Santee vacation rentals

Book unique vacation rentals, houses, and more on Airbnb

Top-rated vacation rentals in Santee

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in El Cajon

4.99 out of 5 average rating, 151 reviews

Modern mountain guest house. Incredible views

Neighboring San Diego, quaint country living with incredible views minutes from everything, breathtaking sunsets, 20 mins to beach, close by hiking trails, and only 3 minutes hop on the freeway. Full Kitchen, Laundry, and Living area and with beautiful furnishings, a perfect home away from home. Whether traveling for work or play we have had guests stay for a conference in San Diego or just to visit friends and hit the beach a few days, we look forward to you loving our home as much as we do.

Feb 27 – Mar 6

R3,316 ZAR per night

Guest favorite

Guest suite in Santee

4.95 out of 5 average rating, 250 reviews

Spacious 1 bedroom unit w/ king bed & parking

Come relax in this bright & spacious 1 bedroom detached unit with private entrance. This room has a king bed, full bathroom, table & chairs, mini fridge/freezer, microwave, closet w/ hangers, dresser, Tv and beautiful mountain views. La Jolla Beaches, downtown San Diego, the Zoo, and Sea World are 25 minutes away. Santee Lakes is just a short drive away where you can enjoy fishing, paddle boating, splash park, biking and picnic area. Mission Gorge Trails is also located just 5 minutes away.

Jun 26 – Jul 3

R1,621 ZAR per night

Guest favorite

Guesthouse in La Mesa

4.92 out of 5 average rating, 204 reviews

Fig Tree Bungalow

Enjoy your stay in San Diego in this newly renovated guesthouse. Centrally located about a mile from Hwy 8, Hwy 125, and the Grossmont Trolley Station & Transit Center. Only a 15-20 minute drive to downtown, the airport, the beaches, and most of San Diego's other popular tourist attractions. This cozy, two-story, detached unit is located behind my home, and has its own private entrance and partitioned yard for your enjoyment. There's plenty of street parking directly in front of the house.

Jun 20 – 27

R2,418 ZAR per night

Guest favorite

Home in Alpine

4.99 out of 5 average rating, 141 reviews

Fully Fenced Alpine Property with Guest House

Our guest house is located in the back of our personal property & kept private by fencing. Our property is fully fenced & guests have access in & out by using a keypad. We have laundry facilities, a queen size bed in the master bedroom, a sofa sleeper in the living room/kitchen area and a private patio with bbq. We occupy the main home on the property. We have 2 dogs on the property so other animals are not recommended at this location. Children play equipment is not included with Airbnb.

Jan 17 – 24

R2,451 ZAR per night

Guest favorite

Home in La Mesa

4.85 out of 5 average rating, 175 reviews

Newer "Manor Studio"

Centrally located in San Diego County this brand new studio style unit has a private entrance, private patio area and street parking. Furnished with a queen size bed, love seat, full bathroom and kitchen area. One large drawer to accommodate personal items, and a wall rack to hang clothing. There is a smart TV with WiFi streaming capabilities and lots of USB plugs to charge your devices. On street parking in front of unit (no parking in driveway). No Pets allowed. No Hair Dying allowed.

Jun 25 – Jul 2

R2,132 ZAR per night

Guest favorite

Home in La Mesa

4.94 out of 5 average rating, 175 reviews

Cottage in the Garden! New! Modern!

COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

Sep 6 – 13

R2,823 ZAR per night

Guest favorite

Guesthouse in La Mesa

4.99 out of 5 average rating, 164 reviews

SDCannaBnB #1 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our casita is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our casita has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our casita is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Jul 6 – 13

R2,868 ZAR per night

Guest favorite

Guest suite in La Mesa

4.91 out of 5 average rating, 114 reviews

Private & cozy getaway 8min from downtown SD

One bedroom guest house in La Mesa/San Diego with private entry. Also, have an inflatable queen air mattress for another 1-2 sleepers. The two rooms are divided and can be separated with a sliding door and blackout curtains. You got all the basic amenities that you would need such as a mini fridge, keurig coffee maker, smart TV, central heat & AC. Prime location! Only 8 minutes from downtown SD. Come enjoy a memorable stay that has easy access to nearby beaches, nightlife and shopping.

Mar 26 – Apr 2

R2,071 ZAR per night

Guest favorite

Barn in La Mesa

4.95 out of 5 average rating, 315 reviews

Enchanting Barn San Diego/La Mesa

DESCRIPTION: Relax and Enjoy the converted barn that is safe, cozy, and private. The unit has it's own private entrance secured with a Keyless entry lock. Inside is a Cal King therapy foam bed, TV, Blu-ray player, Bluetooth/CD stereo, and additional USB connection. Extra space has a large desk area. The unit has a private bathroom that includes a walk in shower. Freshly washed towels & linens are provided. *we have a pet goat that would love to meet you! Dedicated 5g Internet access

Sep 15 – 22

R2,017 ZAR per night

Guest favorite

Apartment in La Mesa

4.98 out of 5 average rating, 122 reviews

Lovely Hideaway Studio by Village-Private Patio

Enjoy the cool vibe at this unique rustic getaway tucked back on a tree-lined hill 5 minutes above City of La Mesa Village, 20 minutes from downtown San Diego. The studio is on the ground floor of our two-story house. We live on the 2nd floor, and the studio is it's own completely private space. 5 miles to San Diego State University; 16-20 miles to San Diego beaches; 10 miles to Downtown San Diego; 15 miles to Sea World San Diego; and 13 miles to the World Famous San Diego Zoo!

Mar 10 – 17

R1,927 ZAR per night

Guest favorite

Guesthouse in El Cajon

4.98 out of 5 average rating, 190 reviews

Fletcher Hills - modern 1 BR.Easy, no step access.

** 48 hours between check-ins. Thorough cleaning and sanitizing.. Four night minimum stay. Dogs ONLY are welcomed on a case by case basis. They must be house trained and are not permitted on any furniture. If you instant book, you must contact me about your pet within 24 hours. Smoking is permitted in the outside areas - patio, gazebo, yard. Easy freeway access helps any commute to downtown and area attractions. Having your own vehicle is the best way to get around..

Mar 15 – 22

R2,231 ZAR per night

Guest favorite

Apartment in La Mesa

4.97 out of 5 average rating, 139 reviews

Mt. Helix apartment with panoramic views

Mt. Helix apartment with great views from private balcony located centrally in La Mesa on quiet street. Apartment is on 2nd floor of private home on an acre lot. PLEASE NOTE: Apartment is on 2nd floor and an outside staircase is required to enter the apartment. 1 parking space is designated in driveway. Quiet Hours are 10:00pm - 7:00am. No smoking/vaping anywhere on the property.

Aug 17 – 24

R2,035 ZAR per night

Vacation rentals for every style

Get the amount of space that is right for you

Popular amenities for Santee vacation rentals

Gym

BBQ grill

Laptop-friendly workspace

Wifi

Air conditioning

Stay near Santee's top sights

Santee Trolley Square23 locals recommend

Walmart13 locals recommend

Carlton Oaks Country Club3 locals recommend

Santee Drive In Theatre7 locals recommend

Greek Chicken3 locals recommend

Olive Garden Italian Restaurant16 locals recommend

Other great vacation rentals in Santee

Guest favorite

Guesthouse in La Mesa

4.97 out of 5 average rating, 167 reviews

Cozy Coop with a View

Oct 3 – 10

R2,679 ZAR per night

Guest favorite

Home in Lakeside

5.0 out of 5 average rating, 28 reviews

Terra Mesa - Charming Retreat

Aug 18 – 25

R1,882 ZAR per night

Guest favorite

Guest suite in Lakeside

5.0 out of 5 average rating, 74 reviews

Cozy, secure, and quiet studio in Lakeside

Sep 27 – Oct 4

R2,132 ZAR per night

Guest favorite

Home in Lakeside

5.0 out of 5 average rating, 12 reviews

The Morey de Prieto Surf Ranch

Jan 24 – 31

R2,865 ZAR per night

Superhost

Home in El Cajon

4.93 out of 5 average rating, 27 reviews

Lovely Unique Retro house with beautiful yard

Oct 28 – Nov 4

R2,355 ZAR per night

Guest favorite

Guesthouse in El Cajon

5.0 out of 5 average rating, 14 reviews

Cozy Hillside Retreat with View

Jun 11 – 18

R2,354 ZAR per night

Guest favorite

Home in Lakeside

4.88 out of 5 average rating, 51 reviews

Anna’s Happy Place

Dec 6 – 13

R2,665 ZAR per night

Superhost

Tiny home in La Mesa

4.86 out of 5 average rating, 35 reviews

Tiny House of Tiny Things

May 3 – 10

R1,965 ZAR per night

Show all

Other great vacation rentals in Santee

Guest favorite

Guesthouse in La Mesa

5.0 out of 5 average rating, 16 reviews

Guesthouse w/Outdoor Paradise

Oct 24 – 31

R2,752 ZAR per night

Guest favorite

Guest suite in El Cajon

4.98 out of 5 average rating, 54 reviews

California Dreamin’ at our Coastal-Inspired Suite

Jul 28 – Aug 4

R2,701 ZAR per night

Guest favorite

Guesthouse in La Mesa

5.0 out of 5 average rating, 37 reviews

Secluded, tranquil 1-bedroom in plumeria paradise

Oct 15 – 22

R2,807 ZAR per night

Guest favorite

Guesthouse in La Mesa

5.0 out of 5 average rating, 46 reviews

ino Mt. Helix

Aug 19 – 26

R2,482 ZAR per night

Guest favorite

Guesthouse in El Cajon

4.92 out of 5 average rating, 53 reviews

Hilltop Casita Mount Helix

Jul 7 – 14

R1,860 ZAR per night

Guest favorite

Tiny home in La Mesa

5.0 out of 5 average rating, 96 reviews

Casita de Pueblo - Private Yard, La Mesa Village

Jan 14 – 21

R2,479 ZAR per night

Guest favorite

Guest suite in La Mesa

4.86 out of 5 average rating, 79 reviews

La Mesa Granny Flat

Aug 3 – 10

R2,219 ZAR per night

Guest favorite

Guesthouse in La Mesa

5.0 out of 5 average rating, 39 reviews

Beautiful Bright Mt. Helix Studio

Jan 19 – 26

R2,517 ZAR per night

Show all

Quick stats about vacation rentals in Santee

Total rentals
100 properties
Rentals with dedicated workspaces
50 properties have a dedicated workspace
Rentals with a pool
40 properties have a pool
Pet-friendly rentals
20 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
2.3K reviews

Frequently Asked Questions

Are there house rentals with a dedicated workspace in Santee?
Yes! Work meets play with ease at over 20 house rentals in Santee featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there Santee house rentals on Airbnb with pools?
Yes! Dive into the perfect getaway at one of over 20 house rentals with pools in Santee, available on Airbnb. Make a splash and soak up the sun in style!
How much does it cost to stay in condo rentals in Santee?
Experience the best of Santee with our condo rentals, starting at about $60 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do apartment rentals in Santee have air conditioning?
Absolutely! We offer over 10 apartment rentals with air conditioning in Santee. Enjoy a tailored experience with all the comforts you desire.
Are there pet-friendly house rentals in Santee?
Four-legged friends are welcome in Santee. Choose from more than 10 house rentals for guests traveling with pets.
Are there family-friendly house rentals in Santee?
Santee has more than 20 family-friendly house rentals. Amenities on the property may include high chairs, travel cribs, or strollers.
Do condo rentals in Santee have wifi?
Absolutely! We offer over 10 condo rentals with wifi in Santee. Enjoy a tailored experience with all the comforts you desire.
What are the most popular amenities for Private Suite Rentals in Santee?
Enhance your stay in our Private Suite Rentals with the most popular amenities: over 10 homes with air conditioning, over 10 homes with wifi, and more. Indulge in the ultimate retreat, tailored to your preferences.

Santee vacation rentals

Top-rated vacation rentals in Santee

Vacation rentals for every style

Houses

Hotels

Unique stays

Popular amenities for Santee vacation rentals

Stay near Santee's top sights

Other great vacation rentals in Santee

Guesthouse in La Mesa

Home in Lakeside

Guest suite in Lakeside

Home in Lakeside

Home in El Cajon

Guesthouse in El Cajon

Home in Lakeside

Tiny home in La Mesa

Other great vacation rentals in Santee

Guesthouse in La Mesa

Guest suite in El Cajon

Guesthouse in La Mesa

Guesthouse in La Mesa

Guesthouse in El Cajon

Tiny home in La Mesa

Guest suite in La Mesa

Guesthouse in La Mesa

Quick stats about vacation rentals in Santee

Total rentals

Rentals with dedicated workspaces

Rentals with a pool

Pet-friendly rentals

Family-friendly rentals

Total number of reviews

Frequently Asked Questions

Are there house rentals with a dedicated workspace in Santee?

Are there Santee house rentals on Airbnb with pools?

How much does it cost to stay in condo rentals in Santee?

Do apartment rentals in Santee have air conditioning?

Are there pet-friendly house rentals in Santee?

Are there family-friendly house rentals in Santee?

Do condo rentals in Santee have wifi?

What are the most popular amenities for Private Suite Rentals in Santee?

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