
Vacation rentals in San Pedro del Espino
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Top-rated vacation rentals in San Pedro del Espino
Guests agree: these stays are highly rated for location, cleanliness, and more.

Raices de Domingo Cabin
Experience authentic Panama in our family-owned 30-hectare private tropical beachfront paradise. Accessible only by boat (20-min ride from Pixvae or 1hr from Santa Catalina). Gateway to Coiba Island, our remote bay offers pristine jungle, diverse wildlife, and breathtaking views. Enjoy kayaking, fishing, and guided eco-tours. Spot howler monkeys, sloths, and rare birds. Savor fresh tropical fruits and local cuisine. Perfect for nature lovers, photographers, and digital nomads (WiFi available).

Casa de Campo in Olá, rivers, waterfalls, Los Picachos
Finca La Terapia honors its name, it is located among the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day to day of the city. It has 42 private hectares to explore nature. The Olá district is characterized by having the most beautiful natural landscapes among which we can mention, Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the Farm.

Santa Fe villa with a espectacular view
Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

k* Casa Matilde | 2BR Santa Fe Retreat by River
Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

Colonial House in Parita
Discover the charm of Parita from a comfortable and spacious home, perfect for large groups. Located in the picturesque and peaceful town of Parita, in the Herrera Province, just 12 minutes from Chitré, this spacious home is the ideal place to immerse yourself in the history and culture of a historic colonial-era town.

Serena Lodge & Camping - El Cope
Nestled in the heart of El Cope, Panama, Serena Lodge at Ventorrillo is surrounded by lush greenery, majestic mountains, and pristine rivers. Our secluded location provides a peaceful sanctuary away from the hustle and bustle of city life, offering guests a chance to reconnect with nature and rejuvenate their senses.

d'rosas apartamentos 3PB
Discover the comfort in our cozy home in the heart of Santiago, Veraguas. Just a 5 minute walk from downtown, you'll enjoy a well-equipped space that includes all the necessary amenities for a relaxing stay. Ideal for exploring local culture and resting after a day of adventure. We look forward to seeing you!

La Yeguada - Forest Point Cabin
It takes the whole family to this fantastic place with many areas to have fun, fully equipped cottage with spacious kitchen, living room with access to TV, hammocks, refrigerator, stove, hot water and everything you need to have a good time away from the noise and live with nature.

Cabin with river view
Take it easy at this unique and tranquil getaway. Enjoy the unique experience of nature in your bedroom and living room : -) Comfortable cabin. (glamping). Access to the river. Panoramic view. Very quiet, very zen. Massages and osteopathy upon request.

Mansion on Organic Farm with Heated Pool
Relax with the whole family and friends up to 30 people in this cozy house on an organic farm with animals, crops, tilapia fishing, coffee, rivers, we have a heated pool, a 120-meter roofed terrace for you to celebrate your special occasions.

Cabana Vergara Santa Fe
Kick back and relax on this 2 acre ( 1 hectare) private mountain side property, on the Santa Maria River. Equipped with all the amenities you will need to make your stay a home away from home!

Casa Nuevo San Juan
Easy access from the Panamericana. It is a central area has supermarket, pharmacy, restaurant, hospital availability.
Popular amenities for San Pedro del Espino vacation rentals
Other great vacation rentals in San Pedro del Espino

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Comfortable house close to everything you need

Comfortable rooms in Santiago

Two Bedrooms With Bathroom

La Pinea Lodge

Main room-San Miguel Clean House, Santiago.

relaxing house 8
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