Guesthouse vacation rentals in Santa Clarita

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Santa Clarita

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

A tranquil evening scene by the pool features illuminated water in shades of blue. A jacuzzi is situated nearby, while string lights create a warm ambiance overhead. Comfortable seating is arranged around the pool area, surrounded by lush greenery, providing a welcoming outdoor space.

Guesthouse in Newhall

4.98 out of 5 average rating, 495 reviews

Cozy Guesthouse with Private Pool + Heated Jacuzzi

✅ Prime Location: 12 min to Magic Mountain, 30 min to Universal Studios, 45 min to the beach. Close to dining and shopping. *Private guesthouse with its own entrance, fully fenced for your peace and privacy. *Relax with a private pool (not heated), a large heated spa, and a Blackstone griddle for outdoor cooking. *Master bedroom + open loft (as a second bedroom), kitchenette (no oven), living room, WiFi, washer/dryer. *Dedicated parking. Max 8 guests (contact us for exceptions). No parties.

Guest favorite

The outdoor area features a sparkling pool surrounded by lush greenery, with light reflections enhancing the water's surface. A shaded table with chairs is positioned nearby, under a large umbrella. Soft lighting adorns the palm trees, creating a welcoming atmosphere for relaxation.

Guesthouse in Granada Hills

4.95 out of 5 average rating, 136 reviews

Bella's Suite is a cozy, quiet, poolside getaway.

Bella's suite feels like a tropical getaway with its soothing earth tone décor. You immediately feel like you are home. There's a full kitchen, a beautiful rain shower, a very comfortable memory foam queen bed, 2 Roku TVs, a dining table, and a dedicated workspace in the bedroom. You can relax by the pool located next to the suite. Both inside & outside of Bella's Suite are supremely well-kept and cleaned after each stay. It is blocks away from grocery stores, restaurants, and major freeways.

Guest favorite

The exterior of a spacious, two-story house is shown, featuring a light-colored facade and a terracotta tile roof. A landscaped front yard includes shrubs and decorative stones. A driveway leads to a garage, and the surrounding neighborhood gives a sense of tranquility.

Guesthouse in Santa Clarita

4.86 out of 5 average rating, 214 reviews

HILLSIDE GETAWAY next to Magic Mountain

Great reviews beautiful quiet neighborhood on top of hill with an amazing view of the surrounding mountains w/private entrance 15min drive to six flags magic mountain bike paths an nature trails shopping and malls less than 5 min drive everything newly built all guests have given me 5star accommodations easily sleeps 4 people fold out couch in living room queen size bed in bedroom room 16 ft high cathedral ceiling private balcony /tables&chairs purfect to unwind 30 min from universal studios

Top guest favorite

A cozy sleeping area features a spacious bed adorned with various pillows and a textured blanket. On either side of the bed, minimalist nightstands with lamps provide lighting. Three abstract artworks are displayed above the headboard, enhancing the serene ambiance.

Guesthouse in Simi Valley

4.92 out of 5 average rating, 163 reviews

Serene Studio | Modern Touches & Natural Light

Modern studio centrally located to everything the Simi Valley area has to offer. Just a few minutes from the freeway, shopping and restaurants. This recently renovated, private studio is fully equipped for your stay. A combination of modern and natural tones gives this studio a warm feeling of style and comfort. Just right for couples or solo travelers looking for a snug place to rest. Please note the studio is attached to the main home and a train passes nearby. Possible noise may be heard.

Top guest favorite

A cozy studio interior showcases a queen bed adorned with decorative pillows and a soft throw. A futon is positioned nearby, with a small table between them. Natural light fills the space, highlighting the calming color palette and inviting decor, along with a glimpse of the kitchen area.

Guesthouse in Sylmar

4.99 out of 5 average rating, 228 reviews

Tranquil Studio w/ private patio

A beautiful and well maintained Tranquil Studio/ With a Private Patio. Entire Studio to yourselves. 2 guests. 1 queen bed..1 queen/futon couch, with lovely bed linens and plush towels. 1 tub/shower.Futon made up on request at the time of booking. Full kitchen with everything you’d need to make delicious meals. 55” TV/ DVDs Washer/dryer...please bring your own laundry soap and dryer sheets. The gorgeous private patio has plenty of space to relax and enjoy your meals, or just hang out.

Top guest favorite

An open studio guest house features a plush queen bed framed by bedside lamps and a ceiling fan. A cozy sofa and recliner are situated beside a small retro refrigerator and a coffee station. A neutral area rug enhances the warmth of the wood flooring.

Guesthouse in Newhall

5 out of 5 average rating, 136 reviews

Hideaway Heaven $120 per night + 25.00 cleaning

Where movie magic happens nestled in the heart of Santa Clarita is a charming studio guest house thoughtfully designed with all the comforts of your own home including a soak in tub to enjoy and relax after a long day. Location is key, and this beautiful guest home is minutes from the 14 freeway,hiking trails , dining, Six Flags Magic Mountain, and film locations. This attached suite is newly renovated with all new furnishings, a private and separate entrance with a designated parking spot.

Guest favorite

The guest room features a spacious queen bed with white linens, complemented by decorative pillows. A large area rug adds color to the hardwood floor. Natural light enters through double doors leading to a private patio, with sheer curtains softly framing the entrance.

Guesthouse in Reseda

4.94 out of 5 average rating, 588 reviews

Private Guesthouse

This is a very comfortable NON-SMOKING guesthouse/ studio room with private entrance. Absolutely NO ANIMALS allowed due to my allergies. It has one queen bed. Private full bathroom. There is dresser space as well as hangers. It also has a desk for work space. Smart TV can be used with streaming services. This space does not have a kitchen. But it does have a small fridge and a microwave. Absolutely no filming or photography anywhere on the premises. No visitors allowed without my consent.

Guest favorite

A spacious guest suite features a California King size bed with decorative pillows, accompanied by a comfortable couch. A kitchenette area is visible, including a silver refrigerator and black appliances. Soft lighting from a wall-mounted design adds a cozy touch to the neutral-toned walls.

Guesthouse in Woodland Hills

4.97 out of 5 average rating, 640 reviews

Safe Guesthouse /K bd /near Topanga Cyn /Calabasas

Perfect getaway for anyone looking for a SAFE and CLEAN gated and secure sanctuary that is conveniently located near Warner Center, Westfield Topanga ,The Village, Topanga Canyon and the beach! STRONG WIFI PERFECT FOR WOMEN TRAVELING ALONE space us 484 sq ft (detached from front house) with KITCHENETTE (no stove or sink) including a Microwave, large Refrigerator with Freezer, Keurig with coffee/ Tea also plates, bowls, glasses, cups and Ice. 6 windows Air Cond/ Heating unit

Superhost

A bright and open kitchen area features modern appliances and a circular dining table surrounded by plush pink chairs. Large glass doors allow natural light to fill the space, while vibrant artwork adorns the walls, complementing the colorful decor.

Guesthouse in Burbank

4.92 out of 5 average rating, 183 reviews

Adorable 1bed Old Hollywood Inspired Guest House

Welcome to my old-Hollywood inspired home. This guest house sits on a large property with the main house. It's only fitting that an Old-Hollywood home would be right in the middle of the movie studio capital. Burbank is the home of big movie studios and a rich cultural society. Not too far from the party that is Hollywood, but tucked away enough for those who like the party to stop when it's bedtime. I’m so glad to share this space with you and I hope you enjoy it.

Top guest favorite

A cozy guest room is equipped with a spacious bed covered in a textured blanket. A sleek work desk and chair are visible, along with a television displaying a beach scene. Large glass doors lead to an outdoor patio area, and a potted plant adds a touch of greenery.

Guesthouse in Burbank

4.98 out of 5 average rating, 303 reviews

Private Guest Quarters with Patio & Bathroom

Enjoy a stylish experience at this centrally-located place in Burbank. Walking distance to Starbucks, minutes away from Disney Studios, Warner Bros. and Universal Studios. Conveniently located near the Hollywood Burbank Airport. Perfect for one-guest. Host lives on premises. Room has a private entrance with outdoor patio. There are two cameras located on the property, one on the Hosts front door, the second one attached to the Hosts home overlooking the backYard.

Top guest favorite

A green wooden exterior features a welcoming front door framed by two large windows. A small seating area includes a metal chair next to the entrance, and potted plants add a touch of greenery along the pathway leading up to the door.

Guesthouse in Lake Hughes

4.92 out of 5 average rating, 332 reviews

The Guesthouse at Hidden Acres

Beautiful, rustic, quiet country get-away. Just 90 minutes North of L.A. on the edge of Angeles National Forest. Perfect for an artist or writer's retreat. Private studio guesthouse on 17 acres. New mini split unit keeps the space comfortable year round. And the wood-burning stove is super cozy on cold nights. Includes fully stocked kitchen, sunken tub in bath, large writer's desk, and miles of hiking trails along the Pacific Crest Trail.

Top guest favorite

A spacious bedroom includes a large bed with a light coverlet, complemented by natural light from two windows dressed with soft curtains. A small wooden table and a woven basket provide additional decor, while greenery adds a fresh touch to the inviting space.

Guesthouse in Simi Valley

4.96 out of 5 average rating, 104 reviews

Rustic Ranch Retreat: Guesthouse with Nature Views

Escape to the tranquility of our picturesque working ranch, where you can experience the rustic charm of farm life like never before. Welcome to our one-of-a-kind Airbnb. Ranch Getaway: Unplug and unwind in our cozy guesthouse, nestled amidst the rolling hills of our working ranch. Here, you'll find a true escape from the hustle and bustle of city life, while only being one mile from the freeway. Parties are not allowed at The Ranch.