Hotel vacation rentals in Saint Clair County

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Top-rated hotel rentals in Saint Clair County

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Top guest favorite

A spacious studio with high vaulted ceilings features a cozy seating area, a dining table, and a comfortable bed. Large industrial steel-frame windows allow natural light to fill the space, showcasing city views. The minimalist decor includes mid-century modern furniture and warm wood tones.

Hotel room in St. Louis

4.96 out of 5 average rating, 147 reviews

Chic Ultramodern Studio Loft w/ Designer Features

The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, a spacious walk-in closet, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, and bright 7’ industrial steel-frame windows with views of the tree-lined street and shops below. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Guest favorite

A spacious bedroom features a large bed with crisp white linens and a textured accent wall in deep blue. A flat-screen television is mounted on the wall, and a desk with a chair is positioned nearby. Natural light enters through a window adorned with simple curtains.

Hotel room in St. Louis

4.75 out of 5 average rating, 85 reviews

The West End by Cortex, Forest Park, BJC & Zoo

Welcome to The West End, your ideal retreat in the heart of the Central West End! Just steps away from charming attractions like forest park. Great amenities are: - Fast and stable fiber internet connection - Communal kitchen with 2 sets of range, ovens, fridges, microwaves, and dishwashers. - Complimentary coffee - Secured Gated Parking $10/Night - Hot Tub - Great patio space with seating and a gas grill - Complimentary Netflix, Hulu, Disney+, and ESPN+, where available and local TV channel

Guest favorite

A spacious open-plan living area features industrial-style concrete walls and ceilings. A modern kitchen with black stainless appliances and wood cabinetry is visible, alongside a cozy seating area with a brown leather sofa. Decor includes a triptych artwork depicting ocean waves, enhancing the minimalist aesthetic.

Hotel room in St. Louis

4.89 out of 5 average rating, 109 reviews

Chic Ultramodern Loft Suite w/ Designer Features

The Nash Loft is a stunning minimalist flat with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, a spacious walk-in closet, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, and bright 7’ industrial steel-frame windows with views of the tree-lined street and shops below. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Superhost

A bright bedroom is adorned with a light blue wall, creating a serene atmosphere. The spacious bed is covered with a decorative blanket, flanked by crisp white linens. A bedside table and a dresser provide practical storage, while a large window allows natural light to fill the room.

Hotel room in St. Louis

4.87 out of 5 average rating, 749 reviews

Blue Spruce Room Queen Bed at BnB in CWE!

A Lovely room in a historical St. Louis home! The Blue Spruce Room is on the 2nd floor, and has a recently renovated and beautiful bathroom complete with a walk-in rain shower right next to it. The room has a desk, chair, lamp, table, Amazon Fire TV with basically every major streaming App, newly installed hardwood floors, and a Queen sized-bed. The room has two large windows for plenty of natural light with heavy blinds for sleeping in! Full use of the kitchen upstairs is available!

Guest favorite

The spacious studio features high ceilings and large industrial steel-frame windows, allowing natural light to fill the room. A modern sofa and armchairs are arranged around a wooden coffee table. A dining area with seating is visible, complementing the minimalist design.

Hotel room in St. Louis

4.92 out of 5 average rating, 149 reviews

Chic Ultramodern Studio Loft w/ Designer Features

The Nash Loft is a stunning minimalist studio with 12’ ceilings + bright 7’ industrial steel-frame windows, a spacious open layout, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances and quartz countertops. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

A spacious living area features a large brown leather sectional sofa surrounding a wooden coffee table. A bright red accent chair complements the setting. The wall is painted dark, adorned with three framed black-and-white artworks. Exposed brick and wooden beams are visible in the backdrop.

Hotel room in St. Louis

4.75 out of 5 average rating, 4 reviews

Industrial Loft; 3 Bedrooms!

Perfect for Large Groups seeking an Urban Adventure; Retreats, Reunions, Bachelor & Bachelorette Gatherings.. Located near all Downtown St. Louis' Attractions! The Industrial Artist Loft portrays an open & spacious layout w/ 3 Bedrooms!!! Which includes 8 beds; accommodating up to 15 guests to sleep comfortably. Enjoy a vast living courters, one full bathroom and one full kitchen. Cook for yourselves with a stove, oven, microwave, fridge and freezer.. Utensils & Coffee provided!

Hotel room in St. Louis

New place to stay

Near Central West End | Free Breakfast + Pool. Bar

Stay smart, stylish, and sustainable in the heart of St. Louis Midtown. Just steps from Forest Park, SLU, and the Grand Center Arts District, Element St. Louis Midtown features sleek, apartment-style suites with full kitchens and eco-conscious touches. Unwind in the indoor pool, sip cocktails at the on-site bar, and start your day with free hot breakfast. With EV charging, a fitness center, and walkable hotspots nearby, this stay blends comfort, convenience, and a touch of luxury.

Guest favorite

The living area features exposed brick walls and large industrial windows, allowing natural light to fill the space. A modern leather sofa is paired with a geometric coffee table, while a dining table with place settings completes the inviting atmosphere. A cozy area rug adds warmth.

Hotel room in St. Louis

4.9 out of 5 average rating, 156 reviews

Gorgeous Ultramodern 2BR Corner Loft + Workspace

The Nash Loft is a stunning corner loft with two spacious bedrooms, two designer bathrooms with black stainless fixtures and frameless glass showers, 12’ ceilings, a comfortable workspace with high-speed internet connection, stackable washer + dryer, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

The exterior of the AC Hotel Central West End is displayed, featuring a modern six-story building with brick cladding and large windows. The entryway is accented with wooden slats, and a welcoming glass facade reflects the evening sky.

Hotel room in St. Louis

4.6 out of 5 average rating, 10 reviews

Walk to Forest Park + On-site Restaurant & Bar

Stay steps from Forest Park and the best of Central West End at AC Hotel St. Louis. With sleek European-inspired design, a vibrant lobby bar, and walkable access to top restaurants, museums, and nightlife, you’re perfectly placed for STL adventures. Grab a crafted cocktail, hit the 24/7 gym, or explore iconic spots like the Zoo and Art Museum—all just minutes away. Whether you're here for business, culture, or Cardinals baseball, this stay keeps you close to it all.

A spacious living area features a comfortable sofa and an ergonomic chair at a dedicated workspace. The room is well-lit with natural light from a large window, complemented by a television and a wooden dining table with seating.

Hotel room in St. Louis

4.47 out of 5 average rating, 32 reviews

Downtown Suite l Swim. Gym. Free Breakfast.

Welcome to Residence Inn by Marriott St. Louis Downtown, nestled in Missouri! We provide a great location in downtown St. Louis, spacious lodgings, and great facilities such as a pool and fitness center. Enjoy a daily breakfast buffet - on us! Then, head out to one of the nearby attractions, such as The Gateway Arch and St. Louis Zoo. ✔ Pool ✔ Fitness center ✔ Free breakfast ✔ Pet-friendly ✔ Indoor and outdoor fireplaces ✔ Mini-market ✔ Downtown location

Superhost

A spacious room features a King-sized bed adorned with a patterned throw, accompanied by a pullout sleeper sofa. Two pieces of wall art add a touch of color, while a large television and a dark wood cabinet provide functionality. Soft lighting enhances the inviting ambience.

Hotel room in St. Louis

4.9 out of 5 average rating, 917 reviews

King Redwood Bedroom at BnB in CWE!

This is the largest of the rooms we have at our CWE BnB - an historic house in St. Louis' premier neighborhood. It has one King sized bed, a pullout sleeper sofa, two back-to-back 45" 4K Smart TVs with Rokus, and bathroom and kitchen space shared with guests of other rooms on this floor. Within a short walk of the basilica and many bars and restaurants in the CWE!

Top guest favorite

The exterior of a historic Victorian house is presented, featuring a light-colored facade with decorative motifs around the windows. Lush greenery frames the entrance, with manicured hedges leading to the front steps. The building showcases multiple stories and distinctive architectural details.

Hotel room in St. Louis

4.97 out of 5 average rating, 73 reviews

Lafayette Square Inn - Lafayette Room

Lafayette square has the largest collection of renovated victorian houses in America and this is one of them. Dating to 1876, this historic home offers quality amenities. We are located near: America's Center Convention Complex - 2 Miles Bush stadium - 1.5 Miles Stifel Theatre - 1.4 miles Gateway Arch - 2.1 Mi Enterprise Center - 1.2 Mi Delmar Hall - 7 Mi