
Vacation rentals in Santa Cruz
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Santa Cruz
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Cruz vacation rentals
Other great vacation rentals in Santa Cruz
Top guest favorite

Shipping container in San Carlos
5 out of 5 average rating, 31 reviewsJustinatinyhouse desconecta para conectar
Superhost

Cottage in Chame District
4.8 out of 5 average rating, 60 reviewsCasa de campo con piscina en montañas de Panamá
Guest favorite

Condo in Coronado
5 out of 5 average rating, 10 reviewsCoronado bay on the beach with large terrace
Top guest favorite

Condo in Nueva Gorgona
4.93 out of 5 average rating, 44 reviewsCondo in front of the beach with Mountain View
Superhost

Villa in Chame District
5 out of 5 average rating, 4 reviewsCasa de playa con piscina y jacuzzi
Guest favorite

Home in Coloncito
4.84 out of 5 average rating, 51 reviewsHermosa villa de playa
Superhost

Home in Nueva Gorgona
4.89 out of 5 average rating, 36 reviewsCasa de las Palmas
Guest favorite

Apartment in Coronado
4.94 out of 5 average rating, 18 reviewsPetit appartement Piscine Golf
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