Vacation rentals in Santee

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Top-rated vacation rentals in Santee

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Guest favorite
A scenic view from the patio showcases the expansive river basin and surrounding landscape. Tall grass and vibrant flowers line the shore, while a large table with several chairs is positioned on the covered porch, ideal for outdoor dining and relaxation.
Cabin in Springfield
4.92 out of 5 average rating, 52 reviews

Overlooking Lewis and Clark Lake/Missouri River

You have no need to rough it to get to the best hunting, fishing and Naturalist area within hundreds of miles. The house has an unmatched view of the river basin, professional kitchen with a bar, fireplace, hot tub, two car garage and a sun-room with a lift up glass garage door to the covered porch. It sits less than a mile above Springfield State Park which boasts two boat ramps and a fish cleaning station. Come and stay–all you need is your groceries, toiletries and gear . 5 Star VRBO Rating

Guest favorite
A dining area features a wooden table set for four, complemented by dark wooden chairs. Natural light streams through a nearby window, creating patterns on the floor. The space includes a kitchen area with cabinets and an oven visible in the background.
Guesthouse in Yankton
4.89 out of 5 average rating, 53 reviews

Modern Guest Suite with Stunning Lake Views

Experience breathtaking views of Lewis and Clark Lake from your private, designer guest suite. Perched above the water and only 10 minutes from downtown Yankton, this is the ultimate sanctuary for couples or solo travelers seeking peace without sacrificing proximity. * Incredible lake views and abundant wildlife (deer/turkey) right outside your window *Fitted with unique touches and a plush Queen bed * Secluded country feel on a quiet county road, and minutes from the Marina and State Parks

Top guest favorite
The interior space features rustic wooden walls adorned with various signs and decorations. A staircase leads to an upper area, while a vintage truck is parked nearby. An American flag is displayed prominently in the background.
Farm stay in Randolph
4.97 out of 5 average rating, 178 reviews

T&T Rustic Loft!

Country living at it’s best! Located 6 miles from Randolph , Ne. Quite , peaceful country style of living! Have a small pond on site for your viewing pleasure and relaxing times with a full swing set for the young at heart fun times! My shed is heated during the winter months! FYI The Loft bedroom and TV room are located upstairs from the kitchen (Please bring your own food for meals! ) and bathroom are on the bottom floor! Recently add washer and dryer system! New central Air conditioning !

Top guest favorite
The split-level home is set against a backdrop of greenery, featuring a stone chimney and an American flag. An attached garage is visible alongside the well-maintained gravel driveway. Nearby, a large barn adds to the rural landscape, creating a calm and serene environment.
Home in Wakonda
4.98 out of 5 average rating, 211 reviews

Quiet split level farm home w/ garage parking

Welcome to the Gregoire Farm. Our home is a recently remodeled split level located on our family farm. It has 3 bedrooms and two baths as well a sofa bed. Park your car in our two car garage. Great place for a larger group to have plenty of room. A little ways off the beaten path but worth a little extra drive. 15 min drive to Vermillion, 20 min drive to Yankton and 35 minutes to Sioux Falls. If you are looking for a quiet place to yourself please consider us. Non-smoking, pet free home.

Top guest favorite
Cabin in Yankton
4.98 out of 5 average rating, 42 reviews

Secluded Ridgeway Hideout | Cozy, Porch, Fireplace

The Hideout on Ridgeway, a peaceful escape tucked away in nature yet close to everything you came for. 5 minutes to Gavin’s Boat Ramp on Lewis & Clark Lake, this spacious retreat is perfect for lake days, family gatherings and weekends with friends. Sip your coffee on the screened-in porch, cozy up by the fireplace, or settle in for movie night on the 75” TV in the loft. The home is fully stocked—linens, coffee, and cooking essentials are all provided—so you can arrive, unpack, and relax.

Superhost
Cabin in Verdigre
4.75 out of 5 average rating, 4 reviews

Deer Den Cabin - Your Cozy Nature Retreat

This cabin offers a breath of fresh air. Inside, you’ll find a rustic bedroom and a full bathroom stocked with all the essentials. The fully equipped kitchen lets you cook your favorite meals, while the cozy living and dining area—complete with a fold-out futon—provides extra space for guests or family. Roast marshmallows at the fire pit, grill on the barbecue and share a meal under the open sky. At sunrise, there’s no better spot than the patio watching deer wander through the morning mist.

Guest favorite
A charming white cabin with bright red accents is shown, featuring a welcoming entrance and a large window. Adjacent to the cabin is an outdoor patio with a grill and a pergola, surrounded by neatly trimmed greenery and trees.
Farm stay in Crofton
4.9 out of 5 average rating, 155 reviews

Delightful and Peaceful 1-Bedroom Farm Cabin

Get away from the busyness of life and relax in this peaceful farm cabin under the stars. The cabin features a full kitchen and dining area, along with access to an outdoor patio equipped with a grill, picnic table, and pergola. Inside, you’ll find a cozy living area with a loveseat and a 50” TV perfect for snuggling up and watching your favorite movie. The queen bed is located near the newly renovated bathroom, which includes a standing shower. Let us know if you’d like a tour of the farm!

Top guest favorite
A single-story cottage is set in a spacious yard, surrounded by trees. The exterior features light siding with dark trim and a welcoming front porch. The landscape is well-maintained, with patches of grass and decorative stones enhancing the natural setting.
Cottage in Springfield
4.98 out of 5 average rating, 42 reviews

River View Escape

Enjoy your stay with family or friends in this river view, peaceful cottage. If you’re lucky, you may catch a view of a Bald Eagle soaring down the river. Our place has a long driveway with plenty of room for trailers. The marina with a boat dock to the Missouri River is a short, few blocks away. There is an outside RV electrical hookup. The RV dump station is a few blocks away. Our family lived in this home for almost 10 years and now we are excited to share it with you!

Guest favorite
A spacious cabin with a prominent gabled roof is set against a clear sky. The exterior features pale yellow and dark maroon panels. A covered porch supported by wooden posts is visible, along with a well-maintained green lawn and decorative stone edging surrounding the area.
Cabin in Lake Andes
4.86 out of 5 average rating, 115 reviews

Sandollar Cove Cabin - Lake Fun, Fish, Pheasants!

3 floors of cabin feel comfort! Can sleep 10+! Close to North Point at Ft Randall Dam. Boat dock access less than 1/4 mile, campgrounds, beach, biking trails, pheasant hunting and fishing. Pickstown (population 220) about 5 miles. Wagner (pop 1600) about 18 miles. Lake Andes (pop 830) 7 miles. Please note charge for extra guests and we welcome your offers also! 7 beds, 2 pullout couches, 1 bathroom. Pheasant Country & Fishing Wonderland! Awesome friends in the neighborhood.

Top guest favorite
A light-filled living area showcases a comfortable sofa and a round wooden coffee table. The space transitions to a kitchen area with bar stools. Decorative mirrors and plants add a touch of style, while a ceiling fan enhances air circulation.
Home in Scotland
4.92 out of 5 average rating, 60 reviews

The Haven

25 minutes from Yankton and 6 minutes to the Lake Henry east of Scotland, SD. Scotland has a park, swimming pool, churches, grocery store, gas stations, coffee shop, thrift store. Kick back & relax in this clean, stylish Haven. Updated 2 bdrm, 1.5 bath home with new LVP flooring, paint, fixtures, updated baths, new breakfast bar, & coffee bar. Attached 1-car garage. Main floor laundry, deck & backyard. Quiet neighborhood. The unfinished basement has two beds if needed.

Top guest favorite
The exterior of the cabin duplex is shown, featuring a metal façade and a covered front porch. Large windows reflect the evening light, revealing a welcoming entrance. A flag is displayed in front, and a spacious gravel area is visible, along with adjacent garages.
Cabin in Niobrara
4.96 out of 5 average rating, 94 reviews

Kinsmen Lodge

Kinsmen lodge is located on the outskirts of Niobrara within view of the mighty Missouri River. We have a cabin duplex with each side a roomy 1000 square feet that can accommodate up to 6 guests. They have two bedrooms, private bath and full kitchen with a dining area and family room. Whether you are a group of friends or a family our cabin is built to serve your needs and is within walking distance of groceries, gas and restaurants.

Guest favorite
Cabin in Springfield
4.98 out of 5 average rating, 41 reviews

The Copper Lodge

River front property with plenty of parking! The copper lodge is located at 41059 main rd Springfield, SD 57062. The lodge consists of 900 sq ft living quarters with 1 King and 6- twin xl beds. A concrete patio for grilling and entertaining. There is a fire pit that guests are able to use. If you enjoy fishing, hunting, and boating, then you would be coming to the right place. The public boat dock is nearby.

Popular amenities for Santee vacation rentals

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  4. Knox County
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