucalyptus Suite Airbnb and the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Top guest favorite

A vibrant, sunlit patio area showcases colorful wall art on bright orange walls. A small table with two chairs sits beneath lush greenery, providing a perfect spot for outdoor dining. The space is adorned with various plants, enhancing the inviting atmosphere.

Guesthouse in Catalina Vista

4.95 out of 5 average rating, 426 reviews

Oasis: Casita Colibrí - Little Hummingbird House

Casita Colibrí is a lush desert oasis in the heart of Tucson flourishing with life. Tucked among fruit trees and gardens, this eco micro-farm is home to a pond, chickens, tortoise, friendly pets, and hummingbirds. Enjoy fresh eggs, meander garden paths, relax poolside, or watch the koi pond. Casa Colibrí isn’t just a place to stay—it’s a place to slow down, reconnect, and breathe in the beauty of the Sonoran Desert where peace and magic are woven into every corner of this special space.

Top guest favorite

A charming exterior view of the guest house is presented, featuring colorful potted plants arranged along the pathway. A cozy seating area with white chairs is visible beside the entrance adorned with a vibrant door, framed by warm lighting and lush greenery.

Guesthouse in Tucson

4.97 out of 5 average rating, 813 reviews

Private Tucson Desert Guest House Getaway

This guest house is a pleasant desert retreat in Northeast Tucson, nestled on a large property with spectacular views of the Catalina Mountains. Minutes from from Sabino Canyon, Mt. Lemmon, and close to sumptuous dining. Guests will enjoy a recently space which includes a kitchenette complete with a microwave, coffee-maker, toaster oven, refrigerator, and more. Large bathroom and closet. Also available are a pool, BBQ grill, outdoor seating, and play yard. Laundry available upon request.

Top guest favorite

A rustic adobe exterior is adorned with a wooden door framed by natural wood accents. Prickly pear cacti grow on either side, set against a textured adobe wall. Pebbles cover the ground, complementing the earthy tones of the structure.

Guesthouse in Armory Park

4.96 out of 5 average rating, 127 reviews

Adobe Carriage House downtown Chiminea+Ramada

This studio is spacious & comfortable. It is detached, secluded, on a quiet street, ample street parking and completely fenced in. The yard has a ramada with a table, chairs, string lights and a chiminea Inside, you’ll love the exposed adobe, skylight, and wood beam ceilings. The fully stocked kitchen is updated, with full size appliances. In the heart of Armory Park, it is close to 5-points, downtown, historic 4th Ave and Uof A. Ask me for dining, hiking, shopping and day trip recs!

Top guest favorite

A modern kitchen is showcased with wooden cabinetry and dark appliances. A spacious white countertop extends into a breakfast bar with two wooden stools. A door leading to the outside is visible, framed by natural light, creating an open and inviting atmosphere.

Guesthouse in Tucson

4.97 out of 5 average rating, 175 reviews

The Coop- Luxury guest house with ideal location

This luxury guest home was originally a chicken coop for a farmer over 60 years who owned the majority of the land in the area. With an addition and a complete renovation, we have designed this for the perfect vacation rental ideally located in Tucson. 15 minutes to Banner and the U of A. 10 minutes to Oro Valley or the freeway. The stylish guest home is separated from our home and designed with privacy in mind. Enjoy this brand new house for your stay with experienced hosts.

Guest favorite

The bright bedroom features a spacious bed with soft linens and two yellow accent pillows. Natural light fills the space through large windows, which overlook a serene outdoor area with cacti. Comfortable seating options, including armchairs and a round pouf, accompany the bed.

Guesthouse in Jefferson Park

4.94 out of 5 average rating, 521 reviews

Central and Stylish Midcentury Pool House

Our beautiful adobe pool house is a Tucson gem. Comfortable queen bed, fireplace, and stylish modern furnishings with large windows looking out to trees and sparkling pool. Vaulted ceilings and natural light make for a restful space. Located in historic Jefferson Park, it’s a midtown oasis close to the UofA and two blocks from the UMC/Banner Medical Center. Midtown/University location allows for convenient access to all of Tucson. *Newly improved high speed WiFi 11/1/2021

Top guest favorite

A refreshing outdoor pool is surrounded by a concrete deck with gentle curves, featuring a rock waterfall design at one end. The private Casita, with large windows, is positioned nearby, complemented by lush greenery and blue skies. A shaded area offers a comfortable retreat.

Guesthouse in Tucson

4.95 out of 5 average rating, 182 reviews

Private Casita in Casas Adobes

411sq ft private Casita just newly REMODELED! Sleeps up to 4. King feather bed & a pullout sleeper. Located just past a quaint garden where you can catch hummingbirds drinking. Private parking & entrance, just come and go. ASK ABOUT: Our other King Suite just feet away! Can sleep 2 more! Cool off in pool (rarely used by us), use outside patio (where cooking station is located, there's no kitchen in the casita). Min. from I-10 & stellar Tucson Biking Loop!!

Top guest favorite

An open layout is featured, showcasing a bookshelf filled with various books and plants. A spacious bed is positioned in a corner, while a bright door leads outside. A decorative window with colorful curtains and a table with a centerpiece are also visible.

Guesthouse in Tucson

5 out of 5 average rating, 276 reviews

Saguaro Courtyard Retreat near National Park

If you love nature this casita is just for you. Located 15 minutes from downtown and only a few minutes from stunning hiking and mountain biking trails in the National Park. The property is very much like a botanical garden with fruit trees filling up the back and a wide variety of succulents filling the front. The casita has its own private porch while the property shares two large communal patios with outdoor dining and a fire pit.

Top guest favorite

The vibrant blue exterior of the guesthouse is softly illuminated by warm lights, highlighting the welcoming entrance. A textured stone path leads to the door, flanked by a cozy seating area with two chairs and a small table, set amid the serene outdoor landscape.

Guesthouse in Sam Hughes

4.99 out of 5 average rating, 607 reviews

TREAT GUEST HOUSE Private, Quiet, Comfortable

Welcome to a one-of-a-kind guesthouse created by a Swiss-born professional photographer and freelance artist. This attractive open studio space is part of my "Gesamtkunstwerk" (entire body of work), still in flux. Featuring murals and curated pieces from across a lifelong creative journey. Thoughtfully designed with passion and purpose, the space offers both inspiration and comfort in the heart of Tucson.

Guest favorite

A spacious room features a comfortable full-sized bed with neutral linens, complemented by a plush round pillow. A wooden dresser with simple decor and a large mirror provide functionality. Natural light enters through the window, while a door leads to a small outdoor area.

Guesthouse in Tucson

4.92 out of 5 average rating, 443 reviews

Spanish Bungalow Casita with Private Patio

This one of a kind Spanish Bungalow is among the finest accommodations in Tucson. Nestled in the heart of Tucson, distinguished by modern amenities and historic character. The Spanish Bungalow is located walking distance from Downtown, the best Mexican restaurants in the city and minutes away from the U of A, and so much more. Come relax and enjoy the thoughtful privacy this bungalow has to offer.

Top guest favorite

The image displays a serene garden area, featuring a variety of lush plants and cacti. A pathway made of bricks leads towards a shaded patio, which is supported by brightly painted columns. The garden is designed with natural elements, creating a peaceful outdoor ambiance.

Guesthouse in Jefferson Park

5 out of 5 average rating, 166 reviews

Extra-Spacious 1BR Guesthouse Close to UA

Charming guest casita in historic mid-town neighborhood, perfect for short- or long-term stays. Its location 5-7 blocks from University of Arizona and Banner University Medical Center makes it super convenient for grad students, visiting professors and researchers, snowbirds, or vacationers. The nearby streetcar and bus routes provide easy access to downtown attractions.