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Vacation rentals in Santa Cruz

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Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A bright bedroom features a spacious bed layered with soft linens and a cozy throw blanket. Decorative wall art complements the modern design. A bedside lamp adds a warm touch, while large windows offer scenic views of the ocean and natural light filling the room.
Apartment in Nueva Gorgona
4.89 out of 5 average rating, 102 reviews

Cozy Beachfront Apartment

This small and cozy apartment is the perfect place to call home. Located just steps away from the beach with its charming and homey atmosphere. The large windows allow natural light to flood the space. It has everything you need in a compact and convenient space. The living room is warm and inviting. The kitchen is fully equipped with modern appliances, making it easy to prepare meals at home. The bedroom is spacious and bright, with a comfortable bed and plenty of storage for your belongings.

Guest favorite
An expansive view of a tranquil beach is seen, with soft sandy shores meeting clear turquoise waters. The horizon features a blend of blue sky and distant buildings, while palm trees and shaded cabanas dot the beach area.
Condo in Chame District
4.96 out of 5 average rating, 166 reviews

Exclusive Beachfront apartment 1Hour from Pma City

ESPECTACULAR apartamento de lujo FULL EQUIPADO con 3 recamaras (todas con vista directa al mar), 2 baños completos y medio baño de visita; cuarto y baño de servicio. Finos acabados, cocina 100% de acero inoxidable y aires acondicionados en todo el apartamento de alta eficiencia. Condominio con concepto "Hotel Style Living"; Restaurante y Bar para las noches (de Jueves a Domingo), snack bar en el area de la piscina y un Tiki Bar en la playa, ademas de cancha de Volleyball , Tenis, basketball.

Superhost
The outdoor area features a swimming pool with sun loungers arranged around it. Umbrellas provide shade, and the surrounding greenery enhances the space. In the background, the ocean and sky create a scenic backdrop, with the villa positioned to the left.
Villa in Chame
4.83 out of 5 average rating, 113 reviews

Ocean Pergola Villa (C10-PBB) 2 bed, 2 bath

Unique place steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space and an outside pergola area. (4 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views. Playa Caracol is located on the beach of Chame and is a newly developed area with expansion for the property and amenities. 1km of beach to offer you the best beach experience around.

Top guest favorite
An aerial view of the property showcases a spacious layout surrounded by lush greenery. A large saltwater pool and a hot tub are visible alongside a well-maintained outdoor area with red umbrellas providing shade. The roof of the main structure features a brown tone, blending with the natural surroundings.
Home in Costa Esmeralda
4.98 out of 5 average rating, 179 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with solar and battery backup systems.

Superhost
An aerial view reveals a stretch of coastline featuring sandy beaches with a mix of dark volcanic sand and vibrant turquoise water. Lush greenery lines the shore, complemented by residential areas visible in the background, creating a serene and inviting landscape.
Tiny home in San Carlos
4.8 out of 5 average rating, 123 reviews

Cozy beach cabin at Costa Esmeralda.

Cozy private community cabin on a triple space for up to three people located in Costa Esmeralda beach, over the Pacific ocean. Very quiet area with a 2,200 Square meter patio with trees and vegetation. Relax enjoying of the tropical sun, warm temperatures all year long and the ocean breeze. Only 8 minutes away by walk from the closest beach with warm waters and volcanic black sand. 10 minute drive to Coronado (Grocery Stores, restaurants, bakeries, movie theater, malls and more)...

Top guest favorite
The exterior of the house features a charming design with a red-roofed upper level and a welcoming terrace. A small pool is visible in the foreground, surrounded by lush greenery and natural rock formations. Cloudy skies create a serene atmosphere, enhancing the tranquil setting.
Home in El Nancito
4.95 out of 5 average rating, 19 reviews

Mountain Retreat: Peaceful & Private Escape

Escape to tranquility in our beautiful rural retreat near Laguna de San Carlos, Panama. Nestled on a private hectare of lush land, this cozy two-bedroom, two-bath house boasts an open terrace with breathtaking views of the San Carlos mountains. Whether basking in summer sun or enveloped in clouds during the rainy season, you’ll find peace and beauty here. Just a 30-minute drive to Coronado and the stunning beaches of Panama Oeste, it’s the perfect sanctuary for your getaway.

Guest favorite
A stone paved area features four wooden chairs arranged around a central fire pit, illuminated by soft landscape lighting. In the background, a cabin structure can be seen, bordered by lush greenery and softly lit paths, creating an inviting outdoor space.
Cabin in Provincia de Panamá Oeste
4.88 out of 5 average rating, 256 reviews

Buenavista Cabin by Casa Amaya

Casa Amaya is a cabin complex located one hour from the capital city, in Chicá de Chame, with pleasant temperatures between 18 and 24 degrees, where you can get in touch with nature and relax with your partner, friends or family. Other cabins: https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/panoramabycasaamaya https://www.airbnb.com/h/horizontebycasaamaya We have an electric generator in case of outages.

Guest favorite
A balcony with a panoramic view of the coastline and turquoise waters is furnished with two cozy chairs and a small table. A long wooden bar table stands nearby, offering additional seating. The bright blue sky complements the scenic landscape.
Apartment in Nueva Gorgona
4.88 out of 5 average rating, 57 reviews

Beachfront apartment on the 15th floor

Relax with the whole family at this peaceful place to stay. The building has 4 swimming pools, 1 Jacuzzi, 1 sauna, gym, volleyball court, futsal, pickleball or mini tennis, gazebos, a restaurant and BBQ area. The latter is rented for an additional $25. The apartment has 2 bedrooms, a living room, a breakfast area, a full white line with a dishwasher, a laundry center, 3 air conditioners, a hair dryer, an iron, and a balcony. 1 queen bed and a bunk bed.

Guest favorite
Condo in Nueva Gorgona
5 out of 5 average rating, 5 reviews

Gorgeous Beachfront High Floor

Oceanfront escape! Bright 2BR/2BA condo with floor-to-ceiling windows, modern kitchen, and private balcony overlooking the turquoise sea. Relax in the spacious living area, enjoy stunning sunsets, or unwind in the stylish bedrooms with en-suite baths. Perfect for couples, families, or remote work with breathtaking views. Steps from the beach, dining & entertainment. Your dream coastal getaway awaits!

Guest favorite
Cabin in Provincia de Panamá Oeste
4.88 out of 5 average rating, 42 reviews

Cabin surrounded by mountains with spectacular views

Our cabin combines comfort, style and privacy, surrounded by mountains, forest and fresh air. Great for couples or families looking to disconnect and recharge. ✔ Price is up to four people. Additional $25 each. ✔ Zip line, climbing wall, karaoke. lake 15 minutes away. Fresh ✔ weather year-round. Enjoy the experience of resting in a place designed for you, close to and far from everything.

Guest favorite
A spacious outdoor area is visible, featuring a tiled-roof gazebo with seating and a hammock. Lush greenery surrounds the space, including well-maintained grass and flowering bushes. A nearby building is partially seen, blending organically with the natural environment.
Home in chame
4.86 out of 5 average rating, 14 reviews

cozy corner with pool minutes away from the beach

a minutos de coronado las playas rios supermercados restaurantes y mas. se renta por dia semanal anual o mensual. se renta caballos. al igual si quiere ordenar comida nos deja saber para tenerselo listo. o si necesita alquien que le limpia, lave o cambie las camas a precio especial tambien se le puede adicionar. puede traer sus mascotas.

Guest favorite
The two-story house is illuminated at night, showcasing vibrant exterior colors and a balcony on the upper floor. Large windows are visible, allowing light to spill out. A seating area is set up in the outdoor space, surrounded by plants and decorative string lights.
Home in El Valle de Antón
4.81 out of 5 average rating, 257 reviews

Casa Antares by Esther

Agradable casa de dos pisos con vistas a las montañas. **NO APTO PARA PERSONAS CON POCA MOVILIDAD, FAVOR LEER SECCIÓN DE SEGURIDAD** Dos cuartos privados en la parte superior con balcón en la habitación principal. Baño, sala y cocina en la planta baja. Contamos con bicicletas para que puedan pasear alrededor del Valle de Antón.

Popular amenities for Santa Cruz vacation rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz