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Vacation home rentals in Santa Cruz

Find and book unique vacation home rentals on Airbnb

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Vacation rentals for every style

Get the amount of space that is right for you

Popular amenities for Santa Cruz vacation home rentals

Kitchen
Wifi
Pool
Free parking on premises
Air conditioning

Family-friendly vacation home rentals

Guest favorite
Two modern buildings are shown, featuring clean lines and a light green exterior. Large windows allow natural light to enter, while the surrounding landscape includes mountains in the background. A wooden fence runs along the property, enhancing the outdoor space.
Vacation home in El Chaltén
4.94 out of 5 average rating, 154 reviews

Otto's House, El Chaltén - Apart 1

Guest favorite
A view of the coastal city from a large window reveals the blend of urban structures and the ocean in the background. Wooden decking and minimal furniture enhance the spaciousness, while soft vegetation frames the scene, inviting a calm connection with the outdoors.
Vacation home in Puerto Deseado
5 out of 5 average rating, 14 reviews

HOMU DEP - Vista al mar

Top guest favorite
A modern structure is set against a backdrop of rolling hills, featuring unique stone accents and multiple windows. The building's design harmonizes with the natural landscape, with tall grass and sparse vegetation surrounding the property.
Vacation home in El Calafate
4.91 out of 5 average rating, 139 reviews

Lugar de paz en la estepa patagónica

Guest favorite
A close-up view of a wooden door with a sleek handle, featuring a keychain labeled 'DECO APARTS EL CALAFATE' hanging from the lock. Soft furniture in neutral tones is visible in the background, hinting at a welcoming living space.
Vacation home in El Calafate
4.91 out of 5 average rating, 55 reviews

Deco Aparts

Top guest favorite
Vacation home in El Chaltén
4.94 out of 5 average rating, 88 reviews

Spacious and Cozy Apartment with the Best Location

Guest favorite
A welcoming entrance is presented with a wooden door and framed by a well-kept garden. Lush green grass and various shrubs surround the front, while a small seating area is visible in the background, providing a relaxing outdoor space.
Vacation home in Los Antiguos
4.92 out of 5 average rating, 84 reviews

Departamento por día ruta41

Guest favorite
A modern dining area is presented with a light wooden table surrounded by four upholstered chairs. A sleek mirror and kitchen appliances, including a refrigerator and microwave, are visible against a neutral wall. Decorative elements such as a yellow centerpiece add a touch of warmth.
Vacation home in Caleta Olivia
4.77 out of 5 average rating, 60 reviews

Apartamento Céntrico Moderno y Tranquilo

Top guest favorite
Two modern buildings are set against a backdrop of mountain peaks. One building features large windows, allowing natural light to enter, while the other has a sloped roof. A wooden fence marks the boundary, enhancing the outdoor space.
Vacation home in El Chaltén
4.98 out of 5 average rating, 166 reviews

Otto's House, El Chaltén - Apartment 2

Vacation home rentals with a patio

Guest favorite
Two modern buildings are shown, featuring clean lines and a light green exterior. Large windows allow natural light to enter, while the surrounding landscape includes mountains in the background. A wooden fence runs along the property, enhancing the outdoor space.
Vacation home in El Chaltén
4.94 out of 5 average rating, 154 reviews

Otto's House, El Chaltén - Apart 1

A bright blue exterior of a single-story house is visible, complemented by white trim around the windows and door. Gravel surrounds the house, and a wooden seating area is located in the background. The sky is partly cloudy, adding a serene touch to the setting.
Vacation home in El Calafate
4.85 out of 5 average rating, 20 reviews

Departamento amplio y cómodo!!!!

A wooden cabin is positioned on a spacious lot, with a metal roof and multiple windows overlooking the ocean. The surrounding area features a sandy landscape under a clear blue sky, providing a serene atmosphere. The cabin's exterior showcases a warm, rustic charm.
Vacation home in Caleta Olivia
4.86 out of 5 average rating, 7 reviews

CABAÑA FRENTE AL MAR...CERCA DE LOS LOBOS MARINOS

A charming, single-story building is displayed, featuring large windows that allow natural light in. A small patio area is visible with wooden furniture arranged casually. The surrounding green lawn and distant glimpses of the lake create a sense of openness and tranquility.
Vacation home in El Calafate
5 out of 5 average rating, 7 reviews

Cielos Patagónicos Aparts, la paz que deseas

A spacious bedroom features a double bed with decorative orange pillows and neatly arranged towels. Side tables with modern lamps are positioned on either side of the bed. Natural light filters in through two windows, creating a warm and welcoming ambiance.
Vacation home in El Calafate
4.4 out of 5 average rating, 15 reviews

Sher Apart Central located

Top guest favorite
The modern room features wooden accents and a sloped ceiling. A spacious bed is adorned with colorful pillows. A wall-mounted television and wooden shelf add functionality, while large windows allow natural light to brighten the space, offering a view of the surrounding garden.
Vacation home in El Chaltén
4.99 out of 5 average rating, 98 reviews

Loft, jardín y estacionamiento

Guest favorite
A sleeping area features a spacious bed with a navy blue coverlet and two light blue pillows. Shelves are mounted on either side of the bed, each with a white lamp. A vibrant red wall is complemented by a framed landscape photograph above the bed, while natural light enters through a nearby window.
Vacation home in El Chaltén
4.81 out of 5 average rating, 37 reviews

Polo Aparts 3

Superhost
A light-colored living area features a comfortable gray sofa with textured cushions, positioned against a lavender wall. Light fixtures above provide illumination. A wooden sliding barn door complements the space, while a dining table and kitchen appliances are visible in the background.
Vacation home in El Chaltén
4.86 out of 5 average rating, 37 reviews

Polo Aparts dpto para dos personas

Other vacation home rentals

Guest favorite
Two modern buildings are shown, featuring clean lines and a light green exterior. Large windows allow natural light to enter, while the surrounding landscape includes mountains in the background. A wooden fence runs along the property, enhancing the outdoor space.
Vacation home in El Chaltén
4.94 out of 5 average rating, 154 reviews

Otto's House, El Chaltén - Apart 1

Guest favorite
A view of the coastal city from a large window reveals the blend of urban structures and the ocean in the background. Wooden decking and minimal furniture enhance the spaciousness, while soft vegetation frames the scene, inviting a calm connection with the outdoors.
Vacation home in Puerto Deseado
5 out of 5 average rating, 14 reviews

HOMU DEP - Vista al mar

Top guest favorite
A modern structure is set against a backdrop of rolling hills, featuring unique stone accents and multiple windows. The building's design harmonizes with the natural landscape, with tall grass and sparse vegetation surrounding the property.
Vacation home in El Calafate
4.91 out of 5 average rating, 139 reviews

Lugar de paz en la estepa patagónica

Guest favorite
A close-up view of a wooden door with a sleek handle, featuring a keychain labeled 'DECO APARTS EL CALAFATE' hanging from the lock. Soft furniture in neutral tones is visible in the background, hinting at a welcoming living space.
Vacation home in El Calafate
4.91 out of 5 average rating, 55 reviews

Deco Aparts

Guest favorite
A welcoming entrance is presented with a wooden door and framed by a well-kept garden. Lush green grass and various shrubs surround the front, while a small seating area is visible in the background, providing a relaxing outdoor space.
Vacation home in Los Antiguos
4.92 out of 5 average rating, 84 reviews

Departamento por día ruta41

Guest favorite
A modern dining area is presented with a light wooden table surrounded by four upholstered chairs. A sleek mirror and kitchen appliances, including a refrigerator and microwave, are visible against a neutral wall. Decorative elements such as a yellow centerpiece add a touch of warmth.
Vacation home in Caleta Olivia
4.77 out of 5 average rating, 60 reviews

Apartamento Céntrico Moderno y Tranquilo

Top guest favorite
Vacation home in El Chaltén
4.94 out of 5 average rating, 88 reviews

Spacious and Cozy Apartment with the Best Location

Top guest favorite
Two modern buildings are set against a backdrop of mountain peaks. One building features large windows, allowing natural light to enter, while the other has a sloped roof. A wooden fence marks the boundary, enhancing the outdoor space.
Vacation home in El Chaltén
4.98 out of 5 average rating, 166 reviews

Otto's House, El Chaltén - Apartment 2