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Vacation home rentals in Santa Cruz

Find and book unique vacation home rentals on Airbnb

Top-rated vacation home rentals in Santa Cruz

Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

A modern two-story building is set against a mountainous backdrop, featuring a combination of dark siding and natural stone accents. Large windows on both levels provide ample sunlight. Surrounding greenery includes tall pine trees and a neatly landscaped lawn.

Vacation home in El Chaltén

4.9 out of 5 average rating, 150 reviews

House 4, BUENAVISTA CHALTEN, MOUNTAIN HOUSES.

High-quality apartment. 2 bedrooms, fully equipped and 65 m2. Living room, dining room, and full kitchen with quality supplies and appliances (refrigerator, toaster, coffee maker, stove with oven, microwave, electric kettle, etc.) and 2 giant windows in the kitchen and living room with one of the best views of the village. Each bedroom has a sommier and quality linen, with the option of beds. 3 smart TVs, Wi-Fi, etc. Very good location, meters from the beginning of trails and close to downtown.

A close-up view of a wooden door with a sleek handle, featuring a keychain labeled 'DECO APARTS EL CALAFATE' hanging from the lock. Soft furniture in neutral tones is visible in the background, hinting at a welcoming living space.

Vacation home in El Calafate

4.91 out of 5 average rating, 55 reviews

Deco Aparts

Deco Aparts has fully equipped apartments for four people, with a kitchen with an oven and microwave, a living-dining room, and a bedroom with a double bed or two singles. Smart TV and Wi-Fi. We look forward to seeing you enjoy beautiful views of the lake and its sunsets. Just 15 meters from the main avenue, 100 meters from the bay and 1 kilometer from the center Live comfortably in our apartments. Our photos will show you all the details. The location is assigned based on availability.

Top guest favorite

The exterior of the house is shown, featuring a well-kept lawn with two turquoise chairs and a large umbrella. A wooden table is positioned at the center, and a bicycle is visible in the background. The house's light-colored walls and windows are clearly outlined.

Vacation home in El Chaltén

5 out of 5 average rating, 32 reviews

COIHUE HOUSE: Single-family home/Patio and Grill

Single-family home suitable for 4 people. It consists of an integrated kitchen, dining room and living room. Fully equipped with quality utensils and tableware. It has a double bedroom and a twin double bedroom. The armchair converts into two comfortable twin beds. Towels and bedding are provided. The bathroom has a shower and bathtub. A landscaped patio with vehicle access. Grill and/or barbecue. Outdoor night lighting system. We have Smart TV and WiFi.

A view of the coastal city from a large window reveals the blend of urban structures and the ocean in the background. Wooden decking and minimal furniture enhance the spaciousness, while soft vegetation frames the scene, inviting a calm connection with the outdoors.

Vacation home in Puerto Deseado

5 out of 5 average rating, 14 reviews

HOMU DEP – Vista al mar

Enjoy a luxurious stay. We are located at the top of Puerto Deseado, with excellent VIEWS OF THE CITY AND THE SEA. Minimalist in style, fully furnished and equipped, with everything you need for a pleasant stay. The duplex is 74 square meters, distributed over two levels: Ground floor: Living room with sofa, kitchen/dining room with exit to deck. Top floor: Master bedroom with queen size bed frame, another bedroom with two twin bed frames and a bathroom.

Top guest favorite

Vacation home in El Chaltén

4.94 out of 5 average rating, 88 reviews

Spacious and Cozy Apartment with the Best Location

🏠Beautiful apartment in El Chaltén, spacious, bright, and excellently located📍Accommodates up to 3 guests. Fully equipped to ensure you enjoy your stay. It includes a refrigerator, stovetop, microwave, electric kettle, and all the necessary utensils for cooking. In the neighborhood, you'll find cafés, restaurants, grocery stores, ice cream shop, stores to rent or buy trekking clothing and equipment ❇️We have a locker to store your luggage!

A modern dining area is presented with a light wooden table surrounded by four upholstered chairs. A sleek mirror and kitchen appliances, including a refrigerator and microwave, are visible against a neutral wall. Decorative elements such as a yellow centerpiece add a touch of warmth.

Vacation home in Caleta Olivia

4.77 out of 5 average rating, 60 reviews

Modern and Quiet Central Apartment

Enjoy a home in the heart of the city. A modern apartment, new, to rest and spend a few days, super comfortable in a bright and comfortable space It has a beautiful patio with grill, utensils and cutlery for 4 people. It also has a kitchen, a microwave, A/C, and a refrigerator. The location is excellent 200mtrs from the central street and main square. 200mtrs from a supermarket.

Top guest favorite

A modern building featuring a clean, contemporary design is set against a clear blue sky. Bright yellow flowers in the foreground add a touch of nature, complementing the architecture.

Vacation home in El Chaltén

4.93 out of 5 average rating, 76 reviews

Confluencia Aparts - P Ground Floor

The apartment is independent and fully equipped for a comfortable and relaxing stay. 600 meters from the Bus Terminal and the National Park's trailheads. The facilities have 1 double bed and 3 single beds, ideal for 5 people. Heating, private bathroom, fully-equipped kitchen.

Vacation rentals for every style

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Apartments

Convenient locations with everyday essentials

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Unique stays

Spaces that are more than just a place to sleep

Popular amenities for Santa Cruz vacation home rentals

Free parking on premises

Air conditioning

Family-friendly vacation home rentals

Two modern buildings are shown, featuring clean lines and a light green exterior. Large windows allow natural light to enter, while the surrounding landscape includes mountains in the background. A wooden fence runs along the property, enhancing the outdoor space.

Vacation home in El Chaltén

4.94 out of 5 average rating, 154 reviews

Otto's House, El Chaltén - Apartment 1

A view of the coastal city from a large window reveals the blend of urban structures and the ocean in the background. Wooden decking and minimal furniture enhance the spaciousness, while soft vegetation frames the scene, inviting a calm connection with the outdoors.

Vacation home in Puerto Deseado

5 out of 5 average rating, 14 reviews

HOMU DEP – Vista al mar

Top guest favorite

A modern structure is set against a backdrop of rolling hills, featuring unique stone accents and multiple windows. The building's design harmonizes with the natural landscape, with tall grass and sparse vegetation surrounding the property.

Vacation home in El Calafate

4.91 out of 5 average rating, 139 reviews

A peaceful place in the Patagonian steppe

A close-up view of a wooden door with a sleek handle, featuring a keychain labeled 'DECO APARTS EL CALAFATE' hanging from the lock. Soft furniture in neutral tones is visible in the background, hinting at a welcoming living space.

Vacation home in El Calafate

4.91 out of 5 average rating, 55 reviews

Deco Aparts

Top guest favorite

Vacation home in El Chaltén

4.94 out of 5 average rating, 88 reviews

Spacious and Cozy Apartment with the Best Location

A welcoming entrance is presented with a wooden door and framed by a well-kept garden. Lush green grass and various shrubs surround the front, while a small seating area is visible in the background, providing a relaxing outdoor space.

Vacation home in Los Antiguos

4.92 out of 5 average rating, 84 reviews

Apartment per day Route 41

A modern dining area is presented with a light wooden table surrounded by four upholstered chairs. A sleek mirror and kitchen appliances, including a refrigerator and microwave, are visible against a neutral wall. Decorative elements such as a yellow centerpiece add a touch of warmth.

Vacation home in Caleta Olivia

4.77 out of 5 average rating, 60 reviews

Modern and Quiet Central Apartment

Top guest favorite

Two modern buildings are set against a backdrop of mountain peaks. One building features large windows, allowing natural light to enter, while the other has a sloped roof. A wooden fence marks the boundary, enhancing the outdoor space.

Vacation home in El Chaltén

4.98 out of 5 average rating, 166 reviews

Otto's House, El Chaltén - Apartment 2

Vacation home rentals with a patio

Two modern buildings are shown, featuring clean lines and a light green exterior. Large windows allow natural light to enter, while the surrounding landscape includes mountains in the background. A wooden fence runs along the property, enhancing the outdoor space.

Vacation home in El Chaltén

4.94 out of 5 average rating, 154 reviews

Otto's House, El Chaltén - Apartment 1

A bright blue exterior of a single-story house is visible, complemented by white trim around the windows and door. Gravel surrounds the house, and a wooden seating area is located in the background. The sky is partly cloudy, adding a serene touch to the setting.

Vacation home in El Calafate

4.85 out of 5 average rating, 20 reviews

A spacious and comfortable apartment!!!!

A wooden cabin is positioned on a spacious lot, with a metal roof and multiple windows overlooking the ocean. The surrounding area features a sandy landscape under a clear blue sky, providing a serene atmosphere. The cabin's exterior showcases a warm, rustic charm.

Vacation home in Caleta Olivia

4.86 out of 5 average rating, 7 reviews

A CABIN IN FRONT OF THE SEA... NEAR THE SEA LIONS

A charming, single-story building is displayed, featuring large windows that allow natural light in. A small patio area is visible with wooden furniture arranged casually. The surrounding green lawn and distant glimpses of the lake create a sense of openness and tranquility.

Vacation home in El Calafate

5 out of 5 average rating, 7 reviews

Patagonian Cielos Aparts, the peace you want

A spacious bedroom features a double bed with decorative orange pillows and neatly arranged towels. Side tables with modern lamps are positioned on either side of the bed. Natural light filters in through two windows, creating a warm and welcoming ambiance.

Vacation home in El Calafate

4.4 out of 5 average rating, 15 reviews

Sher Apart Central located

Top guest favorite

The modern room features wooden accents and a sloped ceiling. A spacious bed is adorned with colorful pillows. A wall-mounted television and wooden shelf add functionality, while large windows allow natural light to brighten the space, offering a view of the surrounding garden.

Vacation home in El Chaltén

4.99 out of 5 average rating, 98 reviews

Loft, garden, and parking

A sleeping area features a spacious bed with a navy blue coverlet and two light blue pillows. Shelves are mounted on either side of the bed, each with a white lamp. A vibrant red wall is complemented by a framed landscape photograph above the bed, while natural light enters through a nearby window.

Vacation home in El Chaltén

4.81 out of 5 average rating, 37 reviews

Polo Aparts 3

A light-colored living area features a comfortable gray sofa with textured cushions, positioned against a lavender wall. Light fixtures above provide illumination. A wooden sliding barn door complements the space, while a dining table and kitchen appliances are visible in the background.

Vacation home in El Chaltén

4.86 out of 5 average rating, 37 reviews

Polo Aparts apartment for two people

Other vacation home rentals

Two modern buildings are shown, featuring clean lines and a light green exterior. Large windows allow natural light to enter, while the surrounding landscape includes mountains in the background. A wooden fence runs along the property, enhancing the outdoor space.

Vacation home in El Chaltén

4.94 out of 5 average rating, 154 reviews

Otto's House, El Chaltén - Apartment 1

A view of the coastal city from a large window reveals the blend of urban structures and the ocean in the background. Wooden decking and minimal furniture enhance the spaciousness, while soft vegetation frames the scene, inviting a calm connection with the outdoors.

Vacation home in Puerto Deseado

5 out of 5 average rating, 14 reviews

HOMU DEP – Vista al mar

Top guest favorite

A modern structure is set against a backdrop of rolling hills, featuring unique stone accents and multiple windows. The building's design harmonizes with the natural landscape, with tall grass and sparse vegetation surrounding the property.

Vacation home in El Calafate

4.91 out of 5 average rating, 139 reviews

A peaceful place in the Patagonian steppe

A close-up view of a wooden door with a sleek handle, featuring a keychain labeled 'DECO APARTS EL CALAFATE' hanging from the lock. Soft furniture in neutral tones is visible in the background, hinting at a welcoming living space.

Vacation home in El Calafate

4.91 out of 5 average rating, 55 reviews

Deco Aparts

A welcoming entrance is presented with a wooden door and framed by a well-kept garden. Lush green grass and various shrubs surround the front, while a small seating area is visible in the background, providing a relaxing outdoor space.

Vacation home in Los Antiguos

4.92 out of 5 average rating, 84 reviews

Apartment per day Route 41

A modern dining area is presented with a light wooden table surrounded by four upholstered chairs. A sleek mirror and kitchen appliances, including a refrigerator and microwave, are visible against a neutral wall. Decorative elements such as a yellow centerpiece add a touch of warmth.

Vacation home in Caleta Olivia

4.77 out of 5 average rating, 60 reviews

Modern and Quiet Central Apartment

Top guest favorite

Vacation home in El Chaltén

4.94 out of 5 average rating, 88 reviews

Spacious and Cozy Apartment with the Best Location

Top guest favorite

Two modern buildings are set against a backdrop of mountain peaks. One building features large windows, allowing natural light to enter, while the other has a sloped roof. A wooden fence marks the boundary, enhancing the outdoor space.

Vacation home in El Chaltén

4.98 out of 5 average rating, 166 reviews

Otto's House, El Chaltén - Apartment 2