Boutique hotel vacation rentals in South Italy

Find and book unique boutique hotel rentals on Airbnb

Top-rated boutique hotel rentals in South Italy

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

The spacious suite features elegant decor with warm tones. A large bed is centered against a richly textured headboard. A seating area includes two red sofas and a small table. Wall sconces provide soft lighting, while natural light filters through a window with curtains.

Hotel room in Rome

4.87 out of 5 average rating, 244 reviews

Relais Santa Caterina - The Suites

The Relais Santa Caterina della Rosa is housed in a 16th-century palace, a former convent and the historic seat of the Conservatory of Santa Caterina. The Upper Suite is a unique, 90 sq. meter, totally frescoed location, its windows overlook directly in the hallway of the church below. Equipped with Wi-Fi, smart TV, fridge bar and wine cellar, air-conditioned, it is the ideal solution for families or small groups who choose a unique place, in the heart of the historic center for their stay.

Guest favorite

A spacious attic room features high wooden beams, enhancing the overall design. A comfortable bed is dressed in neutral tones, complemented by neatly arranged towels. A storage unit is positioned beside the bed, and the room is well-lit, creating a bright atmosphere.

Hotel room in Sorrento

4.96 out of 5 average rating, 209 reviews

Sorrento Historic Center-Attic without window

By staying at Palazzo Delle Grazie you will experience the magical atmosphere rich in history that only the historic center of Sorrento can offer you. The historic building that houses the facility has been entirely restored, used and designed to offer its guests all the comforts necessary for a pleasant stay. A rich continental breakfast is included in the reservation. Tourist tax of €4.00 per day per person not included in the price (from 1 April to 31 October) CODICE CUSR 15063080EXT0742

Guest favorite

A spacious bedroom is illuminated by soft lighting, featuring a large white bed with crisp linens. A green tropical mural adorns one wall, while a stylish yellow armchair and small side table create a cozy seating area beside a window with sheer curtains.

Hotel room in Pompei

4.97 out of 5 average rating, 159 reviews

Pompei Central - Deluxe Room #202

Situato vicino alla stazione Pompei Santuario e alla stazione Pompei Centrale (Trenitalia) e a pochi passi (500m) dalle rovine antiche di Pompei: la nostra struttura si trova nel cuore della città , vicinissimo al Santuario dedicato alla Madonna del Rosario. Pompei Central offre una Camera Matrimoniale con letto King size e bagno privato, Wi-Fi gratuito, aria condizionata e Smart TV - 50 pollici. A vostra disposizione troverete anche un parcheggio custodito con una tariffa di 15€ al giorno.

Guest favorite

A wooden countertop is featured, adorned with a vintage lamp, a guitar, and a green bottle. A floral arrangement in a glass vase adds a touch of color. A framed artwork and a sign reading 'ROME' complete the artistic space, which is illuminated by natural light from the window.

Hotel room in Rome

4.84 out of 5 average rating, 314 reviews

Del Falco - San Pietro Boutique Rooms

Del Falco -St. Peter's Boutique Rooms is located in the heart of Rome, and housed in a 17-century building. It's 1 minute walking from St Peter's Basilica and 300 metres from The Vatican Museum, Castel Sant'Angelo and Metro station. Every room has a contemporary style and vintage details. Each is fitted with a flat-screen TV and A/C. Rooms are equipped with private bathroom, bidet, shower or jacuzzi, free toiletries and a hairdryer. There's a lounge area. Free WI-FI.

Guest favorite

A spacious bedroom features a comfortable bed with neutral bedding and decorative pillows. A mirror reflects the room's light, while a bedside lamp and nightstand add functionality. Large windows offer natural light and access to a terrace, creating a bright and inviting ambiance.

Hotel room in Matera

4.9 out of 5 average rating, 215 reviews

Vicolo Fiore Affittacamere - BARISANO Room

VICOLO FIORE AFFITTACERE is strategically located for visiting the Sassi of Matera and at the same time being able to park freely along the streets. Located immediately inside the Historic Center, it will be the ideal property for you. We have 4 rooms but this listing is for the BARISANO Room, a Deluxe Double with terrace * BREAKFAST (served at the affiliated Bar) * PARKING (free on the street) * RECEPTION (from 11:00 a.m. or Self Check-In) * LUGGAGE DROP-OFF (free)

Top guest favorite

A spacious bedroom features a large bed framed by a metallic canopy. Soft bedding is complemented by light from two rounded bedside lamps. A wide stone wall is accented by an artwork and a minimalist shelf, while woven chairs and a striped bench add warmth to the space.

Hotel room in Ostuni

5 out of 5 average rating, 43 reviews

Masseria Paradiso B&B - Junior Suite 1

B&B in a 17th-century Masseria, surrounded by 8,500 mq of centuries-old olive groves, just 20 minutes from the beaches of Ostuni. 2 Junior Suites and 2 Suites with direct and independent access from the courtyard. Dazzling white walls, secluded courtyards, arches, stone details, and charming dry-stone walls. Breakfast with organic, locally sourced products: ancient grain bread baked, fruit from our historic orchard, and homemade cakes prepared daily by Patrizia.

Top guest favorite

A rustic dining area features a large wooden table surrounded by black metal chairs. Exposed stone walls and wooden beams add character to the space, while natural light enters through a window. The room is connected to a visible kitchen area, enhancing its communal feel.

Hotel room in Fiumefreddo Bruzio

4.95 out of 5 average rating, 128 reviews

The hospitable style of a seaside village in Calabria

The period residence offers numerous common areas: reading lounges, kitchen, breakfast room and terrace. The rooms are equipped with Wi-Fi, numerous balconies and windows overlooking the Tyrrhenian Sea. The beach is just 3 km from the ancient village. The "Vico Granatello" Residence offers the typical lifestyle of a village, made up of tranquility, conviviality, good and authentic things. Our motto is: "the beautiful, the good and the healthy".

Superhost

A well-appointed room features warm wooden flooring and elegant decor, with a spacious bed adorned with decorative pillows. A vibrant mural decorates one wall, and natural light enters through a large window, complemented by rich red drapes. A stylish chair and desk area are also visible.

Hotel room in Rome

4.81 out of 5 average rating, 2,829 reviews

38 Viminale Hill - Double Room 2

Our Guest House will allow you to visit the wonders of Rome on foot! Near Termini station, in front of the Opera House is the ideal location to spend a vacation in the Eternal City. Ultra-fast internet connection, emotional shower, chromotherapy, wet bar, 24 hours a day. The Colosseum, Trevi Fountain and Spanish Steps are a 15-minute walk away, and the Vatican is a 10-minute subway ride away. We look forward to seeing you!

A spacious bedroom is featured, showcasing a large bed with a neutral-toned bedspread and two white towels neatly arranged on top. Natural light fills the room from the open sliding door, which provides a view of the sea and a small balcony.

Hotel room in Polignano a Mare

4.83 out of 5 average rating, 12 reviews

Terra | 2-Bedroom Suite Seaview

Terra is a stylish, newly renovated apartment located on Via Sirene 199, right by the sea in Polignano a Mare. It features two comfortable bedrooms, one bathroom, and a fully equipped shared kitchen and livi. A small balcony adds a cozy outdoor touch. Ideally located close to the historic center with nearby parking available, it’s perfect for families or friends looking to enjoy Polignano with ease and comfort.

Top guest favorite

A balcony is presented with white, woven chairs and a small table, adorned with potted flowers. The expansive view showcases the deep blue sea meeting a clear sky, enhancing a serene outdoor atmosphere.

Hotel room in Positano

4.94 out of 5 average rating, 290 reviews

Casa Guadagno – Positano, Amalfi Coast

In this listing there are photos of multiple rooms, one of which will be assigned to you, based on availability at the property. Casa Guadagno is a family business founded in 1957 by Antonio Guadagno. Today, as back then, guests can feel at home in a pleasant and familiar environment, spending a relaxing vacation in a setting that only few places in the world can offer.

Guest favorite

A spacious sleeping area features a large bed dressed in crisp white linens. Soft lighting emanates from mounted sconces on either side. Neatly rolled towels are arranged on the bed. Light curtains frame a window, allowing natural light to gently illuminate the room.

Hotel room in Lecce

4.76 out of 5 average rating, 207 reviews

Palazzo Caminanti room3

Spaziosa camera matrimoniale o tripla in antica dimora situata in una tranquilla zona del centro storico leccese. Ottima per chi vuole conoscere e visitare la città e come punto di partenza per esplorare la penisola salentina. Camera matrimoniale o tripla su richiesta . Caminanti nasce dall 'idea di due amici di costruire un luogo preposto a un'accoglienza familiare

Top guest favorite

A modern bedroom features a spacious bed adorned with a light blue blanket. Natural light streams through the window, which is dressed with soft blue curtains. A sleek desk and chair are positioned nearby, complemented by a decorative flower arrangement.

Hotel room in Sorrento

4.96 out of 5 average rating, 227 reviews

Boutique Hotel Sorrento Historical Centre

Stylish furnished room with an ensuite bathroom and a small balcony overlooking the pedestrian area of the city, in the heart of the historical centre of Sorrento, a few minutes walking from the "Sorrento Lift". The ideal option for a romantic weekend with your partner, holidays with the family, an adventure with your best friends.